Developments And Applications In Solubility

Author : Trevor M Letcher
Publisher : Royal Society of Chemistry
Page : 432 pages
File Size : 45,9 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847557681

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Developments and Applications in Solubility by Trevor M Letcher Pdf

Solubility is fundamental to most areas of chemistry and is one of the most basic of thermodynamic properties. It underlies most industrial processes. Bringing together the latest developments and ideas, Developments and Applications in Solubility covers many varied and disparate topics. The book is a collection of work from leading experts in their fields and covers the theory of solubility, modelling and simulation, industrial applications and new data and recent developments relating to solubility. Of particular interest are sections on: experimental, calculated and predicted solubilities; solubility phenomena in 'green' quaternary mixtures involving ionic liquids; molecular simulation approaches to solubility; solubility impurities in cryogenic liquids and carbon dioxide in chemical processes. The book is a definitive and comprehensive reference to what is new in solubility and is ideal for researcher scientists, industrialists and academics

Author : Trevor M. Letcher
Publisher : Royal Society of Chemistry
Page : 433 pages
File Size : 46,7 Mb
Release : 2007
Category : Science
ISBN : 9780854043729

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Development and Applications in Solubility by Trevor M. Letcher Pdf

Solubility is fundamental to most areas of chemistry and is one of the most basic of thermodynamic properties. It underlies most industrial processes. Bringing together the latest developments and ideas, Developments and Applications in Solubility covers many varied and disparate topics. The book is a collection of work from leading experts in their fields and covers the theory of solubility, modelling and simulation, industrial applications and new data and recent developments relating to solubility. Of particular interest are sections on: experimental, calculated and predicted solubilities; solubility phenomena in 'green' quaternary mixtures involving ionic liquids; molecular simulation approaches to solubility; solubility impurities in cryogenic liquids and carbon dioxide in chemical processes. The book is a definitive and comprehensive reference to what is new in solubility and is ideal for researcher scientists, industrialists and academics

Author : Rajesh Krishna,Lawrence Yu
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 45,8 Mb
Release : 2007-09-20
Category : Medical
ISBN : 9780387723792

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Biopharmaceutics Applications in Drug Development by Rajesh Krishna,Lawrence Yu Pdf

The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Author : Trevor M. Letcher
Publisher : Elsevier
Page : 492 pages
File Size : 43,7 Mb
Release : 2007-04-20
Category : Science
ISBN : 0080481035

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Thermodynamics, Solubility and Environmental Issues by Trevor M. Letcher Pdf

Environmental problems are becoming an important aspect of our lives as industries grow apace with populations throughout the world. Thermodynamics, Solubility and Environmental Issues highlights some of the problems and shows how chemistry can help to reduce these them. The unifying theme is Solubility – the most basic and important of thermodynamic properties. This informative book looks at the importance and applications of solubility and thermodynamics, in understanding and in reducing chemical pollution in the environment. Written by experts in their respective fields and representing the latest findings in this very important and broad area. A collection of twenty-five chapters cover a wide range of topics including; mining, polymer manufacture and applications, radioactive wastes, industries in general, agro-chemicals, soil pollution and biology, together with the basic theory and recent developments in the modelling of environmental pollutants. Latest research into solving some of the most important environmental problems Covering new technologies, new chemicals and new processes eg, biodegradable polymers, ionic liquids and green chemistry Contains the basic theories and underlying importance of solubility

Author : Anonim
Publisher : Elsevier
Page : 434 pages
File Size : 54,7 Mb
Release : 2022-12-02
Category : Science
ISBN : 9780323884884

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Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development by Anonim Pdf

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable “go-to reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods. Experienced HPLC users who are interested in developing knowledge in orthogonal separation techniques, as well as newcomers to the field of separation science, will find this text particularly useful. Chapters address where SFC may fit the analytical needs of the pharmaceutical industry and alert the readers as to where the technique will not fit. Readers will gain an understanding of how and where SFC may be applied and adapted more routinely across the pharmaceutical industry as a ‘green’ way of undertaking separation opportunities and challenges. Areas within the pharmaceutical industry include early drug discovery, process chemistry, and late stage development and manufacturing. Describes approaches to SFC column and mobile phase selection for method development for both analytical and preparative tasks Gives practical examples of how analytical SFC enables the monitoring of synthetic reactions including unstable intermediates, chiral and achiral polar reactants and products across small and large modalities Provides need-focused case studies for pharmaceutical analysts, process chemists, and contract chemistry facilities that can benefit from monitoring or purifying polar intermediates, mutagenic impurities, nitrosamines and other reaction by-products including excipients and metabolites

Author : Sean Ekins
Publisher : John Wiley & Sons
Page : 840 pages
File Size : 54,5 Mb
Release : 2006-07-11
Category : Medical
ISBN : 9780470037225

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Computer Applications in Pharmaceutical Research and Development by Sean Ekins Pdf

A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

Author : Hui Yao,Zhanping You,Dawei Wang,Feng Li,Yue Hou,Jie Ji
Publisher : Frontiers Media SA
Page : 214 pages
File Size : 47,7 Mb
Release : 2021-10-22
Category : Technology & Engineering
ISBN : 9782889715411

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Development and Application of Bituminous Materials for Civil Infrastructures by Hui Yao,Zhanping You,Dawei Wang,Feng Li,Yue Hou,Jie Ji Pdf

Author : Amit Kumar Nayak,Kalyan Kumar Sen
Publisher : Elsevier
Page : 759 pages
File Size : 55,8 Mb
Release : 2023-12-09
Category : Medical
ISBN : 9780323972468

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Dosage Forms, Formulation Developments and Regulations by Amit Kumar Nayak,Kalyan Kumar Sen Pdf

Dosage Forms, Formulation Developments and Regulations, Volume One in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics, with an original approach focused on technology, novelties and future trends in the field. The book discusses the most recent developments in pharmaceutical preformulation and formulation studies, biopharmaceutics and novel pharmaceutical formulations, regulatory affairs, and good manufacturing practices. Exciting areas such as formulation strategies, optimization techniques, the biopharmaceutical classification system, and pharmaceutical aerosols are included. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students in pharmaceutics. Examines trends and recent technologies in dosage, formulation and regulation Contains contributions from leading experts in academia, research, industry and regulatory agencies Includes high-quality illustrations, flow charts and tables for easy understanding of concepts Discusses practical examples and research case studies

Author : Mike S. Lee
Publisher : John Wiley & Sons
Page : 257 pages
File Size : 45,8 Mb
Release : 2003-08-01
Category : Science
ISBN : 9780471459309

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LC/MS Applications in Drug Development by Mike S. Lee Pdf

Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include: Proteomics Glycoprotein Mapping Natural Products Dereplication Lead Identification Screening Open-Access LC/MS In Vitro Drug Screening Written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce, LC/MS Applications in Drug Development is the premier reference on the subject.

Author : Shadpour Mallakpour,Chaudhery Mustansar Hussain
Publisher : Elsevier
Page : 518 pages
File Size : 40,7 Mb
Release : 2022-06-23
Category : Technology & Engineering
ISBN : 9780128242599

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Industrial Applications of Nanocrystals by Shadpour Mallakpour,Chaudhery Mustansar Hussain Pdf

Approx.494 pages Approx.494 pages

Author : Tapan K. Das
Publisher : John Wiley & Sons
Page : 380 pages
File Size : 51,5 Mb
Release : 2014-02-27
Category : Medical
ISBN : 9781118354681

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Biophysical Methods for Biotherapeutics by Tapan K. Das Pdf

With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development. • Helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods • Chapters organized according to the sequential nature of the drug development process • Helps formulation, analytical, and bioanalytical scientists in pharma and biotech better understand and usestrengths and limitations of biophysical methods • Explains how to use biophysical methods, the information obtained, and what needs to be presented in a regulatory filing, assess impact on quality and immunogenicity • With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development.

Author : Istvan Benedek
Publisher : CRC Press
Page : 630 pages
File Size : 51,5 Mb
Release : 2005-11-02
Category : Science
ISBN : 9781420027525

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Developments In Pressure-Sensitive Products by Istvan Benedek Pdf

Since the first groundbreaking edition of Developments in Pressure-Sensitive Products was introduced in 1998, heavy research has resulted in substantial progress in the field. Fully updated and expanded to reflect this activity, Developments in Pressure-Sensitive Products, Second Edition provides a detailed overview of the entire range of pressure-

Author : J. Braunstein,Gleb Mamantov,G. P. Smith
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 46,5 Mb
Release : 2013-04-17
Category : Science
ISBN : 9781475706628

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Advances in Molten Salt Chemistry by J. Braunstein,Gleb Mamantov,G. P. Smith Pdf

Author : Paul Manning Wehn
Publisher : Unknown
Page : 1074 pages
File Size : 48,8 Mb
Release : 2005
Category : Electronic
ISBN : STANFORD:36105119731110

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The Development and Application of Rhodium-catalyzed C-H Amination Reactions in the Synthesis of Bromopyrrole Alkaloids by Paul Manning Wehn Pdf

Author : Zahid Amjad
Publisher : Springer Science & Business Media
Page : 261 pages
File Size : 41,9 Mb
Release : 2007-05-08
Category : Technology & Engineering
ISBN : 9780306469152

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Water Soluble Polymers by Zahid Amjad Pdf

This volume contains a series of papers originally presented at the symposium on Water Soluble Polymers: Solution Properties and Applications, sponsored by the Division of Colloids and Surface Chemistry of the American Chemical Society. The symposium took place in Las Vegas City, Nevada on 9 to 11th September, 1997 at the 214th American Chemical Society National Meeting. Recognized experts in their - spective fields were invited to speak. There was a strong attendance from academia, g- ernment, and industrial research centers. The purpose of the symposium was to present and discuss recent developments in the solution properties of water soluble polymers and their applications in aqueous systems. Water soluble polymers find applications in a number of fields of which the following may be worth mentioning: cosmetics, detergent, oral care, industrial water treatment, g- thermal, wastewater treatment, water purification and reuse, pulp and paper production, sugar refining, and many more. Moreover, water soluble polymers play vital role in the oil industry, especially in enhanced oil recovery. Water soluble polymers are also used in ag- culture and controlled release pharmaceutical applications. Therefore, a fundamental kno- edge of solution properties of these polymers is essential for most industrial scientists. An understanding of the basic phenomena involved in the application of these polymers, such as adsorption and interaction with different substrates (i. e. , tooth enamel, hair, reverse - mosis membrane, heat exchanger surfaces, etc. ) is of vital importance in developing high performance formulations for achieving optimum efficiency of the system.