Exploring The Potential Of Particle Radiotherapy Helium Neutrons Carbon And Other Heavy Ions

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Carbon-Ion Radiotherapy

Author : Hirohiko Tsujii,Tadashi Kamada,Toshiyuki Shirai,Koji Noda,Hiroshi Tsuji,Kumiko Karasawa
Publisher : Springer Science & Business Media
Page : 312 pages
File Size : 54,9 Mb
Release : 2013-12-25
Category : Medical
ISBN : 9784431544579

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Carbon-Ion Radiotherapy by Hirohiko Tsujii,Tadashi Kamada,Toshiyuki Shirai,Koji Noda,Hiroshi Tsuji,Kumiko Karasawa Pdf

This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.

Principles and Practice of Particle Therapy

Author : Timothy D. Malouff,Daniel M. Trifiletti
Publisher : John Wiley & Sons
Page : 563 pages
File Size : 42,5 Mb
Release : 2022-05-19
Category : Medical
ISBN : 9781119707523

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Principles and Practice of Particle Therapy by Timothy D. Malouff,Daniel M. Trifiletti Pdf

Principles and Practice of Particle Therapy Although radiation has been used therapeutically for over 100 years, the field of radiation oncology is currently in the midst of a renaissance, particularly with regards to the therapeutic use of particles. Over the past several years, access to particle therapy, whether it be proton therapy or other heavy ion therapy, has increased dramatically. Principles and Practice of Particle Therapy is a clinically oriented resource that can be referenced by both experienced clinicians and those who are just beginning their venture into particle therapy. Written by a team with significant experience in the field, topics covered include: Background information related to particle therapy, including the clinically relevant physics, radiobiological, and practical aspects of developing a particle therapy program “Niche” treatments, such as FLASH, BNCT, and GRID therapy The simulation process, target volume delineation, and unique treatment planning considerations for each disease site Less commonly used ions, such as fast neutrons or helium Principles and Practice of Particle Therapy is a go-to reference work for any health professional involved in the rapidly evolving field of particle therapy.

Proton Therapy Physics

Author : Harald Paganetti
Publisher : CRC Press
Page : 691 pages
File Size : 42,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439836453

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Proton Therapy Physics by Harald Paganetti Pdf

Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Mitteilungen

Author : International Cancer Congress
Publisher : Unknown
Page : 340 pages
File Size : 55,6 Mb
Release : 1979
Category : Cancer
ISBN : UOM:39015001639882

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Mitteilungen by International Cancer Congress Pdf

Clinical Challenges in Therapeutic Drug Monitoring

Author : William Clarke,Amitava Dasgupta
Publisher : Elsevier
Page : 376 pages
File Size : 45,7 Mb
Release : 2016-07-21
Category : Medical
ISBN : 9780128020524

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Clinical Challenges in Therapeutic Drug Monitoring by William Clarke,Amitava Dasgupta Pdf

Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window

Applied Nuclear Physics at Accelerators

Author : Marco Durante,Vincenzo Patera,Yolanda Prezado
Publisher : Frontiers Media SA
Page : 728 pages
File Size : 52,5 Mb
Release : 2021-07-14
Category : Medical
ISBN : 9782889710393

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Applied Nuclear Physics at Accelerators by Marco Durante,Vincenzo Patera,Yolanda Prezado Pdf

Nuclear Physics

Author : National Research Council,Division on Engineering and Physical Sciences,Board on Physics and Astronomy,Committee on the Assessment of and Outlook for Nuclear Physics
Publisher : National Academies Press
Page : 276 pages
File Size : 43,5 Mb
Release : 2013-02-25
Category : Science
ISBN : 9780309260435

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Nuclear Physics by National Research Council,Division on Engineering and Physical Sciences,Board on Physics and Astronomy,Committee on the Assessment of and Outlook for Nuclear Physics Pdf

The principal goals of the study were to articulate the scientific rationale and objectives of the field and then to take a long-term strategic view of U.S. nuclear science in the global context for setting future directions for the field. Nuclear Physics: Exploring the Heart of Matter provides a long-term assessment of an outlook for nuclear physics. The first phase of the report articulates the scientific rationale and objectives of the field, while the second phase provides a global context for the field and its long-term priorities and proposes a framework for progress through 2020 and beyond. In the second phase of the study, also developing a framework for progress through 2020 and beyond, the committee carefully considered the balance between universities and government facilities in terms of research and workforce development and the role of international collaborations in leveraging future investments. Nuclear physics today is a diverse field, encompassing research that spans dimensions from a tiny fraction of the volume of the individual particles (neutrons and protons) in the atomic nucleus to the enormous scales of astrophysical objects in the cosmos. Nuclear Physics: Exploring the Heart of Matter explains the research objectives, which include the desire not only to better understand the nature of matter interacting at the nuclear level, but also to describe the state of the universe that existed at the big bang. This report explains how the universe can now be studied in the most advanced colliding-beam accelerators, where strong forces are the dominant interactions, as well as the nature of neutrinos.

Cancer Management in Man

Author : Alfred L. Goldson
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400925366

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Cancer Management in Man by Alfred L. Goldson Pdf

Previous volumes in this series have discussed the current progression have identified a variety of targets and strategies state of our knowledge concerning the pathophysiology of to allow these goals to be realized. This volume critically cancer growth and progression. The complexity of the in reviews approaches towards cancer management in man at teraction of malignant neoplasms and the host, the the levels of: detection, diagnosis, surgery, radiology, heterogeneity of malignant cell subpopulations, and the chronobiology and endocrine treatment. existence of metastatic tumor cells resistant to drug thera Several chapters review selected methods of cancer diag pies remain as significant clinical challenges to clinical on nosis. In addition, a variety of on-going and novel ap cologists. Indeed, conventional treatment regimens of che proaches for cancer treatment are also presented in this volume. Progress in the early detection of malignant neo motherapy, surgery and radiology are often ineffective for the therapy of a large variety of established metastatic can plasms, coupled with novel approaches for the therapy of cer in patients. When one considers the insidiousness of such neoplasms, may ultimately yield safe and well-tolerated agents for the selective therapy of solid malignancies. New progressive neoplastic growth and the emergence of con tinuously more aggressive and malignant cellular subpop therapeutic approaches, directed towards the biochemical ulations one is overwhelmed with the challenges inherent in and molecular targets identified in the earlier volumes of this series, may ultimately lead to the generation of new mo attempting to control malignant neoplasms.

Research Awards Index

Author : Anonim
Publisher : Unknown
Page : 1380 pages
File Size : 47,6 Mb
Release : 1977
Category : Medicine
ISBN : MINN:30000008789137

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Research Awards Index by Anonim Pdf

Radiation and Health

Author : Thormod Henriksen
Publisher : CRC Press
Page : 241 pages
File Size : 55,5 Mb
Release : 2002-09-05
Category : Science
ISBN : 9780203166352

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Radiation and Health by Thormod Henriksen Pdf

Radiation and the effects of radioactivity have been known for more than 100 years. International research spanning this period has yielded a great deal of information about radiation and its biological effects and this activity has resulted in the discovery of many applications in medicine and industry including cancer therapy, medical diagnostics

Proton and Carbon Ion Therapy

Author : C-M Charlie Ma,Tony Lomax
Publisher : CRC Press
Page : 258 pages
File Size : 50,5 Mb
Release : 2012-10-09
Category : Science
ISBN : 9781439816073

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Proton and Carbon Ion Therapy by C-M Charlie Ma,Tony Lomax Pdf

Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.

Textbook of Radiation Oncology

Author : Steven A. Leibel,Theodore L. Phillips
Publisher : Unknown
Page : 0 pages
File Size : 44,5 Mb
Release : 2004
Category : Medical
ISBN : 0721600263

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Textbook of Radiation Oncology by Steven A. Leibel,Theodore L. Phillips Pdf

Thoroughly revised and updated, the 2nd Edition presents all of the latest advances in the field, including the most recent technologies and techniques. For each tumor site discussed, readers will find unparalleled coverage of multiple treatment plans, histology and biology of the tumor, its anatomic location and routes of spread, and utilization of specialized techniques. This convenient source also reviews all of the basic principles that underlie the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, intraoperative irradation, and more. Comprehensively reviews each topic, with a distinct clinical orientation throughout. Serves as a foundation for the basic principles that underlie the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, intraoperative irradation, and more. Guides readers through all stages of treatment application with step-by-step techniques for the assessment and implementation of radiotherapeutic options. Presents latest information on brachytherapy * 3-dimensional conformal treatment planning * sterotactic radiosurgery * and radiolabeled antibodies. Discusses the recent use of radiotherapy in the treatment of primary lymphoma, leukemia, multiple myeloma, and cancers of the prostate and central nervous system. Includes the latest AJCC staging system guidelines. Offers the latest advances in techniques, allowing you to deliver doses precisely to areas affected by malignancy and spare healthy tissue. Presents new chapters on the hottest topics including Three Dimensional Conformal Radiotherapy * Intensity Modulated Radiotherapy * Breathing Synchronized Radiotherapy * Plasma Cell Tumors: Multiple Myeloma and Solitary Plasmacytoma * Extracranial Stereotactic Radioablation * and [Imaging of the] Head and Neck * Thorax * Abdomen * and Pelvis.

INIS Atomindex

Author : Anonim
Publisher : Unknown
Page : 1336 pages
File Size : 50,8 Mb
Release : 1984
Category : Nuclear energy
ISBN : STANFORD:36105021588913

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INIS Atomindex by Anonim Pdf

IASLC Thoracic Oncology E-Book

Author : Harvey Pass,David Ball,Giorgio Scagliotti
Publisher : Elsevier Health Sciences
Page : 960 pages
File Size : 53,9 Mb
Release : 2017-04-21
Category : Medical
ISBN : 9780323527842

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IASLC Thoracic Oncology E-Book by Harvey Pass,David Ball,Giorgio Scagliotti Pdf

Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today’s best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. Features a new full-color design throughout, as well as updated diagnostic algorithms.