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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011. Presents the transformations experienced by the domains of innate immunity Shows the lineage of these results Bridges the gap between innate immunity of invertebrates and that of vertebrates
Kuby Immunology by Jenni Punt,Sharon Stranford,Patricia Jones,Judy Owen Pdf
Janis Kuby’s groundbreaking introduction to immunology was the first textbook for the course actually written to be a textbook. Like no other text, it combined an experimental emphasis with extensive pedagogical features to help students grasp basic concepts. Now in a thoroughly updated new edition, Kuby Immunology remains the only undergraduate introduction to immunology written by teachers of the course. In the Kuby tradition, authors Jenni Punt, Sharon Stranford, Patricia Jones, and Judy Owen present the most current topics in an experimental context, conveying the excitement of scientific discovery, and highlight important advances, but do so with the focus on the big picture of the study of immune response, enhanced by unsurpassed pedagogical support for the first-time learner. Punt, Stranford, Jones, and Owen bring an enormous range of teaching and research experiences to the text, as well as a dedication to continue the experiment-based, pedagogical-driven approach of Janis Kuby. For this edition, they have worked chapter by chapter to streamline the coverage, to address topics that students have the most trouble grasping, and to continually remind students where the topic at hand fits in the study of immunology as a whole.
Microbiology by Nina Parker,OpenStax,Mark Schneegurt,AnhHue Thi Tu,Brian M. Forster,Philip Lister Pdf
"Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs. Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology."--BC Campus website.
Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf
Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
Enterprise Risk Management in a Nutshell by Dennis Cox Pdf
Risk management is an often-used phrase that is rarely fully embedded within the business process and procedures of firms. This book looks at the challenges faced in implementing a risk management framework as well as the key elements of such a framework. It is designed for the business professional that is not an expert in risk management and addresses all of the major risks that are likely to be faced in practice, considering the risk mitigation and measurement techniques that are most likely to be relevant. This is an intermediate book and accordingly does not focus on the mathematical elements but rather provides a readable entry text for anyone seeking information on this important subject.
Author : Center for the Study of Intelligence (U.S.) Publisher : Unknown Page : 104 pages File Size : 46,6 Mb Release : 1996 Category : Electronic government information ISBN : IND:30000067699839
Virginia Attorney General Ken Cuccinelli leads the historic fight against the unprecedented overreach of the federal government. With Obamacare and agencies like the EPA, the FCC, and the National Labor Relations Board attempting to exercise unprecedented control over the American people, the Obama Administration was breaking federal laws, ignoring federal courts, and violating the Constitution to achieve its goals of redistributing wealth, concentrating power in Washington, and rewarding its supporters. Without enough lawmakers in Washington devoted to protecting the rule of law to stop the federal government's liberty-stealing power grab, the battle had to be waged in an unprecedented way: from the states -- just as our Founding Fathers intended. The man who led the charge was Ken Cuccinelli, the first state attorney general to argue in federal court against Obamacare, an unapologetic defender of the Constitution, and a man admirers and detractors alike said "was tea party long before there was a Tea Party." The Last Line of Defense provides a behind-the-scenes account of the myriad of legal battles in which our states were the only instruments of resistance to federal abuses of power. It is a must-read for every patriot.
This paper is a case study in the wartime evolution of tactical doctrine. Besides providing a summary of German Infantry tactics of the First World War, this study offers insight into the crucial role of leadership in facilitating doctrinal change during battle. It reminds us that success in war demands extensive and vigorous training calculated to insure that field commanders understand and apply sound tactical principles as guidelines for action and not as a substitute for good judgment. It points out the need for a timely effort in collecting and evaluating doctrinal lessons from battlefield experience. --Abstract.
Oh, Great! I was Reincarnated as a Farmer by Benjamin Neihana Kerei Pdf
What do you have when you blend a pinch of litrpg, a touch of farming simulator, a sprinkle of epic fantasy, a whole cup of Isekai, and a dash of Home Alone? You have Arnold's life. Accidentally murdered by a cleric in another universe during a botched resurrection, Arnold, a semi-pro gamer, wakes upon an altar to find himself incarnated into the overweight body of a farmer who could have been his fatter twin. He's not the hero. He's not the villain. He's certainly not the chosen one who is there to save the world. He's a clerical error. It could be a bad joke, but apparently, it happens so often that they have a standard procedure for returning you. That standard procedure doesn't apply to Arnold. Now stuck on a new earth, in a new universe, with no way home, Arnold must use his gaming skills to figure out how to level his farmer class to 100 and gain a second class which doesn't make him want to beat his head against the wall. There is just one small problem: farmers don't gain experience from killing monsters. Like at all. Follow Arnold on his hilarious journey as he stubbornly comes to grips with his new reality and tries to change his destiny from that of your typical farmer.
Non-canonical Cyclic Nucleotides by Roland Seifert Pdf
The cyclic purine nucleotides 3’,5’-cAMP and 3’,5’-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume 191). In addition to 3’,5’-cAMP and 3’,5’-cGMP, so-called non-canonical cyclic nucleotides exist. These comprise the cyclic pyrimidine nucleotides 3’,5’-cCMP and 3’,5’-cUMP, the purine nucleotide 3’,5’-cIMP, the 2’,3’-nucleoside monophosphates and cyclic dinucleotides. In this volume of the Handbook of Pharmacology, word-leading experts in the field summarize our current knowledge on these non-canonical cyclic nucleotides, discuss open questions, future research directions and the pharmacotherapeutic implications. Special emphasis will be given to the emerging roles of 3’,5’-cCMP and 3’,5’-cUMP as second messengers with regard to generators, effectors, biological functions, inactivation and bacterial toxins. The role of 3’,5’-cIMP as potential second messenger will also be critically discussed. Furthermore, we will consider transport of cyclic nucleotides and their potential role as first messengers. The role of the cyclic dinucleotide cGAMP in the immune system will covered, too. Lastly, the book will present important methodological aspects ranging from mass-spectrometric methods for cyclic nucleotide detection to the synthesis of nucleotide analogs as experimental tools and holistic methods for analysis of cyclic nucleotide effects.
A modeler’s guide to one of the most powerful tanks operating today: “Highly recommended.” —AMPS Indianapolis When the Leopard 2, a third-generation main battle tank, first entered service with the Bundeswehr in 1979, at the height of the Cold War, it was indisputably the most advanced and potent tank in the world. Over four decades it has undergone numerous upgrades and modifications to ensure it remains one of the most powerful tanks operating today. It currently serves with the armies of seventeen nations, from Canada to Turkey and many European states. The Leopard 2 is also a popular subject for modelers, which is why David Grummitt’s highly illustrated expert guide is so valuable. As well as describing in detail the Leopard 2’s design, development, and combat history, he gives a full account of the wide range of modeling kits and accessories available in all the popular scales. Included is a modeling gallery, which features six builds covering a range of Leopard 2s serving with different nations and a section of large-scale color profiles which provide both reference and inspiration for modelers and military enthusiasts alike.