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Disruption Of Apoptotic Signaling Pathways During Glucocorticoid Induced Survival Of Human Neutrophils Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Disruption Of Apoptotic Signaling Pathways During Glucocorticoid Induced Survival Of Human Neutrophils book. This book definitely worth reading, it is an incredibly well-written.
Author : Joseph W. Frentzel
Publisher : Unknown
Page : 518 pages
File Size : 48,5 Mb
Release : 2008
Category : Apoptosis
ISBN : MSU:31293029567090
Author : Anonim
Publisher : Unknown
Page : 1840 pages
File Size : 53,7 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864682
Author : Anonim
Publisher : Unknown
Page : 2430 pages
File Size : 53,8 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P00992564E
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : Ajay Vora
Publisher : Springer
Page : 342 pages
File Size : 41,6 Mb
Release : 2017-04-21
Category : Medical
ISBN : 9783319397085
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author : Jen-Chywan Wang,Charles Harris
Publisher : Springer
Page : 385 pages
File Size : 40,5 Mb
Release : 2015-07-27
Category : Science
ISBN : 9781493928958
This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
Author : Luis Enrique Muñoz,Christian Berens,Kirsten Lauber
Publisher : Frontiers Media SA
Page : 75 pages
File Size : 45,9 Mb
Release : 2015-08-17
Category : Immunologic diseases. Allergy
ISBN : 9782889196012
In multicellular organisms, states with a high degree of tissue turnover like embryogenesis, development, and adult tissue homeostasis need an instantaneous, tightly regulated and immunologically silent clearance of these dying cells to ensure appropriate development of the embryo and adult tissue remodelling. The proper and swift clearance of apoptotic cells is essential to prevent cellular leakage of damage associated molecular patterns (DAMPs) which would lead to the stimulation of inflammatory cytokine responses. In addition to the clearance of apoptotic cells (efferocytosis), backup mechanisms are required to cope with DAMPs (HMGB-1, DNA, RNA, S100 molecules, ATP and adenosine) and other intracellular material (uric acid, intracellular proteins and their aggregates) released from cells, that were not properly cleared and have entered the stage of secondary necrosis. Furthermore, under certain pathologic conditions (e.g. gout, cancer, diabetes) non-apoptotic cell death may transiently occur (NETosis, necroptosis, pyroptosis) which generates material that also has to be cleared to avoid overloading tissues with non-functional cellular waste. Efficient efferocytosis is therefore indispensable for normal tissue turnover and homeostasis. The characterization of various signalling pathways that regulate this complex and evolutionary conserved process has shed light on new pathogenetic mechanisms of many diseases. Impaired clearance promotes initiation of autoimmunity as well as the perpetuation of chronic inflammation, but may also foster anti-tumor immunity under certain microenvironmental conditions. Immunological tolerance is continuously being challenged by the presence of post-apoptotic remnants in peripheral lymphoid tissues. Besides the autoimmune phenotype of chronic inflammatory rheumatoid disorders a plethora of pathologies have been associated with defects in genes involved in clearance, e.g. atherosclerosis, cancer, gout, diabetes, some forms of blindness, neuropathy, schizophrenia and Alzheimer’s disease. The main goal of this research topic is to collect contributions from various disciplines committed to studying pathogenetic mechanisms of the aforementioned disorders and dealing with alterations in the clearance of dying and dead cells, their remnants, and their constituents that leak out after membrane rupture. Integrating the combined collection of knowledge on efferocytosis and clearance of dead cells and their derived waste from different fields of research in physiology and pathophysiology could improve the molecular understanding of these increasingly prevalent diseases and may ultimately result in new therapeutic strategies.
Author : Stephan R. Targan,Fergus Shanahan,Loren C. Karp
Publisher : John Wiley & Sons
Page : 1429 pages
File Size : 43,5 Mb
Release : 2011-08-24
Category : Medical
ISBN : 9781444359114
This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.
Author : James J. Lee,Helene F. Rosenberg
Publisher : Academic Press
Page : 679 pages
File Size : 55,8 Mb
Release : 2012-11-02
Category : Health & Fitness
ISBN : 9780123943859
Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.
Author : Bharat B. Aggarwal,Bokyung Sung,Subash Chandra Gupta
Publisher : Springer
Page : 489 pages
File Size : 40,6 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9783034808378
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author : John L. Marshall
Publisher : Springer
Page : 0 pages
File Size : 55,5 Mb
Release : 2017-06-17
Category : Medical
ISBN : 1441907165
In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated by the discovery and approval of new medicines which have been approved for the treatment of cancer. On the heels of these successes, innumerable new targets and new potential therapeutics are being developed by many different groups including government agencies, pharmaceutical companies, biotechnology companies, academic institutions, and individual investigators. Understanding the expanding "universe" of cancer therapies is therefore becoming impossible and no single source exists which serves as a reference for the involved parties. Further, the interested parties have vastly different areas of expertise, from focused laboratory based science, to clinical research, to corporate and regulatory oversight. The text would be updated every two years, more often depending on pace of change, interest and sales. While useful online, this reference book would likely be kept in hard copy as well.
Author : Emira Ayroldi,Claude Libert,Alexandra K. Kiemer
Publisher : Frontiers Media SA
Page : 233 pages
File Size : 45,5 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9782889717439
Author : Edwin A. Deitch,J. L. Vincent,Alastair Windsor
Publisher : Saunders
Page : 524 pages
File Size : 45,6 Mb
Release : 2002
Category : Multiple organ failure
ISBN : CHI:65664902
This is the definitive, gold-standard text on sepsis and multiple-organ dysfunction. It is comprehensive and thoroughly referenced: the one text in which all current knowledge on this important topic is brought together. The book is written by a team of international contributors, overseen by an internationally acclaimed editorial team.
Author : Liqing Zang,Norihiro Nishimura,Vincenzo Torraca,Yasuhito Shimada
Publisher : Frontiers Media SA
Page : 496 pages
File Size : 52,9 Mb
Release : 2022-04-04
Category : Science
ISBN : 9782889748327
Author : Anonim
Publisher : Unknown
Page : 240 pages
File Size : 53,5 Mb
Release : 1999
Category : Acetylcholine
ISBN : IND:30000143535791
Author : Anonim
Publisher : Unknown
Page : 240 pages
File Size : 44,7 Mb
Release : 1993
Category : Environmental health
ISBN : UCR:31210012223754
