Author : Anonim
Publisher : Unknown
Page : 424 pages
File Size : 40,5 Mb
Release : 1994
Category : Drugs
ISBN : CHI:42764490
Drug Development in the Nineties
Anonim
Drug Development In The Nineties
Drug Development In The Nineties Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Drug Development In The Nineties book. This book definitely worth reading, it is an incredibly well-written.
Cancer Drug Discovery for the 1990s
Bruce Chabner
Author : Bruce Chabner
Publisher : Unknown
Page : 16 pages
File Size : 47,6 Mb
Release : 1988
Category : Cancer
ISBN : MINN:319510029627581
Cancer Drug Discovery for the 1990s by Bruce Chabner Pdf
Drugs in the 1990s, New Perils, New Promise
United States. Congress. Senate. Committee on the Judiciary
Author : United States. Congress. Senate. Committee on the Judiciary
Publisher : Unknown
Page : 258 pages
File Size : 48,6 Mb
Release : 1991
Category : Drug abuse
ISBN : UOM:39015042702103
Drugs in the 1990s, New Perils, New Promise by United States. Congress. Senate. Committee on the Judiciary Pdf
Blood-Brain Barrier in Drug Discovery
Li Di,Edward H. Kerns
Author : Li Di,Edward H. Kerns
Publisher : John Wiley & Sons
Page : 604 pages
File Size : 40,5 Mb
Release : 2015-02-02
Category : Medical
ISBN : 9781118788356
Blood-Brain Barrier in Drug Discovery by Li Di,Edward H. Kerns Pdf
Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market
Emerging Targets in Antibacterial and Antifungal Chemotherapy
Joyce Sutcliffe,Nafsika Georgopapadakou
Author : Joyce Sutcliffe,Nafsika Georgopapadakou
Publisher : Springer Science & Business Media
Page : 619 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461532743
Emerging Targets in Antibacterial and Antifungal Chemotherapy by Joyce Sutcliffe,Nafsika Georgopapadakou Pdf
Emerging Targets in Antibacterial and Antifungal Chemotherapy offers constructive ideas to researchers that could lead to the discovery of entirely new classes of drugs. The authors emphasize new topics rather than review work on known antibacterials and antifungals, and identify new targets--either the rate-limiting component of a biochemical pathway or a component of the pathway that is susceptible to a ``screening'' or ``rational drug design'' approach. Each chapter reviews the biochemical pathway and its place in the cellular scheme in order to place the target in perspective. The authors, a mixture of academic researchers and drug-discovery investigators in pharmaceutical companies, also extend these theoretical concerns into practical applications and suggest useful screening methodologies. The importance of this subject area is demonstrated by the increasing number of papers in the literature that point to potential targets and screening methodologies for new antibacterials. This book also deals with antifungals, investigating the inherent limitations in existing antifungals (many of which are extremely toxic or have only limited efficacy), and pointing to major developments in the discovery of novel antifungals. Emerging Targets in Antibacterial and Antifungal Chemotherapy will be of interest to professional microbiologists, biochemists, and cell biologists in both academic and industrial laboratories.
Modern Methods of Clinical Investigation
Institute of Medicine,Committee on Technological Innovation in Medicine
Author : Institute of Medicine,Committee on Technological Innovation in Medicine
Publisher : National Academies Press
Page : 241 pages
File Size : 54,8 Mb
Release : 1990-02-01
Category : Medical
ISBN : 9780309042864
Modern Methods of Clinical Investigation by Institute of Medicine,Committee on Technological Innovation in Medicine Pdf
The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.
High-Speed Management and Organizational Communication in the 1990s
Sarah Sanderson King,Donald P. Cushman
Author : Sarah Sanderson King,Donald P. Cushman
Publisher : State University of New York Press
Page : 330 pages
File Size : 54,8 Mb
Release : 1994-02-24
Category : Business & Economics
ISBN : 9781438409085
High-Speed Management and Organizational Communication in the 1990s by Sarah Sanderson King,Donald P. Cushman Pdf
High-Speed Management and Organizational Communication in the 1990s provides a unique, systematic, and practical treatment of the role communication plays in the new organizations. It treats organizational integration, coordination, and control as central communication processes and explores their transformation of traditional organizational topics such as leadership, corporate culture, teamwork, and continuous improvement programs. The central thesis of this analysis is that increasing the speed with which products get to market helps to make an organization more productive, develop better quality products, become more responsive to customer needs, and generate more profits for investors. Why and how this takes place as well as the central role communication plays in the process is treated here in detail.
Pharmacology for Chemists
Raymond Hill,Terry Kenakin,Tom Blackburn
Author : Raymond Hill,Terry Kenakin,Tom Blackburn
Publisher : Royal Society of Chemistry
Page : 538 pages
File Size : 54,7 Mb
Release : 2017-10-30
Category : Medical
ISBN : 9781782621423
Pharmacology for Chemists by Raymond Hill,Terry Kenakin,Tom Blackburn Pdf
This textbook explains the key issues in pharmacology to chemists interested in or planning to work in drug discovery.
The Baltic Sea Region
Witold Maciejewski
Author : Witold Maciejewski
Publisher : Baltic University Press
Page : 686 pages
File Size : 44,7 Mb
Release : 2002
Category : Baltic Sea Region
ISBN : 9789197357982
The Baltic Sea Region by Witold Maciejewski Pdf
Guidebook on Molecular Modeling in Drug Design
N. Claude Cohen
Author : N. Claude Cohen
Publisher : Elsevier
Page : 376 pages
File Size : 52,6 Mb
Release : 1996-05-16
Category : Science
ISBN : 9780080532332
Guidebook on Molecular Modeling in Drug Design by N. Claude Cohen Pdf
Specially designed computer software is revolutionizing procedures for structured or rational drug design and discovery. The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis ofmolecular structure and the correlation of these structures with pharmacological reactions. Intended as an introductory guide for advanced students and professionals with an interest in computer-assisted modeling for drug design and discovery, this bookwill also be of interest to medicinal and organic chemists, pharmaceutical researchers, pharmacologists, and biochemists who want to gain further insight into this rapidly advancing field. Molecular modeling is assuming an important role in the understanding of three-dimensional aspects in the specificity of drug-receptor interactions at the molecular level. This research area has become a well-established discipline in pharmaceutical research. It has created unprecedented opportunities in assisting medicinal chemists in the design of new therapeutic agents. Advances made in computer hardware and in theoretical medicinal chemistry have brought high-performance computing and graphics tools within reach of most academic and industrial laboratories, facilitating the development of useful approaches to rational drug design. The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis of the molecular structure of biological molecules and drugs and the correlation of these structures with pharmacological actions. Intended as a guide for advanced students and professionals with an interest in computer-assisted modeling for drug design and discovery, this book will also be of interest to medicinal and organic chemists, pharmaceutical researchers, pharmacologists, and biochemists who want to gain further insight into this rapidly advancing field.
Monthly Catalogue, United States Public Documents
Anonim
Author : Anonim
Publisher : Unknown
Page : 1480 pages
File Size : 47,9 Mb
Release : 1990
Category : Government publications
ISBN : UIUC:30112063914524
Monthly Catalogue, United States Public Documents by Anonim Pdf
Monthly Catalog of United States Government Publications
Anonim
Author : Anonim
Publisher : Unknown
Page : 1482 pages
File Size : 43,7 Mb
Release : 1990
Category : Government publications
ISBN : OSU:32437010625644
Monthly Catalog of United States Government Publications by Anonim Pdf
Rare Diseases and Orphan Products
Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
Publisher : National Academies Press
Page : 442 pages
File Size : 53,5 Mb
Release : 2011-04-03
Category : Medical
ISBN : 9780309158060
Rare Diseases and Orphan Products by Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development Pdf
Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.
Pharmaceutical Medicine and Translational Clinical Research
Divya Vohora,Gursharan Singh
Author : Divya Vohora,Gursharan Singh
Publisher : Academic Press
Page : 526 pages
File Size : 44,6 Mb
Release : 2017-11-14
Category : Medical
ISBN : 9780128020982
Pharmaceutical Medicine and Translational Clinical Research by Divya Vohora,Gursharan Singh Pdf
Pharmaceutical Medicine and Translational Clinical Research covers clinical testing of medicines and the translation of pharmaceutical drug research into new medicines, also focusing on the need to understand the safety profile of medicine and the benefit-risk balance. Pharmacoeconomics and the social impact of healthcare on patients and public health are also featured. It is written in a clear and straightforward manner to enable rapid review and assimilation of complex information and contains reader-friendly features. As a greater understanding of these aspects is critical for students in the areas of pharmaceutical medicine, clinical research, pharmacology and pharmacy, as well as professionals working in the pharmaceutical industry, this book is an ideal resource. Includes detailed coverage of current trends and key topics in pharmaceutical medicine, including biosimilars, biobetters, super generics, and Provides a comprehensive look at current and important aspects of the science and regulation of drug and biologics discovery
Quality of Life Assessment: Key Issues in the 1990s
S.R. Walker,Rachel M. Rosser
Author : S.R. Walker,Rachel M. Rosser
Publisher : Springer Science & Business Media
Page : 491 pages
File Size : 40,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401129886
Quality of Life Assessment: Key Issues in the 1990s by S.R. Walker,Rachel M. Rosser Pdf
It was over five years ago that the Centre for Medicines Research organized a workshop entitled "Quality of Life: Assessment and Application". This workshop brought together a unique group of participants, some of whom had been involved in studies on quality of life for well over a decade, whilst others were meeting the subject for the first time. This blend of experienced researchers and enthusiastic newcomers was a great stimulus to the discus sions which followed individual presentations as well as that resulting from the study groups. In the ensuing publication, a balance was sought between a consideration of the complex principles underlying the assessment of quality of life and the application of such assessments to specific clinical conditions which necessitated this approach. The organization in 1991 of a second workshop entitled "Quality of Life Assessment: Key Issues in the 1990s" resulted in a further consideration of the quality of life philosophy, concepts and key instruments together with an update on assessing quality of life in a number of major disease areas. Of particular importance was an examination of various viewpoints concerned with ethical questions and their implications, and quality oflife from industry, regulatory and health care purchasers' perspectives. As a result of this second workshop, the editors of the original book referred to above decided to produce a second edition with a number of updates and additional chapters.