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Author : Franco M. Muggia
Publisher : Unknown
Page : 271 pages
File Size : 45,9 Mb
Release : 1985
Category : Cancer
ISBN : 9024724260
Author : Franco M Muggia
Publisher : Unknown
Page : 288 pages
File Size : 50,9 Mb
Release : 1985-02-28
Category : Electronic
ISBN : 1461325641
Author : Franco M. Muggia
Publisher : Springer Science & Business Media
Page : 235 pages
File Size : 50,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461317470
Experimental chemotherapy continues to be at the forefront of cancer thera peutics. Topics covered in the preceding volume on cancer chemotherapy in this series such as study of drugs by alkaline elution, the development of the antimetabolite tiazofurin, and the treatment of germ cell tumors have become informative references to current experimentalists and practitioners. In even earlier volumes, reviews of the platinum compounds, anthracyclines, and osteosarcoma represent topics associated with such rapid progress requiring a look back to provide the appropriate perspective. Similarly, we venture to predict that the topics in this volume will become useful landmarks for future drug development and disease strategies. In the area of drug development, what is being learned about old, estab lished antineoplastics is raising renewed expectations that it will be translated into improved applications and patient benefit. For example, we now have the ability to modulate the action of alkylating agents and fluorinated pyri midines to achieve greater sensitivity. A new compound for an old target, trimetrexate, an antifolate that does not polyglutaminate, will have a role not only in treatment of neoplastic diseases, but also protozoal infection.
Author : Roland Mertelsmann
Publisher : Springer Science & Business Media
Page : 197 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642760372
Recent experimental and clinical progress in the evaluation of cytokines in treatment concepts for cancer patients is the central theme of this book in the ESO Monographs series. The discussion revolves on the experimental basis as well as current clinical experience with the use of human recombinant cytokines. It gives the state of the art and, as such, puts into perspective potential areas of growth and future research.
Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
Publisher : National Academies Press
Page : 151 pages
File Size : 55,6 Mb
Release : 2010-10-22
Category : Medical
ISBN : 9780309163354
An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
Author : Anonim
Publisher : Unknown
Page : 46 pages
File Size : 45,9 Mb
Release : 1961
Category : Cancer
ISBN : UOM:39015030896206
Author : P. Banzet,J.F. Holland,D. Khayat,M. Weil
Publisher : Springer Science & Business Media
Page : 905 pages
File Size : 44,8 Mb
Release : 2013-12-14
Category : Medical
ISBN : 9782817807652
This book gathers the educational lectures and the texts of the main presenta tions given at the 4th International Congress on Anticancer Chemotherapy which took place in February 1993 in Paris and was attended by 5 000 oncologists from all continents, physicians, students and nurses. This book aspires to give update of the most scientific and clinical aspects of modern oncology. It aims also at showing the prospects that are opened by the rapid progress of cancer biology. The editors are grateful to the authors whose scholarship de fines the quality of the book. Educational lectures The pathogenesis of human cancer metastasis I] Fidler Cancer is a collection of malignancies with each cancer of each organ consist ing of numerous subsets. This biologic and clinical heterogeneity is probably due to the different etiologies, origins, and selection pressures. Despite this heterogeneity, all malignant neoplasms have a uniform characteristic : the ability to invade host tissues and produce metastases. Clinical observations of cancer patients and studies with experimental rodent tumors have revealed that cer tain tumors produce metastasis to specific organs independent of vascular anat omy, rate of blood flow, and number of tumor cells delivered to each organ. The distribution and fate of hematogeneously disseminated, radiolabelled tumor cells in experimental rodent systems amply demonstrate that tumor cells reach the microvasculature of many organs.
Author : B. H. Morrison
Publisher : Unknown
Page : 320 pages
File Size : 47,5 Mb
Release : 1960
Category : Antineoplastic agents
ISBN : UOM:39015057743034
Author : B. H. Morrison
Publisher : Unknown
Page : 0 pages
File Size : 46,5 Mb
Release : 1960
Category : Antineoplastic agents
ISBN : OCLC:3589710
Author : Institute of Medicine,Committee on Technological Innovation in Medicine
Publisher : National Academies Press
Page : 225 pages
File Size : 41,9 Mb
Release : 1991-02-01
Category : Medical
ISBN : 9780309044912
Americans praise medical technology for saving lives and improving health. Yet, new technology is often cited as a key factor in skyrocketing medical costs. This volume, second in the Medical Innovation at the Crossroads series, examines how economic incentives for innovation are changing and what that means for the future of health care. Up-to-date with a wide variety of examples and case studies, this book explores how payment, patent, and regulatory policiesâ€"as well as the involvement of numerous government agenciesâ€"affect the introduction and use of new pharmaceuticals, medical devices, and surgical procedures. The volume also includes detailed comparisons of policies and patterns of technological innovation in Western Europe and Japan. This fact-filled and practical book will be of interest to economists, policymakers, health administrators, health care practitioners, and the concerned public.
Author : Tomasz M. Beer,Larry Axmaker
Publisher : Diamedica
Page : 0 pages
File Size : 41,8 Mb
Release : 2012
Category : Cancer
ISBN : 098232197X
A readable guide for anyone who is considering therapeutic options in addition to standard cancer therapy. The book seeks to share knowledge about cancer clinical trials with people living with cancer, their families and loved ones.
Author : Franco M. Muggia
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 48,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461325635
As in CANCER CHEMOTHERAPY 1, this volume brings to the reader highlights in three different areas of cancer therapeutics: new concepts and models; drug classes; and clinical settings. Topics were chosen because of their timeliness or probable current impact in cancer treatment. Authors were selected on the basis of their ability to provide a critical overview of specific subjects and their involvement in original work. I shall review the aims of this second volume, and then elaborate on the scope of its con tents. The principal aim of the volumes on cancer chemotherapy in the' Cancer Treatment and Research' series, as stated in the preface to the first volume, is to assemble in a concentrated form selected ingredients of chemothera peutic progress. These ingredients are to include concepts in therapeutic strategy, pre-clinical studies, development of major classes of compounds, identificatlon of new directions and of landmarks of clinical progress. Thus we do not foresee overlap with series which provide an yearly update of chemotherapy in an encyclopedic manner, or reviews of cancer chemother apy. Unlike those publications, our volumes are not intended to seek a place in shelves as a reference manual. It is this Editor's hope that persons repre senting various biomedical disciplines will seek the' Cancer Treatment and Research' chemotherapy volumes to survey advances in the field at regular intervals.
Author : Xu Ze,Xu Jie,Bin Wu
Publisher : AuthorHouse
Page : 329 pages
File Size : 46,7 Mb
Release : 2018-06-28
Category : Medical
ISBN : 9781546247593
In the half century after the Second World War, oncology has developed greatly both in the world and in China. There are three traditional major treatments: surgery, which has been used to treat tumors for more than a hundred years; radiotherapy, which has been used for ninety years; and chemotherapy, which has been used for nearly seventy years. In the 1980s, there was the rise of biological therapy and immunotherapy. The effects of oncological therapy have made a lot of progress. Many tumors have achieved good results, but there are still many solid tumors whose efficacy are still very poor. In 1985, the author followed up more than three thousand patients who had undergone the general surgical operation and thorax surgical operation. The results showed that most patients relapsed and metastasized within two to three years after surgery. Some patients even relapsed in a few months. This made me deeply realize that surgery is successful and standardized, but the long-term effect is not satisfied or that the long-term treatment is a failure.
Author : David Khayat,Gabriel N. Hortobagyi
Publisher : Unknown
Page : 0 pages
File Size : 49,6 Mb
Release : 1999
Category : Antineoplastic agents
ISBN : 3540596666
Author : Enrico Mihich,Sándor Eckhardt
Publisher : S. Karger AG (Switzerland)
Page : 192 pages
File Size : 41,6 Mb
Release : 1980-01-01
Category : Antineoplastic agents
ISBN : 380550411X
