Evolutionary Quantitative Genetics

Author : Derek A. Roff
Publisher : Springer Science & Business Media
Page : 503 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461540809

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Evolutionary Quantitative Genetics by Derek A. Roff Pdf

The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti tative genetic theory. However, as the book was concerned with the evolution of life histories and traits connected to this, the presence of quantitative genetic variation was an underlying theme throughout. Much of the focus was placed on optimality theory, for it is this approach that has proven to be extremely successful in the analysis of life history variation. But quantitative genetics cannot be ig nored, because there are some questions for which optimality approaches are inappropriate; for example, although optimality modeling can address the ques tion of the maintenance of phenotypic variation, it cannot say anything about genetic variation, on which further evolution clearly depends. The present book is, thus, a natural extension of the first. I have approached the problem not from the point of view of an animal or plant breeder but from that of one interested in understanding the evolution of quantitative traits in wild populations. The subject is large with a considerable body of theory: I generally present the assumptions underlying the analysis and the results, giving the relevant references for those interested in the intervening mathematics. My interest is in what quantitative genetics tells me about evolutionary processes; therefore, I have concentrated on areas of research most relevant to field studies.

Author : Stevan J. Arnold
Publisher : Oxford University Press
Page : 497 pages
File Size : 53,5 Mb
Release : 2023-06-06
Category : Science
ISBN : 9780192675538

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Evolutionary Quantitative Genetics by Stevan J. Arnold Pdf

Evolutionary quantitative genetics (EQG) provides a formal theoretical foundation for quantitatively linking natural selection and genetic variation to the rate and expanse of adaptive evolution. It has become the dominant conceptual framework for interpreting the evolution of quantitative traits in terms of elementary forces (mutation, inheritance, selection, and drift). Despite this success, the relevance of EQG to many biological scenarios remains relatively unappreciated, with numerous fields yet to fully embrace its approach. Part of the reason for this lag is that conceptual advances in EQG have not yet been fully synthesized and made accessible to a wider academic audience. A comprehensive, accessible overview is therefore now timely, and Evolutionary Quantitative Genetics provides this much-needed synthesis. The central argument of the book is that an adaptive landscape concept can be used to understand both evolutionary process within lineages and the pattern of adaptive radiations. In particular, it provides a convincing argument that models with a moving adaptive peak carry us further than any other conceptual approach yet devised. Although additive theory holds center stage, the book mentions and references departures from additivity including non-Gaussian distributions of allelic effects, dominance, epistasis, maternal effects and phenotypic plasticity. This accessible, advanced textbook is aimed principally at students (from senior undergraduate to postgraduate) as well as practising scientists in the fields of evolutionary biology, ecology, physiology, functional morphology, developmental biology, comparative biology, paleontology, and beyond who are interested in how adaptive radiations are produced by evolutionary and ecological processes.

Author : David J. Balding,Ida Moltke,John Marioni
Publisher : John Wiley & Sons
Page : 1828 pages
File Size : 45,9 Mb
Release : 2019-07-09
Category : Science
ISBN : 9781119429258

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Handbook of Statistical Genomics by David J. Balding,Ida Moltke,John Marioni Pdf

A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Author : Derek A Roff
Publisher : Unknown
Page : 512 pages
File Size : 52,6 Mb
Release : 1997-07-31
Category : Electronic
ISBN : 146154081X

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Evolutionary Quantitative Genetics by Derek A Roff Pdf

Author : Christine R. B. Boake
Publisher : University of Chicago Press
Page : 400 pages
File Size : 51,7 Mb
Release : 1994-08-15
Category : Science
ISBN : 9780226062167

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Quantitative Genetic Studies of Behavioral Evolution by Christine R. B. Boake Pdf

Taken together, these studies document both the benefits and pitfalls of quantitative genetics.

Author : Bruce Walsh,Michael Lynch
Publisher : Oxford University Press
Page : 1504 pages
File Size : 48,6 Mb
Release : 2018-06-21
Category : Science
ISBN : 9780192566645

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Evolution and Selection of Quantitative Traits by Bruce Walsh,Michael Lynch Pdf

Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

Author : Armando Caballero
Publisher : Cambridge University Press
Page : 343 pages
File Size : 45,6 Mb
Release : 2020-04-23
Category : Mathematics
ISBN : 9781108481410

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Quantitative Genetics by Armando Caballero Pdf

An up-to-date, accessible guide to the main concepts and applications of quantitative genetics.

Author : Anne Charmantier,Dany Garant,Loeske E. B. Kruuk
Publisher : Oxford University Press
Page : 293 pages
File Size : 54,5 Mb
Release : 2014
Category : Science
ISBN : 9780199674237

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Quantitative Genetics in the Wild by Anne Charmantier,Dany Garant,Loeske E. B. Kruuk Pdf

Across these fields, there is increasing appreciation of the need to quantify the genetic - rather than just the phenotypic - basis and diversity of key traits, the genetic basis of the associations between traits, and the interaction between these genetic effects and the environment. This research activity has been fuelled by methodological advances in both molecular genetics and statistics, as well as by exciting results emerging from laboratory studies of evolutionary quantitative genetics, and the increasing availability of suitable long-term datasets collected in natural populations, especially in animals. Quantitative Genetics in the Wild is the first book to synthesize the current level of knowledge in this exciting and rapidly-expanding area.

Author : Anne Charmantier,Dany Garant,Loeske E. B. Kruuk
Publisher : Oxford University Press, USA
Page : 293 pages
File Size : 54,7 Mb
Release : 2014
Category : Science
ISBN : 9780199674244

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Quantitative Genetics in the Wild by Anne Charmantier,Dany Garant,Loeske E. B. Kruuk Pdf

Although the field of quantitative genetics is almost 100 years old, its application to the study of evolutionary processes in wild populations has expanded greatly over the last few decades.

Author : Michael Lynch,Bruce Walsh
Publisher : Sinauer Associates Incorporated
Page : 980 pages
File Size : 42,8 Mb
Release : 1998-01
Category : Science
ISBN : 0878934812

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Genetics and Analysis of Quantitative Traits by Michael Lynch,Bruce Walsh Pdf

Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Author : Alan R. Templeton
Publisher : John Wiley & Sons
Page : 720 pages
File Size : 53,8 Mb
Release : 2006-09-29
Category : Science
ISBN : 9780470047217

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Population Genetics and Microevolutionary Theory by Alan R. Templeton Pdf

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Author : Tim R. Birkhead,Dave J. Hosken,Scott S. Pitnick
Publisher : Academic Press
Page : 674 pages
File Size : 51,5 Mb
Release : 2008-11-21
Category : Science
ISBN : 0080919871

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Sperm Biology by Tim R. Birkhead,Dave J. Hosken,Scott S. Pitnick Pdf

Sperm Biology represents the first analysis of the evolutionary significance of sperm phenotypes and derived sperm traits and the possible selection pressures responsible for sperm-egg coevolution. An understanding of sperm evolution is fast developing and promises to shed light on many topics from basic reproductive biology to the evolutionary process itself as well as the sperm proteome, the sperm genome and the quantitative genetics of sperm. The Editors have identified 15 topics of current interest and biological significance to cover all aspects of this bizarre, fascinating and important subject. It comprises the most comprehensive and up-to-date review of the evolution of sperm and pointers for future research, written by experts in both sperm biology and evolutionary biology. The combination of evolution and sperm is a potent mix, and this is the definitive account. The first review survey of this emerging field Written by experts from a broad array of disciplines from the physiological and biomedical to the ecological and evolutionary Sheds light on the intricacies of reproduction and the coevolution of sperm, egg and reproductive behavior

Author : Brian Charlesworth,Deborah Charlesworth
Publisher : Roberts
Page : 776 pages
File Size : 53,5 Mb
Release : 2010-02-03
Category : Science
ISBN : STANFORD:36105215340113

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Elements of Evolutionary Genetics by Brian Charlesworth,Deborah Charlesworth Pdf

This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.

Author : Volker Loeschcke
Publisher : Springer Science & Business Media
Page : 192 pages
File Size : 51,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642727702

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Genetic Constraints on Adaptive Evolution by Volker Loeschcke Pdf

Genetic constraints on adaptive evolution can be understood as those genetic aspects that prevent or reduce the potential for natural selection to result in the most direct ascent of the mean phenotype to an optimum. The contributions to this volume emphasize how genetic aspects in the transmission of traits constrain adaptive evolution. Approaches span from quantitative, population, ecological to molecular genetics. Much attention is devoted to genetic correlations, to the maintenance of quantitative genetic variation, and to the intimate relation between genetics, ecology, and evolution. This volume addresses all evolutionary biologists and explains why they should be wary of evolutionary concepts that base arguments purely on phenotypic characteristics.

Author : Glenn-Peter Sætre,Mark Ravinet
Publisher : Oxford University Press, USA
Page : 327 pages
File Size : 51,9 Mb
Release : 2019-05
Category : Science
ISBN : 9780198830917

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Evolutionary Genetics by Glenn-Peter Sætre,Mark Ravinet Pdf

Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. The book also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Furthermore, at the end of each chapter, study questions are provided to motivate the reader to think and reflect on the concepts introduced. Practical experience is essential when it comes to developing an understanding of how to use genetic and genomic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and the analysis of evolutionary genetic data. The R environment stands out as an ideal all-purpose, open source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.