Digestive Involvement In Systemic Autoimmune Diseases

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The Digestive Involvement in Systemic Autoimmune Diseases

Manuel Ramos-Casals,Munther Khamashta,Pilar Brito-Zeron,Fabiola Atzeni,Joan Rodes
The Digestive Involvement in Systemic Autoimmune Diseases Book PDF

Author : Manuel Ramos-Casals,Munther Khamashta,Pilar Brito-Zeron,Fabiola Atzeni,Joan Rodes
Publisher : Elsevier
Page : 494 pages
File Size : 40,5 Mb
Release : 2017-01-18
Category : Science
ISBN : 9780444637178

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The Digestive Involvement in Systemic Autoimmune Diseases by Manuel Ramos-Casals,Munther Khamashta,Pilar Brito-Zeron,Fabiola Atzeni,Joan Rodes Pdf

The Digestive System in Systemic Autoimmune Diseases, Second Edition, represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases. This volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations. International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico, and South Africa share their knowledge in this detailed volume. The book provides an overview of our current understanding of digestive disorders in the most common systemic autoimmune diseases. Completely updated, including five new chapters Presents up-to-date information, giving the reader easy access to individual topics in one place Written by leading international clinical and scientific experts on autoimmune and digestive diseases Provides a practical guide to the identification, diagnosis, and treatment of digestive involvement in patients with autoimmune diseases that will be useful for all medical specialties Includes several diseases and conditions not included in other texts, some of which have only recently emerged Designed to serve as a guide to clinical practice

Autoimmune Diseases

Munther A Khamashta,Manuel Ramos-Casals
Autoimmune Diseases Book PDF

Author : Munther A Khamashta,Manuel Ramos-Casals
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 51,9 Mb
Release : 2011-05-26
Category : Medical
ISBN : 9780857293589

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Autoimmune Diseases by Munther A Khamashta,Manuel Ramos-Casals Pdf

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Skills in Rheumatology

Hani Almoallim,Mohamed Cheikh
Skills in Rheumatology Book PDF

Author : Hani Almoallim,Mohamed Cheikh
Publisher : Springer Nature
Page : 562 pages
File Size : 47,6 Mb
Release : 2021-01-05
Category : Medical
ISBN : 9789811583230

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Skills in Rheumatology by Hani Almoallim,Mohamed Cheikh Pdf

This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.

Digestive Involvement in Systemic Autoimmune Diseases

Manuel Ramos-Casals
Digestive Involvement in Systemic Autoimmune Diseases Book PDF

Author : Manuel Ramos-Casals
Publisher : Elsevier
Page : 350 pages
File Size : 51,7 Mb
Release : 2011-09-02
Category : Medical
ISBN : 008055931X

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Digestive Involvement in Systemic Autoimmune Diseases by Manuel Ramos-Casals Pdf

The Digestive System in Systemic Autoimmune Diseases represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases. The volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations. International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico and South Africa share their knowledge in this detailed volume. *One book of leading international clinical and scientific experts on autoimmune and digestive diseases *A practical guide to the identification, diagnosis and treatment of digestive involvement in patients with autoimmune diseases that will be useful for all medical specialties *Several diseases and conditions not included in other text books are included, some of which are of recent emergence *Each chapter is designed to serve as a “Guide to Clinical Practice for each disease

Autoimmune Diseases in Pediatric Gastroenterology

Faruk Hadziselimovic
Autoimmune Diseases in Pediatric Gastroenterology Book PDF

Author : Faruk Hadziselimovic
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 43,6 Mb
Release : 2002-09-30
Category : Medical
ISBN : 0792387783

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Autoimmune Diseases in Pediatric Gastroenterology by Faruk Hadziselimovic Pdf

This book is the proceedings of the Falk Symposium No. 127 on `Autoimmune Diseases in Paediatric Gastroenterology' (IV International Falk Symposium on Paediatric Gastroenterology), held in Basel, Switzerland, on November 8-9, 2001. The symposium focused on the role of the immune system, both the acquired and the innate systems, in inflammatory bowel disease (IBD) in children and adolescents. The innate system has an important fundamental role in host defence by initiating immune responses against potentially deleterious matter. However, a mutation within the innate system may elicit an immune response against the host: hence, an autoimmune response. Chronic autoimmune hepatitis occurs predominantly in young people, and especially in women. Immunological changes are conspicuous. Tissue antibodies are found in a large number of patients. This is a disease of disordered immunoregulation marked by a deficit in suppressor T cells causing the production of autoantibodies against specific hepatocyte surface antigen. Liver membrane protein is found in the sera of patients with autoimmune chronic acute hepatitis and with primary biliary cirrhosis (PBC). The latter condition of progressive granulomatous destruction of intrahepatic bile ducts is, in many respects, analogous to the graft-versus-host syndrome where the immune system has become sensitized to foreign HLA-molecules. Primary sclerosing cholangitis (PSC) is another condition of unknown origin. All parts of the biliary tree can be involved in a chronic, fibrosing, inflammatory process that results in obliteration of the biliary tree and ultimately in biliary cirrhosis. About half of the patients also suffer from ulcerative colitis and rarely from Crohn's disease. Circulating antibodies to some antigens are found in obstructed portal tracts, as well as increased concentrations of biliary immune complexes in patients with PBC. In all three previous Falk symposia on paediatric gastroenterology, attention was focused on the role of the innate immune system in the aetiology of IBD. It has become increasingly clear in recent years that the innate system has a much more important and fundamental role in host defence. The decision to initiate an immune response is one of the major roles of the innate system. Mutations within this system could transform it into becoming constitutively active, resulting in an inflammatory reaction and thus eliciting an autoimmune response. Following an introduction to the basic phenomena of autoimmunity, the proceedings discuss clinical aspects of autoimmune diseases. In particular, current knowledge and the state of the art about the diagnosis and treatment of the autoimmune diseases of the gastrointestinal tract are described by world-renowned experts. The book also contains the short presentations on selected topics, as well as abstracts of the mini-posters read by title, which were included in the symposium.

Pulmonary Involvement in Systemic Autoimmune Diseases

Athol U. Wells,Christopher P. Denton
Pulmonary Involvement in Systemic Autoimmune Diseases Book PDF

Author : Athol U. Wells,Christopher P. Denton
Publisher : Elsevier Science Limited
Page : 297 pages
File Size : 49,8 Mb
Release : 2004
Category : Mathematics
ISBN : 0444516522

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Pulmonary Involvement in Systemic Autoimmune Diseases by Athol U. Wells,Christopher P. Denton Pdf

In this book is found the information essential to diagnosing, managing and treating the lung complications of connective tissue diseases. This is a notoriously difficult area, which continues to puzzle clinicians, despite the fact that these disorders are increasingly frequent (as a result of longer survival in connective tissue disease). In separate chapters, the major connective tissue diseases are reviewed, with detailed discussion of a variety of lung abnormalities, including pleural disease, parenchymal lung disease and pulmonary vascular disease. There are also invaluable overviews of lung histological and CT appearances in these disorders, and a deeply insightful chapter on drug-induced lung disease in connective tissue disease. The emphasis in this book is on accuracy of evaluation and the construction of a logical management plan, based on disease severity and intrinsic progressiveness.

Pathogenesis of Systemic Lupus Erythematosus

Alberta Hoi
Pathogenesis of Systemic Lupus Erythematosus Book PDF

Author : Alberta Hoi
Publisher : Springer Nature
Page : 192 pages
File Size : 43,9 Mb
Release : 2021-11-15
Category : Medical
ISBN : 9783030851613

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Pathogenesis of Systemic Lupus Erythematosus by Alberta Hoi Pdf

The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.

Idiotypes in Medicine: Autoimmunity, Infection and Cancer

R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld
Idiotypes in Medicine Autoimmunity Infection and Cancer Book PDF

Author : R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld
Publisher : Elsevier
Page : 540 pages
File Size : 53,9 Mb
Release : 1997-11-19
Category : Medical
ISBN : 0080534430

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Idiotypes in Medicine: Autoimmunity, Infection and Cancer by R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld Pdf

This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases

Hiromasa Ohira,Kiyoshi Migita
Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases Book PDF

Author : Hiromasa Ohira,Kiyoshi Migita
Publisher : Springer
Page : 200 pages
File Size : 45,9 Mb
Release : 2019-03-28
Category : Medical
ISBN : 9789811365249

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Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases by Hiromasa Ohira,Kiyoshi Migita Pdf

This book presents research outcomes, providing a big picture of rheumatic diseases as systemic conditions, and exploring the correlation between liver dysfunction and gastrointestinal lesions. Each chapter presents the association between major rheumatic diseases and hepato-gastrointestinal lesions, including liver and gastrointestinal involvement in lupus erythematosus, dermatomyositis, systemic sclerosis, Bechet’s disease, and IgG4-related disease. The chapters on PBC-CREST syndrome and immunosuppressive agents broaden readers understanding and enable them to view the diseases from a systematic perspective. Although the disease is rare, it has attracted considerable attention as an intractable disease, and despite the severity of the symptoms, little has been written on the topic. Adopting a multidisciplinary approach, this comprehensive volume thoroughly prepares readers for research in the field of systemic diseases. Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases is a valuable resource not only for hepatologists and rheumatologists, but also clinical residents and medical students.

The Immune System Recovery Plan

Susan Blum
The Immune System Recovery Plan Book PDF

Author : Susan Blum
Publisher : Simon and Schuster
Page : 464 pages
File Size : 43,8 Mb
Release : 2013-04-02
Category : Health & Fitness
ISBN : 9781451695007

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The Immune System Recovery Plan by Susan Blum Pdf

The bestselling book with 100,000 copies in print from one of the most sought-after experts in the field of functional medicine, Dr. Susan Blum, author of Healing Arthritis, shares the four-step program she used to treat her own serious autoimmune condition and help countless patients reverse their symptoms, heal their immune systems, and prevent future illness. DR. BLUM ASKS: • Are you constantly exhausted? • Do you frequently feel sick? • Are you hot when others are cold, or cold when everyone else is warm? • Do you have trouble thinking clearly, aka “brain fog”? • Do you often feel irritable? • Are you experiencing hair loss, dry skin, or unexplained weight fluctuation? • Do your joints ache or swell but you don’t know why? • Do you have an overall sense of not feeling your best, but it has been going on so long it’s actually normal to you? If you answered yes to any of these questions, you may have an autoimmune disease, and this book is the “medicine” you need. Among the most prevalent forms of chronic illness in this country, autoimmune disease affects nearly 23.5 million Americans. This epidemic—a result of the toxins in our diet; exposure to chemicals, heavy metals, and antibiotics; and unprecedented stress levels—has caused millions to suffer from autoimmune conditions such as Graves’ disease, rheumatoid arthritis, Crohn’s disease, celiac disease, lupus, and more. DR. BLUM’S INNOVATIVE METHOD FOCUSES ON: • Using food as medicine • Understanding the stress connection • Healing your gut and digestive system • Optimizing liver function Each of these sections includes an interactive workbook to help you determine and create your own personal treatment program. Also included are recipes for simple, easy-to-prepare dishes to jump-start the healing process. The Immune System Recovery Plan is a revolutionary way for people to balance their immune systems, transform their health, and live fuller, happier lives.

Intestinal Immune System

Soichiro Miura,Ryota Hokari,Shunsuke Komoto
Intestinal Immune System Book PDF

Author : Soichiro Miura,Ryota Hokari,Shunsuke Komoto
Publisher : Morgan & Claypool Publishers
Page : 125 pages
File Size : 47,9 Mb
Release : 2011
Category : Medical
ISBN : 9781615041442

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Intestinal Immune System by Soichiro Miura,Ryota Hokari,Shunsuke Komoto Pdf

These negative regulatory mechanisms of the intestinal immune system are disturbed in certain disease conditions, causing the immunocompetent cells to respond to food components and commensal bacteria by becoming activated and to overproduce inflammatory cytokines and chemokines. These disease conditions include food allergies, such as celiac disease, and the inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, although their exact etiological mechanisms remain to be revealed. --Book Jacket.

Infections in Systemic Autoimmune Diseases

Anonim
Infections in Systemic Autoimmune Diseases Book PDF

Author : Anonim
Publisher : Elsevier
Page : 230 pages
File Size : 43,8 Mb
Release : 2020-03-08
Category : Medical
ISBN : 9780444642189

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Infections in Systemic Autoimmune Diseases by Anonim Pdf

Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who’s who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on Infection problems in systemic autoimmune diseases Provides a practical guide to the safer treatment of infections in patients with autoimmune diseases Includes a number of problems and recommendation that cannot be found in other books Designed as a ‘guide to clinical practice’ for management and risk interventions required by patients with SAD’s

The Heart in Systemic Autoimmune Diseases

Fabiola Atzeni,Andrea Dorea,Mike Nurmohamed,Paolo Pauletto
The Heart in Systemic Autoimmune Diseases Book PDF

Author : Fabiola Atzeni,Andrea Dorea,Mike Nurmohamed,Paolo Pauletto
Publisher : Elsevier
Page : 566 pages
File Size : 42,6 Mb
Release : 2017-02-11
Category : Medical
ISBN : 9780444636690

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The Heart in Systemic Autoimmune Diseases by Fabiola Atzeni,Andrea Dorea,Mike Nurmohamed,Paolo Pauletto Pdf

The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics. Presents an impressive body of well ordered information on the topic of cardiovascular diseases and their relationship to autoimmune illness Highlights key references Summarizes the experience of a selected panel of distinguished physician-scientists who are actively involved in the field of cardiovascular disease and systemic autoimmunity

Mayo Clinic Gastroenterology and Hepatology Board Review

Stephen C. Hauser,Darrell S. Pardi,John J. Poterucha
Mayo Clinic Gastroenterology and Hepatology Board Review Book PDF

Author : Stephen C. Hauser,Darrell S. Pardi,John J. Poterucha
Publisher : CRC Press
Page : 496 pages
File Size : 46,8 Mb
Release : 2005-08-29
Category : Medical
ISBN : 9780203502747

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Mayo Clinic Gastroenterology and Hepatology Board Review by Stephen C. Hauser,Darrell S. Pardi,John J. Poterucha Pdf

Written in a quick-review format perfect for the busy student and clinician, this Second Edition stands as the most illustrative and in-depth guide available to prepare for the gastroenterology board and recertification exams. Supplying readers with an armamentarium of case-based presentations, 219 quality images, and more than 400 references for f

Polymyositis and Dermatomyositis

Marinos C Dalakas
Polymyositis and Dermatomyositis Book PDF

Author : Marinos C Dalakas
Publisher : Butterworth-Heinemann
Page : 360 pages
File Size : 42,5 Mb
Release : 2013-10-22
Category : Health & Fitness
ISBN : 9781483163048

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Polymyositis and Dermatomyositis by Marinos C Dalakas Pdf

Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.