Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Molecular Biology of The Cell
Bruce Alberts
Innate Immunity
Innate Immunity Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Innate Immunity book. This book definitely worth reading, it is an incredibly well-written.
The Innate Immune System
Tom Monie
Author : Tom Monie
Publisher : Academic Press
Page : 228 pages
File Size : 43,8 Mb
Release : 2017-02-16
Category : Medical
ISBN : 9780081007587
The Innate Immune System by Tom Monie Pdf
The Innate Immune System: A Compositional and Functional Perspective focuses on the components and functionality of the innate immune system, detailing how they work in their own right, and then progressing to cover their relevance to disease and how they interface with the adaptive response. Despite the growing appreciation of the importance of the innate immune system, many classical immunology books still focus predominantly on the adaptive immune response. Not only is this unbalanced, but it fails to reflect the growing synergy between the activation and function of the innate response and the final nature of adaptive response. This book fills the gap in knowledge that is needed to fully understand and appreciate the topic. Provides a clear, but simple picture of the main principle of innate immunity and the interlink with adaptive responses Fulfills an unmet need in the area of innate immunity Gives a constructive and progressive approach to introducing and explaining the key players in the innate immune response Introduces and explains the key players in the innate immune response with a constructive and progressive approach Presents the components of the innate response and shows how these interrelated areas connect with one another from a functional perspective Enables the reader to gradually increase their level of understanding and knowledge without the risk of becoming confused, thereby ensuring they fully comprehend the integrated signaling pathways
Janeway's Immunobiology
Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 55,7 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570
Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Innate Immunity: Resistance and Disease-Promoting Principles
G. Hartmann,H. Wagner
Author : G. Hartmann,H. Wagner
Publisher : Karger Medical and Scientific Publishers
Page : 140 pages
File Size : 55,5 Mb
Release : 2013-06-05
Category : Medical
ISBN : 9783318023480
Innate Immunity: Resistance and Disease-Promoting Principles by G. Hartmann,H. Wagner Pdf
Our understanding of the complex innate immune response is increasing rapidly. Its role in the protection against viral or bacterial pathogens is essential for the survival of an organism. However, it is equally important to avoid unregulated inflammation because innate immune responses can cause or promote chronic autoinflammatory diseases such as gout, atherosclerosis, type 2 diabetes or certain aspects of the metabolic syndrome. In this book leading international experts in the field of innate immunity share their findings, define the ‚state of the art‘ in this field and evaluate how insight into the molecular basis of these diseases could help in the design of new therapies. A tremendous amount of work on the innate immune response has been done over the last fifteen years, culminating in the 2011 Nobel Prize in Physiology/Medicine awarded for the discoveries of Toll genes in immunity in flies, membrane-bound Toll-like receptors in mammals, and dendritic cells as initiators of adaptive immunity.
The Innate Immune Response to Noninfectious Stressors
Massimo Amadori
Author : Massimo Amadori
Publisher : Academic Press
Page : 276 pages
File Size : 51,7 Mb
Release : 2016-02-23
Category : Medical
ISBN : 9780128019740
The Innate Immune Response to Noninfectious Stressors by Massimo Amadori Pdf
The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation. Provides insights into the fundamental homeostatic processes vis-à-vis stressors to help in investigation Illustrates the depicted tenets and how to offset them against established models of response to physical and psychotic stressors in both animals and humans Covers the crucial issue of the immune response to endocrine disruptors Includes immunological parameters as reporter system of environmental adaptation Provides many illustrative examples to foster reader understanding
Plant Innate Immunity Signals and Signaling Systems
P. Vidhyasekaran
Author : P. Vidhyasekaran
Publisher : Springer Nature
Page : 276 pages
File Size : 50,6 Mb
Release : 2020-04-15
Category : Science
ISBN : 9789402419405
Plant Innate Immunity Signals and Signaling Systems by P. Vidhyasekaran Pdf
The volume III of the book presents the ways and means to manipulate the signals and signaling system to enhance the expression of plant innate immunity for crop disease management. It also describes bioengineering approaches to develop transgenic plants expressing enhanced disease resistance using plant immunity signaling genes. It also discusses recent commercial development of biotechnological products to manipulate plant innate immunity for crop disease management. Engineering durable nonspecific resistance to phytopathogens is one of the ultimate goals of plant breeding. However, most of the attempts to reach this goal fail as a result of rapid changes in pathogen populations and the sheer diversity of pathogen infection mechanisms. Recently several bioengineering and molecular manipulation technologies have been developed to activate the ‘sleeping’ plant innate immune system, which has potential to detect and suppress the development of a wide range of plant pathogens in economically important crop plants. Enhancing disease resistance through altered regulation of plant immunity signaling systems would be durable and publicly acceptable. Strategies for activation and improvement of plant immunity aim at enhancing host’s capability of recognizing invading pathogens, boosting the executive arsenal of plant immunity, and interfering with virulence strategies employed by microbial pathogens. Major advances in our understanding of the molecular basis of plant immunity and of microbial infection strategies have opened new ways for engineering durable resistance in crop plants.
Mouse Models of Innate Immunity
Irving C. Allen
Author : Irving C. Allen
Publisher : Humana
Page : 0 pages
File Size : 49,5 Mb
Release : 2016-08-27
Category : Medical
ISBN : 1493960369
Mouse Models of Innate Immunity by Irving C. Allen Pdf
The innate immune system represents a critical arm of the immune response by providing immediate and robust host defense; however, human studies of its function are often limited by ethical, logistical, and technical obstacles. In Mouse Models of Innate Immunity: Methods and Protocols, experts in the field explore the design and execution of experiments used to thoroughly evaluate critical elements associated with the host innate immune response. The volume opens with methods that are essential for collecting and assessing various primary cells that are highly relevant to innate immunity, and it continues with in vivo protocols commonly used to evaluate the innate immune response in the mouse, including mouse models of respiratory infection, gastrointestinal inflammation, fungal and parasitic diseases, sepsis, and HIV-1 infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Mouse Models of Innate Immunity: Methods and Protocols will serve the research community by providing expert advice and protocols that allow both experienced and novice investigators to successfully plan, implement, and assess disease processes associated with the innate immune response.
Antibody Fc:
Margaret Ackerman,Falk Nimmerjahn
Author : Margaret Ackerman,Falk Nimmerjahn
Publisher : Academic Press
Page : 358 pages
File Size : 45,6 Mb
Release : 2013-08-06
Category : Medical
ISBN : 9780123948182
Antibody Fc: by Margaret Ackerman,Falk Nimmerjahn Pdf
Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies Color illustrations enhance explanations of the immune system
Switching on Plant Innate Immunity Signaling Systems
P. Vidhyasekaran
Author : P. Vidhyasekaran
Publisher : Springer
Page : 358 pages
File Size : 47,6 Mb
Release : 2016-01-23
Category : Science
ISBN : 9783319261188
Switching on Plant Innate Immunity Signaling Systems by P. Vidhyasekaran Pdf
This book presents the ways and means to switch on plant immune signaling systems using PAMP-PIMP-PRR signaling complex for crop disease management. It also describes bioengineering approaches to develop transgenic plants expressing enhanced disease resistance using genes encoding PAMPs, PRRs and transcription factors and genes involved in generation of PIMPs/HAMPs. It also discusses recent commercial development of PAMP products to switch on plant innate immunity for crop disease management. These unique approaches have been described with more than 100 figures and illustrations and these would make this book attractive for researchers and students to buy this book.
Invertebrate Immunity
Kenneth Söderhäll
Author : Kenneth Söderhäll
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 44,6 Mb
Release : 2011-06-28
Category : Medical
ISBN : 9781441980595
Invertebrate Immunity by Kenneth Söderhäll Pdf
It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates
Concepts of Biology
Samantha Fowler,Rebecca Roush,James Wise
Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 55,5 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457
Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf
Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
Innate Immunity in Health and Disease
Shailendra K. Saxena,Hridayesh Prakash
Author : Shailendra K. Saxena,Hridayesh Prakash
Publisher : BoD – Books on Demand
Page : 416 pages
File Size : 43,6 Mb
Release : 2021-08-25
Category : Medical
ISBN : 9781838807658
Innate Immunity in Health and Disease by Shailendra K. Saxena,Hridayesh Prakash Pdf
The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
Innate Immune System of Skin and Oral Mucosa
Nava Dayan,Philip W. Wertz
Author : Nava Dayan,Philip W. Wertz
Publisher : John Wiley & Sons
Page : 372 pages
File Size : 49,9 Mb
Release : 2011-06-09
Category : Medical
ISBN : 9781118025321
Innate Immune System of Skin and Oral Mucosa by Nava Dayan,Philip W. Wertz Pdf
An in-depth look at cutting-edge research on the body's innate immune system Innate immunity is the body's first line of protection against potential microbial, viral, and environmental attacks, and the skin and oral mucosa are two of the most powerful barriers that which we rely on to stay well. The definitive book on the subject, Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products provides a comprehensive overview of these systems, including coverage of antimicrobial peptides and lipids and microbial challenges and stressors that can influence innate immunity. Designed to help experts and newcomers alike in fields like dermatology, oral pathology, cosmetics, personal care, and pharmaceuticals, the book is filled with suggestions to assist research and development. Looking at the many challenges facing the innate immune system, including the impact of topically applied skin products and medications, Innate Immune System of Skin and Oral Mucosa paves the way for next generation treatment avenues, preventative approaches, and drug development.
Toll-Like Receptors (TLRs) and Innate Immunity
Stefan Bauer,Gunther Hartmann
Author : Stefan Bauer,Gunther Hartmann
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 45,5 Mb
Release : 2007-12-11
Category : Medical
ISBN : 9783540721673
Toll-Like Receptors (TLRs) and Innate Immunity by Stefan Bauer,Gunther Hartmann Pdf
Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
Autophagy Regulation of Innate Immunity
Jun Cui
Author : Jun Cui
Publisher : Springer Nature
Page : 203 pages
File Size : 40,6 Mb
Release : 2019-11-14
Category : Medical
ISBN : 9789811506062
Autophagy Regulation of Innate Immunity by Jun Cui Pdf
This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine.