Exercise Autophagy And Chronic Diseases

Author : Ning Chen
Publisher : Springer Nature
Page : 267 pages
File Size : 51,7 Mb
Release : 2021-09-30
Category : Medical
ISBN : 9789811645259

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Exercise, Autophagy and Chronic Diseases by Ning Chen Pdf

This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Author : William J. Rea,Kalpana D. Patel
Publisher : CRC Press
Page : 902 pages
File Size : 50,7 Mb
Release : 2017-12-14
Category : Medical
ISBN : 9781498781374

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Reversibility of Chronic Disease and Hypersensitivity, Volume 5 by William J. Rea,Kalpana D. Patel Pdf

The clinical approaches to the chronic degenerative diseases that drain our resources, and compromise our well-being, have become almost exclusively symptom-focused. The common wisdom is that they are idiopathic with final outcomes to be managed rather than prevented or cured. That they are potentially reversible rarely enters any discussion between doctor and patient. Reversibility of Chronic Disease and Hypersensitivity, Volume 5: Treatment Options of Chemical Sensitivity, the final volume of this set, offers a much different perspective on chronic degenerative disease; one that disputes the idiopathic label attached to most, as well as the usual fatalistic prognosis.

Author : Claude Bouchard
Publisher : Academic Press
Page : 560 pages
File Size : 42,8 Mb
Release : 2015-11-16
Category : Science
ISBN : 9780128039922

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Molecular and Cellular Regulation of Adaptation to Exercise by Claude Bouchard Pdf

Molecular Aspects of Exercise Biology and Exercise Genomics, the latest volume in the Progress in Molecular Biology and Translational Science series includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. Changes in the cellular machinery are described for multiple tissues and organs in terms of signaling pathways, gene expression, and protein abundance. Adaptations to acute exercise as well as exposure to regular exercise are also discussed and considered. Includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise Contains contributions from leading authorities Informs and updates on all the latest developments in the field of exercise biology and exercise genomics

Author : Kunihiro Sakuma
Publisher : BoD – Books on Demand
Page : 488 pages
File Size : 44,5 Mb
Release : 2015-09-02
Category : Technology & Engineering
ISBN : 9789535121565

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Muscle Cell and Tissue by Kunihiro Sakuma Pdf

In order to complete tissue regeneration, various cells such as neuronal, skeletal, smooth, endothelial, and immune (e.g., macrophage) interact smoothly with each other. This book, Muscle Cells and Tissues, offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy in modulating muscle homeostasis and molecular mechanism regulating skeletal muscle mass. The chapters can be interesting for graduate students, postdocs, teachers, physicians, and for executives in biotech and pharmaceutical companies, as well as researchers in the fields of molecular biology and regenerative medicine.

Author : Danik M. Martirosyan
Publisher : D&A Inc.
Page : 280 pages
File Size : 48,5 Mb
Release : 2008-02-10
Category : Medical
ISBN : 0976753545

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Functional Foods for Chronic Diseases (Volume 3) by Danik M. Martirosyan Pdf

The publication of this book serves two great purposes. First, it spreads the word about new functional food products for chronic diseases such as hypertension, diabetes, and obesity to the general public. It not only introduces new functional foods, but also shows the investigations and research that led to their creation. Second, the book preserves the numerous ideas and contributions made in the field. This shows the progress and evolution of this thriving field, with the power to change the lives of millions of people. The forever growing field of functional foods brings together research scientists, food manufacturers and consumers who are committed to this issue through modern achievements of surgical approaches and potential of drug therapy, where particular emphasis is placed on the unresolved problems of pharmaceutical side effects.

Author : Hassane Zouhal,Ismail Laher,Anthony C. Hackney,Urs Granacher,Shunchang Li
Publisher : Frontiers Media SA
Page : 203 pages
File Size : 49,7 Mb
Release : 2022-11-11
Category : Science
ISBN : 9782832505076

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Exercise Physiology and its Role in Chronic Disease Prevention and Treatment - Mechanisms and Insights by Hassane Zouhal,Ismail Laher,Anthony C. Hackney,Urs Granacher,Shunchang Li Pdf

Author : M. A. Hayat
Publisher : Academic Press
Page : 316 pages
File Size : 51,7 Mb
Release : 2015-02-12
Category : Medical
ISBN : 9780128010525

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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by M. A. Hayat Pdf

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections. Volume 7 provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; and the role of autophagy in apoptosis. Attention is given to autophagy in the cardiovascular system, with particular insights into the role of autophagy in atherosclerosis and the distinctive behavior of autophagy in the sinoatrial node. Cutting-edge findings in the relationships between autophagy and lifestyle are explored with the regulation of macroautophagy in response to exercise, as well as the promotion of carcinogenesis via autophagy in response to cigarette smoking. Volume 7 highlights the importance of understanding the role of autophagy in context, as the complexity of autophagic function becomes increasingly clear. Autophagy may be differentially regulated, and may perform distinctive cell-specific functions even within a single tissue. The overall significance of autophagy thus cannot be oversimplified, and must be explored with granular detail of the specific role, function, and area of impact. This book is an asset to newcomers as a concise overview of the complex significance of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. Volumes in the Series

Author : Lawrence H. Lash,Dean P. Jones
Publisher : Elsevier
Page : 528 pages
File Size : 45,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218618

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Mitochondrial Dysfunction by Lawrence H. Lash,Dean P. Jones Pdf

Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Author : Shijun Wang,Jian Wu,Lei-Lei Ma,Yang Li,Haiyang Tang
Publisher : Frontiers Media SA
Page : 245 pages
File Size : 40,5 Mb
Release : 2022-07-27
Category : Medical
ISBN : 9782889766208

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Mitochondrial Metabolism in Ischemic Heart Disease by Shijun Wang,Jian Wu,Lei-Lei Ma,Yang Li,Haiyang Tang Pdf

Author : Matthew W. Martinez
Publisher : Elsevier Health Sciences
Page : 129 pages
File Size : 52,9 Mb
Release : 2022-11-09
Category : Medical
ISBN : 9780323961905

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Sports Cardiology, An Issue of Cardiology Clinics, E-Book by Matthew W. Martinez Pdf

In this issue of Cardiology Clinics, guest editor Dr. Matthew W. Martinez brings his considerable expertise to Sports Cardiology. Top experts in the field cover key topics such as preparticipation sports clearance from a pediatric cardiology perspective; evaluation and treatment of an athlete runner with hypertension; ectopy and the athlete: observation, medication, or intervention; exercise and the HCM guidelines; ECG criteria for athletes; and more. Contains 13 relevant, practice-oriented topics including genetic cardiomyopathies: avoid these common pitfalls; devices and athletics: how to decide who can play; the tactical athlete: definitions, assessment, and management of symptoms; the athlete and vascular conditions: don’t miss these important conditions; myocarditis and exercise: when and how to return to sports; and more. Provides in-depth clinical reviews on sports cardiology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Beverly Rothermel,Abhinav Diwan
Publisher : Elsevier
Page : 456 pages
File Size : 41,8 Mb
Release : 2021-09-22
Category : Science
ISBN : 9780128220047

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Autophagy in Health and Disease by Beverly Rothermel,Abhinav Diwan Pdf

Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspects, including stem cells, embryogenesis, hematopoiesis, and paligenosis. The subsequent sections are devoted to the role of autophagy in specific organ systems involved in metabolic control and diabetes (Chapters 12-15), the cardiovascular system (Chapters 16-18), and the nervous system (Chapters 19-20). The final section (Chapters 21-28) addresses autophagy in other organ systems vital to human health and longevity. Also included are chapters on microautophagy, chaperone-mediated autophagy, and the potential for autophagy as a therapeutic target. Autophagy in Health and Disease is invaluable to anyone new to the field as well as established investigators looking for a broader understanding of autophagy from outside their specific field of study. Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathology Offers extended coverage of the mechanisms that mediate autophagy Covers the role of autophagy in stem cells and induced pluripotent stem cells, as well as the regenerative process of paligenosis Highlights important questions that remain to be addressed

Author : Yannis Dionyssiotis
Publisher : BoD – Books on Demand
Page : 256 pages
File Size : 46,8 Mb
Release : 2017-08-30
Category : Medical
ISBN : 9789535134831

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Frailty and Sarcopenia by Yannis Dionyssiotis Pdf

Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

Author : Pei-Hui Lin
Publisher : MDPI
Page : 322 pages
File Size : 54,9 Mb
Release : 2020-12-15
Category : Science
ISBN : 9783039437818

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Autophagy in Tissue Injury and Homeostasis by Pei-Hui Lin Pdf

Autophagy (“auto-digestion”), a lysosome-dependent process, degrades and turns over damaged or senescent organelles and proteins. Autophagy is a highly regulated process that impacts several vital cellular responses, including inflammation, cell death, energy metabolism, and homeostasis of organelles (mitochondria and others). Although the role of autophagy in the maintenance of tissue homeostasis is well documented, its role during tissue injury and regeneration is still emerging. In this Special Issue on “Autophagy in Tissue Injury and Homeostasis”, we focus on the roles of autophagy in systemic, specific tissue (organs/cells) injury or organ failure associated with sepsis, inflammation, metabolic disorder, toxic chemicals, ischemia-reperfusion injury, hypoxic oxidative stress, tissue fibrosis, trauma, and nutrient starvation. The knowledge gained from the identification and characterization of new molecular mechanisms will shed light on biomedical applications for tissue protection through the modulation of autophagy.

Author : Peter Kokkinos,Christina N. Katsagoni,Labros S. Sidossis
Publisher : John Wiley & Sons
Page : 421 pages
File Size : 52,6 Mb
Release : 2023-04-24
Category : Medical
ISBN : 9781119833444

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Prevention and Management of Cardiovascular and Metabolic Disease by Peter Kokkinos,Christina N. Katsagoni,Labros S. Sidossis Pdf

Prevention and Management of Cardiovascular and Metabolic Disease Provides accurate and well-documented information on the impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases and healthy aging. This authoritative textbook examines the independent and combined impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases, with special emphasis on the elderly populations. In this book the authors: Provide the latest data on the association between a suboptimal diet and physical inactivity and chronic disease. Examine the role of epigenetics on longevity. Discuss the fundamentals of healthy aging. Highlight the role of well-known dietary patterns such as the Mediterranean diet and the Nordic diet in favorable health outcomes, including cardiovascular, metabolic health, and healthy aging. Discuss the health outcomes of physical activity and healthy aging. Present the most recent evidence-based data on the independent and synergistic impact of diet and exercise on disease prevention and management including, heart disease, diabetes mellitus, hypertension, dyslipidemia, kidney failure, cancer and other conditions. Prevention and Management of Cardiovascular and Metabolic Disease: Diet, Physical Activity and Healthy Aging is an excellent textbook for upper-level undergraduate and graduate students in medical and health-related disciplines and for health professionals, including dietitians and nutritionists, exercise physiologists, athletic trainers, nurses, physicians, geriatricians, and other health professionals with a special focus in older adults. This book is also a highly useful reference for health professionals interested in introducing diet and physical activity as an intervention for healthy aging as well as the prevention and management of cardiovascular and other metabolic diseases that are prevalent in aging populations.

Author : Calogero Caruso,Giuseppina Candore
Publisher : Academic Press
Page : 382 pages
File Size : 43,5 Mb
Release : 2021-05-11
Category : Science
ISBN : 9780128227374

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Human Aging by Calogero Caruso,Giuseppina Candore Pdf

Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging Offers the ability to access cross-sectional knowledge more easily Written by expert researchers in biogerontology who are actively involved in various fields within aging research