Energetics Of Biological Macromolecules

Author : Anonim
Publisher : Elsevier
Page : 581 pages
File Size : 49,7 Mb
Release : 2000-08-09
Category : Science
ISBN : 9780080496788

Get Book

Energetics of Biological Macromolecules, Part C by Anonim Pdf

Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal is to understand the energetic relationships between macromoleculer structures and biological functions. This volume supplements Volumes 259 and Volume 295 of Methods in Enzymology. Key Features * Probing Stability of Helical Transmembrane Proteins * Energetics of Vinca Alkaloid Interactions with Tubulin * Deriving Complex Ligand Binding Formulas * Mathematical Modeling of Cooperative Interactions in Hemoglobin * Analysis of Interactions of Regulatory Protein TyrR with DNA * Parsing Free Energy of Drug-DNA Interactions * Use of Fluorescence as Thermodynamics Tool

Author : Jo M. Holt,Michael L. Johnson,Gary K. Ackers
Publisher : Elsevier
Page : 315 pages
File Size : 41,7 Mb
Release : 2004-04-02
Category : Science
ISBN : 9780080497174

Get Book

Energetics of Biological Macromolecules, Part D by Jo M. Holt,Michael L. Johnson,Gary K. Ackers Pdf

This volume focuses on the cooperative binding aspects of energetics in biological macromolecules. Methodologies such as NMR, small-angle scattering techniques for analysis, calorimetric analysis, fluorescence quenching, and time resolved FRET measurements are discussed. *Methods for Evaluating Cooperativity in a Dimeric Hemoglobin*Multiple-Binding of Ligands to a Linear Biopolymer*Fluorescence Quenching Methods to Study Protein-Nucleic Acid Interactions*Linked Equilibria in Biotin Repressor Function: Thermodynamic, Structural and Kinetic Analysis

Author : Michael L. Johnson,Gary K. Ackers
Publisher : Elsevier
Page : 596 pages
File Size : 53,7 Mb
Release : 1998
Category : Allosteric regulation
ISBN : 012182196X

Get Book

Energetics of Biological Macromolecules by Michael L. Johnson,Gary K. Ackers Pdf

Essential publication for researchers in all fields of life sciences. Key Features * Major topics covered include: * Deciphering rules of helix stability in peptides * Protein Folding in Membranes * Molecular Crowding * Study of the Bohr Effect in Hemoglobin Intermediates * Photoacoustic Calorimetry of Proteins * Theoretical Aspects of Isothermal Titration Calorimetry * Energetic Methods to Study Bifunctional Biotin Repressor.

Author : Anonim
Publisher : Elsevier
Page : 443 pages
File Size : 46,7 Mb
Release : 2004-04-02
Category : Science
ISBN : 9780080497181

Get Book

Energetics of Biological Macromolecules, Part E by Anonim Pdf

Energetics of Biological Macromolecules, Part E focuses on methods related to allosteric enzymes and receptors, including fluorescent proves, spectroscopic methods and quantitative analysis as well as on cooperativity in protein folding. NMR and mass spectrometry methods are discussed. Allosteric Enzymes and Receptors Cooperativity in Protein Folding and Assembly

Author : Anonim
Publisher : Academic Press
Page : 548 pages
File Size : 41,9 Mb
Release : 1998-09-09
Category : Science
ISBN : 012182196X

Get Book

Energetics of Biological Macromolecules by Anonim Pdf

General Description of the Volume: The very existence of biological structures and their functional interactions are dictated by energetic relationships. Thus the central theme of this volume is that thermodynamic methods, i.e. techniques that probe the energetics of biological macromolecules, now comprise a powerful and practical family of tools for research in modern biology. The application of thermodynamics and statistical thermodynamics to biochemical and biophysical systems is presented. This volume supplements Methods in Enzymology, Volume 259. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Major topics covered include: * Deciphering rules of helix stability in peptides * Protein Folding in Membranes * Molecular Crowding * Study of the Bohr Effect in Hemoglobin Intermediates * Photoacoustic Calorimetry of Proteins * Theoretical Aspects of Isothermal Titration Calorimetry * Energetic Methods to Study Bifunctional Biotin Repressor

Author : Jo M. Holt,Michael L. Johnson,Gary K. Ackers
Publisher : Unknown
Page : 443 pages
File Size : 54,9 Mb
Release : 2004
Category : Allosteric enzymes
ISBN : OCLC:54685204

Get Book

Energetics of Biological Macromolecules by Jo M. Holt,Michael L. Johnson,Gary K. Ackers Pdf

Author : John N Abelson
Publisher : Unknown
Page : 128 pages
File Size : 50,7 Mb
Release : 1998
Category : Electronic
ISBN : OCLC:1113723063

Get Book

Energetics of Biological Macromolecules, Part B. by John N Abelson Pdf

Author : Michael L. Johnson
Publisher : Unknown
Page : 0 pages
File Size : 43,7 Mb
Release : 1995
Category : Electronic
ISBN : OCLC:708387911

Get Book

Energetics of Biological Macromolecules by Michael L. Johnson Pdf

Author : Anonim
Publisher : Academic Press
Page : 548 pages
File Size : 55,7 Mb
Release : 1998-09-09
Category : Science
ISBN : 012182196X

Get Book

Energetics of Biological Macromolecules by Anonim Pdf

General Description of the Volume: The very existence of biological structures and their functional interactions are dictated by energetic relationships. Thus the central theme of this volume is that thermodynamic methods, i.e. techniques that probe the energetics of biological macromolecules, now comprise a powerful and practical family of tools for research in modern biology. The application of thermodynamics and statistical thermodynamics to biochemical and biophysical systems is presented. This volume supplements Methods in Enzymology, Volume 259. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Major topics covered include: * Deciphering rules of helix stability in peptides * Protein Folding in Membranes * Molecular Crowding * Study of the Bohr Effect in Hemoglobin Intermediates * Photoacoustic Calorimetry of Proteins * Theoretical Aspects of Isothermal Titration Calorimetry * Energetic Methods to Study Bifunctional Biotin Repressor

Author : Norman W. H. Cheetham
Publisher : OUP Oxford
Page : 352 pages
File Size : 44,5 Mb
Release : 2010-10-08
Category : Science
ISBN : 9780191576768

Get Book

Introducing Biological Energetics by Norman W. H. Cheetham Pdf

This novel, interdisciplinary text presents biological understanding in terms of general underlying principles, treating energy as the overarching theme and emphasizing the all-pervading influence of energy transformation in every process, both living and non-living. Key processes and concepts are explained in turn, culminating in a description of the overall functioning and regulation of a living cell. The book rounds off the story of life with a brief account of the endosymbiotic origins of eukaryotic cells, the development of multicellularity, and the emergence of modern plants and animals. Multidisciplinary research in science is becoming commonplace. However, as traditional boundaries start to break down, researchers are increasingly aware of the deficiencies in their knowledge of related disciplines. Introducing Biological Energetics redresses the reciprocal imbalance in the knowledge levels of physical and biological scientists in particular. Its style of presentation and depth of treatment has been carefully designed to unite these two readerships.

Author : Jeffries Wyman,Stanley J. Gill
Publisher : University Science Books
Page : 358 pages
File Size : 49,9 Mb
Release : 1990
Category : Science
ISBN : 0935702563

Get Book

Binding and Linkage by Jeffries Wyman,Stanley J. Gill Pdf

Ligand-macromolecule interactions are of fundamental importance in the control of biological processes. This book applies the principles of linkage thermodynamics to polyfunctional macromolecular systems under equilibrium conditions, and describes the binding, linkage, and feedback phenomena that lead to control of complex metabolic processes. The first chapter sets out the different processes (conformational changes, changes in state of aggregation, phase changes) involving biological macromolecules which are affected by chemical variables (such as ligands) or physical variables (such as temperature and pressure). The general effects of ligands on micromolecular conformations and interactions are illustrated with specific examples from the respiratory proteins, electron-transport proteins, and nucleic acid binding proteins. Subsequent chapters develop these themes, and describe in detail how the mathematics of regulation and control can be applied to macromolecules in biological system.

Author : Oleg Jardetzky,Michael D. Finucane
Publisher : IOS Press
Page : 212 pages
File Size : 40,5 Mb
Release : 2001
Category : Biomolecules
ISBN : 1586030329

Get Book

Dynamics, Structure, and Function of Biological Macromolecules by Oleg Jardetzky,Michael D. Finucane Pdf

A collection of articles looking at modern structural biology, summarizing the applications of physical methods - such as x-ray diffraction, high resolution nuclear magnetic resonance and molecular dynamics - to the study of protein structure and dynamics. There is a review of contemporary thoughts within the field, looking at the mechanisms of alloateric transitions and allosteric control, the transmission of information within protein structures and the role of dynamics in determining the specificity of protein - ligand interactions. There is also a look at future innovations.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

Get Book

Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Prof. Jan Hermans,Barry Lentz
Publisher : John Wiley & Sons
Page : 411 pages
File Size : 50,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781118733776

Get Book

Equilibria and Kinetics of Biological Macromolecules by Prof. Jan Hermans,Barry Lentz Pdf

Progressively builds a deep understanding of macromolecular behavior Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a solid foundation in the basics by beginning with core physical concepts such as thermodynamics, quantum chemical models, molecular structure and interactions, and water and the hydrophobic effect. Next, the book examines statistical mechanics, protein-ligand binding, and conformational stability. Finally, the authors address kinetics and equilibria, exploring underlying theory, protein folding, and stochastic models. With its strong emphasis on molecular interactions, Equilibria and Kinetics of Biological Macromolecules offers new insights and perspectives on proteins and other macromolecules. The text features coverage of: Basic theory, applications, and new research findings Related topics in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations Principles and applications of molecular simulations in a dedicated chapter and interspersed throughout the text Macromolecular binding equilibria from the perspective of statistical mechanics Stochastic processes related to macromolecules Suggested readings at the end of each chapter include original research papers, reviews and monographs, enabling readers to explore individual topics in greater depth. At the end of the text, ten appendices offer refreshers on mathematical treatments, including probability, computational methods, Poisson equations, and defining molecular boundaries. With its classroom-tested pedagogical approach, Equilibria and Kinetics of Biological Macromolecules is recommended as a graduate-level textbook for biophysics courses and as a reference for researchers who want to strengthen their understanding of macromolecular behavior.

Author : Enrico Di Cera
Publisher : Oxford University Press, USA
Page : 250 pages
File Size : 52,6 Mb
Release : 2000
Category : Medical
ISBN : 0195123271

Get Book

Thermodynamics in Biology by Enrico Di Cera Pdf

Enrico Di Cera, a rising star in biophysics, has organized a superb group of authors to write substantial chapters covering the most exciting and central issues relating to the bioenergetic aspects of proteins, nucleic acids, and their interactions. Topics covered in this book are protein and nucleic acid folding and stability, enzyme-substrate interactions, prediction of the affinity of complexes, electrostatics, and non-equilibrium aspects of protein function. The breadth of the topics covered in this book illustrates the growing importance of thermodynamic approaches in the study of biological phenomena. The book should be of wide interest to biophysicists, biochemists, and structural biologists.