Diffuse Gastric Cancer

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Diffuse Gastric Cancer

Tiago Biachi de Castria,Rodrigo Santa Cruz Guindalini
Diffuse Gastric Cancer Book PDF

Author : Tiago Biachi de Castria,Rodrigo Santa Cruz Guindalini
Publisher : Springer
Page : 81 pages
File Size : 44,8 Mb
Release : 2018-09-08
Category : Medical
ISBN : 9783319952345

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Diffuse Gastric Cancer by Tiago Biachi de Castria,Rodrigo Santa Cruz Guindalini Pdf

We live in an era of personalized medicine and the knowledge about pathophysiology of diffuse gastric cancer has had many advances. Thus, the role of this work is to clarify what is new from diagnosis to treatment of this disease in order to treat patients in the most tailored manner as possible. Almost all phase III trials in gastric cancer have been performed without taking in consideration histologic subtypes, i.e. they have disregarded the differences between diffuse gastric cancer and general gastric cancer. However, the clinical practice reveals that diffuse gastric cancer is a completely distinct disease, with an aggressive course and generally worse prognosis. The loss of cohesion between tumor cells due to the loss of E-cadherin synthesis is the critical point on the oncogenesis of diffuse gastric cancer and is at the root of its marked heredity. This book intends to give special attention to Diffuse Gastric Cancer as a particular oncological entity, differentiating it from general gastric cancer, exploring and discussing all its peculiarities, and addressing the basic aspects (pathology and genetics) along with the most recent therapeutic alternatives for this condition.

Research Focus on Gastric Cancer

Dorothy C. Cardinni
Research Focus on Gastric Cancer Book PDF

Author : Dorothy C. Cardinni
Publisher : Nova Publishers
Page : 314 pages
File Size : 40,7 Mb
Release : 2008
Category : Medical
ISBN : 1600217265

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Research Focus on Gastric Cancer by Dorothy C. Cardinni Pdf

This book presents important leading-edge research on stomach cancer. Stomach cancer (also called "gastric cancer") is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2% (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables. Infection with H. pylori is the main risk factor in about 80% or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90% of individuals with stomach cancer, with a five year survival rate of 75% in those diagnosed in early stages and less than 30% of those diagnosed in late stages.

Spotlight on Familial and Hereditary Gastric Cancer

Giovanni Corso,Franco Roviello
Spotlight on Familial and Hereditary Gastric Cancer Book PDF

Author : Giovanni Corso,Franco Roviello
Publisher : Springer Science & Business Media
Page : 219 pages
File Size : 55,6 Mb
Release : 2013-06-04
Category : Medical
ISBN : 9789400765702

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Spotlight on Familial and Hereditary Gastric Cancer by Giovanni Corso,Franco Roviello Pdf

In this book we have taken a comprehensive look at the subject of familial and hereditary gastric tumors. In particular, the aim of this novel editorial work is to propose the correct management of hereditary diffuse gastric cancer patients, focusing in particular on E-cadherin germline mutations, clinical criteria definition, genetic screening and molecular mechanisms, pathology and microscopic features, surgical treatment and clinical approach for asymptomatic mutation carriers. We also describe other inherited predispositions involving gastric carcinoma.

Gastric Cancer Research Trends

Marilyn B. Tompkins
Gastric Cancer Research Trends Book PDF

Author : Marilyn B. Tompkins
Publisher : Nova Publishers
Page : 344 pages
File Size : 50,8 Mb
Release : 2007
Category : Medical
ISBN : 1600217257

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Gastric Cancer Research Trends by Marilyn B. Tompkins Pdf

Stomach cancer (also called gastric cancer) is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2 percent (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables.Infection with H. pylori is the main risk factor in about 80 percent or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90 percent of individuals with stomach cancer, with a five year survival rate of 75 percent in those diagnosed in early stages and less than 30 percent of those diagnosed in late stages. This book presents new and important research from around the world.

Gastric Cancer

Dongfeng Tan,Gregory Lauwers
Gastric Cancer Book PDF

Author : Dongfeng Tan,Gregory Lauwers
Publisher : Lippincott Williams & Wilkins
Page : 369 pages
File Size : 46,7 Mb
Release : 2011
Category : Medical
ISBN : 9781608316175

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Gastric Cancer by Dongfeng Tan,Gregory Lauwers Pdf

Advances in Surgical Pathology: Gastric Cancer provides a concise, updated review of the pathological characteristics of gastric cancer, with an emphasis on exploring practical issues and recent developments. The book features current and emerging concepts in the field of gastric cancer, a disease whose management requires a multidisciplinary approach in which pathology plays a key role. Its six sections cover the essential histopathology of gastric cancer as well as related topics such as imaging evaluation, molecular diagnosis, and personalized treatment, among other areas of interest. Individual chapters written by international experts in the fields of pathology, gastrointestinal medical oncology, cancer epidemiology, and gastrointestinal radiology, address the fundamental issues surrounding gastric cancer, including its epidemiology, basic diagnostic features, differential diagnoses, pitfalls and complications, and treatments. Endoscopic evaluation and histology correlation are emphasized. The screening, clinical management, and treatment of gastric cancer are summarized in related book sections. Recent findings regarding the roles of immunohistochemistry and molecular testing in the diagnosis, prognosis, and personalized treatment of gastric cancer are also reviewed. The book also includes current knowledge regarding the molecular alteration of gastric cancer carcinogenesis and its impact on patient care.

Management of Gastric Cancer

Paul H. Sugarbaker
Management of Gastric Cancer Book PDF

Author : Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 405 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461538820

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Management of Gastric Cancer by Paul H. Sugarbaker Pdf

Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Molecular Features Distinguishing Gastric Cancer Subtypes

Valli De Re
Molecular Features Distinguishing Gastric Cancer Subtypes Book PDF

Author : Valli De Re
Publisher : MDPI
Page : 327 pages
File Size : 46,5 Mb
Release : 2018-12-07
Category : Electronic books
ISBN : 9783038974048

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Molecular Features Distinguishing Gastric Cancer Subtypes by Valli De Re Pdf

This book is a printed edition of the Special Issue "Molecular Features Distinguishing Gastric Cancer Subtypes" that was published in IJMS

Hereditary Gastric and Breast Cancer Syndrome

Giovanni Corso,Paolo Veronesi,Franco Roviello
Hereditary Gastric and Breast Cancer Syndrome Book PDF

Author : Giovanni Corso,Paolo Veronesi,Franco Roviello
Publisher : Springer Nature
Page : 412 pages
File Size : 43,6 Mb
Release : 2023-03-17
Category : Medical
ISBN : 9783031213175

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Hereditary Gastric and Breast Cancer Syndrome by Giovanni Corso,Paolo Veronesi,Franco Roviello Pdf

In this book the editors and authors provide a comprehensive overview on basic research and clinical aspects of hereditary breast and gastric tumors. In particular, this updated editorial work aims to suggest guidelines for the clinical management of patients with hereditary diffuse gastric and lobular breast cancer. Special attention is given to E-cadherin (CDH1 gene) germline mutations, genetic screening approaches, the underlying molecular mechanisms and pathological and microscopic features. In addition, the book aims to define clinical criteria for genetic screening, and highlights current surgical treatment and clinical approaches for asymptomatic mutation carriers. Other inherited predispositions involving gastric and breast carcinoma are discussed as well. Divided into eight sections, the book starts by providing an epidemiological overview of gastric and breast cancers, followed by a section dealing with new descriptions of genetic pathways in hereditary cancer predispositions. The third section focuses on pathological features of the diseases, in an effort to bridge the gap between discovery and cancer therapy development. Subsequent sections of the book are dedicated to endoscopy and breast imaging, as well as risk-reducing surgeries to curb the risk of developing cancer. The sixth section focuses on the generation of ideas for the identification of targets and novel treatment strategies. Finally, in the seventh section the authors share the story of two patients and their experiences with the diagnosis and treatment of hereditary cancer. This multidisciplinary book brings together multiple disciplines in science and technology; specifically, medicine, surgery and biology. The majority of authors are members of the International Gastric Cancer Linkage Consortium (IGCLC) and of the European Cancer Prevention Organization (EJCPO), with relevant experience in this context. Offering in-depth insights into hereditary cancers, this book represents essential reading for students, researchers, and specialists who want to extend their knowledge on hereditary gastric and breast cancers.

Gastric Cancer

Vivian E. Strong
Gastric Cancer Book PDF

Author : Vivian E. Strong
Publisher : Springer
Page : 333 pages
File Size : 53,7 Mb
Release : 2015-06-10
Category : Medical
ISBN : 9783319158266

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Gastric Cancer by Vivian E. Strong Pdf

This volume provides the most comprehensive and complete resource available on all aspects of gastric cancer and it’s management. The book covers topics such as oncologic approaches to staging, treating, and following patients, filling a critical need for resource materials on these areas. As multidisciplinary care is an integral part of gastric cancer treatment, this text is unique in including a renowned group of expert authors from a variety of disciplines, including pathology, gastroenterology, medical oncology, surgery and clinical genetics. In addition, authors from an international pool of gastric cancer experts have covered the breadth of practice and understanding globally. Edited and organized by an expert from one of the most highly respected cancer institutions in the country, Gastric Cancer: Principles and Practice is an expert review of this field, serving as a valuable reference for physicians in training and in practice, as well as for researchers who are interested in the scope of issues and advances in this important malignancy.

Pathology of the Gastrointestinal Tract

Fátima Carneiro,Paula Chaves,Arzu Ensari
Pathology of the Gastrointestinal Tract Book PDF

Author : Fátima Carneiro,Paula Chaves,Arzu Ensari
Publisher : Springer
Page : 0 pages
File Size : 45,6 Mb
Release : 2017-06-28
Category : Medical
ISBN : 3319405594

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Pathology of the Gastrointestinal Tract by Fátima Carneiro,Paula Chaves,Arzu Ensari Pdf

This book covers the complete field of the pathology of the Gastrointestinal tract - from Abetalipoproteinemia to Zollinger-Ellison Syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

Gastric Cancer: the 25-year R-Evolution

Giovanni de Manzoni,Franco Roviello
Gastric Cancer the 25 year R Evolution Book PDF

Author : Giovanni de Manzoni,Franco Roviello
Publisher : Springer Nature
Page : 276 pages
File Size : 50,9 Mb
Release : 2021-10-15
Category : Medical
ISBN : 9783030731588

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Gastric Cancer: the 25-year R-Evolution by Giovanni de Manzoni,Franco Roviello Pdf

Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.

Morson and Dawson's Gastrointestinal Pathology

David W. Day,Jeremy R. Jass,Ashley B. Price,Neal A. Shepherd,James M. Sloan,Nicholas J. Talbot,Geraint T. Williams,Bryan F. Warren
Morson and Dawson s Gastrointestinal Pathology Book PDF

Author : David W. Day,Jeremy R. Jass,Ashley B. Price,Neal A. Shepherd,James M. Sloan,Nicholas J. Talbot,Geraint T. Williams,Bryan F. Warren
Publisher : John Wiley & Sons
Page : 704 pages
File Size : 47,7 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9780470755303

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Morson and Dawson's Gastrointestinal Pathology by David W. Day,Jeremy R. Jass,Ashley B. Price,Neal A. Shepherd,James M. Sloan,Nicholas J. Talbot,Geraint T. Williams,Bryan F. Warren Pdf

Morson and Dawson's Gastrointestinal Pathology is one of the 'Gold Standards' of pathology textbooks. It has been completely revised to incorporate the latest advances in this rapidly evolving field including the developments in gastric cancer and Helicobacter pylori and the revised classification of other common gastrointestinal conditions. This new edition features a wealth of new material presented in full colour for the first time.

Management of Gastric Cancer, An Issue of Surgical Oncology Clinics - E-Book

Neal Wilkinson
Management of Gastric Cancer An Issue of Surgical Oncology Clinics E Book Book PDF

Author : Neal Wilkinson
Publisher : Elsevier Health Sciences
Page : 204 pages
File Size : 48,5 Mb
Release : 2012-01-28
Category : Medical
ISBN : 9781455743179

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Management of Gastric Cancer, An Issue of Surgical Oncology Clinics - E-Book by Neal Wilkinson Pdf

This issue of Surgical Oncology Clinics of North America, Guest Edited by Neal Wilkinson, MD, is devoted to the Management of Gastric Cancer. Articles in this issue will focus on Epidemiology; Genetics and Prophylactic Surgery; Endoscopic Diagnosis & Staging; Gastric Stromal Tumors (GIST); Management of Early Stage Gastric Cancer; Endoscopic Mucosal Resection (EMR); Tailored Lymphadenectomy; Laparoscopic Resection Gastric Cancer - Western Experience; Gastric Cancer - Eastern Experience; Update of Gastric Cancer Clinical Trials; Preoperative and Postoperative Chemotherapy for Gastric Cancer; and Phase I and II Clinical Trials.

Staging Laparoscopy

P. Hohenberger,K. Conlon
Staging Laparoscopy Book PDF

Author : P. Hohenberger,K. Conlon
Publisher : Springer Science & Business Media
Page : 206 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642562907

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Staging Laparoscopy by P. Hohenberger,K. Conlon Pdf

Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

Gastric Cancer, An Issue of Gastroenterology Clinics

Steven Moss
Gastric Cancer An Issue of Gastroenterology Clinics Book PDF

Author : Steven Moss
Publisher : Elsevier Health Sciences
Page : 276 pages
File Size : 42,8 Mb
Release : 2013-06-28
Category : Medical
ISBN : 9781455771769

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Gastric Cancer, An Issue of Gastroenterology Clinics by Steven Moss Pdf

Gastric cancer is the second most common cause of cancer mortality worldwide. Although the incidence of gastric cancer has declined over the past century in the United States, it remains one of the most common gastrointestinal neoplasms, particularly in immigrants and the socio-economically deprived. Recent years have seen major advances in our understanding of the pathogenesis of gastric cancer (especially regarding the importance of Helicobacter pylori and its associated inflammatory response) and the emergence of adjuvant oncologic therapies of proven benefit for advanced cases, in addition to surgery. As for gastric adenocarcinoma, elucidation of the underlying biology and molecular pathogenesis has led to much progress in the management of two other malignant gastric neoplasms, gastrointestinal stromal tumors and marginal zone B-cell (“MALT ) lymphomas. This monograph highlights these developments, presenting an updated overview of gastric cancer that will be of interest to all practicing gastroenterologists.