Diagnostic And Prognostic Markers In Liver Cirrhosis Book Edition Of Disease Markers
Diagnostic And Prognostic Markers In Liver Cirrhosis Book Edition Of Disease Markers Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Diagnostic And Prognostic Markers In Liver Cirrhosis Book Edition Of Disease Markers book. This book definitely worth reading, it is an incredibly well-written.
Diagnostic and Prognostic Markers in Liver Cirrhosis - Book Edition of Disease Markers by S. Augustin,J. Genesca Pdf
Suitable for those involved in the diagnosis and treatment of liver disease, this title explores the importance of diagnostic tools and the role of different prognostic markers in the different stages and clinical complications of liver cirrhosis.
Biomarkers in Liver Disease by Victor R. Preedy,Vinood B. Patel Pdf
In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.
Liver cirrhosis represents one of the major challenges for most physicians and surgeons on a global scale. This book provides practicing hepatologists, gastroenterologists and liver surgeons with a valuable tool in their efforts to understand the (molecular) mechanisms involved, be updated regarding the newest and less invasive diagnostic methods, and educate themselves about the challenges involved in the management of liver cirrhosis and its complications. The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience on a variety of different aspects of liver cirrhosis, giving us a well-rounded overview.
Chronic Liver Failure by Pere Ginès,Patrick S Kamath,Vicente Arroyo Pdf
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
GI/Liver Secrets Plus: First South Asia Edition - E-book by Peter R. McNally Pdf
Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series® style makes this book a valuable addition to your library! Easily locate important information with bulleted lists, tables, boxes, short answers, and a highly detailed index to expedite reference. Access a broad range of topics that focus on all of today's most common GI and liver disorders and their management.
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Complications of Cirrhosis, An Issue of Clinics in Liver Disease, E-Book by Andres Cardenas,Thomas Reiberger Pdf
In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editors Drs. Andres Cardenas and Thomas Reiberger have created an up-to-date monograph on the complications of cirrhosis. They have secured top experts to contribute clinical review articles on the following topics: Non-invasive Detection of CSPH in cACLD; Prevention of First Decompensation in ACLD; Treatment of Acute Variceal Bleeding in 2020: When to Use TIPS; Prevention of Variceal Bleeding and Rebleeding by NSBB: A Tailored Approach; The Role of Hepatic Venous Pressure Gradient (HVPG); Measurement in the Management of Cirrhosis; Bacterial Infections in Cirrhosis as a Cause or Consequence of Decompensation; Nutrition in Chronic Liver Disease; Diagnosis and Management of Hepatic Encephalopathy; Discriminating Acute Decompensation from Acute-on-Chronic Liver; Management of Severe and Refractory Ascites; Monitoring Renal Function and Therapy of HRS patients with Cirrhosis; Coagulopathy in Cirrhosis; and Current Concepts of Cirrhotic Cardiomyopathy. Hepatologists will come away with the information they need to manage these patients.
Author : Brian I. Carr Publisher : Springer Science & Business Media Page : 752 pages File Size : 53,9 Mb Release : 2009-10-03 Category : Medical ISBN : 9781603273763
Hepatocellular cancer is the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today’s hepatologists and medical and surgical oncologists.
Sleisenger and Fordtran's Gastrointestinal and Liver Disease by Mark Feldman,Lawrence S. Friedman,Lawrence J. Brandt Pdf
For nearly 50 years, Sleisenger & Fordtran’s Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you’ll quickly and easily find the information you need. Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. Offers reliable coverage of key topics such as Barrett’s esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. Employs a consistent, templated, format throughout for quick retrieval of information. Includes monthly updates online, as well as more than 20 procedural videos.
Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Author : Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri Publisher : Cambridge University Press Page : 995 pages File Size : 47,7 Mb Release : 2007-05-07 Category : Medical ISBN : 9781139464031
Liver Disease in Children by Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri Pdf
Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.
This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.
Author : Lawrence S. Friedman,Emmet B. Keeffe Publisher : Elsevier Health Sciences Page : 535 pages File Size : 54,7 Mb Release : 2011-08-03 Category : Medical ISBN : 9781455723164
Handbook of Liver Disease E-Book by Lawrence S. Friedman,Emmet B. Keeffe Pdf
The Handbook of Liver Disease, 3rd Edition, by Drs. Lawrence S. Friedman and Emmet B. Keeffe, gives you quick reference to the most recent diagnostic and treatment options for patients with liver disorders. International authorities share the latest clinical findings and procedures to help you expertly manage illnesses like hepatitis B and C and hepatocellular carcinoma, as well as apply new practices like genetic testing, noninvasive imaging techniques, and so much more. Quickly access updated information on all aspects of liver disease including new drugs, therapy trials, and post-transplant conditions with this full-color, templated edition–in print and online at www.expertconsult.com. Expedite diagnostic and therapeutic decision making with a highly templated outline format that uses full-color illustrations, tables, algorithms and figures, key point boxes, and alert symbols to present information at a glance. Apply some of the latest treatments for liver disease including the role of pretreatment IL28B testing for patients with hepatitis B and C; radiofrequency ablation and sorafenib in cases of hepatocellular carcinoma; the use of the drug rifaximin to treat hepatic encephalopathy; and much more. Make optimal use of genetic testing to assess your patients’ risk of metabolic liver disease and to personalize treatment regimens for chronic hepatitis C. Offer your liver transplantation patients the best prognosis and follow-up with the latest information on outcomes and the management of complications. Use blood test panels and noninvasive imaging techniques to evaluate the degree of liver fibrosis. Make informed treatment decisions with the latest clinical trial results for portal hypertension, autoimmune liver diseases, acute liver failure, and hepatic infections. Search the complete text online, download all the images, and test your knowledge with 200 board-style review questions at www.expertconsult.com.
Practical Hepatic Pathology: A Diagnostic Approach E-Book by Romil Saxena Pdf
A volume in the popular Pattern Recognition Series, Practical Hepatic Pathology: A Diagnostic Approach features completely updated and reorganized content, resulting in a truly practical guide to understanding liver pathology. Dr. Romil Saxena presents interpretation of liver biopsies according to a pattern-based approach that begins with recognition of the predominant histological pattern of injury, followed by identification of secondary features and appropriate work-up that lead you away from pitfalls to the best diagnosis. Unique "visual index" at the beginning of the book references the exact chapter and specific page needed for in-depth diagnostic guidance. Superb, high-quality, full-color images illustrate pathognomonic features and common variations. Features comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules, including clinical features, laboratory tests, imaging findings and differential diagnosis. Coverage of the clinical aspects of liver transplantation allows you to understand the pathology and practice of this procedure. Virtual Microscope provides your own personal set of over 300 liver slides accessible anywhere, any time on your favorite digital device. Navigate around and zoom in and out to savor these exceptionally high quality whole slide images covering everything from the normal liver to rare challenging cases. New section on Evolving Concepts keeps you abreast of new paradigms in liver diseases such as reversal of fibrosis, heterogeneity of cirrhosis, and biphenotypic primary liver cell carcinoma. Reorganized Table of Contents is even more intuitive.
Diagnosis and Treatment of Rare Gynecologic Cancers by Michael Frumovitz,Mario M. Leitao Jr.,Preetha Ramalingam Pdf
Offering a one-stop guide to recognition and therapeutic decision making, Diagnosis and Treatment of Rare Gynecologic Cancers fills a gap in the medical literature on uncommon ovarian, uterine, cervical, and vulvovaginal cancers and trophoblastic diseases. This authoritative text, edited by Drs. Michael Frumovitz, Mario Leitao, and Preetha Ramalingam, has been authored by internationally recognized experts from top institutions such as MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center. Each chapter covers different cancer subtypes and has been reviewed by an oncologist and a pathologist. Provides up-to-date clinical guidance on assessment and therapeutic options for patients with rare gynecologic malignancies. Presents information in a templated, easy-to-read format. Each chapter includes an introductory clinical case followed by epidemiology of disease, pathologic assessment, basic science/molecular/translational research, work-up of newly diagnosed disease, staging, treatment of newly diagnosed disease, treatment of recurrent disease, potential therapeutic targets, and a case resolution. Includes diagnostic and treatment algorithms for each form of cancer. Contains numerous anatomical figures, radiographs, photographs, and tables for quick visual reference.
Biochemistry, 5th Edition (Updated and Revised Edition)-E-Book by U Satyanarayana,U Chakrapani Pdf
is an amalgamation of medical and basic sciences, and is comprehensively written and later revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences students, and others studying Biochemistry as one of the subjects. This book fully satisfies the revised MCI competency-based curriculum. is the first textbook on Biochemistry in English with multicolor illustrations by an Asian author. The use of multicolors is for a clear understanding of the complicated structures and reactions. is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances and with theoretical discussions being supplemented with illustrations, tables, biomedical concepts, clinical correlates, and case studies for an easy understanding of Biochemistry. has each chapter beginning with a four-line verse followed by the text with clinical correlates, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. All this will help the students to master the subject and face the examinations with confidence. provides the most recent and essential information on Molecular Biology and Biotechnology, and current topics such as Diabetes, Cancer, Free Radicals and Antioxidants, Prostaglandins, etc. describes a wide variety of case studies (77) with biomedical correlations. They are listed at the end of relevant chapters for immediate reference, quick review, and better understanding of Biochemistry. contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.