Endothelial Biomedicine

Author : William C. Aird
Publisher : Cambridge University Press
Page : 25 pages
File Size : 44,5 Mb
Release : 2007-09-03
Category : Science
ISBN : 9781139465878

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Endothelial Biomedicine by William C. Aird Pdf

The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all areas of the human body. Clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. The endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume bridges the bench-to-bedside gap in endothelial biomedicine, advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. It's interdisciplinary approach, which draws on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.

Author : Shauna Dauphinee,Aly Karsan
Publisher : Springer Science & Business Media
Page : 234 pages
File Size : 46,7 Mb
Release : 2010-09-24
Category : Medical
ISBN : 9783034601689

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Endothelial Dysfunction and Inflammation by Shauna Dauphinee,Aly Karsan Pdf

Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in inflammatory pathologies, endothelial dysfunction in inflammatory diseases, such as diabetes and atherosclerosis and Clinical methods used to assess endothelial function. This book brings together basic and clinical research to assist the reader in bridging connections from bench-to-bedside. Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession.

Author : William C. Aird
Publisher : CRC Press
Page : 508 pages
File Size : 42,6 Mb
Release : 2005-02-28
Category : Medical
ISBN : 9781135534608

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Endothelial Cells in Health and Disease by William C. Aird Pdf

This reference serves as the first source to gather current data from endothelial cell biologists in various disciplines to summarize recent progress in the field-providing a complete understanding of the endothelium in health and disease and demonstrating its potential as a therapeutic target.

Author : Shampa Chatterjee
Publisher : Academic Press
Page : 279 pages
File Size : 48,6 Mb
Release : 2021-01-20
Category : Science
ISBN : 9780128163825

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Endothelial Signaling in Vascular Dysfunction and Disease by Shampa Chatterjee Pdf

Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease. Discusses the most relevant discoveries in endothelial biology and their link to manifestations of clinical disease Presents history and diagrams in each section to highlight the original biological discovery and its link of clinical manifestations of vascular disease Includes recent findings on the relationship between endothelial signaling, chemotherapy and radiation induced endothelial dysfunction

Author : Elena I. Ryabchikova
Publisher : MDPI
Page : 472 pages
File Size : 40,6 Mb
Release : 2021-09-01
Category : Medical
ISBN : 9783036508689

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Advances in Nanomaterials in Biomedicine by Elena I. Ryabchikova Pdf

"Advances in Nanomaterials in Biomedicine" provided a platform for more than 110 researchers from different countries to present their latest investigations in various fields of nanotechnology, new methods and nanomaterials intended for medical applications. Modern achievements in the field of nanoparticle-based diagnostics, drug delivery and the use of various nanomaterials in the treatment of diseases are presented in 11 original articles. The published reviews provide a comprehensive analysis of the current information on the use of nanomedicine in the treatment and diagnosis of cancer and liver fibrosis, in the field of solid tissue engineering and in drug delivery systems.

Author : E. Abraham,Mervyn Singer
Publisher : Springer Science & Business Media
Page : 476 pages
File Size : 47,8 Mb
Release : 2007-08-27
Category : Medical
ISBN : 3540301585

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Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery by E. Abraham,Mervyn Singer Pdf

There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.

Author : Tommaso Angelone,Maria Carmela Cerra,Bruno Tota
Publisher : Springer
Page : 267 pages
File Size : 50,9 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9783319583389

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Chromogranins: from Cell Biology to Physiology and Biomedicine by Tommaso Angelone,Maria Carmela Cerra,Bruno Tota Pdf

The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions. The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.

Author : Sashwati Roy,Debasis Bagchi,Siba P. Raychaudhuri
Publisher : CRC Press
Page : 472 pages
File Size : 48,7 Mb
Release : 2012-09-17
Category : Medical
ISBN : 9781439872154

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Chronic Inflammation by Sashwati Roy,Debasis Bagchi,Siba P. Raychaudhuri Pdf

Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts: Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution. Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role. Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens. Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.

Author : Alan D. Michelson
Publisher : Elsevier
Page : 1386 pages
File Size : 47,5 Mb
Release : 2011-08-29
Category : Medical
ISBN : 9780080465869

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Platelets by Alan D. Michelson Pdf

Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. First edition won Best Book in Medical Science Award from the Association of American Publishers Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references

Author : Bin Ren,Xiaofeng Yang,Ramani Ramchandran
Publisher : Frontiers Media SA
Page : 332 pages
File Size : 50,6 Mb
Release : 2022-02-02
Category : Science
ISBN : 9782889742523

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Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity by Bin Ren,Xiaofeng Yang,Ramani Ramchandran Pdf

Author : Gianni Ciofani
Publisher : Elsevier
Page : 268 pages
File Size : 41,8 Mb
Release : 2018-05-12
Category : Technology & Engineering
ISBN : 9780128141571

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Smart Nanoparticles for Biomedicine by Gianni Ciofani Pdf

Smart Nanoparticles for Biomedicine explores smart nanoparticles that change their structural or functional properties in response to specific external stimuli (electric or magnetic fields, electromagnetic radiation, ultrasound, etc.). Particular attention is given to multifunctional nanostructured materials that are pharmacologically active and that can be actuated by virtue of their magnetic, dielectric, optically-active, redox-active, or piezoelectric properties. This important reference resource will be of great value to readers who want to learn more on how smart nanoparticles can be used to create more effective treatment solutions. Nanotechnology has enabled unprecedented control of the interactions between materials and biological entities, from the microscale, to the molecular level. Nanosurfaces and nanostructures have been used to mimic or interact with biological microenvironments, to support specific biological functions, such as cell adhesion, mobility and differentiation, and in tissue healing. Recently, a new paradigm has been proposed for nanomedicine to exploit the intrinsic properties of nanomaterials as active devices rather than as passive structural units or carriers for medications. Discusses the synthesis, characterization and applications of a new generation of smart nanoparticles for nanomedicine applications Explores the problems relating to the biocompatibility of a range of nanoparticles, outlining potential solutions Describes techniques for manipulating specific classes of nanoparticles for a variety of treatment types

Author : Young-Wook Kim,Byung-Boong Lee,Wayne F. Yakes,Young-Soo Do
Publisher : Springer
Page : 382 pages
File Size : 52,8 Mb
Release : 2017-10-14
Category : Medical
ISBN : 9783662467091

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Congenital Vascular Malformations by Young-Wook Kim,Byung-Boong Lee,Wayne F. Yakes,Young-Soo Do Pdf

This book is a superbly illustrated guide to the diagnosis and treatment of congenital vascular malformations (CVMs) that will enable the reader to avoid the serious pitfalls that may arise when caring for patients with this rare and complex group of lesions. After discussion of pathogenesis, classification, and differential diagnosis from vascular tumors, the clinical features of CVMs are described and illustrated, covering both the various forms (venous, arteriovenous, lymphatic, capillary, and mixed) and presentations at different anatomic sites. The current role of CT, MRI, scintigraphy, and angiography in diagnostic evaluation is explained, and treatment options, including conservative treatment, are then considered in detail. The discussion of endovascular treatment, or embolo-sclerotherapy, includes instruction on patient selection, embolic and sclerosing materials, access to the target lesion, site-specific variations in treatment strategy, and complications and their management. Indications for and performance of surgical/excisional therapy and laser therapy are also fully considered.

Author : Tipton, Charles M.
Publisher : Human Kinetics
Page : 1281 pages
File Size : 41,9 Mb
Release : 2014-03-21
Category : Science
ISBN : 9781450482370

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History of Exercise Physiology by Tipton, Charles M. Pdf

Well illustrated with figures and photos, this text brings together leading authorities in exercise physiology to help readers understand the research findings and meet the most prominent professionals in the field.

Author : Anonim
Publisher : Unknown
Page : 260 pages
File Size : 51,9 Mb
Release : 1992
Category : Holography in medicine
ISBN : STANFORD:36105008641552

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Proceedings of Holography, Interferometry, and Optical Pattern Recognition in Biomedicine by Anonim Pdf

Author : Anonim
Publisher : ScholarlyEditions
Page : 137 pages
File Size : 48,6 Mb
Release : 2012-01-09
Category : Science
ISBN : 9781464927713

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Membrane Glycoproteins: Advances in Research and Application: 2011 Edition by Anonim Pdf

Membrane Glycoproteins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Membrane Glycoproteins. The editors have built Membrane Glycoproteins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Membrane Glycoproteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Membrane Glycoproteins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.