Electrochemistry Of Nucleic Acids And Proteins

Author : E. Palecek,F. Scheller,J. Wang
Publisher : Elsevier
Page : 809 pages
File Size : 54,5 Mb
Release : 2005-12-19
Category : Science
ISBN : 9780080457451

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Electrochemistry of Nucleic Acids and Proteins by E. Palecek,F. Scheller,J. Wang Pdf

DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century. * Covers highly sophisticated methods of electrochemical analysis of nucleic acids and proteins * Summarises the present state of electrochemical analysis of nucleic acids and proteins * Includes future trends in the electrochemical analysis in genomics and proteomics

Author : Miroslav Fojta,Emil Palecek
Publisher : Springer
Page : 350 pages
File Size : 51,6 Mb
Release : 2012-07-28
Category : Science
ISBN : 3540699317

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Nucleic-Acid Electrochemistry by Miroslav Fojta,Emil Palecek Pdf

This first monograph dedicated to the electrochemistry of nucleic acids offers complete coverage of the field. Modern electrochemical methods, in connection with different electrode types, are able to detect DNA, RNA or their synthetics analogues at attomole or even lower levels. In recent years, significant progress was achieved in the development of electrochemical techniques and sensors for DNA hybridization, DNA damage, interactions of nucleic acids with drugs, genotoxic species and other small molecules, as well as DNA-protein interactions. These sensors are expected to become important tools in biomedicine and other areas of practical life of the 21st century. Here, the authors describe the necessary experimental setup for electrochemical studies of nucleic acids, the properties and behavior of nucleic acids at electrode surfaces as well as the analytical applications of nucleic acid electrochemistry. All this information is presented with numerous worked examples and color figures.

Author : Giorgio Lenaz,Giulio Milazzo
Publisher : Birkhäuser
Page : 397 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783034891790

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Bioelectrochemistry of Biomacromolecules by Giorgio Lenaz,Giulio Milazzo Pdf

Bioelectrochemistry: Principles and Practice provides a comprehensive compilation of all the physicochemical aspects of the different biochemical and physiological processes. Macromolecules, essentially nucleic acids, proteins and complex carbohydrates, are the building blocks of cell structure and function. This fifth volume in the "Bioelectrochemistry" series deals essentially with water-soluble biomacromolecules, since the properties of membrane-bound proteins are considered in other volumes of this series. The first chapter provides an extensive review of the structure, chemical reactivity and electromagnetic properties of nucleic acids. The following five chapters concentrate on proteins, their structure, folding and function, the electrochemistry of redox proteins and voltammetric methods. Special attention is devoted to the field of thiol/disulfide exchange as well as to one particular class of proteins, the iron-sulfur proteins. The last chapter considers the chemistry and properties of glycosaminoglycans, the complex charged polysaccharides of the cell surface and extracellular matrix. This series is intended as a set of source books for graduate and postgraduate students as well as research workers at all levels in bioelectrochemistry.

Author : Thomas E. Creighton
Publisher : Damaris Publishing
Page : 774 pages
File Size : 40,6 Mb
Release : 2010
Category : Catalysis
ISBN : 0956478115

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The Biophysical Chemistry of Nucleic Acids & Proteins by Thomas E. Creighton Pdf

DNA, RNA and proteins are undoubtedly the most important biological molecules. Being large macromolecules, their physical, chemical and biological properties can differ from those of the monomers from which they are made. This book describes their structures, origins and other key issues.

Author : F. Korte
Publisher : Elsevier
Page : 240 pages
File Size : 47,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323159432

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Nucleic Acids, Proteins and Carbohydrates by F. Korte Pdf

Methodicum Chimicum, Volume 11: Natural Compounds, Part 1: Nucleic acids, Proteins and Carbohydrates is devoted to the methods of structural determinations and syntheses of natural products. This text contains four chapters that include a short discussion of the principles of well-proved analytic procedures. It primarily describes the chemistry and biochemistry of nucleic acids, proteins, carbohydrates, and lipids. Other general topics covered include the components, chemical synthesis, sequences, primary structure, and classification of these macromolecules. This book is of value to chemists and scientists who works in associated areas, including medicine.

Author : W. Guschlbauer
Publisher : Springer Science & Business Media
Page : 155 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461393979

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Nucleic Acid Structure by W. Guschlbauer Pdf

Teaching a course on nucleic acid structure is a hazardous undertaking, especially if one has no continuous teaching obligations. I still have done it on several occasions in various French universities, when colleagues, suffering from admin istrative overwork and excessive teaching obligations, had asked me to do so. This was generally done with a pile of notes and a dozen slides, and I always regretted that no small, concise, specialized book on nucleic acid structure for students at the senior or beginning graduate level ex isted. Every year, the lecture notes became more and more voluminous, with some key reprints intermingled. Everything changed when, in the spring of 1973, I re ceived an invitation to teach such a course, under the UNESCO-OAS-Molecular Biology Program at the Universi dad de Chile in Santiago during October 1973. I had ac cepted rather enthusiastically, but soon discovered that it would be necessary to produce a photocopied syllabus for the students. This was the fi rst premanuscript of this book. For nonscientific reasons, the course was first canceled and then postponed until December 1973. Nearly a year later, the course, in slightly amended form, was presented at the Lemonossow-State University in Moscow.

Author : Peter Horsman,Brian E. Conway,E. Yeager
Publisher : Springer Science & Business Media
Page : 552 pages
File Size : 47,7 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781461323594

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Comprehensive Treatise of Electrochemistry by Peter Horsman,Brian E. Conway,E. Yeager Pdf

1.1. Definition of Terms-Thrombosis, Thromboembolic Disease, Atherosclerosis, and Blood Clotting The terms heart attack or myocardial infarction are more commonly used than thrombosis. The infarct-muscle destruction is simply the end result and thrombosis is the real cause of the heart attack. Thrombosis may be defined as the process of formation of a coalescent or agglutinated solid mass of blood components in the blood stream. Thrombi formed in either arteries or veins often cause occlusion in the vascular system and prevent blood flow. Obstruc to the blood vessel usually occurs at the site where the thrombi deposit. tion Furthermore, thrombi may break loose, travel through the circulating blood stream, and cause obstruction at some distal point of narrowing elsewhere. The mass or thrombus that moves is referred to as an "embolus." The two phenomena are lumped together under the term thromboembolic disease. Thrombosis that reduces blood supply to the heart is the primary factor in heart attacks.

Author : Robert Carter Allen,Bruce Budowle
Publisher : Unknown
Page : 376 pages
File Size : 42,8 Mb
Release : 1994
Category : Business & Economics
ISBN : UOM:39015032610688

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Gel Electrophoresis of Proteins and Nucleic Acids by Robert Carter Allen,Bruce Budowle Pdf

Author : Mehmet Sengun Ozsoz
Publisher : CRC Press
Page : 568 pages
File Size : 51,7 Mb
Release : 2012-04-23
Category : Science
ISBN : 9789814241779

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Electrochemical DNA Biosensors by Mehmet Sengun Ozsoz Pdf

This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.

Author : Phoebe A. Rice,Carl C. Correll
Publisher : Royal Society of Chemistry
Page : 417 pages
File Size : 48,6 Mb
Release : 2008-05-22
Category : Science
ISBN : 9780854042722

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Protein-Nucleic Acid Interactions by Phoebe A. Rice,Carl C. Correll Pdf

This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.

Author : Christoph Scholtissek
Publisher : Unknown
Page : 246 pages
File Size : 51,8 Mb
Release : 1966
Category : Science
ISBN : UOM:39015078677237

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Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins by Christoph Scholtissek Pdf

Author : Juan M. Feliu Martinez,Victor Climent Paya
Publisher : EOLSS Publications
Page : 450 pages
File Size : 54,5 Mb
Release : 2009-10-20
Category : Electronic
ISBN : 9781848262195

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Electrochemistry by Juan M. Feliu Martinez,Victor Climent Paya Pdf

Electrochemistry theme is a component of Encyclopedia of Physical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Electrochemistry is the science that studies the properties and chemical transformations of/within ionic conductors (most commonly a solution of a salt) and at the interface between an ionic conductor and an electronic conductor (most commonly a metal) or semiconductor. Electrochemistry is present in many aspects of our everyday life. Probably, batteries are the most common example. However, electrochemistry is also present in many other aspects of vital importance in the chemical industry, like chlorine, caustic soda and aluminum (and many others not described here) are produced through electrochemical processes. This volume is aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs

Author : Christoph Scholtissek,B M Richards,R Vendrely
Publisher : Unknown
Page : 244 pages
File Size : 54,7 Mb
Release : 1966-01-01
Category : Electronic
ISBN : 3709155703

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Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins by Christoph Scholtissek,B M Richards,R Vendrely Pdf

Author : Christoph Scholtissek
Publisher : Unknown
Page : 128 pages
File Size : 40,5 Mb
Release : 1962
Category : Electronic
ISBN : OCLC:879101950

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Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins by Christoph Scholtissek Pdf

Author : A. D. McLaren,D. Shugar
Publisher : Elsevier
Page : 470 pages
File Size : 41,6 Mb
Release : 2014-05-16
Category : Science
ISBN : 9781483150130

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Photochemistry of Proteins and Nucleic Acids by A. D. McLaren,D. Shugar Pdf

Photochemistry of Proteins and Nucleic Acids deals with photobiology. The book briefly introduces the principles of photochemistry, with a short discussion on absorption spectra and related absorbing structures, as well as on the general nature of photochemical reactions in solutions. The following information covers how proteins, nucleic acids, viruses, and their basic structures are chemically and physically affected when exposed to visible radiation and ultraviolet light. The book explains that the site of action of the ultraviolet light when applied to proteins in a small active center shows that other parts of the protein are also affected, considered as an energy transfer. Then the general conclusions pertaining to the physicochemical and chemical changes in nucleic acids through directed radiation doses that are big enough to induce modifications are enumerated. The text further explains that the physicochemical modifications, which occur when proteins are irradiated, can accompany loss in enzyme activity. The kinetics of inactivation of dry enzymes is compared to the photochemistry of enzymes in a solution. The inactivation of viruses is important as the process of replication can cause some formed viruses to spread in its environment, worsening the state of infection. Hence, the problem which components in a biological system absorb effective radiation is analyzed. The book is suitable for microbiologists, microchemists, and laboratory researchers and scientists dealing with infectious diseases.