Novel Platforms For Drug Delivery Applications

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Novel Platforms for Drug Delivery Applications

Sangita Das,Sabu Thomas,Partha Pratim Das

Author : Sangita Das,Sabu Thomas,Partha Pratim Das
Publisher : Woodhead Publishing
Page : 695 pages
File Size : 47,5 Mb
Release : 2022-11-08
Category : Medical
ISBN : 9780323913782

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Novel Platforms for Drug Delivery Applications by Sangita Das,Sabu Thomas,Partha Pratim Das Pdf

Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology. Provides an up-to-date single resource on novel drug delivery platforms, a rapidly evolving field of research Covers a broad range of materials, systems and release mechanisms, including in vivo and in vitro studies Describes the synthesis, properties, formulation and application of various novel drug delivery systems

Advanced Drug Delivery

Ashim Mitra,Chi H. Lee,Kun Cheng

Author : Ashim Mitra,Chi H. Lee,Kun Cheng
Publisher : John Wiley & Sons
Page : 844 pages
File Size : 47,6 Mb
Release : 2013-08-26
Category : Medical
ISBN : 9781118662847

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Advanced Drug Delivery by Ashim Mitra,Chi H. Lee,Kun Cheng Pdf

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Fundamentals and Applications of Controlled Release Drug Delivery

Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone

Author : Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 44,9 Mb
Release : 2011-12-15
Category : Medical
ISBN : 9781461408819

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Fundamentals and Applications of Controlled Release Drug Delivery by Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone Pdf

This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.

Drug Delivery

Anya M Hillery,Kinam Park

Author : Anya M Hillery,Kinam Park
Publisher : CRC Press
Page : 634 pages
File Size : 43,9 Mb
Release : 2016-09-15
Category : Medical
ISBN : 9781482217742

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Drug Delivery by Anya M Hillery,Kinam Park Pdf

This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches. Features: Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation Describes the most recent, emerging, and innovative technologies of drug delivery Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems—crucial considerations in order to achieve licensing approval for these new technologies

Drug Delivery Aspects

Ranjita Shegokar

Author : Ranjita Shegokar
Publisher : Academic Press
Page : 268 pages
File Size : 49,9 Mb
Release : 2020-03-27
Category : Business & Economics
ISBN : 9780128218501

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Drug Delivery Aspects by Ranjita Shegokar Pdf

Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses engineering and large-scale manufacturing of nanocarriers Considers preclinical, regulatory and ethical guidelines on nanoparticles Contains in-depth discussions on delivery of biologics, vaccines and sterilisation Industrial view on solid dispersions, milling techniques

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

Ryan F. Donnelly,Thakur Raghu Raj Singh

Author : Ryan F. Donnelly,Thakur Raghu Raj Singh
Publisher : John Wiley & Sons
Page : 290 pages
File Size : 50,5 Mb
Release : 2015-09-28
Category : Science
ISBN : 9781118734513

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Novel Delivery Systems for Transdermal and Intradermal Drug Delivery by Ryan F. Donnelly,Thakur Raghu Raj Singh Pdf

This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

Controlled Drug Delivery Systems

Emmanuel C. Opara

Author : Emmanuel C. Opara
Publisher : CRC Press
Page : 526 pages
File Size : 51,9 Mb
Release : 2020-02-28
Category : Medical
ISBN : 9780429582752

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Controlled Drug Delivery Systems by Emmanuel C. Opara Pdf

This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies. Where appropriate delivery vehicles and relevant release of specific agents in any of these categories in clinical application will be discussed. All chapters will highlight the translational aspects of the various technologies discussed and will provide insights into the advantages of such delivery systems over current ones in clinical or research use. Each technology reviewed in this book will have significant potential to improve patients' lives by enhancing the therapeutic efficacy of drugs. This book: Discusses the various factors that mitigate effective oral insulin delivery and the current status of research efforts to overcome these barriers along with recent clinical projections Examines the advantages and disadvantages of each drug delivery system Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract. In view of these wide-ranging technological areas, and the up-to-date discussions of opportunities and challenges associated with these applications, the book should provide readers from technology, materials science, pharmacology and clinical disciplines with very valuable information.

Drug Delivery

Binghe Wang,Longqin Hu,Teruna J. Siahaan

Author : Binghe Wang,Longqin Hu,Teruna J. Siahaan
Publisher : John Wiley & Sons
Page : 740 pages
File Size : 52,9 Mb
Release : 2016-04-18
Category : Science
ISBN : 9781118833360

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Drug Delivery by Binghe Wang,Longqin Hu,Teruna J. Siahaan Pdf

Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Drug Delivery Applications of Noninvasive Imaging

Chun Li,Mei Tian

Author : Chun Li,Mei Tian
Publisher : John Wiley & Sons
Page : 422 pages
File Size : 51,5 Mb
Release : 2013-10-14
Category : Medical
ISBN : 9781118356838

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Drug Delivery Applications of Noninvasive Imaging by Chun Li,Mei Tian Pdf

Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics, biodistribution, bioavailability, local concentration, and clearance of drug substances for the treatment of human disease, most notably cancer. Written by a team of international experts, this book examines the use of quantitative imaging techniques in designing and evaluating novel drug delivery systems and applications. Drug Delivery Applications of Noninvasive Imaging offers a full arsenal of tested and proven methods, practices and guidance, enabling readers to overcome the many challenges in creating successful new drug delivery systems. The book begins with an introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitative analysis Imaging drugs and drug carriers at the site of action, including low-molecular weight radiopharmaceuticals, peptides and proteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routes other than intravenous injection, such as pulmonary and oral delivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drug development and drug delivery Chapters are based on a thorough review of the current literature as well as the authors' firsthand experience working with imaging techniques for the development of novel drug delivery systems. Presenting state-of-the-technology applications of imaging in preclinical and clinical evaluation of drug delivery systems, Drug Delivery Applications of Noninvasive Imaging offers cost-effective strategies to pharmaceutical researchers and students for developing drug delivery systems that accurately target a broad range of disease conditions.

Nanotechnology and Drug Delivery, Volume One

José L. Arias

Author : José L. Arias
Publisher : CRC Press
Page : 380 pages
File Size : 51,7 Mb
Release : 2014-08-04
Category : Medical
ISBN : 9781466599482

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Nanotechnology and Drug Delivery, Volume One by José L. Arias Pdf

Pharmacotherapy is often limited by the inefficient activity and severe toxicity of drug molecules. Nanotechnology offers a revolutionary and definitive approach for the efficient delivery of drug molecules to non-healthy tissues and cells. This first volume of a series of two volumes analyzes the basics in the development of drug-loaded nanoplatforms, the so-called nanomedicines. Special attention is given to physicochemical engineering, pharmacokinetics, biocompatibility and biodegradability, representative nanoplatforms (based on lipids, polymers, cyclodextrins, metals, carbon, silica, iron oxides, etc.), and advanced nano-engineering strategies for passive, ligand-mediated, and/or stimuli-sensitive drug delivery and release.

Novel Drug Delivery Systems and Regulatory Affairs

Sudhakar Yajaman & Jayaveera K.N.

Author : Sudhakar Yajaman & Jayaveera K.N.
Publisher : S. Chand Publishing
Page : 128 pages
File Size : 48,6 Mb
Release : 2014
Category : Medical
ISBN : 9788121942577

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Novel Drug Delivery Systems and Regulatory Affairs by Sudhakar Yajaman & Jayaveera K.N. Pdf

Sustainable Approach to Protective Nanocoatings

Garg, Rajni,Anjum, Ansar

Author : Garg, Rajni,Anjum, Ansar
Publisher : IGI Global
Page : 461 pages
File Size : 49,7 Mb
Release : 2024-02-27
Category : Technology & Engineering
ISBN : 9798369331378

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Sustainable Approach to Protective Nanocoatings by Garg, Rajni,Anjum, Ansar Pdf

It is essential to harness the potential of nanotechnology in a rapidly evolving industrial environment. As industries grapple with the demand for more advanced, efficient, and sustainable solutions, the intricate amalgamation of chemistry, materials science, physics, biology, and technology in nanotechnology emerges as both a beacon of promise and a complex puzzle. The groundbreaking book, Sustainable Approach to Protective Nanocoatings, serves as a transformative solution. Tailored for academic scholars seeking comprehensive insights, this book navigates the labyrinth of nanotechnology with precision, offering a roadmap for leveraging nanostructured materials and coatings to meet the demands of the modern industrial world. By seamlessly weaving together the intricate tapestry of research methodologies, applications, and technological advances, the book emerges as an indispensable resource for those poised at the intersection of academia and industry.

Nanotechnology in Drug Delivery

Saurabh Bhatia

Author : Saurabh Bhatia
Publisher : Apple Academic Press
Page : 0 pages
File Size : 51,8 Mb
Release : 2016
Category : Drug delivery systems
ISBN : 177188360X

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Nanotechnology in Drug Delivery by Saurabh Bhatia Pdf

This book provides the fundamental understanding of the peptide and protein drug delivery systems with a special focus on their nanotechnology applications. Addressing an increasing interest in peptide and protein drug delivery systems, this book provides a comprehensive review and assessment of conventional and nonconventional routes of administration.

Evaporative Coolers for the Postharvest Management of Fruits and Vegetables

Charles Oluwaseun Adetunji,Daniel Ingo Hefft,Duncan Onyango Mbuge,Tilahun Seyoum Workneh

Author : Charles Oluwaseun Adetunji,Daniel Ingo Hefft,Duncan Onyango Mbuge,Tilahun Seyoum Workneh
Publisher : Academic Press
Page : 480 pages
File Size : 41,6 Mb
Release : 2023-04-27
Category : Technology & Engineering
ISBN : 9780323886215

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Evaporative Coolers for the Postharvest Management of Fruits and Vegetables by Charles Oluwaseun Adetunji,Daniel Ingo Hefft,Duncan Onyango Mbuge,Tilahun Seyoum Workneh Pdf

Evaporative Coolers for the Postharvest Management of Fruits and Vegetables covers world demand for food of high quality without chemical preservatives and with extended shelf life. The book provides the practical application of evaporative coolers, with a strong focus on postharvest management and fruit/vegetable science as high moisture foods are highly perishable. Special emphasis is laid on the impact of the evaporative coolant structure on the nutritional and food safety content of fresh produce. Moreover, the book covers the effect of evaporative coolant structure towards the reduction of spoilage microorganisms responsible for the spoilage of post-harvest losses of various fruits and vegetables. Edited by a team of specialists, this title also helps people dealing with microbiology understand how this simple technology can help improve product quality for communities that currently lack access to cooling or have unreliable power supplies. Thoroughly explores shelf-life extensions that can be achieved when applying evaporative cooling Covers postharvest management through evaporative cooling Brings food and consumer science aspects from evaporative cooled fruits and vegetables Presents information on the interaction of edible coatings towards the extension of climacteric and non-climacteric fruits

Drug Delivery

Binghe Wang,Teruna J. Siahaan,Richard A. Soltero

Author : Binghe Wang,Teruna J. Siahaan,Richard A. Soltero
Publisher : John Wiley & Sons
Page : 463 pages
File Size : 46,8 Mb
Release : 2005-04-29
Category : Science
ISBN : 9780471475712

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Drug Delivery by Binghe Wang,Teruna J. Siahaan,Richard A. Soltero Pdf

An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers' ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. Bringing together contributions by leading international experts, Drug Delivery covers the entire field in a systematic but concise way. It begins with an in-depth review of key fundamentals, such as physiochemical and biological barriers; drug delivery pathways; metabolism; drug formulation; pharmacokinetic and pharmacodynamic issues; and more. The remainder of the book is devoted to the systematic examination-including overviews, timely examples, and extensive references-of a host of specific subjects, including: * Receptor-mediated drug delivery * Prodrug delivery approaches * Oral protein and peptide drug delivery * Gene therapy and gene delivery * Ultrasound-mediated drug delivery * Polycationic peptides and proteins in drug delivery * Pulmonary drug delivery * Antibody-directed drug delivery * Efflux transporters in drug excretion * Intellectual property issues in drug delivery

Novel Platforms For Drug Delivery Applications

Novel Platforms for Drug Delivery Applications by Sangita Das,Sabu Thomas,Partha Pratim Das Pdf

Advanced Drug Delivery by Ashim Mitra,Chi H. Lee,Kun Cheng Pdf

Fundamentals and Applications of Controlled Release Drug Delivery by Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone Pdf

Drug Delivery by Anya M Hillery,Kinam Park Pdf

Drug Delivery Aspects by Ranjita Shegokar Pdf

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery by Ryan F. Donnelly,Thakur Raghu Raj Singh Pdf

Controlled Drug Delivery Systems by Emmanuel C. Opara Pdf

Drug Delivery by Binghe Wang,Longqin Hu,Teruna J. Siahaan Pdf

Drug Delivery Applications of Noninvasive Imaging by Chun Li,Mei Tian Pdf

Nanotechnology and Drug Delivery, Volume One by José L. Arias Pdf

Novel Drug Delivery Systems and Regulatory Affairs by Sudhakar Yajaman & Jayaveera K.N. Pdf

Sustainable Approach to Protective Nanocoatings by Garg, Rajni,Anjum, Ansar Pdf

Nanotechnology in Drug Delivery by Saurabh Bhatia Pdf

Evaporative Coolers for the Postharvest Management of Fruits and Vegetables by Charles Oluwaseun Adetunji,Daniel Ingo Hefft,Duncan Onyango Mbuge,Tilahun Seyoum Workneh Pdf

Drug Delivery by Binghe Wang,Teruna J. Siahaan,Richard A. Soltero Pdf

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