Dietary Induction Models Of Nutritional Disorders In Rodents

Author : Jailane de Souza Aquino,Naís Lira Soares,Kamila Sabino Batista,Omar Guzmán-Quevedo
Publisher : Cambridge Scholars Publishing
Page : 206 pages
File Size : 42,5 Mb
Release : 2023-06-16
Category : Medical
ISBN : 9781527504875

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Dietary Induction Models of Nutritional Disorders in Rodents by Jailane de Souza Aquino,Naís Lira Soares,Kamila Sabino Batista,Omar Guzmán-Quevedo Pdf

This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.

Author : Jailane de Souza,Naís Lira Soares,Kamila Sabino Batista,Omar Guzmán-Quevedo
Publisher : Unknown
Page : 0 pages
File Size : 47,6 Mb
Release : 2023-07
Category : Electronic
ISBN : 1527504867

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Dietary Induction Models of Nutritional Disorders in Rodents by Jailane de Souza,Naís Lira Soares,Kamila Sabino Batista,Omar Guzmán-Quevedo Pdf

This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.

Author : National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition
Publisher : National Academies Press
Page : 188 pages
File Size : 42,9 Mb
Release : 1995-02-01
Category : Science
ISBN : 9780309051262

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Nutrient Requirements of Laboratory Animals, by National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition Pdf

In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.

Author : Patrick C. Even,Sam Virtue,Nicholas M. Morton,Gilles Fromentin,Robert K. Semple
Publisher : Frontiers Media SA
Page : 161 pages
File Size : 53,9 Mb
Release : 2018-02-15
Category : Electronic
ISBN : 9782889454259

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Are Rodent Models Fit for Investigation of Human Obesity and Related Diseases? by Patrick C. Even,Sam Virtue,Nicholas M. Morton,Gilles Fromentin,Robert K. Semple Pdf

Not only developed countries, but also most developing areas of the world, have experienced a surge in obesity prevalence over recent decades. Obesity complications are now among the leading causes of premature mortality, encompassing conditions such as coronary heart disease, stroke, and type 2 diabetes. This places a heavy burden on contemporary healthcare systems. While rodent models have limitations as experimental models of human obesity-related disease, study of rats and mice either spontaneously prone - or resistant - to obesity, or genetically engineered to illuminate underlying mechanisms has yielded key information about the metabolic defects linked to obesity, and their associated diseases. This topic includes both original research studies and reviews of the use of animal studies in specific areas of obesity-related disease. Various methodological approaches are discussed, with evaluation of the extent to which use of animal models has facilitated progress, or, conversely, has proved a cul de sac in investigation of human disease mechanisms. Consideration is also given to future strategies to use such rodent models optimally to enhance comprehension and treatment of pandemic human obesity-related diseases.

Author : Cynthia Petrie Smith
Publisher : Unknown
Page : 62 pages
File Size : 46,6 Mb
Release : 1992
Category : Animal models in research
ISBN : MINN:31951D01002584L

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Animal Models of Disease by Cynthia Petrie Smith Pdf

Author : Anonim
Publisher : Unknown
Page : 1120 pages
File Size : 41,8 Mb
Release : 1990
Category : Agriculture
ISBN : UIUC:30112102098123

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Bibliography of Agriculture by Anonim Pdf

Author : Alice Sabatino,Carla Maria Avesani
Publisher : Frontiers Media SA
Page : 120 pages
File Size : 45,8 Mb
Release : 2022-01-10
Category : Medical
ISBN : 9782889740055

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Nutritional Aspects of Kidney Disease by Alice Sabatino,Carla Maria Avesani Pdf

Author : Anton C. Beynen,C. E. West
Publisher : Unknown
Page : 204 pages
File Size : 47,9 Mb
Release : 1988
Category : Medical
ISBN : UOM:39015014475431

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Use of Animal Models for Research in Human Nutrition by Anton C. Beynen,C. E. West Pdf

Author : Anonim
Publisher : Unknown
Page : 722 pages
File Size : 52,6 Mb
Release : 1976
Category : Agriculture
ISBN : WISC:89047810684

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Quick Bibliography Series by Anonim Pdf

Author : Randy L. Jirtle,Frederick L. Tyson
Publisher : Springer Science & Business Media
Page : 361 pages
File Size : 44,6 Mb
Release : 2013-05-13
Category : Medical
ISBN : 9783642368271

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Environmental Epigenomics in Health and Disease by Randy L. Jirtle,Frederick L. Tyson Pdf

There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this two volume book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome. Consequently, epigenetic research promises to markedly improve our ability to diagnosis, prevent, and treat the pathological conditions of humans; however, it also introduces unique legal and ethical issues. This volume highlights the correlation between environmental factors and complex diseases, such as autism, addiction, neurological diseases, diabetes, obesity and cancer. It concludes with a chapter on legal and ethical implications of epigenetics. ​

Author : M. Sue Houston,Jeffrey M. P. Holly,Eva L. Feldman
Publisher : Springer Science & Business Media
Page : 359 pages
File Size : 42,8 Mb
Release : 2004-08-04
Category : Medical
ISBN : 9781592597956

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IGF and Nutrition in Health and Disease by M. Sue Houston,Jeffrey M. P. Holly,Eva L. Feldman Pdf

A benchmark review on how specific nutrients or adverse nutritional states impact the components of the IGF (Insulin-like Growth Factor) system and affect human health and disease. The authors describe the fundamentals of the IGF system, explain its basic mechanisms of action, illuminate its essential role in physical development across the life span, and highlight the link between normal and abnormal cellular growth resulting in tumor formation. They also fully examine the clinical aspects of nutrition and IGF, from pre- and postnatal development through old age, in the maintenance of normal metabolism, bone, and muscle health, and their role in pathological states. Special attention is given to critical illness, diabetes, gastrointestinal diseases, kidney failure, endocrine dysfunctions, cardiovascular disease, neurological disorders, and cancer, as well as to their potential for IGF therapy.

Author : National Heart, Lung, and Blood Institute
Publisher : Unknown
Page : 624 pages
File Size : 54,8 Mb
Release : 1978
Category : Cardiovascular system
ISBN : IND:30000099201760

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Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute by National Heart, Lung, and Blood Institute Pdf

Author : Sergej M. Ostojic
Publisher : Academic Press
Page : 714 pages
File Size : 48,9 Mb
Release : 2022-10-20
Category : Science
ISBN : 9780323984522

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Molecular Nutrition and Mitochondria by Sergej M. Ostojic Pdf

Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction. Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food. Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction. Describes the fundamentals of mitochondria physiology and considers the methods used to evaluate mitochondrial imbalance in clinical practice Provides broad biochemical and metabolic background on nutritional deficits found in mitochondrial dysfunction Explores the prevention and treatment of various inherited and acquired disorders associated with mitochondrial dysfunction Discusses the link between the dosage for each nutrient (nutritional vs. pharmacological) and the clinical effect Features a dedicated section on whole-diet interventions and mitochondrial function

Author : Anna Alisi,Manlio Vinciguerra,Andrea Masotti
Publisher : Frontiers Media SA
Page : 180 pages
File Size : 46,5 Mb
Release : 2020-12-02
Category : Science
ISBN : 9782889661480

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Role of Epigenetic Modifications on Diet-Induced Metabolic Diseases by Anna Alisi,Manlio Vinciguerra,Andrea Masotti Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Gokhan Dalgin,Rebecca Ann Wingert,Ryan M. Anderson
Publisher : Frontiers Media SA
Page : 157 pages
File Size : 44,6 Mb
Release : 2019-12-06
Category : Electronic
ISBN : 9782889632480

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Zebrafish in Development and Disease by Gokhan Dalgin,Rebecca Ann Wingert,Ryan M. Anderson Pdf

There are only a few vertebrate systems that can be used to model human diseases for biomedical discovery. The zebrafish model provides key advantages over existing models. Their externally developing embryos provide high-throughput non-invasive imaging, chemical screening, forward and reverse genetics, and their regeneration capacity make zebrafish a valuable system for novel discovery. Developmental studies using zebrafish has influenced discoveries in many human health-related conditions. This Research Topic covers all aspects of zebrafish studies, providing developmental mechanisms to human health conditions. The aim of the Research Topic was to foster a platform to bring all levels of zebrafish research including but not limited to development, disease, regeneration, drug screening, bioinformatics and Omics studies.