Disorders Of Human Growth

Author : Constantine A. Stratakis
Publisher : Academic Press
Page : 312 pages
File Size : 46,9 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9780128145388

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Gigantism and Acromegaly by Constantine A. Stratakis Pdf

Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism

Author : Jens O. L. Jørgensen,Jens Sandahl Christiansen
Publisher : Karger Medical and Scientific Publishers
Page : 241 pages
File Size : 50,5 Mb
Release : 2005-01-01
Category : Science
ISBN : 9783805579926

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Growth Hormone Deficiency in Adults by Jens O. L. Jørgensen,Jens Sandahl Christiansen Pdf

It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.

Author : Mary E. Williams
Publisher : Greenhaven Publishing LLC
Page : 168 pages
File Size : 44,9 Mb
Release : 2011-12-01
Category : Young Adult Nonfiction
ISBN : 9780737764901

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Growth Disorders by Mary E. Williams Pdf

Growth disorders prevent children from developing normal height, weight, sexual maturity or other features, at decreased or accelerated rates. Provide your readers with essential information on growth disorders. This book also serves as a historical survey, by providing information on the controversies surrounding its causes. Compelling first-person narratives by people coping with growth disorders give readers a first-hand experience. Patients, family members, or caregivers explain the condition from their own experience. The symptoms, causes, treatments, and potential cures are explained in detail. Essential to anyone trying to learn about diseases and conditions, the alternative treatments are explored. Each essay is carefully edited and presented with an introduction, so that they are accessible for student researchers and readers.

Author : Gilman D. Grave,Fernando G. Cassorla
Publisher : Charles C. Thomas Publisher
Page : 416 pages
File Size : 46,7 Mb
Release : 1988
Category : Medical
ISBN : UOM:39015014485547

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Disorders of Human Growth by Gilman D. Grave,Fernando G. Cassorla Pdf

Author : C. J. H. Kelnar
Publisher : Hodder Education
Page : 830 pages
File Size : 42,5 Mb
Release : 1998
Category : Medical
ISBN : UOM:39015040058508

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Growth Disorders by C. J. H. Kelnar Pdf

This book, written by internationally recognized experts in their respective disciplines, will provide comprehensive and up-to-date information about growth disorders for the practicing clinician who deals with children and adolescents. It will be a valuable reference source as well as a practical management guide for general and specialist paediatricians and endocrinologists. It would also be of interest to community and primary care health workers, as well as child and family psychiatrists.

Author : Chris Kelnar,Martin Savage,Paul Saenger,Chris Cowell
Publisher : CRC Press
Page : 728 pages
File Size : 47,9 Mb
Release : 2007-06-29
Category : Medical
ISBN : 9781444113730

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Growth Disorders 2E by Chris Kelnar,Martin Savage,Paul Saenger,Chris Cowell Pdf

Linear growth is a biological process of fundamental importance to the physical and psychological make-up of a child and adolescent but which can be subject to a number of interruptions and disorders. The management and treatment of patients with growth disorders constitues a major, and important, part of practice in clinical paediatrics, while in

Author : Roy G. Smith,Michael O. Thorner
Publisher : Springer Science & Business Media
Page : 345 pages
File Size : 48,8 Mb
Release : 2000-01-28
Category : Medical
ISBN : 9781592590155

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Human Growth Hormone by Roy G. Smith,Michael O. Thorner Pdf

In a state-of-the-art synthesis of basic science and clinical practice, Roy Smith and a distinguished panel of researchers and clinicians review GH regulation and its action at the molecular level, and describe the basis for GH deficiency and the use of GH as therapy in a variety of clinical situations. The clinical presentation moves beyond the treatment of GH-deficient children to include the genetics of GH-deficiency, GH-deficiency in adults, osteoporosis, Syndrome X, sleep quality, GH in AIDS patients, GHRH in clinical studies. Timely and innovative, Human Growth Hormone: Research and Clinical Practice will benefit both basic and clinical researchers, as well as those clinical endocrinologists who want to use growth hormone not only in treating children, but also in treating adult disorders, including those associated with metabolic disease.

Author : William Andrew Marshall
Publisher : Unknown
Page : 204 pages
File Size : 50,9 Mb
Release : 1977
Category : Family & Relationships
ISBN : UOM:39015000265945

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Human Growth and Its Disorders by William Andrew Marshall Pdf

Author : Anders Juul,Jens O. L. Jorgensen
Publisher : Cambridge University Press
Page : 536 pages
File Size : 41,9 Mb
Release : 2000-04-27
Category : Medical
ISBN : 0521641888

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Growth Hormone in Adults by Anders Juul,Jens O. L. Jorgensen Pdf

This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 43,5 Mb
Release : 2024-06-30
Category : Electronic
ISBN : OCLC:44210597

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Growth Disorders by Anonim Pdf

Presents information about human growth disorders, provided by the Human Growth Foundation (HGF), located in Falls Church, Virginia. Discusses human growth hormone (HGH) deficiency, Cushing's syndrome, hypothyroidism, nutritional short statute, Russell Silver syndrome, and other growth disorders.

Author : S. Raiti,R.A. Tolman
Publisher : Springer Science & Business Media
Page : 642 pages
File Size : 41,7 Mb
Release : 2013-11-09
Category : Medical
ISBN : 9781461572015

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Human Growth Hormone by S. Raiti,R.A. Tolman Pdf

It has been ten years since the National Hormone and Pituitary Program (then called the National Pituitary Agency) sponsored a symposium on human growth hormone (hGH). Numerous advances have occurred during this period. This book does not attempt to summarize past achievements. Rather, it deals with the contemporary issues in hGH research. A discussion of the present state of the art, of necessity, includes a review of the past. Some of the topics herein discussed include the following: 1. Growth hormone releasing factor (GRF). In 1973, the growth hormone inhibitory factor (somatostatin) had recently been discovered. The search for a releasing factor in humans led to its discovery not in the pituitary but in a pancreatic tumor that secreted growth hormone. The advances are discussed in this book. The current hope is that GRF will eventually become an effective therapeutic agent for idiopathic hypopituitarism in childhood and adolescence. 2. Biosynthesis of hGR by recombinant DNA technology. Current advances are discussed. Although hGH is not yet an approved drug, it will eventually become one. This will broaden our horizons in terms of hGH effectiveness in disorders other than hypopituitary dwarfism. The current experience with this type of hGH in both the Vnited States and Europe is reviewed by several authors.

Author : Edward C.C. Wong,Dennis J. Dietzen,Michael J. Bennett,Shannon Haymond
Publisher : Academic Press
Page : 1172 pages
File Size : 40,5 Mb
Release : 2021-05-13
Category : Science
ISBN : 9780128179635

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Biochemical and Molecular Basis of Pediatric Disease by Edward C.C. Wong,Dennis J. Dietzen,Michael J. Bennett,Shannon Haymond Pdf

Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. Provides a fully-updated resource with more color illustrations Focuses on the biochemical and molecular basis of disease as well as the analytical techniques Defines important differences in the pathophysiology of diseases, comparing childhood with adult

Author : Donald A. P. Bundy,Nilanthi de Silva,Susan Horton,Dean T. Jamison
Publisher : World Bank Publications
Page : 502 pages
File Size : 53,8 Mb
Release : 2017-11-20
Category : Medical
ISBN : 9781464804397

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Disease Control Priorities, Third Edition (Volume 8) by Donald A. P. Bundy,Nilanthi de Silva,Susan Horton,Dean T. Jamison Pdf

More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.

Author : Adair Stuart Mason
Publisher : Unknown
Page : 218 pages
File Size : 55,8 Mb
Release : 1972
Category : Science
ISBN : UOM:39015000265168

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Human Growth Hormone by Adair Stuart Mason Pdf

Human Growth Hormone is a compendium of papers that discusses all aspects of human growth hormone (HGH) relevant in the treatment of dwarfs who are HGH deficient. This book discusses the approach of growth hormone treatment including the preparation of the hormone, its effect and interactions with other hormones, the methods used to detect growth hormone in human plasma, as well as its clinical applications. One author discusses the preparation of human growth hormone, its storage, method of bioassay, and procedures for ampouling HGH for clinical use. A couple of authors review the metabolic a ...

Author : Laurie E. Cohen
Publisher : Springer
Page : 228 pages
File Size : 44,7 Mb
Release : 2016-07-04
Category : Medical
ISBN : 9783319280387

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Growth Hormone Deficiency by Laurie E. Cohen Pdf

Providing the most current information on the function of human growth hormone (GH) and the consequences of its deficiency, this practical yet comprehensive text is divided into three sections. Part one describes the mechanisms of GH secretion and action, including the physiology of GH and its regulation by sex steroids and thyroid hormones, the effects of both under nutrition and obesity on GH secretion, and the metabolic effects of human recombinant GH therapy. The second section covers diagnostic strategies and tests for GH deficiency in both children and adults, including MRI of the pituitary. The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist.