Examining The Use Of Biomarkers In Establishing The Presence And Severity Of Impairments
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National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services Publisher : National Academies Press Page : 85 pages File Size : 55,5 Mb Release : 2021-01-15 Category : Medical ISBN : 9780309682633
Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services Pdf
As part of the overall disability determination process, the Social Security Administration uses a step-by-step approach to understand how severe an individual's condition is and whether it meets program criteria for disability. The use of various types of biomarkers has been suggested as a way to strengthen the amount and quality of objective evidence available to the review process. At the request of the Social Security Administration, the National Academies of Sciences, Engineering, and Medicine's Board on Health Care Services organized a virtual workshop on July 21, 2020, titled The State of the Science of the Use of Biomarkers to Establish the Presence and Severity of Impairments. Workshop discussions focused on the current and potential uses for biomarkers; explored legal and ethical implications associated with biomarker use in clinical decision making; and considered the possible uses of nongenetic biomarkers as tools for the diagnosis or prognosis of the severity of specific physical and mental impairments. This publication summarizes the presentations and discussion of the workshop.
Nathan D. Zasler, MD,Douglas I. Katz, MD,Ross D. Zafonte, DO
Author : Nathan D. Zasler, MD,Douglas I. Katz, MD,Ross D. Zafonte, DO Publisher : Springer Publishing Company Page : 1891 pages File Size : 40,9 Mb Release : 2021-09-01 Category : Medical ISBN : 9780826143051
Brain Injury Medicine, Third Edition by Nathan D. Zasler, MD,Douglas I. Katz, MD,Ross D. Zafonte, DO Pdf
“This updated textbook was much needed as there has been increased attention in recent years toward brain injuries. The book provides updated guidelines and clinical practice recommendations that support the intended audience of trainees and current practitioners. This update makes it the current standard text for any brain injury specialist." ---Doody's Review Service, 4 stars This revised and greatly expanded Third Edition of Brain Injury Medicine continues its reputation as the key core textbook in the field, bringing together evidence-based medicine and years of collective author clinical experience in a clear and comprehensive guide for brain injury professionals. Universally praised as the gold standard text and go-to clinical reference, the book covers the entire continuum of care from early diagnosis and assessment through acute management, rehabilitation, associated medical and quality of life issues, and functional outcomes. With 12 new chapters and expanded coverage in key areas of pathobiology and neuro-recovery, special populations, sport concussion, disorders of consciousness, neuropharmacology, and more, this "state of the science" resource promotes a multi-disciplinary approach to a complex condition with consideration of emerging topics and the latest clinical advances. Written by over 200 experts from all involved disciplines, the text runs the full gamut of practice of brain injury medicine including principles of public health and research, biomechanics and neural recovery, neuroimaging and neurodiagnostic testing, sport and military, prognosis and outcome, acute care, treatment of special populations, neurologic and other medical complications post-injury, motor and musculoskeletal problems, post-trauma pain disorders, cognitive and behavioral problems, functional mobility, neuropharmacology and alternative treatments, community reentry, and medicolegal and ethical issues. Unique in its scope of topics relevant to professionals working with patients with brain injury, this third edition offers the most complete and contemporary review of clinical practice standards in the field. Key Features: Thoroughly revised and updated Third Edition of the seminal reference on brain injury medicine Evidence-based consideration of emerging topics with new chapters covering pathobiology, biomarkers, neurorehabilitation nursing, neurodegenerative dementias, anoxic/hypoxic ischemic brain injury, infectious causes of acquired brain injury, neuropsychiatric assessment, PTSD, and capacity assessment Multi-disciplinary authorship with leading experts from a wide range of specialties including but not limited to physiatry, neurology, psychiatry, neurosurgery, neuropsychology, physical therapy, occupational therapy speech language pathology, and nursing New online chapters on survivorship, family perspectives, and resources for persons with brain injury and their caregivers Purchase includes digital access for use on most mobile devices or computers
National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Health Care Utilization and Adults with Disabilities
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Health Care Utilization and Adults with Disabilities Publisher : National Academies Press Page : 161 pages File Size : 46,6 Mb Release : 2018-04-02 Category : Medical ISBN : 9780309469210
Health-Care Utilization as a Proxy in Disability Determination by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Health Care Utilization and Adults with Disabilities Pdf
The Social Security Administration (SSA) administers two programs that provide benefits based on disability: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. This report analyzes health care utilizations as they relate to impairment severity and SSA's definition of disability. Health Care Utilization as a Proxy in Disability Determination identifies types of utilizations that might be good proxies for "listing-level" severity; that is, what represents an impairment, or combination of impairments, that are severe enough to prevent a person from doing any gainful activity, regardless of age, education, or work experience.
Institute of Medicine,Board on the Health of Select Populations,Committee on Psychological Testing, Including Validity Testing, for Social Security Administration Disability Determinations
Author : Institute of Medicine,Board on the Health of Select Populations,Committee on Psychological Testing, Including Validity Testing, for Social Security Administration Disability Determinations Publisher : National Academies Press Page : 246 pages File Size : 53,7 Mb Release : 2015-06-29 Category : Medical ISBN : 9780309370936
Psychological Testing in the Service of Disability Determination by Institute of Medicine,Board on the Health of Select Populations,Committee on Psychological Testing, Including Validity Testing, for Social Security Administration Disability Determinations Pdf
The United States Social Security Administration (SSA) administers two disability programs: Social Security Disability Insurance (SSDI), for disabled individuals, and their dependent family members, who have worked and contributed to the Social Security trust funds, and Supplemental Security Income (SSSI), which is a means-tested program based on income and financial assets for adults aged 65 years or older and disabled adults and children. Both programs require that claimants have a disability and meet specific medical criteria in order to qualify for benefits. SSA establishes the presence of a medically-determined impairment in individuals with mental disorders other than intellectual disability through the use of standard diagnostic criteria, which include symptoms and signs. These impairments are established largely on reports of signs and symptoms of impairment and functional limitation. Psychological Testing in the Service of Disability Determination considers the use of psychological tests in evaluating disability claims submitted to the SSA. This report critically reviews selected psychological tests, including symptom validity tests, that could contribute to SSA disability determinations. The report discusses the possible uses of such tests and their contribution to disability determinations. Psychological Testing in the Service of Disability Determination discusses testing norms, qualifications for administration of tests, administration of tests, and reporting results. The recommendations of this report will help SSA improve the consistency and accuracy of disability determination in certain cases.
Institute of Medicine,Food and Nutrition Board,Board on Health Sciences Policy,Board on Health Care Services,Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease
Author : Institute of Medicine,Food and Nutrition Board,Board on Health Sciences Policy,Board on Health Care Services,Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease Publisher : National Academies Press Page : 335 pages File Size : 55,8 Mb Release : 2010-06-25 Category : Medical ISBN : 9780309157278
Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease by Institute of Medicine,Food and Nutrition Board,Board on Health Sciences Policy,Board on Health Care Services,Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease Pdf
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.
Autism Spectrum Disorders by Andreas M. Grabrucker Pdf
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
Institute of Medicine,Board on the Health of Select Populations,Committee on Social Security Cardiovascular Disability Criteria
Author : Institute of Medicine,Board on the Health of Select Populations,Committee on Social Security Cardiovascular Disability Criteria Publisher : National Academies Press Page : 304 pages File Size : 55,7 Mb Release : 2010-12-04 Category : Medical ISBN : 9780309156981
Cardiovascular Disability by Institute of Medicine,Board on the Health of Select Populations,Committee on Social Security Cardiovascular Disability Criteria Pdf
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on the Review of the Department of Veterans Affairs Examinations for Traumatic Brain Injury
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on the Review of the Department of Veterans Affairs Examinations for Traumatic Brain Injury Publisher : National Academies Press Page : 211 pages File Size : 50,6 Mb Release : 2019-05-20 Category : Medical ISBN : 9780309486897
Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on the Review of the Department of Veterans Affairs Examinations for Traumatic Brain Injury Pdf
The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.
Biomarkers to predict, prevent and find the appropriate treatments of disorders in childhood by Kristin Skogstrand,Nis Borbye-Lorenzen,Ulrik Lausten-Thomsen,Marie Bækvad-Hansen Pdf
Biomarkers in Psychiatry by Judith Pratt,Jeremy Hall Pdf
This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.
Evidence-Based Practice of Critical Care E-Book by Clifford S. Deutschman,Patrick J. Neligan Pdf
Approach any critical care challenge using a practical, consistent strategy based on best practices with Evidence-Based Practice of Critical Care, 3rd Edition. Unique, question-based chapters cover the wide variety of clinical options in critical care, examine the relevant research, and provide recommendations based on a thorough analysis of available evidence. Drs. Clifford S. Deutschman and Patrick J. Nelligan, along with nearly 200 critical-care experts, provide a comprehensive framework for translating evidence into practice, helping both residents and practitioners obtain the best possible outcomes for critically ill patients. Covers a full range of critical care challenges, from routine care to complicated and special situations. Helps you think through each question in a logical, efficient manner, using a practical, consistent approach to available management options and guidelines. Features revised and updated information based on current research, and includes all-new cases on key topics and controversies such as the use/overuse of antibiotics, drug resistance in the ICU, non-invasive mechanical ventilation, frequency of transfusions, and duration of renal replacement therapies. Provides numerous quick-reference tables that summarize the available literature and recommended clinical approaches.
Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens
Author : Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens Publisher : Springer Science & Business Media Page : 278 pages File Size : 53,5 Mb Release : 2011-02-11 Category : Medical ISBN : 9783642008184
Neuroimaging in Dementia by Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens Pdf
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Acute Heart Failure by Alexandre Mebazaa,Mihai Gheorghiade,Faiez Zannad,Joseph E. Parrillo Pdf
For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder by American Psychiatric Association Pdf
The guideline focuses specifically on evidence-based pharmacological treatments for AUD in outpatient settings and includes additional information on assessment and treatment planning, which are an integral part of using pharmacotherapy to treat AUD.
Preventing Chronic Diseases by WHO,World Health Organization Pdf
The major causes of premature adult deaths in all regions of the world, due to chronic diseases such as heart disease, strokes, diabetes and cancer, have been generally neglected on the international health and development agenda. Four out of every five chronic disease-related deaths in the world occur in low and middle income countries, where people tend to develop these diseases at a younger age and to die sooner. The death toll is projected to rise by a further 17 per cent in the next 10 years, whilst child obesity rates are increasing worldwide. This report examines the actual scale and severity of the problem using the most recent data available, considers the major risk factors and associated trends, and discusses the public health policy actions required to implement effective integrated chronic disease prevention and control measures.
