Engineering Of Biomaterials For Drug Delivery Systems

Author : Anilkumar Parambath
Publisher : Woodhead Publishing
Page : 404 pages
File Size : 43,8 Mb
Release : 2018-02-01
Category : Technology & Engineering
ISBN : 9780081017517

Get Book

Engineering of Biomaterials for Drug Delivery Systems by Anilkumar Parambath Pdf

Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field. Provides a self-contained work for the field of biomaterials for drug delivery Summarizes the current knowledge on PEGylation and strategies for bypassing it Presents research on an important, though under-represented issue in biomaterials Written by a world-class team of research scientists, engineers and clinicians

Author : Ali Seyfoddin,Seyedehsara Masoomi Dezfooli,Carol Ann Greene
Publisher : Woodhead Publishing
Page : 252 pages
File Size : 43,8 Mb
Release : 2019-11-15
Category : Technology & Engineering
ISBN : 9780081025499

Get Book

Engineering Drug Delivery Systems by Ali Seyfoddin,Seyedehsara Masoomi Dezfooli,Carol Ann Greene Pdf

Engineering Drug Delivery Systems is an essential resource on a variety of biomaterials engineering approaches for creating drug delivery systems that have market and therapeutic potential. The book comprehensively discusses recent advances in the fields of biomaterials and biomedical sciences in relation to drug delivery. Chapters provide a detailed introduction to various engineering approaches in designing drug delivery systems, delve into the engineering of body functions, cover the selection, design and evaluation of biomaterials, and discuss the engineering of colloids as drug carriers. The book's final chapters address the engineering of implantable drug delivery systems and advances in drug delivery technology. This book is an invaluable resource for drug delivery, materials scientists and bioengineers within the pharmaceutical industry. Examines the properties and synthesis of biomaterials for successful drug delivery Discusses the important connection between drug delivery and tissue engineering Includes techniques and approaches applicable to a wide range of users Reviews innovative technologies in drug delivery systems such as 3-D printed devices for drug delivery

Author : Naoya Ogata,Sung W. Kim,Jan Feijen,Teruo Okano
Publisher : Springer Science & Business Media
Page : 395 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9784431658832

Get Book

Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems by Naoya Ogata,Sung W. Kim,Jan Feijen,Teruo Okano Pdf

First of all, I would like to share the great pleasure of the successful five-day symposium with every participant in the 5th Iketani Conference which was held in Kagoshima from April1S (Tuesday) to 22 (Saturday), 1995. Outstanding speakers enthusiastically presented their up-to-the-minute results. Relatively little time was allotted for each presentation to ensure asdnuch time· as possible for intensive discussions on the particular topics that had just been p~esented: I was delighted to see that the lectures were of high quality, and the discu,ssionswere lively, exciting, and productive in a congenial atmosphere. We also had 92 papers in the poster ·session, in which young (and relatively young) scientists made every effort to present the novel results of their research in advanced biomaterials and drug delivery systems (DDS). I believe some of the research is most promising and will become noteworthy in the twenty-first century. It was a privilege for me to deliver a lecture at the special session of the symposium. In my introductory remarks, I pointed out five key terms in multifaceted biomaterials research: materials design, concept or methodology, devices, properties demanded, and fundamentals. I am confident that innovative progress in device manufacturing for end-use, e.g., artificial organs, vascular grafts, and DDS, can be brought about only through properly designed advanced materials that exhibit the desired functionality at the interface with any living body.

Author : Rebecca A. Bader,David A. Putnam
Publisher : John Wiley & Sons
Page : 395 pages
File Size : 48,5 Mb
Release : 2014-01-17
Category : Social Science
ISBN : 9781118747803

Get Book

Engineering Polymer Systems for Improved Drug Delivery by Rebecca A. Bader,David A. Putnam Pdf

Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Author : Lisa C. du Toit,Pradeep Kumar,Yahya E. Choonara,Viness Pillay
Publisher : Elsevier
Page : 318 pages
File Size : 48,5 Mb
Release : 2020-03-08
Category : Technology & Engineering
ISBN : 9780128184721

Get Book

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering by Lisa C. du Toit,Pradeep Kumar,Yahya E. Choonara,Viness Pillay Pdf

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient Explores the current generation of nanostructured 3D printed medical devices Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

Author : Eric P. Holowka,Sujata K. Bhatia
Publisher : Springer
Page : 355 pages
File Size : 43,7 Mb
Release : 2014-11-22
Category : Technology & Engineering
ISBN : 9781493919987

Get Book

Drug Delivery by Eric P. Holowka,Sujata K. Bhatia Pdf

Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments. Drug Delivery: Materials Design and Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on “Engineering Concepts” reviews the relevant fundamental principles that guide rational design. The following section on “Materials Design” discusses how the design process applies engineering concepts for use in physiological systems. A third section on “Implementation” discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on “Clinical Applications” which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. · Provides a comprehensive description of drug delivery systems from a materials perspective · Includes a wide-ranging discussion of clinical applications of drug delivery systems · Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. · Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material type

Author : Michael J. Yaszemski,Debra J. Trantolo,Kai-Uwe Lewandrowski,Vasif Hasirci,David E. Altobelli,Donald L. Wise
Publisher : CRC Press
Page : 654 pages
File Size : 43,9 Mb
Release : 2003-11-04
Category : Medical
ISBN : 9780203913338

Get Book

Tissue Engineering And Novel Delivery Systems by Michael J. Yaszemski,Debra J. Trantolo,Kai-Uwe Lewandrowski,Vasif Hasirci,David E. Altobelli,Donald L. Wise Pdf

Essential to anyone working in the field, this reference focuses on latest advancements in tissue construction, repair and regeneration focusing on developments in gene and drug therapy, the evolution of tissue-engineered products, and new technologies for the design of functional tissues and organ systems.

Author : Rajakumari Rajendran,Hanna J. Maria,Sabu Thomas,Nandakumar Kalarikkal
Publisher : CRC Press
Page : 650 pages
File Size : 53,8 Mb
Release : 2022-03-10
Category : Science
ISBN : 9781000369533

Get Book

Handbook of Research on Nano-Drug Delivery and Tissue Engineering by Rajakumari Rajendran,Hanna J. Maria,Sabu Thomas,Nandakumar Kalarikkal Pdf

With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 514 pages
File Size : 50,8 Mb
Release : 2017-03-27
Category : Medical
ISBN : 9780323527286

Get Book

Nano- and Microscale Drug Delivery Systems by Alexandru Mihai Grumezescu Pdf

Nano- and Microscale Drug Delivery Systems: Design and Fabrication presents the developments that have taken place in recent years in the field of micro- and nanoscale drug delivery systems. Particular attention is assigned to the fabrication and design of drug delivery systems in order to i) reduce the side effects of therapeutic agents, ii) increase their pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. This book is designed to offer a cogent, concise overview of current scholarship in this important area of research through its focus on the characterization and fabrication of a variety of nanomaterials for drug delivery applications. It is an invaluable reference source for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems. Shows how micro- and nanomaterials can be engineered to create more effective drug delivery systems Summarizes current nanotechnology research in the field of drug delivery systems Explores the pros and cons of using particular nanomaterials as therapeutic agents Serves as a valuable reference for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems

Author : W. Mark Saltzman
Publisher : Oxford University Press
Page : 384 pages
File Size : 51,5 Mb
Release : 2001-03-15
Category : Medical
ISBN : 9780199879755

Get Book

Drug Delivery by W. Mark Saltzman Pdf

Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

Author : Sougata Jana,Subrata Jana
Publisher : Springer Nature
Page : 524 pages
File Size : 41,8 Mb
Release : 2022-03-29
Category : Science
ISBN : 9789811671524

Get Book

Functional Biomaterials by Sougata Jana,Subrata Jana Pdf

This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.

Author : Sougata Jana,Subrata Jana
Publisher : Springer Nature
Page : 420 pages
File Size : 42,6 Mb
Release : 2023-01-31
Category : Science
ISBN : 9789811969379

Get Book

Alginate Biomaterial by Sougata Jana,Subrata Jana Pdf

This book focuses on recent trends of research on alginate-based biomaterials in Drug Delivery strategies and biomedical engineering. It contains the widely used alginate-based biomaterials as micro to nano-controlled drug delivery (oral, ocular delivery, topical delivery, etc.) and its fabrication technology, characterization, and biomedical aspects (such as cancer therapy, tissue engineering, gene delivery, vaccine delivery, enzyme immobilization, wound healing, dental applications, etc.) in a single book. The chapters cover updated information, current research trends, informatics, and all aspects of applications. Alginate is a U.S. Food and Drug Administration (FDA)-approved natural biomaterial and has diverse biomedical applications. In recent years, researchers and scientists are working on the alginate-based drug delivery systems that have been designed and characterized as a matrix, micro to nanocarriers, fibers, composite/scaffolds, etc. Alginate has versatile properties such as biodegradable, biocompatible, nontoxic, and easily available. This book especially highlights both the drug delivery strategies and biomedical engineering aspects such as controlled drug delivery, drug targeting to the site of action, cancer therapy, gene and vaccine delivery, enzyme immobilization, tissue engineering, and regenerative medicine.

Author : Eric P. Holowka,Sujata K. Bhatia
Publisher : Unknown
Page : 376 pages
File Size : 52,8 Mb
Release : 2014-12-31
Category : Electronic
ISBN : 1493919997

Get Book

Drug Delivery by Eric P. Holowka,Sujata K. Bhatia Pdf

Author : Yitzhak Rosen,Pablo Gurman,Noel Elman
Publisher : CRC Press
Page : 602 pages
File Size : 54,6 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781466565951

Get Book

Drug Delivery by Yitzhak Rosen,Pablo Gurman,Noel Elman Pdf

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterials, NEMS and MEMS devices, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound. The book is rounded out by a chapter on the FDA regulatory and bioethical challenges involved in advancing drug delivery.

Author : Alexandru Grumezescu,Alina-Maria Holban
Publisher : Elsevier
Page : 616 pages
File Size : 41,6 Mb
Release : 2019-06-18
Category : Medical
ISBN : 9780128184349

Get Book

Materials for Biomedical Engineering: Organic Micro and Nanostructures by Alexandru Grumezescu,Alina-Maria Holban Pdf

Materials for Biomedical Engineering: Organic Micro- and Nanostructures provides an updated perspective on recent research regarding the use of organic particles in biomedical applications. The different types of organic micro- and nanostructures are discussed, as are innovative applications and new synthesis methods. As biomedical applications of organic micro- and nanostructures are very diverse and their impact on modern and future therapy, diagnosis and prophylaxis of diseases is huge, this book presents a timely resource on the topic. Users will find the latest information on cancer and gene therapy, diagnosis, drug delivery, green synthesis of nano- and microparticles, and much more. Provides knowledge of the range of organic micro- and nanostructures available, enabling the reader to make optimal materials selection decisions Presents detailed information on current and proposed applications of the latest biomedical materials Places a strong emphasis on the characterization, production and use of organic nanoparticles in biomedicine, such as gene therapy, DNA interaction and cancer management