Enzymes Of Glutamine Metabolism

Author : Jaime Mora
Publisher : Elsevier
Page : 355 pages
File Size : 49,9 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323154543

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Glutamine: Metabolism, Enzymology, and Regulation by Jaime Mora Pdf

Glutamine: Metabolism, Enzymology, and Regulation presents significant contributions on the metabolism, enzymology, and regulation of glutamine of microorganisms to higher animals. The book is a collection of papers presented during the scientific symposium of the fiftieth anniversary of the granting of the autonomy of the University of Mexico, held in Hacienda Galindo, Queretaro, Mexico in November 1979. The monograph covers glutamine metabolism centered mainly in enzymatic studies on glutamine synthetase and the enzymes that utilize glutamine; the model of cascade control of glutamine synthetase in Escherichia coli; the mechanisms that control gene expression of glutamine synthetase and its relation to nitrogen metabolism in prokaryotes; the relationship between the structure and function of glutamine synthetase in eukaryotic microorganisms; nitrogen and glutamine metabolism in plants; the role of glutamine in the animal body; and the synthesis of glutamine in animal tissues. Biologists, botanists, and zoologists will find the compendium very insightful.

Author : American Chemical Society
Publisher : Unknown
Page : 648 pages
File Size : 54,6 Mb
Release : 1973
Category : Science
ISBN : UCAL:B4493424

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The Enzymes of Glutamine Metabolism by American Chemical Society Pdf

Author : Anne Le
Publisher : Springer
Page : 186 pages
File Size : 41,7 Mb
Release : 2018-06-26
Category : Medical
ISBN : 9783319777368

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The Heterogeneity of Cancer Metabolism by Anne Le Pdf

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Author : S. Prusiner,E.R. Stadtman,American Chemical Society
Publisher : Unknown
Page : 128 pages
File Size : 53,6 Mb
Release : 1973
Category : Electronic
ISBN : OCLC:841193033

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Enzymes of Glutamine Metabolism by S. Prusiner,E.R. Stadtman,American Chemical Society Pdf

Author : D. Häussinger,H. Sies
Publisher : Springer Science & Business Media
Page : 301 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642697548

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Glutamine Metabolism in Mammalian Tissues by D. Häussinger,H. Sies Pdf

Author : Dominique Meynial-Denis
Publisher : CRC Press
Page : 848 pages
File Size : 43,6 Mb
Release : 2017-03-03
Category : Medical
ISBN : 9781315355832

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Glutamine by Dominique Meynial-Denis Pdf

Glutamine: Biochemistry, Physiology, and Clinical Applications describes the different functions of glutamine (Gln) in animals and humans. Gln is both a nutrient and a signaling molecule, and its functions go beyond those of a simple metabolic fuel or protein precursor. This book has gathered together, in an unbiased and critical manner, all the available evidence and research on Gln including pathology (neurological diseases, intestinal diseases, critical illness, and cancer), physiology (successful aging), catabolic states, immunity, and exercise. Special attention is given to the potential benefit of Gln in states of insulin resistance and the role of Gln as a "conditionally essential" amino acid. The contributors are either pioneers or experts in the area of Gln from all around the globe, including Australia, Brazil, Canada, Europe, China, and the United States. This book is a valuable source of information for nutrition scientists, medical doctors, sports scientists, food scientists, dietitians, and anyone interested in nutrition. It is also a valuable resource for students in these fields and will be an important addition to university libraries.

Author : Thorsten Cramer,Clemens A. Schmitt
Publisher : Springer
Page : 272 pages
File Size : 43,9 Mb
Release : 2016-08-24
Category : Medical
ISBN : 9783319421186

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Metabolism in Cancer by Thorsten Cramer,Clemens A. Schmitt Pdf

This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

Author : Rajkumar Rajendram,Victor R. Preedy,Vinood B. Patel
Publisher : Springer
Page : 562 pages
File Size : 47,9 Mb
Release : 2014-12-16
Category : Medical
ISBN : 9781493919321

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Glutamine in Clinical Nutrition by Rajkumar Rajendram,Victor R. Preedy,Vinood B. Patel Pdf

Glutamine is the most abundant amino acid and is a major contributor to whole body nitrogen metabolism and is considered to be “conditionally essential.” Glutamine in Health and Disease presents the application of current nutritional knowledge by physicians and dietitians and incorporates emerging fields of science and important discoveries. Section 1 covers glutamine structure and function, glutamine synthetase, glutamine binding protein, glutamine transport, glutamine-rich activation domains and transcription, glutamine transaminase and cell biochemistry. Section 2 covers glucose-independent glutamine metabolism, intestinal barrier function, thyroid-stimulating hormone, glutamine resonances, focal ischemia, plasma glutamine, metabolic stress, cancer and absorption. Section 3 covers dipeptide-bound glutamine, DNA protection, oxidative stress, NF-KB, the inflammatory response, the lung, kidney, GI tract and liver, autophagy, ethanol and diabetes. Finally, Section 4 covers the use of glutamine in preoperative states, enteral and parenteral nutrition, pulmonary infections, cancer, hypoxic injury, arginyl-glutamine, paediatrics, pancreatic surgery, the elderly, gastric emptying gastric bypass and use glutamine cocktails. Written by authors of international and national standing, leaders in the field and trendsetters, Glutamine in Health and Disease is essential reading for nutritionists and dietitians, public health scientists, physicians, epidemiologists, policy makers, and health care professionals of various disciplines.

Author : Gesellschaft Deutscher Naturforscher und Arzte,Ernst Helmreich,Helmut Holzer,Otto Wieland,2nd Int.Symp.on Interconversion of Enzymes 1971
Publisher : Springer-Verlag
Page : 444 pages
File Size : 46,5 Mb
Release : 2013-12-17
Category : Science
ISBN : 9783662379660

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Metabolic Interconversion of Enzymes by Gesellschaft Deutscher Naturforscher und Arzte,Ernst Helmreich,Helmut Holzer,Otto Wieland,2nd Int.Symp.on Interconversion of Enzymes 1971 Pdf

Author : Emily J. Erbelding
Publisher : Unknown
Page : 210 pages
File Size : 43,8 Mb
Release : 1985
Category : Diabetes
ISBN : CORNELL:31924003381468

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Glutamine Metabolism in the Small Intestine by Emily J. Erbelding Pdf

Author : Arne Schousboe,Ursula Sonnewald
Publisher : Springer
Page : 416 pages
File Size : 55,5 Mb
Release : 2016-11-25
Category : Medical
ISBN : 9783319450964

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The Glutamate/GABA-Glutamine Cycle by Arne Schousboe,Ursula Sonnewald Pdf

Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book. A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.

Author : Nenad Blau,Marinus Duran,K. Michael Gibson
Publisher : Springer Science & Business Media
Page : 860 pages
File Size : 45,9 Mb
Release : 2008-05-31
Category : Medical
ISBN : 9783540766988

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Laboratory Guide to the Methods in Biochemical Genetics by Nenad Blau,Marinus Duran,K. Michael Gibson Pdf

This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.

Author : John W. Pelley, PhD
Publisher : Elsevier Health Sciences
Page : 254 pages
File Size : 43,8 Mb
Release : 2011-11-30
Category : Medical
ISBN : 9780323074469

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Elsevier's Integrated Review Biochemistry by John W. Pelley, PhD Pdf

Effectively merge basic science and clinical skills with Elsevier's Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com - included with your purchase - allows you to conveniently access the book's complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with both case-based, andUSMLE-style questions that provide effective chapter review and quick practice for your exams. Access the full contents online at www.studentconsult.com where you'll find the complete text and illustrations, "Integration Links" to bonus content in other Student Consult titles, an interactive community center with a wealth of additional resources, and much more! Grasp and retain vital concepts more easily thanks to a color-coded format, succinct,text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material. Great for visual learners!

Author : Institute of Medicine,Committee on Military Nutrition Research
Publisher : National Academies Press
Page : 722 pages
File Size : 52,7 Mb
Release : 1999-05-13
Category : Medical
ISBN : 9780309173186

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Military Strategies for Sustainment of Nutrition and Immune Function in the Field by Institute of Medicine,Committee on Military Nutrition Research Pdf

Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.

Author : Milton H. Saier
Publisher : HarperCollins Publishers
Page : 260 pages
File Size : 41,8 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015041081665

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Enzymes in Metabolic Pathways by Milton H. Saier Pdf