Evolution Of Metabolic Pathways

Author : R. Ibrahim,L. Varin,V. De Luca,John Romeo
Publisher : Elsevier
Page : 480 pages
File Size : 53,9 Mb
Release : 2000-09-15
Category : Science
ISBN : 0080531326

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Evolution of Metabolic Pathways by R. Ibrahim,L. Varin,V. De Luca,John Romeo Pdf

The past decade has seen major advances in the cloning of genes encoding enzymes of plant secondary metabolism. This has been further enhanced by the recent project on the sequencing of the Arabidopsis genome. These developments provide the molecular genetic basis to address the question of the Evolution of Metabolic Pathways. This volume provides in-depth reviews of our current knowledge on the evolutionary origin of plant secondary metabolites and the enzymes involved in their biosynthesis. The chapters cover five major topics: 1. Role of secondary metabolites in evolution; 2. Evolutionary origins of polyketides and terpenes; 3. Roles of oxidative reactions in the evolution of secondary metabolism; 4. Evolutionary origin of substitution reactions: acylation, glycosylation and methylation; and 5. Biochemistry and molecular biology of brassinosteroids.

Author : John T. Romeo,Phytochemical Society of North America. Meeting
Publisher : Pergamon Press
Page : 467 pages
File Size : 50,7 Mb
Release : 2000
Category : Science
ISBN : 0080438601

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Evolution of Metabolic Pathways by John T. Romeo,Phytochemical Society of North America. Meeting Pdf

The past decade has seen major advances in the cloning of genes encoding enzymes of plant secondary metabolism. This has been further enhanced by the recent project on the sequencing of the Arabidopsis genome. These developments provide the molecular genetic basis to address the question of the Evolution of Metabolic Pathways. This volume provides in-depth reviews of our current knowledge on the evolutionary origin of plant secondary metabolites and the enzymes involved in their biosynthesis. The chapters cover five major topics: 1. Role of secondary metabolites in evolution; 2. Evolutionary origins of polyketides and terpenes; 3. Roles of oxidative reactions in the evolution of secondary metabolism; 4. Evolutionary origin of substitution reactions: acylation, glycosylation and methylation; and 5. Biochemistry and molecular biology of brassinosteroids.

Author : Eugene V. Koonin,Michael Galperin
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 45,5 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475737837

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Sequence — Evolution — Function by Eugene V. Koonin,Michael Galperin Pdf

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Author : Robert P. Mortlock
Publisher : CRC Press
Page : 354 pages
File Size : 46,9 Mb
Release : 1992-05-20
Category : Medical
ISBN : 0849388635

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The Evolution of Metabolic Function by Robert P. Mortlock Pdf

The Evolution of Metabolic Function presents comprehensive discussions on a variety of topics that will interest scientists and students studying the evolution of enzyme activities, the evolution of enzymatic pathways, and the evolution and development of metabolic functions. Laboratory experiments designed to develop new enzyme activities and new metabolic pathways are discussed. The most recent techniques comparing protein and gene structures are used to analyze and discuss the evolution and development of such metabolic functions as the bacterial phosphoenolpyruvate:sugar phosphotransferase system, the mandelate pathway of microorganisms, bacterial alcohol metabolism, and certain microbial amino acid biosynthetic pathways. The book also includes some unique speculations regarding the origin of early Archaean cells and the prebiotic evolution of complex molecules.

Author : David Greenberg
Publisher : Elsevier
Page : 512 pages
File Size : 48,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323162135

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Metabolic Pathways by David Greenberg Pdf

Metabolic Pathways, Third Edition: Volume IV: Nucleic Acids, Protein Synthesis, and Coenzymes focuses on the metabolic pathways of the major biological constituents of living organisms, namely, nucleic acids, proteins, and coenzymes. The biosynthesis and metabolism of purines and pyrimidines, nucleotides, riboflavin and related compounds, and vitamin B6 are discussed. The biogenesis and metabolism of thiamine and folic acid are also considered. This volume is comprised of seven chapters and begins with an analysis of metabolic control and enzymology of purines and pyrimidines such as inosinic acid and nucleotides. The next chapter is devoted to the biosynthesis and metabolism of nucleotides and nucleic acids, making reference to deoxyribonucleotides as well as RNA and DNA. Some of the reactions involving nucleotides are classified and briefly discussed. The reader is then introduced to protein synthesis, paying particular attention to the chemical features of the synthesis of the peptide bond and the characteristics of the genetic code implicated in this process. The remaining chapters focus on riboflavin and related compounds, thiamine, folic acid, and vitamin B6. This book will be a useful resource for biochemists and biologists.

Author : William F. Martin,Aloysius G. M. Tielens,Marek Mentel
Publisher : Walter de Gruyter GmbH & Co KG
Page : 269 pages
File Size : 41,8 Mb
Release : 2020-12-07
Category : Science
ISBN : 9783110612417

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Mitochondria and Anaerobic Energy Metabolism in Eukaryotes by William F. Martin,Aloysius G. M. Tielens,Marek Mentel Pdf

Mitochondria are sometimes called the powerhouses of eukaryotic cells, because mitochondria are the site of ATP synthesis in the cell. ATP is the universal energy currency, it provides the power that runs all other life processes. Humans need oxygen to survive because of ATP synthesis in mitochondria. The sugars from our diet are converted to carbon dioxide in mitochondria in a process that requires oxygen. Just like a fire needs oxygen to burn, our mitochondria need oxygen to make ATP. From textbooks and popular literature one can easily get the impression that all mitochondria require oxygen. But that is not the case. There are many groups of organismsm known that make ATP in mitochondria without the help of oxygen. They have preserved biochemical relicts from the early evolution of eukaryotic cells, which took place during times in Earth history when there was hardly any oxygen avaiable, certainly not enough to breathe. How the anaerobic forms of mitochondria work, in which organisms they occur, and how the eukaryotic anaerobes that possess them fit into the larger picture of rising atmospheric oxygen during Earth history are the topic of this book.

Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 41,6 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457

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Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Author : Christina Smolke
Publisher : CRC Press
Page : 581 pages
File Size : 45,5 Mb
Release : 2009-07-28
Category : Science
ISBN : 142007766X

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The Metabolic Pathway Engineering Handbook by Christina Smolke Pdf

This second volume of the Metabolic Pathway Engineering Handbook delves into evolutionary tools and gene expression tools for metabolic pathway engineering. It covers applications of emerging technologies including recent research genome-wide technologies, DNA and phenotypic microarrays, and proteomics tools for experimentally determining flux through pathways. This volume also looks at emerging applications for producing fine chemicals, drugs, and alternative fuels. Christine Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the most brilliant new minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting edge research and analysis, this work also serves as an invaluable resource for those seeking to add their own contributions. Organized by topic, this 3000 page reference is available as two volumes that can be purchased individually or as a set.

Author : Julianne Zedalis,John Eggebrecht
Publisher : Unknown
Page : 1923 pages
File Size : 44,9 Mb
Release : 2017-10-16
Category : Biology
ISBN : 1947172409

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Biology for AP ® Courses by Julianne Zedalis,John Eggebrecht Pdf

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 570 pages
File Size : 41,6 Mb
Release : 2011-12-30
Category : Science
ISBN : 9780309219396

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The Science and Applications of Synthetic and Systems Biology by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 49,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Milton H. Saier
Publisher : HarperCollins Publishers
Page : 260 pages
File Size : 52,9 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015041081665

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Enzymes in Metabolic Pathways by Milton H. Saier Pdf

Author : Jonathan C. K. Wells
Publisher : Cambridge University Press
Page : 625 pages
File Size : 43,7 Mb
Release : 2016-07-21
Category : Business & Economics
ISBN : 9781107009479

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The Metabolic Ghetto by Jonathan C. K. Wells Pdf

A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.

Author : Michael Schwarzer,Torsten Doenst
Publisher : Academic Press
Page : 240 pages
File Size : 46,8 Mb
Release : 2015-11-04
Category : Medical
ISBN : 9780128026144

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The Scientist's Guide to Cardiac Metabolism by Michael Schwarzer,Torsten Doenst Pdf

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

Author : William E. G. Thomas,William Ernest Ghinn Thomas,Malcolm W. R. Reed,Michael G. Wyatt
Publisher : Oxford University Press
Page : 849 pages
File Size : 50,9 Mb
Release : 2016-07-28
Category : Medical
ISBN : 9780199665549

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Oxford Textbook of Fundamentals of Surgery by William E. G. Thomas,William Ernest Ghinn Thomas,Malcolm W. R. Reed,Michael G. Wyatt Pdf

A definitive, accessible, and reliable resource which provides a solid foundation of the knowledge and basic science needed to hone all of the core surgical skills used in surgical settings. Presented in a clear and accessible way it addresses the cross-specialty aspects of surgery applicable to all trainees.