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Author : Kristin Skogstrand,Nis Borbye-Lorenzen,Ulrik Lausten-Thomsen,Marie Bækvad-Hansen
Publisher : Frontiers Media SA
Page : 131 pages
File Size : 43,8 Mb
Release : 2023-03-23
Category : Medical
ISBN : 9782832509791
Author : Bernhard Baune
Publisher : Academic Press
Page : 604 pages
File Size : 46,9 Mb
Release : 2019-10-16
Category : Medical
ISBN : 9780128131770
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Author : Andrew Bush,Robin R Deterding,Albert Li,Felix Ratjen,Peter Sly,Heather Zar,Robert W. Wilmott
Publisher : Elsevier Health Sciences
Page : 1584 pages
File Size : 42,8 Mb
Release : 2023-08-21
Category : Medical
ISBN : 9780323829168
Extensively revised from cover to cover, Kendig and Wilmott's Disorders of the Respiratory Tract in Children, 10th Edition, continues to be your #1 choice for reliable, up-to-date information on all aspects of pediatric respiratory disorders. This highly respected reference is accessible to specialists and primary care providers alike, with coverage of both common and less common respiratory problems found in the newborn and child. Detailed and thorough, this edition covers basic science and its relevance to today’s clinical issues as well as treatment, management, and outcomes information, making it an ideal resource for day-to-day practice as well as certification or recertification review and other professional examinations such as pHERMES. Offers an international perspective on the whole spectrum of the specialty, including a robust video library with demonstrations of key procedures and bronchoscopic views. Uses a consistent format with succinct, bulleted text, and contains abundant tables and figures, chapter summaries, and more than 500 full-color images to convey key information in an easy-to-digest manner. Contains eleven new chapters and discusses timely topics such as big data and -omics in respiratory disease, COVID-19, obesity and its consequences, and vaping and nicotine addiction among children and young people. Provides up-to-date instruction on key procedures, such as bronchoscopy and pulmonary function testing. Highlights the knowledge and expertise of nearly 90 new authors who are global experts in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery.
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services
Publisher : National Academies Press
Page : 85 pages
File Size : 51,9 Mb
Release : 2021-01-15
Category : Medical
ISBN : 9780309682633
As part of the overall disability determination process, the Social Security Administration uses a step-by-step approach to understand how severe an individual's condition is and whether it meets program criteria for disability. The use of various types of biomarkers has been suggested as a way to strengthen the amount and quality of objective evidence available to the review process. At the request of the Social Security Administration, the National Academies of Sciences, Engineering, and Medicine's Board on Health Care Services organized a virtual workshop on July 21, 2020, titled The State of the Science of the Use of Biomarkers to Establish the Presence and Severity of Impairments. Workshop discussions focused on the current and potential uses for biomarkers; explored legal and ethical implications associated with biomarker use in clinical decision making; and considered the possible uses of nongenetic biomarkers as tools for the diagnosis or prognosis of the severity of specific physical and mental impairments. This publication summarizes the presentations and discussion of the workshop.
Author : Judith Pratt,Jeremy Hall
Publisher : Springer
Page : 437 pages
File Size : 46,8 Mb
Release : 2019-01-05
Category : Medical
ISBN : 9783319996424
This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.
Author : Michael Mahler
Publisher : Academic Press
Page : 300 pages
File Size : 41,8 Mb
Release : 2021-03-12
Category : Science
ISBN : 9780323854320
Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Page : 1736 pages
File Size : 51,8 Mb
Release : 2005
Category : Government publications
ISBN : MINN:31951D02480528T
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Page : 1738 pages
File Size : 51,5 Mb
Release : 2005
Category : United States
ISBN : IND:30000106589751
Author : Robert W. Wilmott,Andrew Bush,Robin R Deterding,Felix Ratjen,Peter Sly,Heather Zar,Albert Li
Publisher : Elsevier Health Sciences
Page : 1150 pages
File Size : 48,9 Mb
Release : 2018-01-17
Category : Medical
ISBN : 9780323555951
Now in a fully updated 9th Edition, Kendig's Disorders of the Respiratory Tract in Children, by Drs. Robert Wilmott, Andrew Bush, Robin Deterding, and Felix Ratjen, continues to provide authoritative, evidence-based information to residents, fellows, and practitioners in this wide-ranging specialty. Bringing key knowledge from global experts together in one easy-to-understand volume, it covers everything from the latest basic science and its relevance to today’s clinical issues, to improving patient outcomes for the common and rare respiratory problems found in newborns and children worldwide. Uses succinct, straightforward text, numerous tables and figures, summaries at the end of each chapter, and more than 500 full-color images to convey key information in an easy-to-digest manner. Contains new chapters reflecting expanding knowledge on the respiratory complications of Down syndrome and other genetic disorders, modern molecular therapies for cystic fibrosis and asthma, and pulmonary embolism and thromboembolic disease. Features a new templated format with more descriptive headings and bulleted text for quick reference and navigation. Covers today’s key issues, including the genetic basis of respiratory disease, new and emerging respiratory infections, interstitial lung diseases in infants and young children, technology and diagnostic techniques for pulmonary function tests, emerging lung infections, and new therapies for cystic fibrosis and asthma. Provides up-to-date instruction on important procedures, such as bronchoscopy and pulmonary function testing. Highlights the knowledge and expertise of three new editors, as well as more than 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery.
Author : Robert W. Wilmott,Thomas F. Boat,Andrew Bush,Victor Chernick,Robin R Deterding,Felix Ratjen
Publisher : Elsevier Health Sciences
Page : 1163 pages
File Size : 51,8 Mb
Release : 2012-02-25
Category : Medical
ISBN : 9781455740505
Kendig, Chernick’s Disorders of the Respiratory Tract in Children is the definitive medical reference book to help you confront critical challenges using the latest knowledge and techniques. You’ll get the state-of-the-art answers you need to offer the best care to young patients. Tackle the toughest challenges and improve patient outcomes with coverage of all the common and rare respiratory problems found in newborns and children worldwide. Get a solid foundation of knowledge to better understand and treat your patients through coverage of the latest basic science and its relevance to clinical problems. Get comprehensive, authoritative coverage on today’s hot topics, such as interstitial lung disease, respiratory disorders in the newborn, congenital lung disease, swine flu, genetic testing for disease and the human genome, inflammatory cytokines in the lung, new radiologic techniques, diagnostic imaging of the respiratory tract, and pulmonary function tests. Learn from the experts with contributions from 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, anesthesiology, otolaryngology, allergy, and surgery.
Author : United States. Congress. Senate. Office of Management and Budget. Executive Office of the President
Publisher : Unknown
Page : 1780 pages
File Size : 50,5 Mb
Release : 2016
Category : Economic assistance, Domestic
ISBN : 0160936357
Identifies and describes specific government assistance opportunities such as loans, grants, counseling, and procurement contracts available under many agencies and programs.
Author : Hymie Anisman,Shawn Hayley,Alexander Kusnecov
Publisher : Academic Press
Page : 700 pages
File Size : 50,9 Mb
Release : 2018-07-19
Category : Medical
ISBN : 9780128113523
The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored. Considers both basic human and animal studies that address immunological changes relating to mental health problems across the lifespan Incorporates techniques, concepts and ideas from a variety of social, behavioral and life sciences Explores the relatively new area of the microbiome and how the microbial composition of the gut influences brain function and mental health
Author : Rodrigo Machado-Vieira,Jair Soares
Publisher : Academic Press
Page : 529 pages
File Size : 46,8 Mb
Release : 2022-01-16
Category : Medical
ISBN : 9780128213995
Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder. Describes strategies for the biomarker discovery of relevant proteins differentially expressed in Bipolar Disorder Presents techniques and main findings in transcriptome research related to CNS synaptic function Provides an overview on current behavioral strategies and their validity in drug development in Bipolar Disorder Discusses current genetic findings, integrating tests for treatments leading to personalized treatments
Author : American Psychiatric Association
Publisher : American Psychiatric Publishing
Page : 128 pages
File Size : 40,5 Mb
Release : 2021-09-24
Category : Electronic
ISBN : 1955245185
Author : Michael S. Ritsner
Publisher : Springer Science & Business Media
Page : 247 pages
File Size : 50,7 Mb
Release : 2009-04-21
Category : Medical
ISBN : 9781402098314
Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.