Essential Current Concepts In Stem Cell Biology

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Essential Current Concepts in Stem Cell Biology

Author : Beate Brand-Saberi
Publisher : Springer Nature
Page : 247 pages
File Size : 41,5 Mb
Release : 2020-01-03
Category : Medical
ISBN : 9783030339234

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Essential Current Concepts in Stem Cell Biology by Beate Brand-Saberi Pdf

This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Concepts and Applications of Stem Cell Biology

Author : Gabriela Rodrigues,Bernard A. J. Roelen
Publisher : Springer Nature
Page : 267 pages
File Size : 44,6 Mb
Release : 2020-06-30
Category : Medical
ISBN : 9783030439392

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Concepts and Applications of Stem Cell Biology by Gabriela Rodrigues,Bernard A. J. Roelen Pdf

This textbook will support graduate students with learning materials rich in the basic concepts of stem cell biology, in its most widespread and updated perspective. The chapters are conceived in a way for students to understand the meaning of pluripotency, the definition of embryonic stem cells and the formation of multicellular structures such as organoids together with the underlying principles of their epigenetic. This textbook also discusses adult stem cells and the potential use of these cells, in particular neural, mesenchymal, and several types of muscular cells, in biomedical research and clinical applications. This textbook represents a vital complement to the text on Essential Current Concepts of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Advances in Stem Cell Research

Author : Hossein Baharvand,Nasser Aghdami
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 55,8 Mb
Release : 2012-05-26
Category : Science
ISBN : 9781617799402

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Advances in Stem Cell Research by Hossein Baharvand,Nasser Aghdami Pdf

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Stem Cells Heterogeneity - Novel Concepts

Author : Alexander Birbrair
Publisher : Springer
Page : 225 pages
File Size : 50,8 Mb
Release : 2019-04-23
Category : Science
ISBN : 9783030110963

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Stem Cells Heterogeneity - Novel Concepts by Alexander Birbrair Pdf

This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity in Different Organs, and Stem Cells Heterogeneity in Cancer, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.

Essentials of Stem Cell Biology

Author : Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut
Publisher : Academic Press
Page : 681 pages
File Size : 52,6 Mb
Release : 2009-06-05
Category : Science
ISBN : 9780080884974

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Essentials of Stem Cell Biology by Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut Pdf

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

Stem Cell Biology Basic Concepts to Frontiers Students Edition

Author : Dinender K. Singla,Paolo Di Nardo
Publisher : Createspace Independent Pub
Page : 374 pages
File Size : 55,7 Mb
Release : 2012-07-01
Category : Science
ISBN : 1466291079

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Stem Cell Biology Basic Concepts to Frontiers Students Edition by Dinender K. Singla,Paolo Di Nardo Pdf

Stem cell biology student's edition is published for the audience to learn basic knowledge on stem cells including embryonic, adult and induced pluripotent stem cells. More specifically this book describes embryonic stem cell biology, isolation and maintenance of mouse embryonic and adult stem cells, molecular mechanisms of stem cell self-renewal, nuclear cloning, genetic manipulation of stem cells, and their applications and challenges in regenerative medicine. The contents of this book are written in a simplified language for better understanding on stem cell biology for graduate and undergraduate students.

Recent Advances in Stem Cells

Author : Essam M. Abdelalim
Publisher : Springer
Page : 269 pages
File Size : 47,6 Mb
Release : 2016-09-14
Category : Medical
ISBN : 9783319332703

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Recent Advances in Stem Cells by Essam M. Abdelalim Pdf

This volume explores recent advances in the use of pluripotent stem cells (PSCs) and adult stem cells (ASCs) in basic and clinical applications. The chapters discuss use of PSCs for drug screening, genome editing, modeling of kidney, motor neuron diseases, and diabetes as well as their application in cancer; ASCs are discussed in the contexts of banking of umbilical cord stem cells, use of multipotential stromal cells (MSCs) for bone repair, cellular interactions during fracture repair stages, and therapeutic applications of neural crest stem cells and lung stem cells. The text is organized by sections dealing with PSCs and ASCs specifically, presenting the reader with a comprehensive examination of both these forms of stem cells. Expertly authored and drawing from a wealth of international perspectives, Recent Advances in Stem Cells: From Basic Research to Clinical Applications presents a succinct yet detailed review of cutting-edge research in this rapidly expanding field. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is essential reading for academics, researchers, and clinicians in the fields of cell biology, genetics, nephrology, osteology, oncology, and pulmonology.

Trends in Stem Cell Biology and Technology

Author : Hossein Baharvand
Publisher : Springer Science & Business Media
Page : 425 pages
File Size : 49,7 Mb
Release : 2009-04-20
Category : Science
ISBN : 9781603279055

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Trends in Stem Cell Biology and Technology by Hossein Baharvand Pdf

Stem cells, characterized by the ability to both self-renew and to generate diff- entiated functional cell types, have been derived from the embryo and from va- ous sources of the postnatal animals and human. The recent advances in stem cell research have led to a better understanding of self-renewal, maintenance, and diff- entiation of both embryonic and somatic stem cells. This has significantly increased our knowledge of cellular and developmental biology in general and will certainly continue to do so for a long time to come. Moreover, given their role in maintaining and replenishing tissues, stem cells represent a potential means of restoring tissue function and thereby treating the root cause of degenerative disease. Therefore, in parallel, we need to improve our cognizance of the challenges involved in applying stem cells in clinical settings. The current chapters highlight both of these aspects: that of understanding the “actual” and that of developing the “possible. ” In recognition of the growing excitement and potential of stem cells as models for both the advancement of basic science and future clinical applications, I felt it timely to edit this book in which forefront investigators would provide new findings for the use of stem cells to study various lineages and tissue types and some app- cations.

Cell Biology and Translational Medicine, Volume 6

Author : Kursad Turksen
Publisher : Springer Nature
Page : 228 pages
File Size : 53,8 Mb
Release : 2020-01-09
Category : Science
ISBN : 9783030328238

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Cell Biology and Translational Medicine, Volume 6 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the sixth volume of a continuing series.

Hematopoietic Stem Cell Biology

Author : Motonari Kondo
Publisher : Springer Science & Business Media
Page : 252 pages
File Size : 43,9 Mb
Release : 2009-12-04
Category : Medical
ISBN : 9781603273473

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Hematopoietic Stem Cell Biology by Motonari Kondo Pdf

In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. These discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs. Stem cell biology draws enormous attention not only from scientists, but also from ordinary people because of the tremendous potential for development of new therapeutic application to diseases that currently lack any type of effective therapy. Thus, this type of “regenerative medicine” is a relatively new and attractive field in both basic science and clinical medicine.

Stem Cells

Author : Mary Clarke,Jonathan Frampton
Publisher : Garland Science
Page : 966 pages
File Size : 41,9 Mb
Release : 2020-07-27
Category : Science
ISBN : 9781000062656

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Stem Cells by Mary Clarke,Jonathan Frampton Pdf

Stem cell science, encompassing basic biology to practical application, is both vast and diverse. A full appreciation of it requires an understanding of cell and molecular biology, tissue structure and physiology, the practicalities of tissue engineering and bioprocessing, and the pathways to clinical implementation—including the ethical and regulatory imperatives that our society requires us to address. Expectation and debate have been driven by the allure of regenerative medicine using stem cells as a source of replacements for damaged or aged tissues. The potential of stem cell application goes far beyond this. Highly innovative uses of stem cells are emerging as possible therapies for cancers, treating acute damage in conditions such as stroke and myocardial infarction, and resolving a whole range of diseases. Stem Cells: Biology and Application presents the basic concepts underlying the fast-moving science of stem cell biology. This textbook is written for an advanced stem cell biology course. The target audience includes senior undergraduates, first year graduate students, and practitioners in molecular biology, biology, and biomedical engineering. Stem Cells provides a comprehensive understanding of these unique cells, highlighting key areas of research, associated controversies, case studies, technologies, and pioneers in the field.

Advances in Stem Cell Research

Author : Hossein Baharvand,Nasser Aghdami
Publisher : Humana Press
Page : 398 pages
File Size : 43,9 Mb
Release : 2014-06-11
Category : Science
ISBN : 1627039589

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Advances in Stem Cell Research by Hossein Baharvand,Nasser Aghdami Pdf

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Essentials of Pluripotent Stem Cell Biology

Author : Lavonda Woods
Publisher : Hayle Medical
Page : 0 pages
File Size : 55,7 Mb
Release : 2023-09-26
Category : Medical
ISBN : 1646475933

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Essentials of Pluripotent Stem Cell Biology by Lavonda Woods Pdf

Stem cells exist in different forms depending on their origin and purpose. They require a unique environment in order to survive, sustain and develop. Stem cells are divided into four categories, namely, embryonic stem cells (ESC), adult stem cells (ASC), induced pluripotent stem cells (iPSC), and pathological stem cells (PSC). ESC and iPSC are two examples of true pluripotent stem cells. They have the ability for limitless self-renewal and can differentiate into all the specialized cell types of the body. These cells have a lot of potential applications in regenerative medicine and tissue engineering. Pluripotent stem cells hold the potential to transform treatment options for a wide variety of diseases and conditions. This book is a compilation of chapters that discuss the most vital concepts related to the biology of pluripotent stem cells. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in this area of research. For all readers who are interested in stem cell biology, the studies included in this book will serve as an excellent guide to develop a comprehensive understanding.

Dental Stem Cells

Author : Fikrettin Şahin,Ayşegül Doğan,Selami Demirci
Publisher : Springer
Page : 317 pages
File Size : 46,6 Mb
Release : 2016-06-08
Category : Science
ISBN : 9783319289472

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Dental Stem Cells by Fikrettin Şahin,Ayşegül Doğan,Selami Demirci Pdf

This book explores Dental Stem Cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells. Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer’s Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.

Stem Cell Research and Therapeutics

Author : Yanhong Shi,Dennis Clegg
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 53,5 Mb
Release : 2008-07-15
Category : Medical
ISBN : 9781402085024

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Stem Cell Research and Therapeutics by Yanhong Shi,Dennis Clegg Pdf

This book is an updated reference for one of the most exciting field of biomedical researches- Stem Cell Research and its therapeutic applications. Stem cell research holds great promise for the treatment of many human diseases that currently lack effective therapies. The set of chapters in this book provide insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and li ver degeneration. It also covers novel technologies for the culture and differentiation of both human embryonic stem cells and adult tissue stem cells. This book summarizes our current state of knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine in an overall context. It is an essential reference for students, postdoctoral fellows, academic and industrial scientists, and clinicians. v Acknowledgements The editors would like to thank Ms. Jill Brantley, Rose Chavarin, Alina Haas, and Emily Sun for their administrative assistance and proof-reading of this book. We would also like to thank all the authors for their contributions. vii The editors wish to dedicate this book to our mentors Ron Evans, Fred Gage, and, in memory of Daniel E. Koshland, Jr. Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi 1 Retinal Pigment Epithelial Cells: Development In Vivo and Derivation from Human Embryonic Stem Cells In Vitro for Treatment of Age-Related Macular Degeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Dennis O. Clegg, David Buchholz, Sherry Hikita, Teisha Rowland, Qirui Hu, and Lincoln V.