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Drugs and Bugs - a little book about medicines by Fredrik Brouneus,Nina Erixon-Lindroth Pdf
In Drugs and Bugs you will read about everything that is exciting about medicines - from crocodile poo and hippo fat in ancient Egypt, to today's injections and tablets. You will find out how vaccines work, why antibiotics are useless against the common cold and how scientists go about inventing new medicines. You will also learn about viruses, bacteria, fungi and parasites, how they attack the body and how we defend ourselves - both with and without medicines. And lots more! Drugs and Bugs is written by Fredrik Brouneus, pharmacist and writer. The book is richly illustrated by Nina Erixon-Lindroth, illustrator and neuroscientist.
Author : Robert A. Britton,Patrice D. Cani Publisher : John Wiley & Sons Page : 514 pages File Size : 55,8 Mb Release : 2020-07-02 Category : Medical ISBN : 9781555819705
Bugs as Drugs by Robert A. Britton,Patrice D. Cani Pdf
Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.
What is the number one killer in the United States? Medical treatment. Western medicine has cures for surprisingly few diseases and actually causes illness with its drugs for every disease approach. Infectious diseases are making a comeback due to the overuse of antibiotics and our war on germs. We've seen an exponential rise in autism while vaccinating more than any other country. According to the Journal of the American Medical Association, properly prescribed medication is the fourth leading cause of death, hospitals are the third, and medical doctors kill more than all other forms of accidental death combined. This first book in the Why We're Sick series exposes the myths, lies, greed, and just plain bungling that is the untold story of Western medicine. Deeply researched, deadly serious, yet often humorous and irreverent, no other work so thoroughly explains how we got into this mess and what we can do to be truly healthy.
The Drugs Don't Work by Professor Dame Sally Davies,Jonathan Grant,Mike Catchpole Pdf
The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for England 'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren. Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food. No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall. Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College. Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics. Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.
No-Nonsense Guide to Antibiotics by Moira Dolan Pdf
Antibiotics can be lifesaving, but they are so often prescribed without good reason that they generate more drug side effects than any other class of medicines. On a personal level, antibiotics can cause mild to deathly side effects. Antibiotic overuse in the larger society has forced the widespread growth of drug resistant bugs, causing a global health crisis according to the World Health Organization. In this latest in the series of No-Nonsense Guides, Dr. Dolan describes a rational approach to appropriate antibiotic use or avoidance. This handy reference for many of the most common symptoms and illnesses discusses antibiotic characteristics and side effects in easy-to-understand language. As with Dr. Dolan's other SmartMEDinfo No-Nonsense Guides, this book is not 'anti-drug' but rather 'pro-informed consent' with the goal of empowering consumers to consider the risks and benefits of prescriptions for themselves.
Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.
Chinese Traditional Healing (3 vols) by Paul Unschuld,Jinsheng ZHENG Pdf
Research on past knowledge, practices, personnel and institutions of Chinese health care has focussed on printed text for many decades. The Berlin collections of handwritten Chinese volumes on health and healing from the past 400 years provide a hitherto unprecedented access to a wide range of data. They extend the reach of medical historiography beyond the literature written by and for a small social elite to the reality of health care as practiced by private households, lay healers, pharmacists, professional doctors, magicians, itinerant healers and others. The nearly 900 volumes surveyed here for the first time demonstrate the heterogeneity of Chinese traditional healing. They evidence the continuation of millennia-old therapeutic approaches long discarded by the elite, and they show continuous adaptation to more recent trends.
Bombs, Bugs, Drugs, and Thugs by Loch K. Johnson Pdf
Johnson, author of the acclaimed Secret Agencies and ""an experienced overseer of intelligence"" (Foreign Affairs), here examines the present state and future challenges of American strategic intelligence.
International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?
Applied Pharmacology E-Book by Stan Bardal,Jason Waechter,Doug Martin Pdf
Applied Pharmacology provides the essential details that are required for a solid understanding of pharmacology: how the drugs work, why side effects occur, and how the drugs are used clinically. Drs. Stan Bardal, Jason Waechter, and Doug Martin integrate the experience of the pharmacologist and the physician for a clinical focus that ensures a complete understanding of pharmacology...in print and online. Find information quickly and compare and contrast drugs easily thanks to a clear and consistent format without extraneous material. Apply basic pharmacology to clinical situations through integrated text. Enhance your learning with "For Your Information" sections detailing history and anecdotes for many agents within a given drug class. Find a wealth of additional resources online at www.studentconsult.com. Learn the essential details of pharmacology and enhance your understanding through an entirely new, fantastic art program.
The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.
Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century
Author : Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century Publisher : National Academies Press Page : 397 pages File Size : 45,7 Mb Release : 2003-08-25 Category : Medical ISBN : 9780309185547
Microbial Threats to Health by Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century Pdf
Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
Textbook of Adult Emergency Medicine E-Book by Peter Cameron,Mark Little,Biswadev Mitra,Conor Deasy Pdf
Since the first edition of Textbook of Adult Emergency Medicine was published twenty years ago, there has been enormous change in the way emergency care is delivered. This has occurred both in countries where emergency medicine was originally developed and in those where its application was limited because of cost. Emergency medicine is now perceived as the cornerstone of response to acute illness regardless of resources. This fully revised Fifth Edition provides clear and consistent coverage of this constantly evolving specialty. Building on the success of previous editions it covers all the major topics relevant to the practice of emergency medicine. The book will prove invaluable to professionals working in this setting – including nurse specialists and paramedics – who require concise, highly practical guidance, incorporating the latest best practice and evidence-based guidelines. This edition comes with an enhanced electronic version with video and self-assessment content, providing a richer learning experience and making rapid reference easier than ever before, anytime, anywhere. A comprehensive textbook of adult emergency medicine for trainee doctors - covers all the problems likely to present to a trainee in the emergency department. Chapters are highly readable and concise – boxes summarise chapter key points and highlight controversial areas of treatment. The content is highly practical, clinically orientated and thoroughly updated in all the core subjects There have been major updates in topics such as airway, shock and sepsis where guidelines have changed rapidly. The imaging chapters have also evolved with changing practice and improved technology, to be concordant with evidence on the importance of image interpretation by emergency clinicians. There are major sections on other skills and issues of key importance to today’s advanced emergency medicine practitioner, such as staffing, overcrowding, triage, patient safety and quality measures. In addition, difficult topics such as death and dying, the challenging patient, ethics, giving evidence and domestic violence are covered. Governance, training, research and organisational subjects such as disaster planning and response, humanitarian emergencies and refugee medicine are included to give the reader a framework to understand the complexity of managing major emergency systems of care.
