Dental Stem Cells

Author : Barbara Zavan,Eriberto Bressan
Publisher : Humana Press
Page : 288 pages
File Size : 49,8 Mb
Release : 2016-07-25
Category : Science
ISBN : 9783319332994

Get Book

Dental Stem Cells: Regenerative Potential by Barbara Zavan,Eriberto Bressan Pdf

This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology.

Author : Fikrettin Şahin,Ayşegül Doğan,Selami Demirci
Publisher : Springer
Page : 317 pages
File Size : 49,7 Mb
Release : 2016-06-08
Category : Science
ISBN : 9783319289472

Get Book

Dental Stem Cells by Fikrettin Şahin,Ayşegül Doğan,Selami Demirci Pdf

This book explores Dental Stem Cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells. Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer’s Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.

Author : Ajaykumar Vishwakarma,Paul Sharpe,Songtao Shi,Murugan Ramalingam
Publisher : Academic Press
Page : 933 pages
File Size : 43,9 Mb
Release : 2014-11-05
Category : Technology & Engineering
ISBN : 9780123977786

Get Book

Stem Cell Biology and Tissue Engineering in Dental Sciences by Ajaykumar Vishwakarma,Paul Sharpe,Songtao Shi,Murugan Ramalingam Pdf

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color

Author : Sibel Yildirim
Publisher : Springer Science & Business Media
Page : 89 pages
File Size : 52,5 Mb
Release : 2012-10-15
Category : Science
ISBN : 9781461456865

Get Book

Dental Pulp Stem Cells by Sibel Yildirim Pdf

Stem cell technology is moving forward at a tremendous rate. Recent discoveries have surprised even the most expert researchers. While every piece of new data broadens the current knowledge and contributes to this moving forward, the new data also serve as paradigm shifters of fundamental knowledge of cell biology. While the question ‘What is a Stem Cell’ may now seem to basic to even discuss, there are still some discrepancies, however, between groups in terms of their functional roles. Teeth develop from the ectoderm of the first branchial arch and the ectomesenchyme of the neural crest. Deciduous teeth start to form between the sixth and eighth weeks, and permanent teeth begin to form in the twentieth weeks. Several studies have demonstrated that the pulp from both adult teeth and deciduous teeth contains dental pulp stem cells. Several factors have made them very attractive as a model system for many researchers; they are multipotent, ethically and non-controversially available in large numbers, immuno-compatible, developmentally primitive, easy to isolate and have high expansion potential in vitro. However, many controversies still exist in the field. There are several unanswered questions in the biology of dental pulp and odontoblasts. This new volume in the SpringerBriefs in Stem Cells series presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.​

Author : Alisina Karimi ,Dr. Susheel Kumar ,Dr. Vishnuja V R Nair ,Dr. Apurva Vaidya ,Dr. Nitesh Kumar
Publisher : Book Rivers
Page : 86 pages
File Size : 41,8 Mb
Release : 2022-02-02
Category : Antiques & Collectibles
ISBN : 9789355151230

Get Book

Stem Cells in Dentistry by Alisina Karimi ,Dr. Susheel Kumar ,Dr. Vishnuja V R Nair ,Dr. Apurva Vaidya ,Dr. Nitesh Kumar Pdf

Biological solutions to biological problems are emerging as a new paradigm in dentistry and medicine. Diagnosis, treatment, therapeutics and biomaterials are all becoming biological and gene-based. We are on the verge of shifting or evolving from mechanical (e.g. surgical) to biological solutions for health promotion, risk assessment, diagnostics, treatments, therapeutics, and health care outcomes.(

Author : Sepanta Hosseinpour,Laurence J. Walsh,Keyvan Moharamzadeh
Publisher : Springer Nature
Page : 276 pages
File Size : 45,8 Mb
Release : 2021-01-25
Category : Medical
ISBN : 9783030598099

Get Book

Regenerative Approaches in Dentistry by Sepanta Hosseinpour,Laurence J. Walsh,Keyvan Moharamzadeh Pdf

This book provides evidence-based information in the field of regenerative dentistry discussing the most recent advances, current clinical applications, limitations and future directions. The coverage encompasses the regeneration of alveolar bone, the dentine-pulp complex, enamel, the periodontium and other tissues associated with the oral cavity. A full description is provided of regenerative approaches in dentistry including regenerative endodontics and tooth repair, regenerative periodontics, regenerative assisted orthodontics, regenerative approaches in oral medicine, and dental tissue derived stem cells and their potential applications. The book is written by an international team of leading experts. It will be beneficial for students, practitioners and researchers in the fields of endodontics, periodontics and implantology.

Author : Patrick Kimuyu
Publisher : GRIN Verlag
Page : 20 pages
File Size : 45,9 Mb
Release : 2018-02-07
Category : Medical
ISBN : 9783668631489

Get Book

Mesenchymal Stem Cells as New Candidates for Stemcell Based Dental Therapies by Patrick Kimuyu Pdf

Project Report from the year 2018 in the subject Medicine - Medical Frontiers and Special Areas, grade: 1, Egerton University, language: English, abstract: This paper will provide a comprehensive review on the origin and types of MSCs in the dental tissue and the oral cavity. It will also discuss their therapeutic mechanisms that make them useful in dentistry and dental treatments. Over the past few decades, stem cell research has gained extensive scientific inquiry. This aspect is attributable to the significance of stem cells in tissue engineering. It is apparent that tissue regeneration has emerged as a reliable medical approach for the treatment of tissue disorders and injuries. Initially, embryonic stem cells were preferred as candidates for regenerative medicine because these cells can be induced to replicate in a pluripotent state. However, stem cell research involving embryonic stem cells has attracted immense controversy. It is also associated with legal and ethical issues, thus limiting the use of embryonic stem cells in regenerative medicine. Fortunately, the discovery of mesenchymal stem cells (MSCs), also referred to as adult stem cells, has restored promise for the development of stem cell therapies. Unlike embryonic stem cells, MSCs are free from legal and ethical concerns. MSCs are usually pluripotent progenitor cells that are generated in an array of tissues in both foetal and adult life. It is reported that these progenitor cells differentiate into cell types of the tissues that generate them, although studies indicate that they can differentiate cell types of other tissues. Currently, MSCs are used for regenerative therapies for a number of tissue disorders and injuries including bone regeneration. For instance, MSCs generated by the dental pulps and the oral cavity tissues have been found to possess the potential for dental tissue regeneration. These cells have also been found to useful in non-dental tissue repair.

Author : Mikihito Kajiya,Anne George,Takehito Ouchi,Giovanna Orsini
Publisher : Frontiers Media SA
Page : 178 pages
File Size : 50,8 Mb
Release : 2022-02-22
Category : Science
ISBN : 9782889744763

Get Book

Stem Cells in Oral Cavity: From Development to Regeneration by Mikihito Kajiya,Anne George,Takehito Ouchi,Giovanna Orsini Pdf

Author : Dr. Shandar Siddiqui,Dr. Imran Saba
Publisher : EduBubs Publishing House
Page : 179 pages
File Size : 43,6 Mb
Release : 2020-10-14
Category : Science
ISBN : 9788194292678

Get Book

Stem Cells by Dr. Shandar Siddiqui,Dr. Imran Saba Pdf

The Indian institution of dentures sitting in a glass of water beside the bed could berendered obsolete by scientists who are confident that people will soon be able to replace lost teeth by growing new ones instead of false teeth, a small ball of cells capable of growing into a new tooth will be implanted where the missing one used to be the procedure needs only a local anesthetic and the new tooth should be fully formed within a few months of the cells being implanted. Paul Sharpe, a specialist in the field of regenerative dentistry at the Dental Institute of king's College, London, says the new procedure has distinct advantages over false teeth that require a metal post to be driven into the jaw before being capped with a porcelain or plastic tooth. The surgery today can be extensive and you need to have good solid bone in the jaw and that is a major problem for some people," The method could be used on far more patients because the ball of cells that grows in to a tooth also produces bone that anchors to the jaw. The choice of growing a new tooth is likely to appeal to patients. "Anyone who has lost teeth will tell you that, given the chance, they would rather have their own teeth than false ones," The average indian over 50 has lost 12 teeth from a set of 32. The procedure is fairly simple. Doctors take stem cells from the patient. These are unique in their ability to form any of the tissues that make up the body. By carefully nurturing the stem cells in a laboratory, scientists can nudge the cells down a path that will make them grow into a tooth. After a couple of weeks, the ball of cells, known as bud, is ready to be implanted. Tests reveal what type of tooth - for example, a molar: an incisor - the bud will form, Using a local anaesthetic, the tooth bud is inserted through a small incision into the gum. Within months, the cells will have matured into a fully-formed tooth, fused to the jawbone. As the tooth grows, it releases chemicals that encourage nerves and blood vessels to link up with it.

Author : Muhammad Fawwaz Abdullah,Khairani Idah Mokhtar,Thirumulu Ponnuraj Kannan
Publisher : Penerbit USM
Page : 128 pages
File Size : 44,9 Mb
Release : 2016-06-17
Category : Medical
ISBN : 9789838619318

Get Book

Dental Stem Cells Culturing for the Future (Penerbit USM) by Muhammad Fawwaz Abdullah,Khairani Idah Mokhtar,Thirumulu Ponnuraj Kannan Pdf

The importance of stem cells for various treatment purposes came to be realized after the advent of its prolific research. Stem cells are being popularly harvested from many sources such as embryo and bone marrow. However, harvesting and reaping the beneficial effects of stem cells from dental pulp is still cradling in its infancy. Indeed, there is a dearth of information on the detailed procedure of harvesting the stem cells from the dental pulp. This book is a compendium which highlights on the procedures of harvesting the stem cells from dental pulp and its characterization, with the aim to trigger the interests of the readers who are keen to venture further in this field. Keywords: Universiti Sains Malaysia, Penerbit Universiti Sains Malayia, Penerbit USM

Author : Meghanand Nayak,Manoj Upadhayay
Publisher : Unknown
Page : 168 pages
File Size : 49,5 Mb
Release : 2018-02-26
Category : Electronic
ISBN : 3668644233

Get Book

Stem Cells and Its Use in Dentistry by Meghanand Nayak,Manoj Upadhayay Pdf

Professorial Dissertation from the year 2018 in the subject Medicine - Dentistry, grade: -, Teerthanker Mahaveer University (Teerthanker Mahaveer Dental College & Research Centre), course: Dentistry, language: English, abstract: One of the fundamental properties of stem cell is that it does not have any tissue-specific structure that allows it to perform a specialized function. Unspecialized stem cells can give rise to specialized cells including heart muscle cells, blood cells, or nerve cells. This process is called differentiation. Several types of stem cell have been discovered from germ cells, the embryo, fetus, and adult. Each of these has promised to revolutionize the future of regenerative medicine through the provision of cell-replacement therapies to treat a variety of debilitating diseases. Stem cell research opens-up the new field of 'cell-based therapies' and, as such, several safety measures have also to be evaluated. Regenerative medicine is based on stem cells. The dental pulp contains the progenitor/stem cells which have the self-renewal capability, multi-lineage differentiation capacity and clonogenic efficiency. Dental stem cells can generate many types of tissues including bone, nerve, cartilage, teeth, and fat. However, the biology of these mysterious cells have yet to be understood and a lot more basic research is needed before new therapies using stem-cell-differentiated derivatives can be applied. Recently stem cells banks are present, and even some of these banks do not only freeze cord stem cells but also dental stem cells of baby teeth. Hence this review attempts to study the history, current concepts, evolution of stem cells in dentistry, dental stem cell banking in India, characterization of the stem cells in dentin regeneration and stem cell therapy in dentistry.

Author : Rachel J. Waddington,Alastair J. Sloan
Publisher : John Wiley & Sons
Page : 184 pages
File Size : 48,9 Mb
Release : 2016-11-18
Category : Medical
ISBN : 9781118741047

Get Book

Tissue Engineering and Regeneration in Dentistry by Rachel J. Waddington,Alastair J. Sloan Pdf

Tissue Engineering and Regeneration in Dentistry: Current Strategies presents a thorough update on the current advances, methods and understanding in tissue engineering in dentistry. It offers invaluable tools, case studies, and methodologies for undertaking research, including important biological and practical considerations to facilitate successful migration of research from the bench to the clinic. Offers detailed coverage of the basic underlying principles and scientific evidence, and includes protocols to highlight practical applications Written by an internationally renowned team of expert contributors A must-have read for researchers and specialist clinicians in tissue engineering, oral biology, dental materials science, periodontology and oral surgery

Author : Phuc Van Pham
Publisher : BoD – Books on Demand
Page : 302 pages
File Size : 48,8 Mb
Release : 2017-11-29
Category : Science
ISBN : 9789535136156

Get Book

Mesenchymal Stem Cells by Phuc Van Pham Pdf

Mesenchymal Stem Cells: Isolation, Characterization, and Applications thoroughly presents the isolation, characterization, and some applications of mesenchymal stem cells in the clinic. The book has two parts: "Isolation and Characterization" and "Clinical Perspectives and Applications." In Part I, the subsequent chapters introduce some techniques in isolation, characterization, and purification of mesenchymal stem cells in different tissues. In Part II, some applications of mesenchymal stem cells in the popular diseases, which include cartilage regeneration, spinal cord injury, and osteoarthritis, are discussed. This book provides a succinct yet comprehensive overview of mesenchymal stem cells for advanced students, graduate students, and researchers.

Author : Phuc Van Pham
Publisher : Springer
Page : 315 pages
File Size : 43,5 Mb
Release : 2017-01-24
Category : Science
ISBN : 9783319401447

Get Book

Bone and Cartilage Regeneration by Phuc Van Pham Pdf

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Author : Michel Goldberg
Publisher : Springer
Page : 281 pages
File Size : 40,9 Mb
Release : 2014-07-30
Category : Medical
ISBN : 9783642551604

Get Book

The Dental Pulp by Michel Goldberg Pdf

This book provides a detailed update on our knowledge of dental pulp and regenerative approaches to therapy. It is divided into three parts. The pulp components are first described, covering pulp cells, extracellular matrix, vascularization and innervation as well as pulp development and aging. The second part is devoted to pulp pathology and includes descriptions of the differences between reactionary and reparative dentin, the genetic alterations leading to dentinogenesis imperfecta and dentin dysplasia, the pulp reaction to dental materials, adverse impacts of bisphenol A and the effects of fluorosis, dioxin and other toxic agents. The final part of the book focuses on pulp repair and regeneration. It includes descriptions of various in vitro and in vivo (animal) experimental approaches, definition of the pulp stem cells with special focus on the stem cell niches, discussion of the regeneration of a living pulp and information on new strategies that induce pulp mineralization.