Exercise Genomics

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Exercise Genomics

Author : Linda S. Pescatello,Stephen M. Roth
Publisher : Springer Science & Business Media
Page : 286 pages
File Size : 50,8 Mb
Release : 2011-03-23
Category : Medical
ISBN : 9781607613558

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Exercise Genomics by Linda S. Pescatello,Stephen M. Roth Pdf

Exercise Genomics encompasses the translation of exercise genomics into preventive medicine by presenting a broad overview of the rapidly expanding research examining the role of genetics and genomics within the areas of exercise performance and health-related physical activity. Leading researchers from a number of the key exercise genomics research groups around the world have been brought together to provide updates and analysis on the key discoveries of the past decade, as well as lend insights and opinion about the future of exercise genomics, especially within the contexts of translational and personalized medicine. Clinicians, researchers and health/fitness professionals will gain up-to-date background on the key findings and critical unanswered questions across several areas of exercise genomics, including performance, body composition, metabolism, and cardiovascular disease risk factors. Importantly, basic information on genomics, research methods, and statistics are presented within the context of exercise science to provide students and professionals with the foundation from which to fully engage with the more detailed chapters covering specific traits. Exercise Genomics will be of great value to health/fitness professionals and graduate students in kinesiology, public health and sports medicine desiring to learn more about the translation of exercise genomics into preventive medicine.

Sports, Exercise, and Nutritional Genomics

Author : Debmalya Barh,Ildus I. Ahmetov
Publisher : Academic Press
Page : 610 pages
File Size : 48,8 Mb
Release : 2019-08-25
Category : Science
ISBN : 9780128163405

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Sports, Exercise, and Nutritional Genomics by Debmalya Barh,Ildus I. Ahmetov Pdf

Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of omics-driven advances across different aspects of exercise and sports physiology, biochemistry, sports medicine, psychology, anthropology, and sports nutrition; and highlighting the opportunities towards advance personalized training and athlete health management. More than 70 international experts from 14 countries have discussed key exercise and sport-related themes through the prism of genomics, epigenomics, transcriptomics, proteomics, metabolomics, telomere biology, talent in sport, individual differences in response to regular physical activity, that in the future may empower coaches, sports physicians, fitness experts, genetic counselors, and translational scientists to employ various omics data and approaches in improving health and physical performance of people participating in sports and exercise activities. Contributors address current knowledge of genetic influence on athletic performance, individual responses to exercise training, as well as the genetics of musculoskeletal phenotypes, exercise-related injuries, flexibility, and neurodegenerative disorders in athletes. Finally, performance-related and psychological traits associated with epigenetic, transcriptomic and metagenomic biomarkers are also considered, along with nutritional and pharmacogenomic aids in sports medicine and personalized nutrition. Effectively synthesizes key themes across molecular aspects of exercise and sports sciences Provides a knowledge base for future translation of omics solutions to talent identification, individualized training, and nutrition Features contributions from international experts (researchers and clinicians) in the subject area

Exercise Genomics

Author : Linda S. Pescatello,Stephen M. Roth
Publisher : Humana Press
Page : 268 pages
File Size : 46,5 Mb
Release : 2011-03-16
Category : Medical
ISBN : 1607613549

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Exercise Genomics by Linda S. Pescatello,Stephen M. Roth Pdf

Exercise Genomics encompasses the translation of exercise genomics into preventive medicine by presenting a broad overview of the rapidly expanding research examining the role of genetics and genomics within the areas of exercise performance and health-related physical activity. Leading researchers from a number of the key exercise genomics research groups around the world have been brought together to provide updates and analysis on the key discoveries of the past decade, as well as lend insights and opinion about the future of exercise genomics, especially within the contexts of translational and personalized medicine. Clinicians, researchers and health/fitness professionals will gain up-to-date background on the key findings and critical unanswered questions across several areas of exercise genomics, including performance, body composition, metabolism, and cardiovascular disease risk factors. Importantly, basic information on genomics, research methods, and statistics are presented within the context of exercise science to provide students and professionals with the foundation from which to fully engage with the more detailed chapters covering specific traits. Exercise Genomics will be of great value to health/fitness professionals and graduate students in kinesiology, public health and sports medicine desiring to learn more about the translation of exercise genomics into preventive medicine.

Genetics Primer for Exercise Science and Health

Author : Stephen M. Roth
Publisher : Human Kinetics
Page : 198 pages
File Size : 40,6 Mb
Release : 2007
Category : Exercise
ISBN : 0736063439

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Genetics Primer for Exercise Science and Health by Stephen M. Roth Pdf

The text maintains a practical focus while providing updates on current research findings and exploring how genetics may affect clinical practice and sport performance training.

Introduction to Genomics

Author : Arthur Lesk
Publisher : Oxford University Press, USA
Page : 421 pages
File Size : 40,9 Mb
Release : 2012
Category : Medical
ISBN : 9780199564354

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Introduction to Genomics by Arthur Lesk Pdf

This book covers the latest techniques that enable us to study the genome in detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism

Genetics and Sports

Author : Malcolm Collins
Publisher : Karger Medical and Scientific Publishers
Page : 209 pages
File Size : 44,6 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9783805590273

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Genetics and Sports by Malcolm Collins Pdf

This publication reviews past, current and future applications of genetic research in the fields of exercise science and sports medicine. It highlights ethical concerns, potential clinical applications and exploitation of genetic information. The authors, an interdisciplinary group of experts comprising clinicians, exercise scientists, human geneticists and other biological scientists, present an integrated and holistic understanding of the field to the reader. Several chapters of the book address the issue of nature and nurture in determining athletic ability and etiology of sports injuries. Other chapters are dealing with genetics and performance research during premolecular and molecular biology eras, gene-lifestyle interactions and their consequences on health, as well as genetic risk factors in musculoskeletal soft tissue injuries. Finally, the possible application of gene therapy in athletes, gene doping and genetic testing of athletes are discussed. The book is highly recommended to exercise scientists, sports clinicians, human geneticists, athletes, coaches and to all those interested in the relatively new area of genetic research within the fields of exercise science and sports medicine.

Computational Genomics with R

Author : Altuna Akalin
Publisher : CRC Press
Page : 462 pages
File Size : 53,9 Mb
Release : 2020-12-16
Category : Mathematics
ISBN : 9781498781862

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Computational Genomics with R by Altuna Akalin Pdf

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Epigenetics of Exercise and Sports

Author : Stuart Raleigh
Publisher : Academic Press
Page : 320 pages
File Size : 45,9 Mb
Release : 2021-07-13
Category : Medical
ISBN : 9780128209370

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Epigenetics of Exercise and Sports by Stuart Raleigh Pdf

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research. Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics Includes preliminary information on exercise epigenetics and covid-19 infection Features chapter contributions from international experts in the field

Routledge Handbook of Sport and Exercise Systems Genetics

Author : J. Timothy Lightfoot,Monica J. Hubal,Stephen M. Roth
Publisher : Routledge
Page : 743 pages
File Size : 51,8 Mb
Release : 2019-03-14
Category : Medical
ISBN : 9781351380157

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Routledge Handbook of Sport and Exercise Systems Genetics by J. Timothy Lightfoot,Monica J. Hubal,Stephen M. Roth Pdf

Technological advances over the last two decades have placed genetic research at the forefront of sport and exercise science. It provides potential answers to some of contemporary sport and exercise’s defining issues and throws up some of the area’s most challenging ethical questions, but to date, it has rested on a fragmented and disparate literature base. The Routledge Handbook of Sport and Exercise Systems Genetics constitutes the most authoritative and comprehensive reference in this critical area of study, consolidating knowledge and providing a framework for interpreting future research findings. Taking an approach which covers single gene variations, through genomics, epigenetics, and proteomics, to environmental and dietary influences on genetic mechanisms, the book is divided into seven sections. It examines state-of-the-art genetic methods, applies its approach to physical activity, exercise endurance, muscle strength, and sports performance, and discusses the ethical considerations associated with genetic research in sport and exercise. Made up of contributions from some of the world’s leading sport and exercise scientists and including chapters on important topical issues such as gene doping, gender testing, predicting sport performance and injury risk, and using genetic information to inform physical activity and health debates, the handbook is a vital addition to the sport and exercise literature. It is an important reference for any upper-level student, researcher, or practitioner working in the genetics of sport and exercise or exercise physiology, and crucial reading for any social scientist interested in the ethics of sport.

History of Exercise Physiology

Author : Charles Tipton
Publisher : Human Kinetics
Page : 608 pages
File Size : 45,8 Mb
Release : 2014-04-01
Category : Science
ISBN : 9781492584391

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History of Exercise Physiology by Charles Tipton Pdf

History of Exercise Physiology brings together leading authorities in the profession to present this first-of-its-kind resource that is certain to become an essential reference for exercise physiology researchers and practitioners. The contributing authors were selected based on their significant contributions to the field, including many examples in which they were part of seminal research. The result of this vast undertaking is the most comprehensive resource on exercise physiology research ever compiled. Exercise physiology research is ongoing, and its knowledge base is stronger than ever. But today’s scholars owe much of their success to their predecessors. The contributors to this book believe it is essential for exercise physiologists to understand the past when approaching the future, and they have compiled this reference to aid in that process. The text includes the following features: • A broad scope of the primary ideas and work done in exercise physiology from antiquity to the present • A review of early contributions to exercise physiology made by Scandinavian scientists, the Harvard Fatigue Laboratory, German laboratories, and the Copenhagen Muscle Research Centre • The incorporation of molecular biology into exercise biology and physiology research that paved the way for exercise physiology • An explanation of the relationship between genomics, genetics, and exercise biology • An integrative view of the autonomic nervous system in exercise • An examination of central and peripheral influences on the cardiovascular system • An in-depth investigation and analysis of how exercise influences the body’s primary systems •A table in most chapters highlighting the significant research milestones Well illustrated with figures and photos, History of Exercise Physiology helps readers understand the research findings and meet the most prominent professionals in the field. From studying great thinkers of antiquity and cutting-edge work done by pioneers at research institutions, to exploring the inner workings of all the body’s systems, researchers will gain a precise understanding of what happens when human bodies move—and who influenced and furthered that understanding.

Genetics and Sports

Author : Michael Posthumus,Malcolm Collins
Publisher : Unknown
Page : 0 pages
File Size : 52,6 Mb
Release : 2016
Category : Medical
ISBN : 3318030104

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Genetics and Sports by Michael Posthumus,Malcolm Collins Pdf

This second edition of Genetics and Sports expands on topics previously discussed in an attempt to create an integrated and holistic understanding of the field of sports genomics. It is an update on technologies and on the role of genetics in training, performance, injury, and other exercise-related phenotypes. Ethical concerns and the importance of counselling before and after genetic testing are also addressed. It is increasingly important to understand the field of genetics and sports because of the potential to use and misuse information. All exercise scientists, sport and exercise clinicians, athletes, and coaches need to be adequately informed to ensure that genetic information is accurately and properly used. Genetics and Sports is, therefore, highly recommended to all of these groups.

Recent Advances in Nutrigenetics and Nutrigenomics

Author : Anonim
Publisher : Academic Press
Page : 518 pages
File Size : 45,7 Mb
Release : 2012-06-19
Category : Technology & Engineering
ISBN : 9780123984050

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Recent Advances in Nutrigenetics and Nutrigenomics by Anonim Pdf

This volume of Progress in Molecular Biology and Translational Science covers the recent advances in the expanding fields of nutrigenetics and nutrigenomics. Forty authors from eight countries have contributed to the publication, representing the most cutting-edge research available. Contributions from leading authorities Informs and updates on all the latest developments in the field

The Encyclopaedia of Sports Medicine, Genetic and Molecular Aspects of Sports Performance

Author : Claude Bouchard,Eric P. Hoffman
Publisher : John Wiley & Sons
Page : 584 pages
File Size : 41,5 Mb
Release : 2011-08-02
Category : Medical
ISBN : 9781444348293

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The Encyclopaedia of Sports Medicine, Genetic and Molecular Aspects of Sports Performance by Claude Bouchard,Eric P. Hoffman Pdf

This is the latest volume in the IOC Encyclopaedia of Sports Medicine series, summarizing the evidence from all relevant sources on the genetic and molecular basis of sports and other human physical performance. The initial chapters address the basic science of genomics and genetics and the regulation of gene expression. Additional chapters provide authoritative information on the genetics of complex performance phenotypes, the contributions of small animal research, family and twin studies, and ethnic comparisons. A final section addresses the issue of the contribution of specific genes and molecular markers as related to endurance, strength and power, and responsiveness to specific conditioning programs. This latest volume in the Encyclopaedia of Sports Medicine Series from the Medical Commission of the International Olympic Committee is a must for sports and exercise scientists who require a thorough guide to the most cutting edge science in this expanding field.

Molecular Exercise Physiology

Author : Adam Sharples,Henning Wackerhage,James Morton
Publisher : Taylor & Francis
Page : 359 pages
File Size : 53,9 Mb
Release : 2022-05-11
Category : Science
ISBN : 9781351617017

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Molecular Exercise Physiology by Adam Sharples,Henning Wackerhage,James Morton Pdf

Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research in epigenetics and muscle memory, satellite cells, exercise in cancer, at altitude, and in hot and cold climates. Chapters include learning objectives, structured guides to further reading, review questions, overviews of work by key researchers and box discussions from important pioneers in the field, making it a complete resource for any molecular exercise physiology course. The book includes cell and molecular biology laboratory methods for dissertation and research projects in molecular exercise physiology and muscle physiology. This book is essential reading for upper-level undergraduate or postgraduate courses in cellular and molecular exercise physiology and muscle physiology. It is a valuable resource for any student with an advanced interest in exercise physiology in both sport performance and clinical settings.

Genetics of Fitness and Physical Performance

Author : Claude Bouchard,Robert M. Malina,Louis Pérusse
Publisher : Human Kinetics
Page : 416 pages
File Size : 47,9 Mb
Release : 1997
Category : Education
ISBN : 0873229517

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Genetics of Fitness and Physical Performance by Claude Bouchard,Robert M. Malina,Louis Pérusse Pdf

Genetics of Fitness and Physical Performance is the first comprehensive reference on the role of the genes in influencing individual variation in fitness and performance. This essential compendium reviews the past 25 years of accumulated evidence on the genetic basis of health- and performance-related fitness phenotypes. Focusing on the interests of sport scientists, the authors provide insight into the significance of this research on nearly every aspect of the study of human physical activity. The book presents the biological basis of heredity and explains the concepts and methods of genetic epidemiology and molecular biology that are necessary to understand this specialized field. With the rapid advances in molecular biology and the paradigms of human genetics, exercise scientists face a dynamic and vibrant new field. This book offers readers new opportunities to better understand atherosclerosis, noninsulin dependent diabetes, obesity, and hypertension by searching for single gene effects and identifying susceptibility genes. The authors review the evidence on the role of the genes for human traits as it pertains to the exercise science field. And they explore the scientific, practical, and ethical issues that confront exercise scientists as progress is made in this field. Genetics of Fitness and Physical Performance is vital reading for scholars in the field of exercise and sport science to understand how recent discoveries in genetics might shape their future research.