Diagnostic And Therapeutic Advances In Hematologic Malignancies

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Diagnostic and Therapeutic Advances in Hematologic Malignancies

Author : Martin S. Tallman,Leo I. Gordon
Publisher : Springer Science & Business Media
Page : 383 pages
File Size : 46,9 Mb
Release : 2007-11-23
Category : Medical
ISBN : 9780585385716

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Diagnostic and Therapeutic Advances in Hematologic Malignancies by Martin S. Tallman,Leo I. Gordon Pdf

There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constant evolving concepts in this area.

Advances in Hematologic Malignancies

Author : Gamal Abdul Hamid
Publisher : BoD – Books on Demand
Page : 178 pages
File Size : 49,9 Mb
Release : 2019-12-04
Category : Medical
ISBN : 9781789239416

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Advances in Hematologic Malignancies by Gamal Abdul Hamid Pdf

The book Advances in Hematologic Malignancies presents new knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic, and genomic changes that have influenced the current outlook toward hematological malignancies. This book provides a unique, practical, and concise guide that is focused on the must-know points of diagnosis, prognosis, therapeutic management, and cutting edge clinical trial opportunities for each hematologic malignancy. Advances in Hematologic Malignancies is designed and organized as an essential reference source for the hematologist, hematologic oncologist, hematopathologist, and trainee.

Hematologic Malignancies in Adults

Author : MiKaela M. Olsen,Laura J. Zitella
Publisher : Unknown
Page : 0 pages
File Size : 54,8 Mb
Release : 2013
Category : Hematopoietic system
ISBN : 1935864262

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Hematologic Malignancies in Adults by MiKaela M. Olsen,Laura J. Zitella Pdf

More than 180 years since Thomas Hodgkin identified the first hematologic malignancy, nurses are still learning the best ways to treat patients with these complex cancers. Hematologic Malignancies in Adults gives you comprehensive information on treatments, complications, and toxicity management for your everyday practice. The book focuses on the management of disease-related manifestations and treatment-related side effects and toxicities. You'll find details on forms of hematologic malignancies, including leukemia and lymphoma, Hodgkin lymphoma, mature T-cell and NK-cell neoplasms, and multiple myeloma. Also included is a chapter on vascular access and a listing of drugs used in the treatment of hematologic malignancies. The management of patients with myeloid and lymphoid neoplasms is unique, complex, and vital to ensuring successful outcomes and improved quality of life. This book gives you every tool you need to keep pace with the advances in medicine and science as you trea

Handbook of Hematologic Malignancies

Author : David A. Sallman, MD,Ateefa Chaudhury, MD,Johnny Nguyen, MD,Ling Zhang, MD,Alan F. List, MD
Publisher : Springer Publishing Company
Page : 404 pages
File Size : 45,7 Mb
Release : 2016-11-28
Category : Medical
ISBN : 9781617052705

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Handbook of Hematologic Malignancies by David A. Sallman, MD,Ateefa Chaudhury, MD,Johnny Nguyen, MD,Ling Zhang, MD,Alan F. List, MD Pdf

Handbook of Hematologic Malignancies provides a unique, practical, and concise guide focused on the must-know points of diagnosis, prognosis, therapeutic management, and cutting edge clinical trial opportunities for each hematologic malignancy. With an ever-increasing growth of evidence and a significant expansion of available treatment options for patients with hematologic disease, remaining current and up-to-date can be extremely challenging for practicing clinicians. This comprehensive subspecialty handbook is designed and organized for the busy hematologist, hematologic oncologist, hematopathologist, and trainee in mind. Every chapter is richly illustrated with color figures and flow diagrams, and contains helpful tables on differential diagnosis, prognostic scoring systems and therapeutic options. A concise case-based review for testing pathologic diagnosis and clinical knowledge for each chapter is included for digital download online and in the e-book. Written by experienced clinicians at the world-renowned Moffitt Cancer Center in Tampa, Florida, as well as contributions from leading academicians throughout the country, this handbook is an essential resource for anyone diagnosing, treating, or managing patients with hematologic malignancy. KEY FEATURES: Contains clear prognostic and diagnostic tools (e.g., tables/flow diagrams/pathology images) with emphasis on key differential diagnoses and diagnostic dilemmas Easy to use treatment recommendations with bullet point format and key references. Discusses the future of patient management based on practice changing clinical trials Includes access to digitally downloadable case-based clinical scenarios and questions with high resolution pathology images linked to each individual chapter

Management of Hematologic Malignancies

Author : Susan O'Brien,Julie M. Vose,Hagop M. Kantarjian
Publisher : Cambridge University Press
Page : 527 pages
File Size : 50,5 Mb
Release : 2010-11-18
Category : Medical
ISBN : 9781139493659

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Management of Hematologic Malignancies by Susan O'Brien,Julie M. Vose,Hagop M. Kantarjian Pdf

Hematologic malignancies were the first human cancers to be studied in depth at the molecular level, and recent years have seen important advances in treatment. This comprehensive reference book covers the full range of hematologic malignancies, including all subtypes of leukemias, lymphomas, and plasma cell dyscrasias. Authored by internationally known experts, each chapter emphasizes diagnostic work-up, staging, and therapeutic approaches. Up-to-date hematopathology, treatment, and outcomes data are presented in a way which is directly applicable to patient care. Highly illustrated with color images, graphs, flowcharts and treatment algorithms, the book is perfect for quick clinical reference as well as providing detailed reference lists for further study. With its authoritative and practical focus and visually stimulating presentation, this is a key text for hematology and oncology fellows, physicians, oncology nurses, physician assistants and other healthcare workers in the field of oncology.

Childhood Cancer and Functional Impacts Across the Care Continuum

Author : National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability
Publisher : Unknown
Page : 128 pages
File Size : 51,6 Mb
Release : 2021-09-09
Category : Electronic
ISBN : 0309683491

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Childhood Cancer and Functional Impacts Across the Care Continuum by National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Pdf

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Rare Hematological Malignancies

Author : Stephen M. Ansell
Publisher : Springer Science & Business Media
Page : 435 pages
File Size : 42,9 Mb
Release : 2007-11-17
Category : Medical
ISBN : 9780387737447

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Rare Hematological Malignancies by Stephen M. Ansell Pdf

This hugely practical work will be a bible in the pocket of hematologists and other practitioners everywhere, covering as it does malignant hematologic diseases that physicians will only occasionally see. It provides accurate, up-to-date information on the disease biology as well as practical recommendations concerning disease management. Information concerning these diseases, and particularly regarding their management, can be extremely difficult to find. Not any more.

Allogeneic Stem Cell Transplantation

Author : Hillard M. Lazarus,Mary J. Laughlin
Publisher : Springer Science & Business Media
Page : 881 pages
File Size : 41,6 Mb
Release : 2010-03-02
Category : Medical
ISBN : 9781597454780

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Allogeneic Stem Cell Transplantation by Hillard M. Lazarus,Mary J. Laughlin Pdf

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Diagnostic and Therapeutic Advances in Pediatric Oncology

Author : David O. Walterhouse,Susan L. Cohn
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 48,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461557678

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Diagnostic and Therapeutic Advances in Pediatric Oncology by David O. Walterhouse,Susan L. Cohn Pdf

The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.

Advances in Breast Cancer Management, 2nd edition

Author : William J. Gradishar,William C. Wood
Publisher : Springer Science & Business Media
Page : 216 pages
File Size : 48,8 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781475731477

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Advances in Breast Cancer Management, 2nd edition by William J. Gradishar,William C. Wood Pdf

The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh discusses the consequences of estrogen deprivation and the ways of ameliorating secondary symptoms and the potential long-term morbidity. Drs. Haigh and Guiliano review the sentinel lymph node biopsy technique including results from their extensive experience. Dr. Abram Recht places into perspective the potential benefit of post-mastectomy radiotherapy and reviews recent trials that address this issue. Dr. Dennis Slamon takes from us from the laboratory to the clinic in explaining the development of Herceptin as a paradigm for therapy targeted to specific molecular characteristics of breast cancer tumor cells. Drs. Nieto, Shpall, Crump and Pritchard offer different perspectives on the future of high-dose chemotherapy with stem cell transplantation as a treatment for breast cancer patients. Drs.

Advances in Allogeneic Hematopoietic Stem Cell Transplantation

Author : Richard K. Burt,Mary M. Brush
Publisher : Springer
Page : 419 pages
File Size : 46,7 Mb
Release : 2012-11-28
Category : Medical
ISBN : 9781461549871

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Advances in Allogeneic Hematopoietic Stem Cell Transplantation by Richard K. Burt,Mary M. Brush Pdf

The field of hematopoietic stem cell transplantation is rapidly evolving. Realization that hematopoietic stem cells give rise to the immune compartment has resulted in clinical trials of hematopoietic stem cell transplantation for patients with autoimmune diseases. Allogeneic hematopoietic transplants are a form of adoptive immunotherapy resulting in beneficial graft versus tumor effects. Large numbers of hematopoietic cells can be collected with ease. Therefore, a renewable source of cells for ex vivo genetic manipulations is readily available. Multiple trials combining hematopoietic transplants and gene therapy are in progress. One such application is the infusion of allogeneic lymphocytes containing a suicide gene to abort graft versus host disease. Hematopoietic stem cell transplantation is in reality the clinical and practical application of cellular therapy. Hematopoietic transplant physicians are by design or by practical application evolving into cell and gene therapy specialists. The excitement and enthusiasm in hematopoietic transplantation is that it offers a door to the future. A future not of drugs or titrating poisonous chemotherapy but rather of cellular and gene therapy. 1 ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR HEMATOLOGIC DISEASES Martin Korbling University o/Texas MD. Anderson Cancer Center, Houston, Texas 77030 INTRODUCTION Circulating hematopoietic stem cells have emerged as an alternative to bone marrow (BM) stem cells for allografting. For many years the reconstitutive potential of circulating stem cells was questioned; peripheral blood stem cells (PBSC) were even characterized a waste product (1).

Advances in Breast Cancer Management

Author : William J. Gradishar,William C. Wood
Publisher : Springer Science & Business Media
Page : 182 pages
File Size : 40,9 Mb
Release : 2007-11-29
Category : Medical
ISBN : 9780387731612

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Advances in Breast Cancer Management by William J. Gradishar,William C. Wood Pdf

This volume highlights many of the important advances that have improved our understanding of the biology and therapeutics of breast cancer. The initial discussion focuses on the evolving understanding of the genetics of breast cancer. In addition to the well known genetic mutations BRCA1 and BRCA2, other mutations that have recently been identified are discussed.

Liver-Directed Therapy for Primary and Metastatic Liver Tumors

Author : Mark S. Talamonti,Sam G. Pappas
Publisher : Springer Science & Business Media
Page : 342 pages
File Size : 42,7 Mb
Release : 2001-11-30
Category : Medical
ISBN : 0792375238

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Liver-Directed Therapy for Primary and Metastatic Liver Tumors by Mark S. Talamonti,Sam G. Pappas Pdf

Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique multi-modality approach to management of all types of primary and secondary liver tumors. The biology of liver cancers, state of the art radiologic imaging and novel, non-surgical interventional strategies are given. There is an in depth analysis of surgical options including transplantation, resection, interstitial ablation techniques and liver-directed chemotherapy for hepatocellular carcinoma, bile duct cancers, and colorectal and neuroendocrine liver metastases. Because of the unique and comprehensive examination of liver tumors, this work is an excellent resource for surgical, transplant and medical oncologists, surgeons, gastroenterologists, and radiologists.

HIV & HTLV-I Associated Malignancies

Author : Joseph A. Sparano
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461516019

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HIV & HTLV-I Associated Malignancies by Joseph A. Sparano Pdf

Infection with the human immunodeficiency virus (HIV) and human T-cell lymphotropic virus type I (HTLV-I) is known to be associated with an increased risk of neoplastic disorders, especially Kaposi's sarcoma and aggressive B-cell lymphoma for the former, and T-cell lymphoma for the latter. The information obtained from the study of these infections has led to remarkable advances in our understanding of the immune system, as well as the biology of human neoplasms. The management of malignant diseases in such patients also poses substantial challenges to clinicians. This book provides an overview of the epidemiology, biology, clinical features, and clinical management of neoplasms occurring in such individuals. It is an important resource for clinicians treating these diseases, and for basic scientists who have an interest in this field.

Kidney Cancer

Author : Robert A. Figlin
Publisher : Springer Science & Business Media
Page : 260 pages
File Size : 42,6 Mb
Release : 2003-10-31
Category : Medical
ISBN : 1402074573

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Kidney Cancer by Robert A. Figlin Pdf

Kidney cancer is a heterogenous disease. This book covers: -new surgical approaches which are becoming the standard, i.e., nephon sparing, laporascopic, minimally invasive techniques; -new staging and prognostic capabilities; -evolving therapeutic options include, cell based vaccine, gene and antibody therapy; -molecular genetics allow for a better understanding of the various types of kidney cancer. Kidney Cancer is a comprehensive review covering present and future surgical approaches, staging and prognostic factors, currently accepted and future plans for prevention, diagnosis and treatment. Contributing authors to this book are internationally recognized specialists in this disease. This book will be useful to the specialist (oncologist and urologist), primary care physicians, patients and family members dealing with kidney cancer.