Endocrine Function And Aging

Author : H. James Armbrecht,Rodney M. Coe,Nirandon Wongsurawat
Publisher : Springer
Page : 256 pages
File Size : 53,7 Mb
Release : 2013-12-21
Category : Medical
ISBN : 9781461232407

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Endocrine Function and Aging by H. James Armbrecht,Rodney M. Coe,Nirandon Wongsurawat Pdf

One of the hallmarks of aging is the decreased capacity to adapt to changes in the environment. In a constant, controlled environment, it is often difficult to distin guish the functioning of the young organism from that of the old. However, when stresses are applied-temperature stresses, dietary stresses, infection, emotional stresses-the differences are more apparent. Frequently, the response ofthe old is delayed and may never reach the same mag'nitude as the young. These responses, in most cases, are mediated by the neuroendocrine system, which communicates via hormones, neurotransmitters, and related substances. Thus, it is important to understand the age-related changes that take place in the secretion and act ion of these substances and how these changes relate to the well-being of the whole organism. Indeed, the "neuroendocrine theory of aging" proposes that almost all of the characteristics of aging can be accounted for by dysfunction of the neuroendocrine system. A book on endocrine function and aging is particularly relevant at this time. With the advent of the techniques of molecular biology, there has bee~ an explo sion of knowledge concerning hormone secretion and action. Hormones, pro hormones, hormone receptors, and "second messenger" mediators rapidly are being cloned and sequenced. Such knowledge gives us important insights into the molecular workings of these substances as well as into the genetic hasis of endo crine dysfunction. These new tools are now being applied to the problem of age related changes in endocrine function.

Author : H. James Armbrecht
Publisher : Unknown
Page : 236 pages
File Size : 53,8 Mb
Release : 1990-01-01
Category : Endocrine glands
ISBN : 354097007X

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Endocrine Function and Aging by H. James Armbrecht Pdf

Author : Joseph Meites
Publisher : Springer Science & Business Media
Page : 394 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468445237

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Neuroendocrinology of Aging by Joseph Meites Pdf

JOSEPH MEITES The idea that the endocrine system is involved in aging processes is as old as the beginnings of endocrinology. The first endocrine experiment related to aging was reported by Brown-Sequard, who is usually re garded as the "father of endocrinology. " In 1889, at the age of 72 years, he reported that he had succeeded in rejuvenating himself by injections of testicular extracts from dogs and guinea pigs. Although the favorable effects observed may have been due mainly to the powers of auto suggestion, his reports created a considerable interest in endocrinology and its relation to aging, and eventually led to the use of estrogens for treating certain pre-and postmenopausal symptoms in women, and an drogens for treating some symptoms in aging men. Up to about the 1960's, the relatively few studies on endocrine-aging relationships dealt mainly with changes in weight and histological appearance of endocrine organs in aging animals and human subjects, and included a limited number of measurements of endocrine function by bioassays and chem ical (for steroids) procedures. Within these limitations, gerontological investigators were unable to establish any definite relationships between endocrine functions and aging processes, with the exception of the con nection between reproductive decline and gonadal and pituitary activity.

Author : Emiliano Corpas,Marc R. Blackman,S. Mitchell Harman,Antonio Ruiz-Torres
Publisher : Elsevier
Page : 788 pages
File Size : 42,9 Mb
Release : 2020-09-22
Category : Medical
ISBN : 9780128196670

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Endocrinology of Aging by Emiliano Corpas,Marc R. Blackman,S. Mitchell Harman,Antonio Ruiz-Torres Pdf

Endocrinology of Aging: Clinical Aspects in Diagrams and Images presents chapters in a way that allows the reader to incorporate concepts and complex facts in a visual way. As the global population becomes older, the need for a deeper understanding of geriatric pathology increases, and with it, there becomes a greater need to access educational resources on the endocrinology and metabolism of aging. According to the United Nations, the number of people aged 60 years or over in the world is projected to be 1.4 billion in 2030 and 2.1 billion in 2050, hence this is a timely resource. Divided according to specific endocrine and metabolic systems, providing evidence-based content Addresses physiological changes that alter the pathophysiology of the clinical picture Considers the patient transitioning from young adult to elderly, discussing endocrinological challenges to discern physiology from pathology Focuses on age as an essential factor for diagnostic and endocrine management

Author : Charles V. Mobbs,Patrick R. Hof
Publisher : Karger Medical and Scientific Publishers
Page : 254 pages
File Size : 52,9 Mb
Release : 1998-01-01
Category : Medical
ISBN : 9783805567268

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Functional Endocrinology of Aging by Charles V. Mobbs,Patrick R. Hof Pdf

One of the most demanding aspects regarding the endocrinology of aging is to determine the extent to which hormones change with age, independent of age-related pathologies, and the clinical significance of these changes. The emphasis of the present volume is on function, as it is of particular interest to many nonspecialists under what circumstances endocrine therapy may be useful in the elderly. For this purpose, leading investigators in their respective fields review the most important hormonal systems affected by aging. Furthermore, to facilitate the utility of the reviews particularly for nonspecialists, the book emphasizes the critical analysis of specific issues: The extent to which the hormones considered really do change with age, especially in humans; the physiological significance and the causes of these changes; and the prospects for treatment. Additionally, this volume also includes reviews on subjects such as cytokines, the sympathetic nervous system and leptin, which have not been traditionally considered in reviews of endocrine systems. However, while the concept of hormone replacement in the elderly is promising, as the chapters in the present volume indicate, much more research is necessary to determine under what circumstances such therapy is appropriate rather than counterproductive.

Author : P. Chanson,Jacques Epelbaum,S.W.J. Lamberts
Publisher : Springer Science & Business Media
Page : 231 pages
File Size : 45,6 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9783662070192

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Endocrine Aspects of Successful Aging: Genes, Hormones and Lifestyles by P. Chanson,Jacques Epelbaum,S.W.J. Lamberts Pdf

At the beginning of the 20th century, life expectancy at birth in North America and Western Europe was around 50 years of age. Nowadays, women have gained more than 30 years of age and men are trailing closer. However, according to several sociologists such as Louis Chauvel, the notion of a "greying society" is not entirely adequate since aging people are physically and socially younger and more active for a longer time. Of course, the other side of the medal is to tackle the challenge of preventing age-associated chronic diseases. In this book the extensive field of research on neuroendocrine aging has been reviewed. Aging is one of the most complex biological processes determined by the interactions between genetic and environmental factors.

Author : John E. Morley,Lucretia van den Berg
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 47,5 Mb
Release : 1999-11-05
Category : Medical
ISBN : 9781592597154

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Endocrinology of Aging by John E. Morley,Lucretia van den Berg Pdf

Distinguished physicians critically review the clinical consequences of the endocrinological changes that occur with aging-in both men and women-and examine the use of hormonal therapy to reduce them. Topics range from bone disease and water balance in all older people, to androgen deficiency in aging males, gynecomastia, and menopause. The authors also discuss Type II diabetes in persons over 65, emphasizing the cognitive benefits of good glycemia control, and the interaction of nutrition and metabolism, focusing on hypocholesterolemia, obesity, the anorexia of aging, trace elements, and vitamins. The aging of the sympathetic nervous system and its impact on hypertension in the elderly is also covered. Timely and authoritative, Endocrinology of Aging offers endocrinologists, geriatricians, and primary care physicians critical insight into the endocrine problems of our rapidly growing elderly population.

Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 312 pages
File Size : 40,5 Mb
Release : 2002-02-15
Category : Science
ISBN : 0471486361

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Endocrine Facets of Ageing by Derek J. Chadwick,Jamie A. Goode Pdf

Social and medical developments have recently led to a dramatic increase in life expectancy. This has inspired the study of organismic changes associated with healthy ageing, in particular the erosion of homeostatic capabilities in multiple endocrine systems. This book reviews advances in the understanding of endocrine facets of ageing. It considers the relative magnitudes and time courses of different endocrine adaptations in the ageing human and experimental animal, addressing the influence of external factors on the rates of progression of endocrine sequelae in ageing, the mechanisms that underlie the disarray of endocrine axes in ageing, and the implications of therapeutic reconstitution of hormones in ageing. This book: Considers the mechanisms of ageing and hormonal changes that occur with age. Discusses healthy ageing and the relationships between hormonal changes and pathophysiological conditions such as atherosclerosis and age-related bone loss. Draws together contributions from basic and clinical research, to identify and stimulate promising new research directions.

Author : Stanley G. Korenman
Publisher : North-Holland
Page : 296 pages
File Size : 52,6 Mb
Release : 1982
Category : Aging
ISBN : UCAL:B4979670

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Endocrine Aspects of Aging by Stanley G. Korenman Pdf

Author : William J. MacLennan,Norman R. Peden
Publisher : Springer Science & Business Media
Page : 205 pages
File Size : 43,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447116721

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Metabolic and Endocrine Problems in the Elderly by William J. MacLennan,Norman R. Peden Pdf

Illness in old age is characterised by vague and atypical presenting features which are often missed and wrongly attributed to the ageing process. This is particularly true of endocrine disorders where hypothyroidism may mas querade as dementia, where electrolyte imbalance may cause lassitude, and where diabetes mellitus may produce a wide range of complications com monly associated with ageing. It is our intention that our book provide straightforward practical guidance in this difficult area by delineating the effects of ageing on endocrine function and the clinical consequences of these; and by describing in detail the wide range of presenting clinical fea tures of endocrine disease in the elderly. Physicians are also often baffled and misled by the effects of ageing and disease on laboratory tests used in the investigation of endocrine disease. Our book describes these changes in detail, and gives guidance on which tests are most appropriate. Ageing and disease also produce subtle changes in the response of patients to drugs and replacement, and this is also dis cussed in detail. Subjects included separately and in depth include thyroid disease, the clinical features and treatment of diabetes, postmenopausal changes, bone disease, fluid and electrolyte imbalance, energy imbalance, and drugs caus ing endocrine and metabolic disorders. These have been chosen because we consider that they present problems which are particularly relevant to the elderly. Many other issues are covered in general textbooks of endocrin ology and have been omitted.

Author : Sandro La Vignera,Antonio Aversa,Fabio Monzani
Publisher : Frontiers Media SA
Page : 147 pages
File Size : 52,7 Mb
Release : 2019-12-04
Category : Electronic
ISBN : 9782889632343

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Endocrine Frailty in the Elderly by Sandro La Vignera,Antonio Aversa,Fabio Monzani Pdf

Author : Richard C. Adelman,George S. Roth
Publisher : CRC Press
Page : 431 pages
File Size : 46,5 Mb
Release : 2017-07-28
Category : Medical
ISBN : 9781351365987

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Endocrine and Neuroendocrine Mechanisms Of Aging by Richard C. Adelman,George S. Roth Pdf

It is the purpose of this volume to present a representative sampling of those neural and hormonal studies which have been the focus of the most intense interest in the recent gerontological research. To this end we have been fortunate to enlist the aid of some of the most competent and innovative investigators in the field. More than this, however, an attempt has been made to provide detailed methodological as well as theoretical evaluation for the areas considered. It is our hope that those researchers interested in this area of regulation during aging will be able to utilize the information contained herein as a basis both for critical analysis as well as for the designing and execution of further experiments in this more important area.

Author : Mary F. Morrison
Publisher : Cambridge University Press
Page : 379 pages
File Size : 45,5 Mb
Release : 2000-05-04
Category : Medical
ISBN : 9781139426459

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Hormones, Gender and the Aging Brain by Mary F. Morrison Pdf

The significance of hormone action in psychiatry has been long studied, now including the psychiatric effects of hormones on the aging process. This clinical reference addresses the hormonal basis of mental disorders in older people. Hormones influence a wide range of states and conditions, from pain tolerance and anorexia to attention, mood, immunity, cardiovascular and cognitive function, schizophrenia and Alzheimer's disease. Written by an eminent team of psychiatrists, psychologists, geriatricians and neuropharmacologists, this book brings together established information and findings in four sections: • An overview of the basic science of neurosteroids • Sex difference and the roles that cortisol, thyroid hormone, and the sex steroids estrogen, progesterone, dehydroepiandrosterone and testosterone play in common mental disorders and pain sensitivity • Psychoneuroimmunology in relation to age • Sex differences and hormones in psychotropic drug metabolism in the elderly.

Author : James Russell Sowers,James V. Felicetta
Publisher : Lippincott Williams & Wilkins
Page : 368 pages
File Size : 55,6 Mb
Release : 1988
Category : Aging
ISBN : UCAL:B5036472

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The Endocrinology of Aging by James Russell Sowers,James V. Felicetta Pdf

Author : Robert Benjamin Greenblatt
Publisher : Unknown
Page : 264 pages
File Size : 55,9 Mb
Release : 1978
Category : Medical
ISBN : UOM:39015072234969

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Geriatric Endocrinology by Robert Benjamin Greenblatt Pdf