Endocannabinoid Regulation Of Monoamines In Psychiatric And Neurological Disorders

Author : Elisabeth J. Van Bockstaele
Publisher : Springer Science & Business Media
Page : 341 pages
File Size : 44,5 Mb
Release : 2013-07-07
Category : Medical
ISBN : 9781461479406

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Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders by Elisabeth J. Van Bockstaele Pdf

The past decade has seen tremendous growth in the study of cannabinoid receptor signaling in brain. The impact and consequences of cannabinoid modulation of monoaminergic (dopamine, norepinephrine, and serotonin) circuits is becoming more clear. Scientists have shown significant interaction between these two systems in a variety of psychiatric and neurological disorders such as affective disorders, multiple sclerosis, and pain or pain disorders. The overarching goal of Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders is to provide current information on advances in the field of endocannabinoid signaling and potential therapeutic applications with a particular emphasis on monoaminergic circuits. ​

Author : Attila Köfalvi
Publisher : Springer Science & Business Media
Page : 583 pages
File Size : 55,9 Mb
Release : 2007-12-22
Category : Medical
ISBN : 9780387743493

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Cannabinoids and the Brain by Attila Köfalvi Pdf

Endocannabinoids have tremendous therapeutic potential. This book introduces readers to our current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential. Authors, experienced clinical investigators, present and analyze results of recent clinical trials as well as the development of new therapeutic strategies and medicines.

Author : Yogesh Dwivedi
Publisher : CRC Press
Page : 485 pages
File Size : 44,7 Mb
Release : 2012-06-25
Category : Medical
ISBN : 9781439838815

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The Neurobiological Basis of Suicide by Yogesh Dwivedi Pdf

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Author : Peter Riederer,Gerd Laux,Toshiharu Nagatsu,Weidong Le,Christian Riederer
Publisher : Springer Nature
Page : 4652 pages
File Size : 44,8 Mb
Release : 2022-11-04
Category : Medical
ISBN : 9783030620592

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NeuroPsychopharmacotherapy by Peter Riederer,Gerd Laux,Toshiharu Nagatsu,Weidong Le,Christian Riederer Pdf

This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.

Author : Judith Pratt,Jeremy Hall
Publisher : Springer
Page : 437 pages
File Size : 42,5 Mb
Release : 2019-01-05
Category : Medical
ISBN : 9783319996424

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Biomarkers in Psychiatry by Judith Pratt,Jeremy Hall Pdf

This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

Author : Qi Wang,Di Wen,Yixiao Luo,Fanglin Guan,Jianfeng Liu,Zeng Xiao Feng
Publisher : Frontiers Media SA
Page : 271 pages
File Size : 53,9 Mb
Release : 2022-02-02
Category : Science
ISBN : 9782889742592

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Stimulant Use and Addictive Disorder by Qi Wang,Di Wen,Yixiao Luo,Fanglin Guan,Jianfeng Liu,Zeng Xiao Feng Pdf

Author : Liana Fattore
Publisher : Academic Press
Page : 499 pages
File Size : 44,5 Mb
Release : 2015-01-23
Category : Medical
ISBN : 9780124171244

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Cannabinoids in Neurologic and Mental Disease by Liana Fattore Pdf

The application of cannabis sativa for the treatment of neurologic and mental disease is expanding. Cannabinoids in Neurologic and Mental Disease collects and presents for the first time recent research involving the use of pharmacological cannabinoids for the treatment of neurodegenerative and neuroinflammatory disease. The neurologic application of cannabinoid therapy builds upon psychiatric and psychological use for the treatment of a variety of core mental disorders. This comprehensive reference on the known uses of cannabinoids will be useful for clinical neurologists, neuroscience and clinical neuroscience researchers, clinical psychologists and psychiatrists and the general medical community. A comprehensive reference on the clinical uses of cannabinoids for treating major neurologic and mental diseases Detailed coverage of cannabinoid use for neuroinflammatory and neurodegenerative disease including Multiple Sclerosis, Epilepsy, Huntington's disease, Parkinson's disease, and Alzheimer's disease Detailed coverage of cannabinoid use for major psychiatric and psychological diseases and disorders including schizophrenia, bipolar disorders, Tourette's syndrome, and post-traumatic stress disorder (PTSD)

Author : Patrizia Campolongo,Liana Fattore
Publisher : Springer
Page : 471 pages
File Size : 52,7 Mb
Release : 2015-05-18
Category : Medical
ISBN : 9781493922949

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Cannabinoid Modulation of Emotion, Memory, and Motivation by Patrizia Campolongo,Liana Fattore Pdf

The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation. In the brain, endocannabinoids regulate ion channel activity and neurotransmitter release and thereby contribute to various aspects of brain function, including memory, reward and emotions. Their ability to modulate synaptic efficacy has a wide range of functional consequences and provides unique therapeutic possibilities. Unprecedented advances have been made in the understanding of the role of endocannabinoids in the regulation of the emotional brain over the past few years. However, a comprehensive book encompassing all these aspects is still lacking. The book will provide an overview of the role played by the endocannabinoid system in the regulation of emotional processes with particular emphasis on the modulation of memory and reward for emotionally arousing events and for the regulation of motivational aspects in cannabis use.

Author : Rudy Schreiber
Publisher : Springer Nature
Page : 285 pages
File Size : 46,6 Mb
Release : 2021-06-17
Category : Medical
ISBN : 9783030623517

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Modern CNS Drug Discovery by Rudy Schreiber Pdf

This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.

Author : Marco Colizzi,Sagnik Bhattacharyya,Danilo De Gregorio,Mirella Ruggeri
Publisher : Frontiers Media SA
Page : 139 pages
File Size : 46,6 Mb
Release : 2022-01-24
Category : Medical
ISBN : 9782889741489

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The Endocannabinoid System: Filling the Translational Gap between Neuroscience and Psychiatry by Marco Colizzi,Sagnik Bhattacharyya,Danilo De Gregorio,Mirella Ruggeri Pdf

Author : Heinz Steiner,Kuei Y. Tseng
Publisher : Academic Press
Page : 704 pages
File Size : 40,8 Mb
Release : 2010-03-17
Category : Medical
ISBN : 9780080912158

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Handbook of Basal Ganglia Structure and Function by Heinz Steiner,Kuei Y. Tseng Pdf

The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

Author : David Castle,Robin Murray
Publisher : Cambridge University Press
Page : 238 pages
File Size : 48,8 Mb
Release : 2004-05-27
Category : Medical
ISBN : 1139451650

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Marijuana and Madness by David Castle,Robin Murray Pdf

This book provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana), with particular emphasis on psychotic disorders. It outlines developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illness such as schizophrenia. A number of controversial issues are critically explored, including whether a discrete 'cannabis psychosis' exists, and whether cannabis can actually cause schizophrenia. Effects of cannabis on mood, notably depression, are reviewed, as are its effects on cognition. This book will be of interest to all members of the mental health team, as well as to neuroscientists and those involved in drug and alcohol research.

Author : Dave Kendall,Stephen Alexander
Publisher : Springer Science & Business Media
Page : 418 pages
File Size : 48,8 Mb
Release : 2009-08-14
Category : Medical
ISBN : 9783540889557

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Behavioral Neurobiology of the Endocannabinoid System by Dave Kendall,Stephen Alexander Pdf

The endocannabinoid signaling system is a key modulator of central nervous function. This volume, essential reading for interested neuroscientists, provides in-depth coverage of the roles of the endocannabinoid signaling system in the neurobiology of behavior.

Author : M.A. Steiner,M. Yanagisawa,M. Clozel
Publisher : Karger Medical and Scientific Publishers
Page : 165 pages
File Size : 40,9 Mb
Release : 2021-05-28
Category : Health & Fitness
ISBN : 9783318068443

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The Orexin System. Basic Science and Role in Sleep Pathology by M.A. Steiner,M. Yanagisawa,M. Clozel Pdf

The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

Author : Mario Juruena
Publisher : BoD – Books on Demand
Page : 380 pages
File Size : 43,6 Mb
Release : 2012-02-29
Category : Science
ISBN : 9789535101772

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Clinical, Research and Treatment Approaches to Affective Disorders by Mario Juruena Pdf

The causes, development and outcomes of disorders are determined by the relationship of psychological, social and cultural factors with biochemistry and physiology. Biochemistry and physiology are not disconnected and different from the rest of our experiences and life events. This system is based on current studies that report that the brain and its cognitive processes show a fantastic synchronization. Written by the foremost experts on Affective Disorders worldwide, this book is characterized by its innovative, refreshing, and highly sensitive perspective on current knowledge of diagnostic, neurobiology, early life stress and treatment of Mood Disorders. The authors share a deep understanding of unique challenges and difficulties involved in Affective Disorders, and have achieved a balance among clinical, research and new treatment approaches to Affective Disorders. The chapters are written in a comprehensive, easily readable, and highly accessible style, stimulating readers, clinicians and researchers.