Evolution And Selection Of Quantitative Traits

Author : Bruce Walsh,Michael Lynch
Publisher : Oxford University Press
Page : 1504 pages
File Size : 46,6 Mb
Release : 2018-06-21
Category : Science
ISBN : 9780192566645

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Evolution and Selection of Quantitative Traits by Bruce Walsh,Michael Lynch Pdf

Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

Author : Stevan J. Arnold
Publisher : Oxford University Press
Page : 497 pages
File Size : 44,6 Mb
Release : 2023-06-06
Category : Science
ISBN : 9780192675538

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Evolutionary Quantitative Genetics by Stevan J. Arnold Pdf

Evolutionary quantitative genetics (EQG) provides a formal theoretical foundation for quantitatively linking natural selection and genetic variation to the rate and expanse of adaptive evolution. It has become the dominant conceptual framework for interpreting the evolution of quantitative traits in terms of elementary forces (mutation, inheritance, selection, and drift). Despite this success, the relevance of EQG to many biological scenarios remains relatively unappreciated, with numerous fields yet to fully embrace its approach. Part of the reason for this lag is that conceptual advances in EQG have not yet been fully synthesized and made accessible to a wider academic audience. A comprehensive, accessible overview is therefore now timely, and Evolutionary Quantitative Genetics provides this much-needed synthesis. The central argument of the book is that an adaptive landscape concept can be used to understand both evolutionary process within lineages and the pattern of adaptive radiations. In particular, it provides a convincing argument that models with a moving adaptive peak carry us further than any other conceptual approach yet devised. Although additive theory holds center stage, the book mentions and references departures from additivity including non-Gaussian distributions of allelic effects, dominance, epistasis, maternal effects and phenotypic plasticity. This accessible, advanced textbook is aimed principally at students (from senior undergraduate to postgraduate) as well as practising scientists in the fields of evolutionary biology, ecology, physiology, functional morphology, developmental biology, comparative biology, paleontology, and beyond who are interested in how adaptive radiations are produced by evolutionary and ecological processes.

Author : Derek A. Roff
Publisher : Springer Science & Business Media
Page : 503 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461540809

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Evolutionary Quantitative Genetics by Derek A. Roff Pdf

The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti tative genetic theory. However, as the book was concerned with the evolution of life histories and traits connected to this, the presence of quantitative genetic variation was an underlying theme throughout. Much of the focus was placed on optimality theory, for it is this approach that has proven to be extremely successful in the analysis of life history variation. But quantitative genetics cannot be ig nored, because there are some questions for which optimality approaches are inappropriate; for example, although optimality modeling can address the ques tion of the maintenance of phenotypic variation, it cannot say anything about genetic variation, on which further evolution clearly depends. The present book is, thus, a natural extension of the first. I have approached the problem not from the point of view of an animal or plant breeder but from that of one interested in understanding the evolution of quantitative traits in wild populations. The subject is large with a considerable body of theory: I generally present the assumptions underlying the analysis and the results, giving the relevant references for those interested in the intervening mathematics. My interest is in what quantitative genetics tells me about evolutionary processes; therefore, I have concentrated on areas of research most relevant to field studies.

Author : Michael Lynch,Bruce Walsh
Publisher : Sinauer Associates Incorporated
Page : 980 pages
File Size : 46,9 Mb
Release : 1998-01
Category : Science
ISBN : 0878934812

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Genetics and Analysis of Quantitative Traits by Michael Lynch,Bruce Walsh Pdf

Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Author : David J. Balding,Ida Moltke,John Marioni
Publisher : John Wiley & Sons
Page : 1828 pages
File Size : 52,8 Mb
Release : 2019-07-09
Category : Science
ISBN : 9781119429258

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Handbook of Statistical Genomics by David J. Balding,Ida Moltke,John Marioni Pdf

A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Author : Anne Charmantier,Dany Garant,Loeske E. B. Kruuk
Publisher : Oxford University Press
Page : 293 pages
File Size : 47,9 Mb
Release : 2014
Category : Science
ISBN : 9780199674237

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Quantitative Genetics in the Wild by Anne Charmantier,Dany Garant,Loeske E. B. Kruuk Pdf

Across these fields, there is increasing appreciation of the need to quantify the genetic - rather than just the phenotypic - basis and diversity of key traits, the genetic basis of the associations between traits, and the interaction between these genetic effects and the environment. This research activity has been fuelled by methodological advances in both molecular genetics and statistics, as well as by exciting results emerging from laboratory studies of evolutionary quantitative genetics, and the increasing availability of suitable long-term datasets collected in natural populations, especially in animals. Quantitative Genetics in the Wild is the first book to synthesize the current level of knowledge in this exciting and rapidly-expanding area.

Author : Anne Charmantier,Dany Garant,Loeske E. B. Kruuk
Publisher : OUP Oxford
Page : 288 pages
File Size : 42,8 Mb
Release : 2014-04-03
Category : Science
ISBN : 9780191655951

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Quantitative Genetics in the Wild by Anne Charmantier,Dany Garant,Loeske E. B. Kruuk Pdf

Although the field of quantitative genetics - the study of the genetic basis of variation in quantitative characteristics such as body size, or reproductive success - is almost 100 years old, its application to the study of evolutionary processes in wild populations has expanded greatly over the last few decades. During this time, the use of 'wild quantitative genetics' has provided insights into a range of important questions in evolutionary ecology, ranging from studies conducting research in well-established fields such as life-history theory, behavioural ecology and sexual selection, to others addressing relatively new issues such as populations' responses to climate change or the process of senescence in natural environments. Across these fields, there is increasing appreciation of the need to quantify the genetic - rather than just the phenotypic - basis and diversity of key traits, the genetic basis of the associations between traits, and the interaction between these genetic effects and the environment. This research activity has been fuelled by methodological advances in both molecular genetics and statistics, as well as by exciting results emerging from laboratory studies of evolutionary quantitative genetics, and the increasing availability of suitable long-term datasets collected in natural populations, especially in animals. Quantitative Genetics in the Wild is the first book to synthesize the current level of knowledge in this exciting and rapidly-expanding area. This comprehensive volume also offers exciting perspectives for future studies in emerging areas, including the application of quantitative genetics to plants or arthropods, unraveling the molecular basis of variation in quantitative traits, or estimating non-additive genetic variance. Since this book deals with many fundamental questions in evolutionary ecology, it should be of interest to graduate, post-graduate students, and academics from a wide array of fields such as animal behaviour, ecology, evolution, and genetics.

Author : Christine R. B. Boake
Publisher : University of Chicago Press
Page : 400 pages
File Size : 46,6 Mb
Release : 1994-08-15
Category : Science
ISBN : 9780226062167

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Quantitative Genetic Studies of Behavioral Evolution by Christine R. B. Boake Pdf

Taken together, these studies document both the benefits and pitfalls of quantitative genetics.

Author : Douglas Scott Falconer
Publisher : Longman Publishing Group
Page : 356 pages
File Size : 47,6 Mb
Release : 1981
Category : Science
ISBN : UOM:39015012536523

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Introduction to Quantitative Genetics by Douglas Scott Falconer Pdf

The lastest edition of this classic text continues to provide the basis for understanding the genetic principles behind quantitative differences in phenotypes and how they apply to animal and plant improvement and evolution. It extends these concepts to the segregation of genes that cause genetic variation in quantitative traits. Key techniques and methods are also covered.

Author : Armando Caballero
Publisher : Cambridge University Press
Page : 343 pages
File Size : 49,6 Mb
Release : 2020-04-23
Category : Mathematics
ISBN : 9781108481410

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Quantitative Genetics by Armando Caballero Pdf

An up-to-date, accessible guide to the main concepts and applications of quantitative genetics.

Author : Derek A Roff
Publisher : Unknown
Page : 512 pages
File Size : 45,5 Mb
Release : 1997-07-31
Category : Electronic
ISBN : 146154081X

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Evolutionary Quantitative Genetics by Derek A Roff Pdf

Author : National Academy of Sciences
Publisher : Sackler Colloquium
Page : 388 pages
File Size : 45,9 Mb
Release : 2007
Category : Science
ISBN : UOM:39015073872999

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In the Light of Evolution by National Academy of Sciences Pdf

The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Author : John A. Endler
Publisher : Princeton University Press
Page : 352 pages
File Size : 53,5 Mb
Release : 2020-03-31
Category : Science
ISBN : 9780691209517

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Natural Selection in the Wild. (MPB-21), Volume 21 by John A. Endler Pdf

Natural selection is an immense and important subject, yet there have been few attempts to summarize its effects on natural populations, and fewer still which discuss the problems of working with natural selection in the wild. These are the purposes of John Endler's book. In it, he discusses the methods and problems involved in the demonstration and measurement of natural selection, presents the critical evidence for its existence, and places it in an evolutionary perspective. Professor Endler finds that there are a remarkable number of direct demonstrations of selection in a wide variety of animals and plants. The distribution of observed magnitudes of selection in natural populations is surprisingly broad, and it overlaps extensively the range of values found in artificial selection. He argues that the common assumption that selection is usually weak in natural populations is no longer tenable, but that natural selection is only one component of the process of evolution; natural selection can explain the change of frequencies of variants, but not their origins.

Author : Oliver Mayo
Publisher : Unknown
Page : 168 pages
File Size : 43,9 Mb
Release : 1983
Category : Evolution
ISBN : UCSD:31822000484790

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Natural Selection and Its Constraints by Oliver Mayo Pdf

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences
Publisher : National Academies Press
Page : 201 pages
File Size : 40,8 Mb
Release : 2020-12-18
Category : Science
ISBN : 9780309676731

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Next Steps for Functional Genomics by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences Pdf

One of the holy grails in biology is the ability to predict functional characteristics from an organism's genetic sequence. Despite decades of research since the first sequencing of an organism in 1995, scientists still do not understand exactly how the information in genes is converted into an organism's phenotype, its physical characteristics. Functional genomics attempts to make use of the vast wealth of data from "-omics" screens and projects to describe gene and protein functions and interactions. A February 2020 workshop was held to determine research needs to advance the field of functional genomics over the next 10-20 years. Speakers and participants discussed goals, strategies, and technical needs to allow functional genomics to contribute to the advancement of basic knowledge and its applications that would benefit society. This publication summarizes the presentations and discussions from the workshop.