Enzyme Kinetics And Mechanism Part D

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 43,7 Mb
Release : 1995
Category : Electronic
ISBN : OCLC:760664062

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Enzyme Kinetics and Mechanism Part D by Anonim Pdf

Author : Paul F. Cook,W. W. Cleland
Publisher : Garland Science
Page : 416 pages
File Size : 52,7 Mb
Release : 2007-03-06
Category : Medical
ISBN : 9781136844287

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Enzyme Kinetics and Mechanism by Paul F. Cook,W. W. Cleland Pdf

Enzyme Kinetics and Mechanism is a comprehensive textbook on steady-state enzyme kinetics. Organized according to the experimental process, the text covers kinetic mechanism, relative rates of steps along the reaction pathway, and chemical mechanism—including acid-base chemistry and transition state structure. Practical examples taken from the literature demonstrate theory throughout. The book also features numerous general experimental protocols and how-to explanations for interpreting kinetic data. Written in clear, accessible language, the book will enable graduate students well-versed in biochemistry to understand and describe data at the fundamental level. Enzymologists and molecular biologists will find the text a useful reference.

Author : Kenneth B. Taylor
Publisher : Springer Science & Business Media
Page : 237 pages
File Size : 47,6 Mb
Release : 2007-05-08
Category : Science
ISBN : 9780306480256

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Enzyme Kinetics and Mechanisms by Kenneth B. Taylor Pdf

Enzyme Kinetics and Mechanisms takes the reader through the experimental techniques and the logic by which the mechanisms of enzyme-catalyzed reactions can be elucidated by the results of steady-state kinetics and related experiments. It is meant to make these investigations both satisfying and effective. In distinction to other available descriptions, the descriptions in enzyme Kinetics and Mechanisms are limited to more commonly utilized and useful models and techniques. The logic relating the chemical models to the mathematical models and the logic of relating the mathematical models to data is presented in rather concise text, figures and equations. The development of mathematical models from chemical models is done by a unique algorithm that is both simple and quick, and the same concept are utilized to develop models for the effects of a variety of reaction conditions on the initial velocity. In addition, the various relationships of data, mathematical models and the chemical models is illustrated with examples from the scientific literature.

Author : Daniel L. Purich
Publisher : Academic Press
Page : 567 pages
File Size : 41,5 Mb
Release : 1983-01-01
Category : Science
ISBN : 9781483214221

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Contemporary Enzyme Kinetics and Mechanism by Daniel L. Purich Pdf

Selected Methods in Enzymology: Contemporary Enzyme Kinetics and Mechanism provides an introduction to enzyme kinetics and mechanism at an intermediate level. This book covers a variety of topics, including temperature effects in enzyme kinetics, cryoenzymology, substrate inhibition, enol intermediates enzymology, and heavy-atom isotope effects. Organized into 19 chapters, this book begins with an overview of derivation of rate equations as an integral part of the effective usage of kinetics as a tool. This text then examines the practical aspects of initial rate enzyme assay. Other chapters consider the basic procedures used in making decisions concerning kinetic mechanisms from initial-rate data. This book discusses as well the various aspects of both the theoretical background and the applications. The final chapter deals with the importance of achieving proficiency in formulating quantitative relationships describing enzyme behavior. This book is a valuable resource for students and research workers. Enzymologists and chemists will also find this book useful.

Author : Anonim
Publisher : Elsevier
Page : 494 pages
File Size : 43,5 Mb
Release : 1999-09-06
Category : Science
ISBN : 9780080496665

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Enzyme Kinetics and Mechanisms, Part E, Energetics of Enzyme Catalysis by Anonim Pdf

This volume supplements Volumes 63, 64, 87, and 249 of Methods in Enzymology. These volumes provide a basic source for the quantitative interpretation of enzyme rate data and the analysis of enzyme catalysis. Among the major topics covered are Engergetic Coupling in Enzymatic Reactions, Intermediates and Complexes in Catalysis, Detection and Properties of Low Barrier Hydrogen Bonds, Transition State Determination, and Inhibitors. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Author : Anonim
Publisher : Academic Press
Page : 0 pages
File Size : 45,9 Mb
Release : 1979-11-28
Category : Science
ISBN : 0121819639

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Enzyme Kinetics and Mechanism, Part A: Initial Rate and Inhibitor Methods by Anonim Pdf

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

Author : Athel Cornish-Bowden
Publisher : Elsevier
Page : 221 pages
File Size : 43,5 Mb
Release : 2014-05-20
Category : Science
ISBN : 9781483164670

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Principles of Enzyme Kinetics by Athel Cornish-Bowden Pdf

Principles of Enzyme Kinetics discusses the principles of enzyme kinetics at an intermediate level. It is primarily written for first-year research students in enzyme kinetics. The book is composed of 10 chapters. Chapter 1 provides the basic principles of enzyme kinetics with a brief discussion of dimensional analysis. Subsequent chapters cover topics on the essential characteristics of steady-state kinetics, temperature dependence, methods for deriving steady-state rate equations, and control of enzyme activity. Integrated rate equations, and introductions to the study of fast reactions and the statistical aspects of enzyme kinetics are provided as well. Chemists and biochemists will find the book invaluable.

Author : Daniel L. Purich
Publisher : Elsevier
Page : 920 pages
File Size : 44,6 Mb
Release : 2010-06-16
Category : Science
ISBN : 9780123809254

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Enzyme Kinetics: Catalysis and Control by Daniel L. Purich Pdf

Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. Historical analysis of kinetic principles including advanced enzyme science Provides both theoretical and practical measurements tools Coverage of single molecular kinetics Examination of force generation mechanisms Discussion of organic and inorganic enzyme reactions

Author : Perry A. Frey,Perry A. Frey and Adrian D. Hegeman,Adrian D. Hegeman
Publisher : Oxford University Press
Page : 852 pages
File Size : 46,6 Mb
Release : 2007-01-27
Category : Science
ISBN : 9780195122589

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Enzymatic Reaction Mechanisms by Perry A. Frey,Perry A. Frey and Adrian D. Hegeman,Adrian D. Hegeman Pdf

Much has happened in the field of mechanistic enzymology in the past 15 to 20 years, but books dealing with the mechanisms of enzymatic reactions were writtena generation ago and have not been updated. There is no single volume on enzymatic mechanismsto which medicinal chemists and biotechnologists can refer. As the modern day replacement for C.T. Walsh's classic 1979 book on the subject, Frey and Hegeman's text promises to be an instant success.

Author : Daniel L. Purich
Publisher : Elsevier
Page : 551 pages
File Size : 46,5 Mb
Release : 2002-11-04
Category : Science
ISBN : 9780080489384

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Enzyme Kinetics and Mechanism, Part F: Detection and Characterization of Enzyme Reaction Intermediates by Daniel L. Purich Pdf

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Spectroscopic Detection of Reaction Intermediates Isotopic and Kenetic Detection of Reaction Intermediates Chemical Trapping and Inhibitor Methods for Detecting Reaction Intermediates

Author : Anonim
Publisher : Academic Press
Page : 703 pages
File Size : 46,5 Mb
Release : 2009-10-24
Category : Science
ISBN : 9780123847447

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Contemporary Enzyme Kinetics and Mechanism by Anonim Pdf

Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly discovered enzymes and therapeutic agents. Contemporary Enzyme Kinetics and Mechanism, Second Edition presents key articles from Volumes 63, 64, 87, 249, 308 and 354 of Methods in Enzymology. The chapters describe the most essential and widely applied strategies. A set of exercises and problems is included to facilitate mastery of these topics. The book will aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme inhibition will also make it attractive to pharmacologists and pharmaceutical chemists interested in rational drug design.Of the seventeen chapters presented in this new edition, ten did not previously appear in the first edition. Transient kinetic approaches to enzyme mechanisms Designing initial rate enzyme assay Deriving initial velocity and isotope exchange rate equations Plotting and statistical methods for analyzing rate data Cooperativity in enzyme function Reversible enzyme inhibitors as mechanistic probes Transition-state and multisubstrate inhibitors Affinity labeling to probe enzyme structure and function Mechanism-based enzyme inactivators Isotope exchange methods for elucidating enzymatic catalysis Kinetic isotope effects in enzyme catalysis Site-directed mutagenesis in studies of enzyme catalysis

Author : Vladimir Leskovac
Publisher : Springer Science & Business Media
Page : 439 pages
File Size : 55,7 Mb
Release : 2007-05-08
Category : Science
ISBN : 9780306483905

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Comprehensive Enzyme Kinetics by Vladimir Leskovac Pdf

Welcome to your study of enzyme kinetics, the subject that underlies all enzymology, which in turn underlies all aspects of biochemistry. This text will give you an introduction to a wide range of topics that constitute the modern enzyme kinetics. This textbook is directed at graduate students in biochemistry, chemistry, and life sciences, for advanced courses in enzyme kinetics, enzymology, and enzyme chemistry. For this reason, the whole book is organized in a systematic and scholarly fashion. It is unlikely that the student will be expected to cover everything in the text, but in a later career she or he may find it an invaluable reference for topics that are needed in practice. The concepts, definitions and detailed algebra of enzyme kinetics are laid out in accurate detail. For that reason, this textbook can also serve as a handbook for enzyme kinetics for research workers in the field. The research worker will find it a useful source, which can be used for solving the daily experimental problems in the laboratory. The preparation of the manuscript for this book was under the constant surveillance of W. Wallace Cleland, Professor of Chemical Science at the University of Wisconsin in Madison, and one of the founders of modern enzyme kinetics. Without his help and advice, this bookwould not be possible. Several versions of the manuscript were constantly corrected and improved by Svetlana Professor of Biochemistry at the University of Novi Sad.

Author : Vern L Schramm (Ed)
Publisher : Unknown
Page : 768 pages
File Size : 52,8 Mb
Release : 1999
Category : Electronic
ISBN : OCLC:780382361

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Enzyme Kinetics and Mechanism by Vern L Schramm (Ed) Pdf

Author : Anonim
Publisher : Elsevier
Page : 379 pages
File Size : 55,7 Mb
Release : 2004-07-17
Category : Science
ISBN : 9780080522616

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Liposomes, Part D by Anonim Pdf

Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. Liposomes Part D is a continuation of previous Methods in Enzymology Liposome volumes A, B, and C. Covers antibody or ligand targeted liposomes; environment sensitive liposomes; liposomal oligonucleotides; liposomes in vivo

Author : Anonim
Publisher : Elsevier
Page : 527 pages
File Size : 53,6 Mb
Release : 2004-05-25
Category : Computers
ISBN : 9780080497211

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Numerical Computer Methods, Part D by Anonim Pdf

The aim of Numerical Computer Methods, Part D is to brief researchers of the importance of data analysis in enzymology, and of the modern methods that have developed concomitantly with computer hardware. It is also to validate researchers' computer programs with real and synthetic data to ascertain that the results produced are what they expected. Selected Contents: Prediction of protein structure Modeling and studying proteins with molecular dynamics Statistical error in isothermal titration calorimetry Analysis of circular dichroism data Model comparison methods