Download Full eBooks in PDF
Dna Topology Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Dna Topology book. This book definitely worth reading, it is an incredibly well-written.
Author : Andrew D. Bates,Anthony Maxwell
Publisher : Oxford University Press, USA
Page : 224 pages
File Size : 43,7 Mb
Release : 2005
Category : Science
ISBN : 019856709X
"A key aspect of DNA is its ability to form a variety of structures, this book explains the origins and importance of such structures"--Provided by publisher.
Author : Michael I. Monastyrsky
Publisher : Springer Science & Business Media
Page : 238 pages
File Size : 49,7 Mb
Release : 2006-10-26
Category : Science
ISBN : 9783540498582
Providing a course of modern topology intended for biologists and physicists, this book presents a class of results in molecular biology for which topological methods and ideas are important. These include: the large-scale conformation properties of DNA; computational methods; the structure of proteins; and other problems in molecular biology.
Author : Craig John Benham,Stephen Harvey,Wilma K. Olson,De Witt Sumners,David Swigon
Publisher : Springer Science & Business Media
Page : 356 pages
File Size : 41,6 Mb
Release : 2009-07-30
Category : Medical
ISBN : 9781441906700
Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.
Author : De Witt L. Sumners,Nicholas R. Cozzarelli
Publisher : American Mathematical Soc.
Page : 266 pages
File Size : 53,5 Mb
Release : 1992
Category : Mathematics
ISBN : 0821855026
Geometry and topology are subjects generally considered to be "pure" mathematics. Recently, however, some of the methods and results in these two areas have found new utility in both wet-lab science (biology and chemistry) and theoretical physics. Conversely, science is influencing mathematics, from posing questions that call for the construction of mathematical models to exporting theoretical methods of attack on long-standing problems of mathematical interest. Based on an AMS Short Course held in January 1992, this book contains six introductory articles on these intriguing new connections. There are articles by a chemist and a biologist about mathematics, and four articles by mathematicians writing about science and mathematics involved. Because this book communicates the excitement and utility of mathematics research at an elementary level, it is an excellent textbook in an advanced undergraduate mathematics course.
Author : Alexander Vologodskii
Publisher : CRC Press
Page : 196 pages
File Size : 50,9 Mb
Release : 1992-06-16
Category : Medical
ISBN : 0849342287
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.
Author : Danail Bonchev,Dennis H Rouvray
Publisher : CRC Press
Page : 392 pages
File Size : 49,6 Mb
Release : 2000-07-06
Category : Science
ISBN : 9056992406
Topology has been extensively applied in the study of chemically linked and knotted structures, and also in the study of many biologically significant molecules such as proteins and DNA. These are the themes that are addressed in this volume of the Mathematical Chemistry series. The topological chirality of knotted and linked molecular species and the invariants that may characterize them are explored in detail.
Author : Nicholas R. Cozzarelli,James C. Wang
Publisher : Unknown
Page : 504 pages
File Size : 51,6 Mb
Release : 1990
Category : Science
ISBN : UOM:39015018988884
Author : Colin C. Adams,Cameron McA. Gordon,Vaughan F.R. Jones,Louis H. Kauffman,Sofia Lambropoulou,Kenneth C. Millett,Jozef H. Przytycki,Renzo Ricca,Radmila Sazdanovic
Publisher : Springer
Page : 476 pages
File Size : 55,7 Mb
Release : 2019-06-26
Category : Mathematics
ISBN : 9783030160319
This proceedings volume presents a diverse collection of high-quality, state-of-the-art research and survey articles written by top experts in low-dimensional topology and its applications. The focal topics include the wide range of historical and contemporary invariants of knots and links and related topics such as three- and four-dimensional manifolds, braids, virtual knot theory, quantum invariants, braids, skein modules and knot algebras, link homology, quandles and their homology; hyperbolic knots and geometric structures of three-dimensional manifolds; the mechanism of topological surgery in physical processes, knots in Nature in the sense of physical knots with applications to polymers, DNA enzyme mechanisms, and protein structure and function. The contents is based on contributions presented at the International Conference on Knots, Low-Dimensional Topology and Applications – Knots in Hellas 2016, which was held at the International Olympic Academy in Greece in July 2016. The goal of the international conference was to promote the exchange of methods and ideas across disciplines and generations, from graduate students to senior researchers, and to explore fundamental research problems in the broad fields of knot theory and low-dimensional topology. This book will benefit all researchers who wish to take their research in new directions, to learn about new tools and methods, and to discover relevant and recent literature for future study.
Author : Yicheng Cao
Publisher : Unknown
Page : 304 pages
File Size : 54,7 Mb
Release : 1993
Category : Electronic
ISBN : UCAL:X53521
Author : Vicki Gee Norton
Publisher : Unknown
Page : 306 pages
File Size : 42,5 Mb
Release : 1990
Category : Electronic
ISBN : UCAL:X42629
Author : Peter B. Becker
Publisher : Springer Science & Business Media
Page : 525 pages
File Size : 53,8 Mb
Release : 2008-02-03
Category : Science
ISBN : 9781592596812
More than 40 years after the discovery of the nucleosome as the fun- mental unit of chromatin, the multifaceted problem of how variations in ch- matin structure affect the activity of the eukaryotic genome has not been solved. However, during the past few years research on chromatin structure and fu- tion has gained considerable momentum, and impressive progress has been made at the level of concept development as well as filling in crucial detail. The structure of the nucleosome has been visualized at unprecedented reso- tion. Powerful multisubunit enzymes have been identified that alter histone/ DNA interactions in ways that expose regulatory sequences to factors initi- ing and regulating such nuclear processes as transcription. Though the imp- tance of posttranslational modifications of histones, notably their acetylation, has long been known, the finding that a number of bona fide regulators increase transcription by acetylating nucleosomes has lent new support to the old idea that the process of gene regulation is intimately related to the nature of the chromatin environment. A wealth of nonhistone proteins contribute to a continuum of structures with distinct biochemical properties and varying degrees of DNA condensation. Perhaps the most important conclusion from a large number of studies is a fresh appreciation of the dynamic nature of chromatin structure, the built-in flexibility providing the basis for regulation.
Author : Alexander Vologodskii
Publisher : CRC Press
Page : 246 pages
File Size : 55,8 Mb
Release : 2017-11-22
Category : Medical
ISBN : 9781351355827
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.
Author : Christophe Lavelle,Jean-Marc Victor
Publisher : Academic Press
Page : 618 pages
File Size : 50,6 Mb
Release : 2017-10-27
Category : Medical
ISBN : 9780128035030
Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds
Author : National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on the Mathematical Sciences in Genome and Protein Structure Research
Publisher : National Academies Press
Page : 300 pages
File Size : 42,7 Mb
Release : 1995-04-06
Category : Science
ISBN : 9780309048866
As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have played an increasingly important roleâ€"in genome mapping, population genetics, and even the controversial search for "Eve," hypothetical mother of the human race. In this first-ever survey of the partnership between the two fields, leading experts look at how mathematical research and methods have made possible important discoveries in biology. The volume explores how differential geometry, topology, and differential mechanics have allowed researchers to "wind" and "unwind" DNA's double helix to understand the phenomenon of supercoiling. It explains how mathematical tools are revealing the workings of enzymes and proteins. And it describes how mathematicians are detecting echoes from the origin of life by applying stochastic and statistical theory to the study of DNA sequences. This informative and motivational book will be of interest to researchers, research administrators, and educators and students in mathematics, computer sciences, and biology.
Author : Mary-Ann Bjornsti,Neil Osheroff
Publisher : Springer Science & Business Media
Page : 352 pages
File Size : 45,7 Mb
Release : 1999-03-23
Category : Medical
ISBN : WISC:89063849103
DNA Topoisomerase Protocols, I: DNA Topology and Enzymes brings together an unprecedented collection of cutting-edge experimental protocols for investigating DNA structure, topology, and DNA topoisomerase function. Described by expert experimentalists who have perfected the techniques, these unfailingly reproducible methods utilize new approaches to study changes in DNA topology (linking number, knotting, catenation, and relaxation) and DNA structure (bending), as well as to assess chromosome structure through FLP-mediated recombination and to analyze bacterial nucleoid structure. State-of-the-art protocols also detail the expression and purification of bacterial, viral, and eukaryotic DNA topoisomerases from a variety of sources, including baculovirus, and bacterial, yeast and mammalian expression systems. A companion volume, DNA Topoisomerase Protocols, v. 2: Enzymology and Drugs, provides detailed protocols to study the catalytic activities of DNA topoisomerases, as well as their specific interactions with topoisomerase-targeted antitumor and antibacterial drugs. DNA Topoisomerase Protocols, I: DNA Topology and Enzymes will be of immense value to the many basic scientists and clinicians who want better to understand and to exploit proficiently the wealth of recent discoveries about chromatin structure and its relation to gene expression, about DNA topoisomerases as the targets of antitumor and antibacterial agents, and about DNA repair.
