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Mathematical Tools for Understanding Infectious Disease Dynamics by Odo Diekmann,Hans Heesterbeek,Tom Britton Pdf
This book explains how to translate biological assumptions into mathematics to construct useful and consistent models, and how to use the biological interpretation and mathematical reasoning to analyze these models. It shows how to relate models to data through statistical inference, and how to gain important insights into infectious disease dynamics by translating mathematical results back to biology.
Mathematical Understanding of Infectious Disease Dynamics by Stefan Ma,Yingcun Xia Pdf
An Original book with a comprehensive collection of many significant topics of the frontiers in applied presentation of many epidemic models with many real-life examples. presents an integration of interesting ideas from the well-mixed fields of statistics and mathematics. A valuable resource for researchers in wide range of disciplines to solve problems of practical interest.
Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats Publisher : National Academies Press Page : 444 pages File Size : 46,7 Mb Release : 2014-09-03 Category : Medical ISBN : 9780309305020
The Influence of Global Environmental Change on Infectious Disease Dynamics by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf
The twentieth century witnessed an era of unprecedented, large-scale, anthropogenic changes to the natural environment. Understanding how environmental factors directly and indirectly affect the emergence and spread of infectious disease has assumed global importance for life on this planet. While the causal links between environmental change and disease emergence are complex, progress in understanding these links, as well as how their impacts may vary across space and time, will require transdisciplinary, transnational, collaborative research. This research may draw upon the expertise, tools, and approaches from a variety of disciplines. Such research may inform improvements in global readiness and capacity for surveillance, detection, and response to emerging microbial threats to plant, animal, and human health. The Influence of Global Environmental Change on Infectious Disease Dynamics is the summary of a workshop hosted by the Institute of Medicine Forum on Microbial Threats in September 2013 to explore the scientific and policy implications of the impacts of global environmental change on infectious disease emergence, establishment, and spread. This report examines the observed and potential influence of environmental factors, acting both individually and in synergy, on infectious disease dynamics. The report considers a range of approaches to improve global readiness and capacity for surveillance, detection, and response to emerging microbial threats to plant, animal, and human health in the face of ongoing global environmental change.
The Population Dynamics of Infectious Diseases: Theory and Applications by Roy M. Anderson Pdf
Since the beginning of this century there has been a growing interest in the study of the epidemiology and population dynamics of infectious disease agents. Mathematical and statistical methods have played an important role in the development of this field and a large, and sophisticated, literature exists which is concerned with the theory of epidemiological processes in popu lations and the dynamics of epidemie and endemie disease phenomena. Much ofthis literature is, however, rather formal and abstract in character, and the field has tended to become rather detached from its empirical base. Relatively little of the literature, for example, deals with the practical issues which are of major concern to public health workers. Encouragingly, in recent years there are signs of an increased awareness amongst theoreticians of the need to confront predictions with observed epidemiological trends, and to pay elose attention to the biological details of the interaction between host and disease agent. This trend has in part been stimulated by the early work of Ross and Macdonald, on the transmission dynamics of tropical parasitic infections, but a further impetus has been the recent advances made by ecologists in blending theory and observation in the study of plant and animal populations.
This book is designed to be a practical study in infectious disease dynamics. The book offers an easy to follow implementation and analysis of mathematical epidemiology. The book focuses on recent case studies in order to explore various conceptual, mathematical, and statistical issues. The dynamics of infectious diseases shows a wide diversity of pattern. Some have locally persistent chains-of-transmission, others persist spatially in ‘consumer-resource metapopulations’. Some infections are prevalent among the young, some among the old and some are age-invariant. Temporally, some diseases have little variation in prevalence, some have predictable seasonal shifts and others exhibit violent epidemics that may be regular or irregular in their timing. Models and ‘models-with-data’ have proved invaluable for understanding and predicting this diversity, and thence help improve intervention and control. Using mathematical models to understand infectious disease dynamics has a very rich history in epidemiology. The field has seen broad expansions of theories as well as a surge in real-life application of mathematics to dynamics and control of infectious disease. The chapters of Epidemics: Models and Data using R have been organized in a reasonably logical way: Chapters 1-10 is a mix and match of models, data and statistics pertaining to local disease dynamics; Chapters 11-13 pertains to spatial and spatiotemporal dynamics; Chapter 14 highlights similarities between the dynamics of infectious disease and parasitoid-host dynamics; Finally, Chapters 15 and 16 overview additional statistical methodology useful in studies of infectious disease dynamics. This book can be used as a guide for working with data, models and ‘models-and-data’ to understand epidemics and infectious disease dynamics in space and time.
Author : Roy M. Anderson,Robert M. May Publisher : Oxford University Press Page : 772 pages File Size : 55,9 Mb Release : 1991 Category : Medical ISBN : 019854040X
Infectious Diseases of Humans by Roy M. Anderson,Robert M. May Pdf
This book deals with infectious diseases -- viral, bacterial, protozoan and helminth -- in terms of the dynamics of their interaction with host populations. The book combines mathematical models with extensive use of epidemiological and other data. This analytic framework is highly useful for the evaluation of public health strategies aimed at controlling or eradicating particular infections. Such a framework is increasingly important in light of the widespread concern for primary health care programs aimed at such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis, and the advent of AIDS/HIV and other emerging viruses. Throughout the book, the mathematics is used as a tool for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two parts, one dealing with microparasites (viruses, bacteria and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. The book synthesizes previous work in this rapidly growing field (much of which is scattered between the ecological and the medical literature) with a good deal of new material.
Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases by Dongmei Chen,Bernard Moulin,Jianhong Wu Pdf
Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.
Disease Dynamics by Alexander Asachenkov,Guri Marchuk,Ronald Mohler,Serge Zuev Pdf
This text discusses mathematical modelling, analysis and control of the immune system and disease dynamics. The purpose of the book is the practical application of mathematics to immunology and medicine in order to establish a basis for more effective treatment, to provide a tutorial systematic description of how the immune system controls diseases and to present several significant examples such as malignant tumour dynamics and control, and viral hepatitis.
Mathematical Studies on Human Disease Dynamics by Abba B. Gumel,Carlos Castillo-Chávez,Ronald E. Mickens,Dominic P. Clemence Pdf
This volume contains the proceedings of the AMS-SIAM-IMS Joint Summer Research Conference on Modeling the Dynamics of Human Diseases: Emerging Paradigms and Challenges, held in Snowbird, Utah, July 17-21, 2005. The goal of the conference was to bring together leading and upcoming researchers to discuss the latest advances and challenges associated with the modeling of the dynamics of emerging and re-emerging diseases, and to explore various control strategies. The articles included in this book are devoted to some of the significant recent advances, trends, and challenges associated with the mathematical modeling and analysis of the dynamics and control of some diseases of public health importance. In addition to illustrating many of the diverse prevailing epidemiological challenges, together with the diversity of mathematical approaches needed to address them, this book provides insights on a number of topical modeling issues such as the modeling and control of mosquito-borne diseases, respiratory diseases, animal diseases (such as foot-and-mouth disease), cancer and tumor growth modeling, influenza, HIV, HPV, rotavirus, etc. This book also touches upon other important topics such as the use of modeling i
National Research Council,Division on Earth and Life Studies,Board on Atmospheric Sciences and Climate,Committee on Climate, Ecosystems, Infectious Disease, and Human Health
Author : National Research Council,Division on Earth and Life Studies,Board on Atmospheric Sciences and Climate,Committee on Climate, Ecosystems, Infectious Disease, and Human Health Publisher : National Academies Press Page : 161 pages File Size : 45,8 Mb Release : 2001-06-29 Category : Science ISBN : 9780309072786
Under the Weather by National Research Council,Division on Earth and Life Studies,Board on Atmospheric Sciences and Climate,Committee on Climate, Ecosystems, Infectious Disease, and Human Health Pdf
Since the dawn of medical science, people have recognized connections between a change in the weather and the appearance of epidemic disease. With today's technology, some hope that it will be possible to build models for predicting the emergence and spread of many infectious diseases based on climate and weather forecasts. However, separating the effects of climate from other effects presents a tremendous scientific challenge. Can we use climate and weather forecasts to predict infectious disease outbreaks? Can the field of public health advance from "surveillance and response" to "prediction and prevention?" And perhaps the most important question of all: Can we predict how global warming will affect the emergence and transmission of infectious disease agents around the world? Under the Weather evaluates our current understanding of the linkages among climate, ecosystems, and infectious disease; it then goes a step further and outlines the research needed to improve our understanding of these linkages. The book also examines the potential for using climate forecasts and ecological observations to help predict infectious disease outbreaks, identifies the necessary components for an epidemic early warning system, and reviews lessons learned from the use of climate forecasts in other realms of human activity.
Vertically Transmitted Diseases by Stavros Busenberg,Kenneth Cooke Pdf
Infectious diseases are transmitted through various different mechanisms including person to person interactions, by insect vectors and via vertical transmission from a parent to an unborn offspring. The population dynamics of such disease transmission can be very complicated and the development of rational strategies for controlling and preventing the spread of these diseases requires careful modeling and analysis. The book describes current methods for formulating models and analyzing the dynamics of the propagation of diseases which include vertical transmission as one of the mechanisms for their spread. Generic models that describe broad classes of diseases as well as models that are tailored to the dynamics of a specific infection are formulated and analyzed. The effects of incubation periods, maturation delays, and age-structure, interactions between disease transmission and demographic changes, population crowding, spatial spread, chaotic dynamic behavior, seasonal periodicities and discrete time interval events are studied within the context of specific disease transmission models. No previous background in disease transmission modeling and analysis is assumedand the required biological concepts and mathematical methods are gradually introduced within the context of specific disease transmission models. Graphs are widely used to illustrate and explain the modeling assumptions and results. REMARKS: NOTE: the authors have supplied variants on the promotion text that are more suitable for promotionin different fields (by virtue of different emphasis in the content). They are not enclosed, but in the mathematics editorial.
Modeling and Dynamics of Infectious Diseases by Zhien Ma,Yicang Zhou,Jianhong Wu Pdf
This book provides a systematic introduction to the fundamental methods and techniques and the frontiers of ? along with many new ideas and results on ? infectious disease modeling, parameter estimation and transmission dynamics. It provides complementary approaches, from deterministic to statistical to network modeling; and it seeks viewpoints of the same issues from different angles, from mathematical modeling to statistical analysis to computer simulations and finally to concrete applications.
Mathematical Understanding of Infectious Disease Dynamics by Stefan Ma Pdf
The Institute for Mathematical Sciences at the National University of Singapore hosted a research program on Mathematical Modeling of Infectious Diseases: Dynamics and Control from 15 August to 9 October 2005. As part of the program, tutorials for graduate students and junior researchers were given by leading experts in the field.
Dean T. Jamison,Hellen Gelband,Susan Horton,Prabhat Jha,Charles N. Mock,Rachel Nugent
Author : Dean T. Jamison,Hellen Gelband,Susan Horton,Prabhat Jha,Charles N. Mock,Rachel Nugent Publisher : World Bank Publications Page : 426 pages File Size : 41,5 Mb Release : 2017-12-06 Category : Medical ISBN : 9781464805288
Disease Control Priorities, Third Edition (Volume 9) by Dean T. Jamison,Hellen Gelband,Susan Horton,Prabhat Jha,Charles N. Mock,Rachel Nugent Pdf
As the culminating volume in the DCP3 series, volume 9 will provide an overview of DCP3 findings and methods, a summary of messages and substantive lessons to be taken from DCP3, and a further discussion of cross-cutting and synthesizing topics across the first eight volumes. The introductory chapters (1-3) in this volume take as their starting point the elements of the Essential Packages presented in the overview chapters of each volume. First, the chapter on intersectoral policy priorities for health includes fiscal and intersectoral policies and assembles a subset of the population policies and applies strict criteria for a low-income setting in order to propose a "highest-priority" essential package. Second, the chapter on packages of care and delivery platforms for universal health coverage (UHC) includes health sector interventions, primarily clinical and public health services, and uses the same approach to propose a highest priority package of interventions and policies that meet similar criteria, provides cost estimates, and describes a pathway to UHC.