Early Markers In Parkinson S And Alzheimer S Diseases

Author : Philippe Dostert,Peter Riederer,Margherita Strolin Benedetti,Romeo Roncucci
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709190982

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Early Markers in Parkinson’s and Alzheimer’s Diseases by Philippe Dostert,Peter Riederer,Margherita Strolin Benedetti,Romeo Roncucci Pdf

The aim of Early Markers in Parkinson's and Alzheimer's Diseases is to provide the reader with updated data on various approaches whose investigation and development could contribute to the discovery of early diag- nostic markers of these two degenerative diseases. Concerning Parkinson's disease, some of the topics dealt with in the book will help update the information previously reported in Early Diagnosis and Preventive Therapy in Parkinson's Disease. Concerning Alzheimer's disease, the scope and limitations of electrophysiological and brain imaging techniques with regards to early detection of the disease are documented. Various biochemical parameters, such as brain energy metabolism, levels of choline, and platelet monoamine oxidase activity are envisaged as some of the starting points for the discovery of early diagnostic markers of Alzheimer's disease.

Author : P. Dostert
Publisher : Springer
Page : 344 pages
File Size : 41,5 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015022027695

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Early Markers in Parkinson's and Alzheimer's Diseases by P. Dostert Pdf

The aim of Early Markers in Parkinson's and Alzheimer's Diseases is to provide the reader with updated data on various approaches whose investigation and development could contribute to the discovery of early diag- nostic markers of these two degenerative diseases. Concerning Parkinson's disease, some of the topics dealt with in the book will help update the information previously reported in Early Diagnosis and Preventive Therapy in Parkinson's Disease. Concerning Alzheimer's disease, the scope and limitations of electrophysiological and brain imaging techniques with regards to early detection of the disease are documented. Various biochemical parameters, such as brain energy metabolism, levels of choline, and platelet monoamine oxidase activity are envisaged as some of the starting points for the discovery of early diagnostic markers of Alzheimer's disease.

Author : Leonard F. M. Scinto,Kirk R. Daffner
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 52,9 Mb
Release : 2000-02-09
Category : Medical
ISBN : 9781592590056

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Early Diagnosis of Alzheimer’s Disease by Leonard F. M. Scinto,Kirk R. Daffner Pdf

Drs. Leonard Scinto and Kirk Daffner provide a comprehensive survey of new diagnostic approaches to Alzheimer's disease. The authoritative contributors critically survey the most promising current research on early diagnostic markers for Alzheimer's disease, including the elucidation of changes in the brain revealed by structural and functional neuroimaging, as well as the characteristic patterns of cognitive decline that are documented by sensitive neuropsychological tests, various genetic markers, and biological assays. Early Diagnosis of Alzheimer's Disease illuminates the complex issues surrounding the search for early markers of this increasingly widespread disease. It will establish a new standard reference guide for all those working with Alzheimer's patients.

Author : Jonas H. Ellenberg,William C. Koller,James William Langston
Publisher : CRC Press
Page : 600 pages
File Size : 46,6 Mb
Release : 1995-03-01
Category : Medical
ISBN : 0824788230

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Etiology of Parkinson's Disease by Jonas H. Ellenberg,William C. Koller,James William Langston Pdf

This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Author : Sylvain Lehmann,Charlotte Elisabeth Teunissen
Publisher : Frontiers Media SA
Page : 220 pages
File Size : 53,8 Mb
Release : 2016-11-10
Category : Electronic book
ISBN : 9782889450411

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Biomarkers of Alzheimer's Disease: The Present and the Future by Sylvain Lehmann,Charlotte Elisabeth Teunissen Pdf

Alzheimer disease (AD) is a neurodegenerative disorder characterized by significant cognitive deficits, behavioral changes, sleep disorders and loss of functional autonomy. AD represents the main cause of dementia and has become a major public health issue. In addition, the number of patients suffering from AD is growing rapidly as the population ages worldwide. Memory impairment is usually the earliest clinical and core symptom of this disease. The diagnosis at a late clinical stage is relatively easy. However, a delay in the diagnosis is damageable for the handling of patients in terms of optimal medical and social care. The actual interest of the scientific head-ways is to optimize the diagnosis in prodromal stage of the disease and to propose personalized therapeutic solutions to individual patients. New revised AD diagnostic criteria include early alteration of cerebrospinal fluid (CSF) biomarkers: decrease of amyloïd peptides (Aβ42), and increase in tau and phosphorylated-tau (p-tau) protein concentration. This recognition of CSF biological biomarkers for the diagnosis of AD is a major step towards the “molecular” diagnosis and follow-up of the disease. Many issues are however still subject of debate. This e-book provides a comprehensive overview of the state of the art of fluid biomarkers for AD, e.g. which novel biomarkers should be implemented in clinical practice for diagnosis or for monitoring treatment or side effects, which ones are new for AD or related dementias or what is the potential of peripheral blood markers. Moreover, the e-Book provides practical guidelines how to optimally and efficiently develop and validate novel biomarker assays, and to document and control pre-analytical variation.

Author : Erika Rovini,Valeria Manera,Peter Edward Wais
Publisher : Frontiers Media SA
Page : 120 pages
File Size : 44,9 Mb
Release : 2023-03-30
Category : Science
ISBN : 9782832519219

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Early Detection of Neurodegenerative Disorders Using Behavioral Markers and New Technologies: New Methods and Perspectives by Erika Rovini,Valeria Manera,Peter Edward Wais Pdf

Author : Sarika Singh,Neeraj Joshi
Publisher : Springer
Page : 301 pages
File Size : 54,5 Mb
Release : 2018-09-24
Category : Medical
ISBN : 9789811309441

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Pathology, Prevention and Therapeutics of Neurodegenerative Disease by Sarika Singh,Neeraj Joshi Pdf

This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases

Author : Abraham Fisher,Maurizio Memo,Fabrizio Stocchi,Israel Hanin
Publisher : Springer Science & Business Media
Page : 490 pages
File Size : 55,7 Mb
Release : 2007-12-26
Category : Medical
ISBN : 9780387720760

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Advances in Alzheimer's and Parkinson's Disease by Abraham Fisher,Maurizio Memo,Fabrizio Stocchi,Israel Hanin Pdf

This volume contains the proceedings of the 2005 ADPD conference and is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, which covering topics from immunology, neuroscience, and pharmacology to genetics and molecular biology. Possible future developments in the treatment of Alzheimer’s and Parkinson’s Diseases are also covered.

Author : Lars Lannfelt,Martin Ingelsson
Publisher : Unknown
Page : 289 pages
File Size : 42,9 Mb
Release : 2016
Category : Biochemical markers
ISBN : 1493935607

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Immunotherapy and Biomarkers in Neurodegenerative Disorders by Lars Lannfelt,Martin Ingelsson Pdf

Author : Ivan Bodis-Wollner,Nicolás Cuenca,Raymond Chuen-Chung Chang
Publisher : Frontiers Media SA
Page : 106 pages
File Size : 53,7 Mb
Release : 2020-01-20
Category : Electronic
ISBN : 9782889634347

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Behold the Eye in Parkinson's Disease & Alzheimer’s Disease by Ivan Bodis-Wollner,Nicolás Cuenca,Raymond Chuen-Chung Chang Pdf

There are increasing lines of evidence showing that neurodegeneration in Alzheimer’s disease (AD) and Parkinson’s disease (PD) is not limited to the brain but also occurs in the retina. Consequently, AD/PD patients can gradually develop vision problems. This neurological and ophthalmological disorder creates a pressing need for developing therapy to treat vision impairment in AD/PD. On the other hand, pathophysiological changes in the retina may reflect what might happen in the same diseases in the brain. Thus retinal studies may allow us to develop quantifiable measures for the diagnosis and prognosis of disease progression. Furthermore, parallel or early pathophysiological changes of the retina in AD/PD allow us to study retina-brain interactions.

Author : Daniela Galimberti,Elio Scarpini
Publisher : Springer
Page : 407 pages
File Size : 41,5 Mb
Release : 2018-03-15
Category : Medical
ISBN : 9783319729381

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Neurodegenerative Diseases by Daniela Galimberti,Elio Scarpini Pdf

This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson’s disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.

Author : Israel Hanin,Mitsuo Yoshida,Abraham Fisher
Publisher : Springer Science & Business Media
Page : 690 pages
File Size : 41,7 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475791457

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Alzheimer’s and Parkinson’s Diseases by Israel Hanin,Mitsuo Yoshida,Abraham Fisher Pdf

This book represents the third in a series of International Conferences related to Alzheimer's (AD) and Parkinson's (PD) diseases. The first one took place in Eilat, Israel, in 1985; and the second one in Kyoto, Japan, in 1989. This book contains the full text of oral and poster presentations from the Third International Conference on Alzheimer's and Parkinson's Diseases: Recent Developments, held in Chicago, Illinois, U.S.A. on November 1-6, 1993. The Chicago Conference was attended by 270 participants. The Scientific Program was divided into nine oral sessions, a keynote presentation, and a poster session. The conference culminated in a Round Table Discussion involving all of the participants in the conference. The four and one-half day meeting served as an excellent medium for surveying the current status of clinical and preclinical developments in AD and PD. There were 59 oral presentations and 93 posters. This book incorporates a majority of both.

Author : Mohamed Mosaad Salama,Stefania Mondello,Firas H. Kobeissy,Wael M. Y. Mohamed
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 53,6 Mb
Release : 2020-05-12
Category : Electronic
ISBN : 9782889636938

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Biomarkers in Neurology by Mohamed Mosaad Salama,Stefania Mondello,Firas H. Kobeissy,Wael M. Y. Mohamed Pdf

Author : David Crosiers,Patrick Santens,K. Ray Chaudhuri
Publisher : Frontiers Media SA
Page : 90 pages
File Size : 50,7 Mb
Release : 2021-02-17
Category : Medical
ISBN : 9782889664894

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Prodromal Parkinson’s Disease by David Crosiers,Patrick Santens,K. Ray Chaudhuri Pdf

Author : Silvia Mandel
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 46,9 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9789400758667

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Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future by Silvia Mandel Pdf

This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection Multiple sclerosis related biomarkers: perspectives for clinical application Preventive clinical trials in brain aging: new trends & the need of guidelines MCI_ clinical guidelines in early diagnosis of dementia Alzheimer's disease: diagnostics, prognostics and the road to prevention Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms