Economic Evaluation In Clinical Trials

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Economic Evaluation in Clinical Trials

Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad,Daniel Polsky
Economic Evaluation in Clinical Trials Book PDF

Author : Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad,Daniel Polsky
Publisher : OUP Oxford
Page : 288 pages
File Size : 45,9 Mb
Release : 2014-10-02
Category : Medical
ISBN : 9780191508066

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Economic Evaluation in Clinical Trials by Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad,Daniel Polsky Pdf

It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also vital for addressing the requirements of regulatory bodies. Economic Evaluation in Clinical Trials provides practical advice on how to conduct cost-effectiveness analyses in controlled trials of medical therapies. This new edition has been extensively rewritten and revised; topics discussed range from design issues such as the types of services that should be measured and price weights, to assessment of quality-adjusted life years. Illustrative materials, case histories and worked examples are included to encourage the reader to apply the methods discussed. These exercises are supported with datasets, programmes and solutions made available online.

Economic Evaluation in Clinical Trials

Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad
Economic Evaluation in Clinical Trials Book PDF

Author : Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad
Publisher : Handbooks in Health Economic E
Page : 265 pages
File Size : 51,7 Mb
Release : 2014-10-02
Category : Business & Economics
ISBN : 9780199685028

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Economic Evaluation in Clinical Trials by Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad Pdf

It is increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. This book provides a practical guide to the techniques and issues involved in conducting economic evaluation in ongoing clinical trials, supported with examples.

Economic Evaluation in Clinical Trials

Henry Glick
Economic Evaluation in Clinical Trials Book PDF

Author : Henry Glick
Publisher : Oxford University Press
Page : 258 pages
File Size : 53,9 Mb
Release : 2007-02-15
Category : Business & Economics
ISBN : 9780198529972

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Economic Evaluation in Clinical Trials by Henry Glick Pdf

The book provides a practical guide to conducting economic evaluation in ongoing clinical trials. It covers issues and techniques related to the collection of both cost and outcome data, as well as a framework for reporting and interpreting economic reports from clinical trials.

Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement

Iftekhar Khan
Design Analysis of Clinical Trials for Economic Evaluation Reimbursement Book PDF

Author : Iftekhar Khan
Publisher : CRC Press
Page : 339 pages
File Size : 55,9 Mb
Release : 2015-11-11
Category : Mathematics
ISBN : 9781466505483

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Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement by Iftekhar Khan Pdf

Economic evaluation has become an essential component of clinical trial design to show that new treatments and technologies offer value to payers in various healthcare systems. Although many books exist that address the theoretical or practical aspects of cost-effectiveness analysis, this book differentiates itself from the competition by detailing

Economic Evaluation of Cancer Drugs

Iftekhar Khan,Ralph Crott,Zahid Bashir
Economic Evaluation of Cancer Drugs Book PDF

Author : Iftekhar Khan,Ralph Crott,Zahid Bashir
Publisher : CRC Press
Page : 416 pages
File Size : 53,6 Mb
Release : 2019-06-14
Category : Mathematics
ISBN : 9781498761314

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Economic Evaluation of Cancer Drugs by Iftekhar Khan,Ralph Crott,Zahid Bashir Pdf

Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity’s Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.

Economic Evaluation in Healthcare

Gordon Mallarkey
Economic Evaluation in Healthcare Book PDF

Author : Gordon Mallarkey
Publisher : Lippincott Williams & Wilkins
Page : 208 pages
File Size : 54,8 Mb
Release : 1999
Category : Medical
ISBN : UVA:X004439375

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Economic Evaluation in Healthcare by Gordon Mallarkey Pdf

The purpose of economic evaluations in healthcare is to affect decision making. So how do you determine the best use of scarce resources, in terms of benefits gained from expenditures? The purpose of this book is to review the methods of economic evaluation and how they may be used optimally, and with practical results. It includes review articles on familiar analytical tools, opinion papers on areas of contention, and guidelines on how to apply and analyse economics tools, methods and models.

Methods for the Economic Evaluation of Health Care Programmes

M. F. Drummond
Methods for the Economic Evaluation of Health Care Programmes Book PDF

Author : M. F. Drummond
Publisher : Unknown
Page : 404 pages
File Size : 51,8 Mb
Release : 2005
Category : Business & Economics
ISBN : 0198529457

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Methods for the Economic Evaluation of Health Care Programmes by M. F. Drummond Pdf

The highly successful textbook Methods for the Economic Evaluation of Health Care is now available in its third edition. Over the years it has become the standard textbook in the field world-wide. It mirrors the huge expansion of the field of economic evaluation in health care. This new edition builds on the strengths of previous editions being clearly written in a style accessible to a wide readership. Key methodological principles are outlined using a critical appraisal checklist that can be applied to any published study. The methodological features of the basic forms of analysis are then explained in more detail with special emphasis of the latest views on productivity costs, the characterization of uncertainty and the concept of net benefit. The book has been greatly revised and expanded especially concerning analyzing patient-level data and decision-analytic modeling. There is discussion of new methodological approaches, including cost effectiveness acceptability curves, net benefit regression, probalistic sensitivity analysis and value of information analysis. There is an expanded chapter on the use of economic evaluation, including discussion of the use of cost-effectiveness thresholds, equity considerations and the transferability of economic data. This new edition is required for anyone commissioning, undertaking or using economic evaluations in health care, and will be popular with health service professionals, health economists, pharmacists and health care decision makers. It is especially relevant for those taking pharmacoeconomics courses.

Handbook of EHealth Evaluation

Francis Yin Yee Lau,Craig Kuziemsky
Handbook of EHealth Evaluation Book PDF

Author : Francis Yin Yee Lau,Craig Kuziemsky
Publisher : Unknown
Page : 487 pages
File Size : 51,9 Mb
Release : 2016-11
Category : Medical care
ISBN : 1550586017

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Handbook of EHealth Evaluation by Francis Yin Yee Lau,Craig Kuziemsky Pdf

To order please visit https://onlineacademiccommunity.uvic.ca/press/books/ordering/

Economic Evaluation of Cancer Drugs

Iftekhar Khan (Statistician),Ralph Crott,Zahid Bashir
Economic Evaluation of Cancer Drugs Book PDF

Author : Iftekhar Khan (Statistician),Ralph Crott,Zahid Bashir
Publisher : Chapman & Hall/CRC
Page : 416 pages
File Size : 40,9 Mb
Release : 2019-06-14
Category : HEALTH & FITNESS
ISBN : 0429546548

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Economic Evaluation of Cancer Drugs by Iftekhar Khan (Statistician),Ralph Crott,Zahid Bashir Pdf

Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity's Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics? at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.

Measuring and Valuing Health Benefits for Economic Evaluation

John Brazier,Julie Ratcliffe,Joshua Saloman,Aki Tsuchiya
Measuring and Valuing Health Benefits for Economic Evaluation Book PDF

Author : John Brazier,Julie Ratcliffe,Joshua Saloman,Aki Tsuchiya
Publisher : Oxford University Press
Page : 373 pages
File Size : 50,8 Mb
Release : 2017
Category : Medical
ISBN : 9780198725923

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Measuring and Valuing Health Benefits for Economic Evaluation by John Brazier,Julie Ratcliffe,Joshua Saloman,Aki Tsuchiya Pdf

With limited resources and funding, it is impossible to invest in all potentially beneficial health care interventions. Choices have to be made, and this guide allows the reader to measure and value the benefits of interventions, a key component of economic evaluation, which permits comparisons between interventions.

Economic Evaluation in Health Care

Michael Drummond,M. F. Drummond,Alistair McGuire
Economic Evaluation in Health Care Book PDF

Author : Michael Drummond,M. F. Drummond,Alistair McGuire
Publisher : Unknown
Page : 298 pages
File Size : 49,8 Mb
Release : 2001
Category : Business & Economics
ISBN : 9780192631770

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Economic Evaluation in Health Care by Michael Drummond,M. F. Drummond,Alistair McGuire Pdf

To accompany the hugely sccessful 'Methods for Economic Evaluation of Health Care Programmes 2e', this book is a thorough and rigourous discussion of the methodological principles and recent advances in the rapidly advancing field of theory and practice of economic evaluation in health care. Written by an internationally acclaimed group of authors, the book provides an in-depth discussion of the latest theoretical advances and gives comprehensive reviews of the available literature. The book covers the main areas of economic evaluation, including the methods for measuring costs and outcomes, the collection of data alongside clinical studies, ways of handling uncertainty, discounting and issues relating to the transferability of economic data. It is an ideal book for those studying economic evaluation on postgraduate or professional courses in health economics or public health.

Applied Methods of Cost-effectiveness Analysis in Healthcare

Alastair M. Gray,Philip M. Clarke,Jane L. Wolstenholme,Sarah Wordsworth
Applied Methods of Cost effectiveness Analysis in Healthcare Book PDF

Author : Alastair M. Gray,Philip M. Clarke,Jane L. Wolstenholme,Sarah Wordsworth
Publisher : Oxford University Press
Page : 326 pages
File Size : 53,5 Mb
Release : 2011
Category : Business & Economics
ISBN : 9780199227280

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Applied Methods of Cost-effectiveness Analysis in Healthcare by Alastair M. Gray,Philip M. Clarke,Jane L. Wolstenholme,Sarah Wordsworth Pdf

This book provides the reader with a comprehensive set of instructions and examples of how to perform an economic evaluation of a health intervention, focusing solely on cost-effectiveness analysis in healthcare.

Economic Evaluation in Child Health

Wendy Ungar
Economic Evaluation in Child Health Book PDF

Author : Wendy Ungar
Publisher : OUP Oxford
Page : 0 pages
File Size : 41,5 Mb
Release : 2009-10-08
Category : Medical
ISBN : 0199547491

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Economic Evaluation in Child Health by Wendy Ungar Pdf

Guidelines for conducting health economic evaluations have become increasingly standardized, however they don't address the unique concerns of the paediatric population. This is the first textbook to address economic evaluation in child health.

Economic and Medical Evaluation of Health Care Technologies

A. J. Culyer,B. Horisberger
Economic and Medical Evaluation of Health Care Technologies Book PDF

Author : A. J. Culyer,B. Horisberger
Publisher : Springer Science & Business Media
Page : 422 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642694394

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Economic and Medical Evaluation of Health Care Technologies by A. J. Culyer,B. Horisberger Pdf

All too frequently, the largest effective barrier to interdisciplinary communication is jargon. The symposium whose proceedings appear in the following pages sought, of course, to eliminate unnecessary and obscurantist jargon; but it sought also to do something far more ambitious - to confront the intellectual issues that are attached to the use of the word "evaluation" in medicine and health services. To this end a carefully selected group of experts in medicine, epidemiology, and health econom ics was invited to present papers. They were selected for their reputations either as conceptualizers or as empirical evaluators, or - the rarest breed of expert - as both. The context was to be empirical. Three procedures were selected that had been subject to evaluation but that posed rather different types of problem. The first was the treatment of renal failure by dialysis of various kinds. This has a relatively long history of evaluation, with a large literature, and particularly raises broad policy is sues within the health services of Western societies as to - the size of programmes to be provided; the type, location, and mix of treatments; the selection of patients to receive treatment; and the measurement of the success of various strategies. The second was the treatment of duodenal ulcer by a new species of drug - the hista mine Hrreceptor antagonists (specifically, cimetidine).

Decision Modelling for Health Economic Evaluation

Andrew Briggs,Mark Sculpher,Karl Claxton
Decision Modelling for Health Economic Evaluation Book PDF

Author : Andrew Briggs,Mark Sculpher,Karl Claxton
Publisher : OUP Oxford
Page : 256 pages
File Size : 55,5 Mb
Release : 2006-08-17
Category : Medical
ISBN : 9780191004957

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Decision Modelling for Health Economic Evaluation by Andrew Briggs,Mark Sculpher,Karl Claxton Pdf

In financially constrained health systems across the world, increasing emphasis is being placed on the ability to demonstrate that health care interventions are not only effective, but also cost-effective. This book deals with decision modelling techniques that can be used to estimate the value for money of various interventions including medical devices, surgical procedures, diagnostic technologies, and pharmaceuticals. Particular emphasis is placed on the importance of the appropriate representation of uncertainty in the evaluative process and the implication this uncertainty has for decision making and the need for future research. This highly practical guide takes the reader through the key principles and approaches of modelling techniques. It begins with the basics of constructing different forms of the model, the population of the model with input parameter estimates, analysis of the results, and progression to the holistic view of models as a valuable tool for informing future research exercises. Case studies and exercises are supported with online templates and solutions. This book will help analysts understand the contribution of decision-analytic modelling to the evaluation of health care programmes. ABOUT THE SERIES: Economic evaluation of health interventions is a growing specialist field, and this series of practical handbooks will tackle, in-depth, topics superficially addressed in more general health economics books. Each volume will include illustrative material, case histories and worked examples to encourage the reader to apply the methods discussed, with supporting material provided online. This series is aimed at health economists in academia, the pharmaceutical industry and the health sector, those on advanced health economics courses, and health researchers in associated fields.