Endocrine Immunology

Author : W. Savino,F. Guaraldi
Publisher : Karger Medical and Scientific Publishers
Page : 180 pages
File Size : 40,8 Mb
Release : 2017-02-28
Category : Medical
ISBN : 9783318060140

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Endocrine Immunology by W. Savino,F. Guaraldi Pdf

In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.

Author : A.M. McGregor
Publisher : Springer Science & Business Media
Page : 208 pages
File Size : 45,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400941717

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Immunology of Endocrine Diseases by A.M. McGregor Pdf

Nineteen eighty-six is a most appropriate year in which to be writing about developments in the organ-specific, autoimmune endocrine diseases. It celebrates the publication 30 years ago in 1956 of the classic papers of Roitt and Doniach and their co-workers I , and of Rose and Witebsky2 and Adams 3 and Purves . These three sets of fundamental observations provided the initial building blocks upon which much of what has been established in the field in the last 30 years was built. No publication of this nature on endocrine autoimmune disease can cover every aspect of the subject. I have chosen to highlight the organs (thyroid and pancreeas) which have attracted the most attention, and the areas of work within these fields within which most research effort is currently focused. There are still some gaps; the insulin and TSH receptors are not considered, nor in any detail are the role of cytotoxic mechanisms in mediating gland destruction. Molecular biology will undoubtedly in the next few years clarify once and for all the controversy that surrounds the structure of the TSH receptor and T cell cloning, the role of cell-mediated cytotoxicity. The pathogenetic mechanisms underlying autoimmunity are increasingly well understood and the search for the aetiology has begun.

Author : S. Freier
Publisher : CRC Press
Page : 278 pages
File Size : 54,9 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351085649

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The Neuroendocrine Immune Network by S. Freier Pdf

This informative publication updates the study of interaction of the nervous and endocrine systems with the immune system in the body. It describes the anatomical basis of these interactions, reviewing the innervation of lymphoid tissue and mast cells. The book discusses the effect of the endocrine system on immune function, including the relation of sex to the immune response. Emphasis is given to opioids, substance P, neurotensin, vasoactive intestinal peptide, somatostatin and cholecystokinin. Also addressed is the immunoregulatory effect of leukotrienes and platelet-activating factors. Scrutinized within are stress as an aspect of neuro-immune interactions, and the central role of the hypothalamus in this context. The book reviews the eye and the gastrointestinal tract with respect to the coordination of the nervous, endocrine, and immune systems in serving these organs. This work is of particular value to those in immunology, endocrinology, gastroenterology, and developmental biology.

Author : Rolf C. Gaillard
Publisher : Karger Medical and Scientific Publishers
Page : 144 pages
File Size : 43,6 Mb
Release : 2002
Category : Medical
ISBN : 9783805572828

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Neuroendocrine-immune Interactions by Rolf C. Gaillard Pdf

Interactions between the immune, endocrine and nervous systems seldom appear as main issues in the neurosciences and in immunology. So far this was most likely due to the need to focus on the molecular and cellular bases of single neural, endocrine and immune processes. But hormones, neurotransmitters and neuropeptides can also influence more subtle mechanisms underlying immune cell activity. The contents of this volume aim at listing some aspects which show that not only the bases for neuroendocrine control of more refined mechanisms related to the organization and functioning of the immune systems to exist, but also that the immune system can actively communicate with neuroendocrine structures. The evidence is divided into three categories: - Anatomical, cellular and molecular bases for the exchange of information between immune, endocrine and neural cells, - reciprocal effects between immune and neuroendocrine mechanisms, and - immune-neuroendocrine regulatory circuits. Immunologically triggered neuroendocrine responses can be either beneficial or deleterious for the host. A systematic approach would imply the simultaneous evaluation of neuroendocrine and immune parameters and thus provide the basis for therapeutic interventions based on antagonizing or blocking undesirable effects.

Author : George S. Eisenbarth
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 54,8 Mb
Release : 2010-12-13
Category : Medical
ISBN : 9781603274784

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Immunoendocrinology: Scientific and Clinical Aspects by George S. Eisenbarth Pdf

Immunoendocrinology is a rapidly developing field of research that seeks to understand the intersection of the immune and endocrine systems. Immunoendocrinology: Scientific and Clinical Aspects explores in detail the current knowledge of immunoendocrinology, namely endocrine disorders produced by disorders of immune function. Chapters cover both basic pathophysiology informed by studies of animal models as well as current understanding of multiple related clinical diseases—their pathophysiology, diagnosis, and therapy. Immunoendocrinology: Scientific and Clinical Aspects captures the central role of immunoendocrinologic processes in the pathogenesis of not only type 1 diabetes but in a range of other autoimmune and endocrine disorders.

Author : Charles J. Grossman
Publisher : Springer Science & Business Media
Page : 227 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461226161

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Bilateral Communication Between the Endocrine and Immune Systems by Charles J. Grossman Pdf

Bilateral Communication Between the Endocrine and Immune Systems, Volume 7 in the Springer-Verlag Endocrinology and Metabolism Series, offers the most current information and recent advances in the area of communication and regulation between the Immune and Endocrine Systems. Immune-Endocrine Interactions are reported to play pivotal roles in both activation and down-regulation of immune responses and this volume provides the most up-to-date research and findings on the immune-endocrine relationship. The contributing authors are internationally recognized experts in this area and have written chapters on such diverse topics as Interactions between the Pituitary and Immune Systems, Effects of Estrogens and Androgens on Immune Response, The Role of Sex Steroids in Immune System Regulation, and Neuroendocrine and Thymus Interactions During Development and Aging. This volume is a must for all endocrinologists and endocrinology residents.

Author : Robert Ader
Publisher : Academic Press
Page : 2582 pages
File Size : 46,7 Mb
Release : 2007
Category : Medical
ISBN : 9780120885770

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Psychoneuroimmunology by Robert Ader Pdf

Psychoneuroimmunology is the study of interactions among behavioral, neural and endocrine, and immunologic processes of adaptation. These two volumes provide a clearly written, extensively referenced summary of some of the behavioral, neural and endocrine regulators of immune responses and immunologically mediated disease processes and of the behavioral and neuroendocrine effects of immune system activity. Several chapters expand upon topics reviewed in earlier editions of this series; most chapters cover active areas of research that have not previously been reviewed. As illustrated in this fourth edition, interdisciplinary research continues to provide evidence that the brain and immune system represent a single, integrated system of defense.

Author : A M McGregor
Publisher : Unknown
Page : 222 pages
File Size : 52,8 Mb
Release : 1986-06-30
Category : Electronic
ISBN : 9400941722

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Immunology of Endocrine Diseases by A M McGregor Pdf

Author : R. Volpe
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642816246

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Auto-immunity in the Endocrine System by R. Volpe Pdf

The present monograph will concern itself with those disorders of the endocrine system, either associated with destruction, interference with function or hyper function, which are considered to be due to auto-immune processes. Endocrinopathies Non-endocrine auto-immune disorders associated with the endocrinopathies Graves' (Basedow's, Parry's) disease Pernicious anaemia Hashimoto's thyroiditis Vitiligo Idiopathic Addison's disease Myaesthenia gravis Insulinopenic diabetes mellitus Sjogren's syndrome Auto-immune oophoritis and orchitis Rheumatoid arthritis Auto-immune hypoparathyroidism Idiopathic thrombocytopenic purpura Auto-immune hypophysitis Chronic active hepatitis Possibly some cases of infertility Primary biliary cirrhosis due to anti-sperm antibodies Reproduced with permission from Volpe (1977) The above table indicates those organ-specific endocrinopathies considered to be due to auto-immune factors, as well as those non-endocrine, organ-specific auto-immune disorders which may be associated with them (Volpe 1977). It is evident that such disorders, occurring without any obvious external cause, raise the very elementary question of how immune processes directed against self constituents could be initiated. Generally, of course, the immune system acts as a regulatory and defence mechanism, and disorders of auto-immunity represent breakdowns in this regulatory system. The following chapters will be concerned with the individual components ofthe endocrine system so affected by auto-immune processes; it will first be necessary to provide an initial chapter for the purpose of summarizing some general principles of immunology, in order to place the immune disorders of the endocrine system in context.

Author : A.P. Weetman
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401150446

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Endocrine Autoimmunity and Associated Conditions by A.P. Weetman Pdf

Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.

Author : Anthony P. Weetman
Publisher : CUP Archive
Page : 336 pages
File Size : 49,7 Mb
Release : 1991-12-19
Category : Medical
ISBN : 0521401615

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Autoimmune Endocrine Disease by Anthony P. Weetman Pdf

Author : Francesco Bottaccioli,Anna Giulia Bottaccioli
Publisher : Unknown
Page : 736 pages
File Size : 55,6 Mb
Release : 2020
Category : Medical
ISBN : 882144922X

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Psychoneuroendocrinoimmunology and the Science of Integrated Medical Treatment. The Manual by Francesco Bottaccioli,Anna Giulia Bottaccioli Pdf

Author : Jorge H. Daruna
Publisher : Academic Press
Page : 336 pages
File Size : 49,5 Mb
Release : 2012-02-24
Category : Medical
ISBN : 9780123820495

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Introduction to Psychoneuroimmunology by Jorge H. Daruna Pdf

Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, Second Edition, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader. Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others Expanded use of figures, tables, and text boxes

Author : Anthony P. Weetman
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 44,9 Mb
Release : 2007-12-26
Category : Medical
ISBN : 9781597455176

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Autoimmune Diseases in Endocrinology by Anthony P. Weetman Pdf

This is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The first section details the basic mechanism of autoimmunity and examines immunogenetic and environmental factors in autoimmunity. The next section examines autoimmune thyroid disease. The third section takes a look at Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies.

Author : C. Jane Welsh,Mary Meagher,Esther Sternberg
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 47,5 Mb
Release : 2007-04-05
Category : Medical
ISBN : 9780387483344

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Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity by C. Jane Welsh,Mary Meagher,Esther Sternberg Pdf

This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense. The discussion includes such topics and stress induced modulation of innate resistance and adaptive immunity in influenza viral infections.