Engineering Polymer Systems For Improved Drug Delivery

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Engineering Polymer Systems for Improved Drug Delivery

Author : Rebecca A. Bader,David A. Putnam
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 48,7 Mb
Release : 2014-01-17
Category : Social Science
ISBN : 9781118747803

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Engineering Polymer Systems for Improved Drug Delivery by Rebecca A. Bader,David A. Putnam Pdf

Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Engineering Polymer Systems for Improved Drug Delivery

Author : Rebecca A. Bader,David A. Putnam
Publisher : Wiley
Page : 496 pages
File Size : 44,6 Mb
Release : 2013-12-27
Category : Social Science
ISBN : 1118747941

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Engineering Polymer Systems for Improved Drug Delivery by Rebecca A. Bader,David A. Putnam Pdf

Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Engineering of Biomaterials for Drug Delivery Systems

Author : Anilkumar Parambath
Publisher : Woodhead Publishing
Page : 404 pages
File Size : 55,8 Mb
Release : 2018-02-01
Category : Technology & Engineering
ISBN : 9780081017517

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Engineering of Biomaterials for Drug Delivery Systems by Anilkumar Parambath Pdf

Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field. Provides a self-contained work for the field of biomaterials for drug delivery Summarizes the current knowledge on PEGylation and strategies for bypassing it Presents research on an important, though under-represented issue in biomaterials Written by a world-class team of research scientists, engineers and clinicians

Drug Delivery

Author : W. Mark Saltzman
Publisher : Oxford University Press
Page : 384 pages
File Size : 42,5 Mb
Release : 2001-03-15
Category : Medical
ISBN : 9780199879755

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Drug Delivery by W. Mark Saltzman Pdf

Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra,Aliasgar Shahiwala
Publisher : Elsevier
Page : 594 pages
File Size : 55,6 Mb
Release : 2020-10-02
Category : Technology & Engineering
ISBN : 9780128226681

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Applications of Polymers in Drug Delivery by Ambikanandan Misra,Aliasgar Shahiwala Pdf

Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. Explains how polymers can be prepared and utilized for all major drug delivery routes Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Fundamentals of Drug Delivery

Author : Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Publisher : John Wiley & Sons
Page : 580 pages
File Size : 50,6 Mb
Release : 2021-10-12
Category : Medical
ISBN : 9781119769606

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Fundamentals of Drug Delivery by Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang Pdf

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Engineering Drug Delivery Systems

Author : Ali Seyfoddin,Seyedehsara Masoomi Dezfooli,Carol Ann Greene
Publisher : Woodhead Publishing
Page : 252 pages
File Size : 42,9 Mb
Release : 2019-11-15
Category : Technology & Engineering
ISBN : 9780081025499

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Engineering Drug Delivery Systems by Ali Seyfoddin,Seyedehsara Masoomi Dezfooli,Carol Ann Greene Pdf

Engineering Drug Delivery Systems is an essential resource on a variety of biomaterials engineering approaches for creating drug delivery systems that have market and therapeutic potential. The book comprehensively discusses recent advances in the fields of biomaterials and biomedical sciences in relation to drug delivery. Chapters provide a detailed introduction to various engineering approaches in designing drug delivery systems, delve into the engineering of body functions, cover the selection, design and evaluation of biomaterials, and discuss the engineering of colloids as drug carriers. The book's final chapters address the engineering of implantable drug delivery systems and advances in drug delivery technology. This book is an invaluable resource for drug delivery, materials scientists and bioengineers within the pharmaceutical industry. Examines the properties and synthesis of biomaterials for successful drug delivery Discusses the important connection between drug delivery and tissue engineering Includes techniques and approaches applicable to a wide range of users Reviews innovative technologies in drug delivery systems such as 3-D printed devices for drug delivery

Organic Materials as Smart Nanocarriers for Drug Delivery

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 768 pages
File Size : 41,7 Mb
Release : 2018-03-26
Category : Science
ISBN : 9780128136645

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Organic Materials as Smart Nanocarriers for Drug Delivery by Alexandru Mihai Grumezescu Pdf

Organic Materials as Smart Nanocarriers for Drug Delivery presents the latest developments in the area of organic frameworks used in pharmaceutical nanotechnology. An up-to-date overview of organic smart nanocarriers is explored, along with the different types of nanocarriers, including polymeric micelles, cyclodextrins, hydrogels, lipid nanoparticles and nanoemlusions. Written by a diverse range of international academics, this book is a valuable reference for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of organic smart nanocarriers. Explores the most recent molecular- and structure-based applications of organic smart nanocarriers in drug delivery Highlights different smart nanocarriers and assesses their intricate organic structural properties for improving drug delivery Assesses how molecular organic frameworks lead to more effective drug delivery systems

Advances in Polymeric Systems for Drug Delivery

Author : Raymond Bonnett
Publisher : CRC Press
Page : 170 pages
File Size : 51,5 Mb
Release : 2002-03-07
Category : Technology & Engineering
ISBN : 2881249477

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Advances in Polymeric Systems for Drug Delivery by Raymond Bonnett Pdf

This title examines new drug delivery strategies utilizing intelligent polymeric materials that perform sensing, processing and response functions. The authors demonstrate the design of polymers with integrated intelligent functions to achieve site specific and temporally controlled drug delivery, specifically for pharmaceutical applications. Using stimuli-responsive polymers as molecular devices for self-regulation and externally modulated drug delivery systems are reviewed from multi-disciplinary perspectives, employing materials science and bio-engineering as an important foundation.

Polymeric Drug Delivery Systems

Author : Glen S. Kwon
Publisher : CRC Press
Page : 680 pages
File Size : 55,9 Mb
Release : 2005-04-12
Category : Medical
ISBN : 0824725328

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Polymeric Drug Delivery Systems by Glen S. Kwon Pdf

Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Polymeric Drugs and Drug Delivery Systems

Author : Raphael M. Ottenbrite,Sung Wan Kim
Publisher : CRC Press
Page : 332 pages
File Size : 52,5 Mb
Release : 2019-04-30
Category : Science
ISBN : 1420010255

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Polymeric Drugs and Drug Delivery Systems by Raphael M. Ottenbrite,Sung Wan Kim Pdf

Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

Design of Controlled Release Drug Delivery Systems

Author : Xiaoling Li
Publisher : McGraw Hill Professional
Page : 453 pages
File Size : 53,6 Mb
Release : 2005-11-24
Category : Technology & Engineering
ISBN : 9780071588836

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Design of Controlled Release Drug Delivery Systems by Xiaoling Li Pdf

The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Drug Delivery

Author : Yitzhak Rosen,Pablo Gurman,Noel Elman
Publisher : CRC Press
Page : 602 pages
File Size : 44,7 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781466565951

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Drug Delivery by Yitzhak Rosen,Pablo Gurman,Noel Elman Pdf

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterials, NEMS and MEMS devices, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound. The book is rounded out by a chapter on the FDA regulatory and bioethical challenges involved in advancing drug delivery.

Multicomponent Transport in Polymer Systems for Controlled Release

Author : Alexandre Ya Polishchuk,Gennadiĭ Efremovich Zaikov
Publisher : CRC Press
Page : 254 pages
File Size : 40,5 Mb
Release : 1997
Category : Science
ISBN : 9056995936

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Multicomponent Transport in Polymer Systems for Controlled Release by Alexandre Ya Polishchuk,Gennadiĭ Efremovich Zaikov Pdf

This book addresses the general aspects of current knowledge of multicomponent transport in hydrophylic and moderately hydrophylic polymers. The first part of the book presents the physical and mathematical models which have been developed in order to predict the behavior of systems consisting of polymer, water and low-molecular solutes. The second half addresses different transport devices for controlled delivery and how the principles reported in the first part could be applied to the regulations of kinetics and the rate of transport of water and solutes. Major applications of polymer systems for controlled release in medicine, agriculture, and in industry are also described.

Fundamentals and Applications of Controlled Release Drug Delivery

Author : Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 41,6 Mb
Release : 2011-12-15
Category : Medical
ISBN : 9781461408819

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Fundamentals and Applications of Controlled Release Drug Delivery by Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone Pdf

This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.