Estrogen Receptors In Human Breast Cancer

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Estrogen Receptors in Human Breast Cancer

Author : William L. McGuire
Publisher : Unknown
Page : 284 pages
File Size : 44,7 Mb
Release : 1975
Category : Breast
ISBN : 0720475406

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Estrogen Receptors in Human Breast Cancer by William L. McGuire Pdf

Estrogen Receptors in Human Breast Cancer

Author : William L. McGuire,Paul Peter Carbone,Erwin Paul Vollmer
Publisher : Unknown
Page : 320 pages
File Size : 51,5 Mb
Release : 1975
Category : Medical
ISBN : UOM:39015003796904

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Estrogen Receptors in Human Breast Cancer by William L. McGuire,Paul Peter Carbone,Erwin Paul Vollmer Pdf

Estrogens, Estrogen Receptor and Breast Cancer

Author : Fritz F. Parl
Publisher : IOS Press
Page : 280 pages
File Size : 54,5 Mb
Release : 2000
Category : Breast
ISBN : 096733554X

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Estrogens, Estrogen Receptor and Breast Cancer by Fritz F. Parl Pdf

Estrogens have been implicated to play a role in the development of breast cancer. The purpose of this book is to provide a comprehensive analysis of experimental, clinical and epidemiological evidence in support of the carcinogenicity of estrogens.

Hormonal Carcinogenesis V

Author : Jonathan J. Li,Sara A. Li,Suresh Mohla,Henri Rochefort,Thierry Maudelonde
Publisher : Springer Science & Business Media
Page : 658 pages
File Size : 51,8 Mb
Release : 2008-04-24
Category : Medical
ISBN : 9780387690803

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Hormonal Carcinogenesis V by Jonathan J. Li,Sara A. Li,Suresh Mohla,Henri Rochefort,Thierry Maudelonde Pdf

Information gathered from cell-free systems, cell cultures, animal models, and human studies, together provide important insights to our understanding of hormonal cancer causation, development, and prevention; the primary objective of these Symposia. A special emphasis is placed on the two major endocrine-related cancers, that is, breast and prostate. The emerging fields of colon, lung, and pancreatic cancers in relation to hormones are examined.

Estrogen Receptor Assays in Breast Cancer

Author : Gordon A. Sarfaty,Allan R. Nash,David D. Keightley
Publisher : Unknown
Page : 264 pages
File Size : 43,8 Mb
Release : 1981
Category : Breast
ISBN : UCAL:B4978296

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Estrogen Receptor Assays in Breast Cancer by Gordon A. Sarfaty,Allan R. Nash,David D. Keightley Pdf

Hormone Receptors in Breast Cancer

Author : Suzanne A. W. Fuqua
Publisher : Springer Science & Business Media
Page : 289 pages
File Size : 44,9 Mb
Release : 2008-12-10
Category : Medical
ISBN : 9780387094632

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Hormone Receptors in Breast Cancer by Suzanne A. W. Fuqua Pdf

Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has lead to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. This book is focused on providing this communication.

Estrogen Receptor and Breast Cancer

Author : Xiaoting Zhang
Publisher : Humana Press
Page : 432 pages
File Size : 55,6 Mb
Release : 2019-11-08
Category : Electronic
ISBN : 3030075931

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Estrogen Receptor and Breast Cancer by Xiaoting Zhang Pdf

The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

Estrogen Receptors: Advances in Research and Application: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 95 pages
File Size : 41,6 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464931819

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Estrogen Receptors: Advances in Research and Application: 2011 Edition by Anonim Pdf

Estrogen Receptors: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Estrogen Receptors in a concise format. The editors have built Estrogen Receptors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Estrogen Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Estrogen Receptors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Estrogen/antiestrogen Action and Breast Cancer Therapy

Author : Virgil Craig Jordan
Publisher : Univ of Wisconsin Press
Page : 564 pages
File Size : 49,5 Mb
Release : 1986
Category : Breast
ISBN : 029910480X

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Estrogen/antiestrogen Action and Breast Cancer Therapy by Virgil Craig Jordan Pdf

This book marks one of the achievements of the "Estrogen and Antiestrogen Action: Basic and Clinical Aspects" Wisconsin Clinical Cancer Center conference in June 1984. It is not intended to be a recount of the meeting proceedings but is, rather, a historical review of the development of this field of endeavor during the past 30 years. The chapters have been written by many of the leading experts in the field who were asked to recount the development of a particular area or laboratory idea in which they had been personally involved. The book is intended to provide both scientists and clinicians with a single-volume overview of both the basic principles of hormonal control of breast cancer and the recent clinical results from cooperative groups around the world.

Estrogen Receptor and Breast Cancer

Author : Xiaoting Zhang
Publisher : Springer
Page : 417 pages
File Size : 40,8 Mb
Release : 2018-10-16
Category : Medical
ISBN : 9783319993508

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Estrogen Receptor and Breast Cancer by Xiaoting Zhang Pdf

The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

Regulatory Mechanisms in Breast Cancer

Author : Marc E. Lippman,Robert B. Dickson
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461539407

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Regulatory Mechanisms in Breast Cancer by Marc E. Lippman,Robert B. Dickson Pdf

In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was superb, indicating a tremendous interest in basic growth regulatory mechanisms governing breast cancer and controlling its malignant progres sion. In the two years since its publication, much new and exciting in formation has been published and the full interplay of regulatory mechanisms is now beginning to emerge. We have divided this book into four sections that we hope will unify important concepts and help to crystallize areas of consensus and/or disagreement among a diverse group of basic and clinical scientists working on the disease. The first section is devoted to studies on oncogenes, antioncogenes, proliferation, and tumor prognosis. The first chapter, by Sunderland and McGuire, introduces the characteristics of breast cancer as studied by patho logists to establish prognostic outcome. Of particular interest is a new proto oncogene called HER-2 (or neu), which is rapidly becoming accepted as a valuable new tumor marker of poor prognosis. The second chapter, by Lee Bookstein and Lee, introduces the best known antioncogene, the retinoblas toma antioncogene, whose expression is sometimes lost in breast cancer. Malignant progression appears to be influenced by the balance of proto oncogene and antioncogene expression.

Current Topics

Author : William L. McGuire
Publisher : Springer
Page : 279 pages
File Size : 50,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489926630

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Current Topics by William L. McGuire Pdf

Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing better methods of diagnosis and treatment. In the pres ent volume, we tum to a series of individual topics of considerable interest, including systemic methods for hormonal ablation, screening for early cancer, male breast cancer, and more. The first chapter addresses the question of why some breast tumors metastasize and others do not. Based on elegant animal tumor models, Kim believes that metastasizing tumor cells are the undesirable by product of the host immune surveillance mechanism. Unstable mem brane structures lead to shedding of membrane constituents, abnormal locomotive properties, and evasion of the host defense system. Factors which alter membrane structure will therefore have to be considered in our approach to the management of early breast cancer.

Estrogen and Breast Cancer

Author : W. R. Miller
Publisher : Landes Bioscience
Page : 234 pages
File Size : 54,5 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015037311241

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Estrogen and Breast Cancer by W. R. Miller Pdf