Focus On Bacterial Biofilms

Author : Theerthankar Das
Publisher : BoD – Books on Demand
Page : 393 pages
File Size : 50,5 Mb
Release : 2022-11-02
Category : Science
ISBN : 9781803557953

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Focus on Bacterial Biofilms by Theerthankar Das Pdf

Bacterial biofilms are colonies of bacterial cells embedded in their self-produced matrix composed of polysaccharides, DNA, and proteins. They protect bacterial cells against antibiotics, antibacterial agents, soaps and detergents, and shear stress. Some of the most common biofilm-associated infections in humans include urinary tract infections, infection of wounds and surgical sites, diabetic foot ulcers, dental caries (tooth decay) and gingivitis (gum inflammation), ventilator-associated infections, sinusitis, microbial keratitis, secondary infection related to Covid-19 and other viral infections, and so on. Bacterial resistance to common antibiotics (e.g., penicillin, gentamycin, erythromycin, ciprofloxacin, etc.) is driving us to a catastrophic failure of our health systems. Strategies to develop novel antibacterial agents and technology must be prioritized to combat and eradicate biofilms and their associated challenges. This book provides a comprehensive overview of biofilms with chapters on bacterial virulence factors, quorum sensing in bacteria, antimicrobial resistance in bacteria, strategies to develop new antibacterial agents, and much more.

Author : Sabu Thomas
Publisher : Cambridge Scholars Publishing
Page : 381 pages
File Size : 40,8 Mb
Release : 2020-01-10
Category : Science
ISBN : 9781527545175

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Emerging Concepts in Bacterial Biofilms by Sabu Thomas Pdf

The ability to form biofilms is a universal attribute of bacteria. Bacteria are able to grow on almost every surface, forming these architecturally complex communities. In biofilms, the cells grow in multicellular aggregates, encased in an extracellular matrix produced by the bacteria themselves. They impact humans in many ways, and can form in natural, medical and industrial settings. For example, the formation of biofilms on medical devices such as catheters or implants often results in difficult-to-treat chronic infections. This book focuses on emerging concepts in bacterial biofilm research, such as the different mechanisms of biofilm formation in Gram negative and Gram positive bacteria, and the burden of biofilm associated infections. It also highlights the various anti-biofilm strategies that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.

Author : Tony Romeo
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 46,8 Mb
Release : 2008-02-26
Category : Medical
ISBN : 9783540754183

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Bacterial Biofilms by Tony Romeo Pdf

Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Author : Mahmoud Ghannoum,Matthew Parsek,Marvin Whiteley,Pranab K. Mukherjee
Publisher : John Wiley & Sons
Page : 608 pages
File Size : 48,9 Mb
Release : 2015-10-01
Category : Science
ISBN : 9781683673330

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Microbial Biofilms by Mahmoud Ghannoum,Matthew Parsek,Marvin Whiteley,Pranab K. Mukherjee Pdf

An examination of the research and translational application to prevent and treat biofilm-associated diseases In the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense. Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically, Microbial Biofilms provides state-of-the-art research in the field of bacterial and fungal biofilms detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms future areas of research and their translational and clinical applications Microbial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.

Author : Hideyuki Kanematsu,Dana M. Barry
Publisher : Springer Nature
Page : 240 pages
File Size : 47,7 Mb
Release : 2020-01-25
Category : Science
ISBN : 9789811522406

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Formation and Control of Biofilm in Various Environments by Hideyuki Kanematsu,Dana M. Barry Pdf

This book provides excellent techniques for detecting and evaluating biofilms: sticky films on materials that are formed by bacterial activity and produce a range of industrial and medical problems such as corrosion, sanitary problems, and infections. Accordingly, it is essential to control biofilms and to establish appropriate countermeasures, from both industrial and medical viewpoints. This book offers valuable, detailed information on these countermeasures. It also discusses the fundamentals of biofilms, relates various substrates to biofilms, and presents a variety of biofilm reactors. However, the most important feature of this book (unlike others on the market) is its clear focus on addressing the practical aspects from an engineering viewpoint. Therefore, it offers an excellent practical guide for engineers and researchers in various fields, and can also be used as a great academic textbook.

Author : Sabu Thomas
Publisher : Cambridge Scholars Publishing
Page : 381 pages
File Size : 46,8 Mb
Release : 2020
Category : Electronic
ISBN : 1527542610

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Emerging Concepts in Bacterial Biofilms by Sabu Thomas Pdf

The ability to form biofilms is a universal attribute of bacteria. Bacteria are able to grow on almost every surface, forming these architecturally complex communities. In biofilms, the cells grow in multicellular aggregates, encased in an extracellular matrix produced by the bacteria themselves. They impact humans in many ways, and can form in natural, medical and industrial settings. For example, the formation of biofilms on medical devices such as catheters or implants often results in difficult-to-treat chronic infections. This book focuses on emerging concepts in bacterial biofilm research, such as the different mechanisms of biofilm formation in Gram negative and Gram positive bacteria, and the burden of biofilm associated infections. It also highlights the various anti-biofilm strategies that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.

Author : Sadik Dincer,Melis Sümengen Özdenefe,Afet Arkut
Publisher : BoD – Books on Demand
Page : 362 pages
File Size : 52,7 Mb
Release : 2020-10-07
Category : Science
ISBN : 9781789858990

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Bacterial Biofilms by Sadik Dincer,Melis Sümengen Özdenefe,Afet Arkut Pdf

This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.

Author : Thomas Bjarnsholt,Peter Østrup Jensen,Claus Moser,Niels Høiby
Publisher : Springer
Page : 0 pages
File Size : 40,9 Mb
Release : 2014-10-11
Category : Science
ISBN : 1489982280

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Biofilm Infections by Thomas Bjarnsholt,Peter Østrup Jensen,Claus Moser,Niels Høiby Pdf

This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Author : Reham Wasfi,Samira Mohamed Hamed,Ashraf Zarkan
Publisher : Frontiers Media SA
Page : 139 pages
File Size : 40,6 Mb
Release : 2023-08-25
Category : Science
ISBN : 9782832532560

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Emerging Strategies in Combatting and Managing Bacterial Biofilms by Reham Wasfi,Samira Mohamed Hamed,Ashraf Zarkan Pdf

Biofilm formation is a survival strategy for many microorganisms. Within biofilms, microorganisms live in multicellular communities enclosed in a protective matrix that enables them to survive harsh conditions and resist conventional treatments. The ability of biofilm-forming microorganisms to inhabit different biotic and abiotic surfaces facilitates their widespread existence in different environments including health care facilities, water systems, ships, and even living hosts. Hence, this microbial phenotype became a major concern in various sectors including public health, medicine, and industry. The challenge imparted by the detrimental effects of biofilms has sparked the interest of many researchers in tackling this problem. Biofilms are not simply a collection of microorganisms but can be considered as new materials. Current research efforts have focused on understanding the mechanisms of biofilm formation and factors affecting their structures, as well as innovative approaches for combating biofilms and achieving rapid biofilm detection. Prevention and proper management of biofilms necessitates a deep understanding of the mechanisms of their formation and the factors affecting their development. It is established that biofilm formation undergoes multiple stages from initial surface adhesion to maturation and dispersion. However, how bacteria trigger, regulate and modulate each stage is not yet well understood. Additionally, early detection of biofilms facilitates early intervention and, consequently, reduction in the economic loss and clinical burden. However, detection of cells within biofilms is particularly challenging and innovative sensing, tracking and diagnostic technologies are needed. Clinically, biofilm formation is a key aspect of antibiotic resistance. Biofilms are not merely protective barriers against antibiotics and the host immune system, but also harbour non-growing “persister” bacteria that survive antibiotics by virtue of their dormancy. It is established that both persisters and biofilms are implicated in chronic infections. However, the triggering factors of their formation are not fully understood. Viable but non culturable (VBNC) cells is another group of non-growing bacteria that can inhabit biofilms and remain dormant for extended periods. The trigger for their formation and revival as well as clinical relevance is unclear.

Author : Hilary M. Lappin-Scott,J. William Costerton
Publisher : Cambridge University Press
Page : 332 pages
File Size : 47,9 Mb
Release : 2003-09-18
Category : Medical
ISBN : 052154212X

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Microbial Biofilms by Hilary M. Lappin-Scott,J. William Costerton Pdf

Biochemistry and ecology of biofilms from industrial, medical and other viewpoints.

Author : Emmy Klieneberger-Nobel
Publisher : Unknown
Page : 164 pages
File Size : 51,6 Mb
Release : 1965
Category : Bacteriology
ISBN : UOM:39015022094026

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Focus on Bacteria by Emmy Klieneberger-Nobel Pdf

Author : S. Eick
Publisher : Karger Medical and Scientific Publishers
Page : 247 pages
File Size : 45,5 Mb
Release : 2020-12-21
Category : Medical
ISBN : 9783318068528

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Oral Biofilms by S. Eick Pdf

Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.

Author : Mukesh Kumar Yadav,Bhim Pratap Singh
Publisher : Elsevier
Page : 324 pages
File Size : 43,9 Mb
Release : 2019-10-10
Category : Technology & Engineering
ISBN : 9780444642806

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New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms by Mukesh Kumar Yadav,Bhim Pratap Singh Pdf

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms is divided into three sections: microbial adhesion/biofilms in medical settings, microbial adhesion/biofilms in agriculture, and microbial adhesion/biofilm in the environment and industry. Chapters cover adhesion and biofilm formation by pathogenic microbes on tissue and on indwelling medical devices, including sections on human infections, microbial communication during biofilm mode of growth, host defense and antimicrobial resistance, and more. Other sections cover the biofilms of agriculturally important and environmental friendly microbes, including biofilm formation on plants, in soil, and in aquatic environments. Finally, the latest scientific research on microbial adhesion and biofilm formation in the environment and in industry is covered. Provides an overview on the growth, structure, cell-to-cell interactions, and control/dispersal of bacterial and fungal of in vitro and in vivo biofilms Presents an overview on the microbial adhesion, biofilm formation and structures of single-species and multi-species biofilms on human tissues/medical devices, agriculture, environment and chemical industries Includes chapters on microbial biofilms of pathogenic microbes on human tissues and in medical indwelling devices Covers factors affecting microbial biofilm, adhesion and formation

Author : Anonim
Publisher : Academic Press
Page : 759 pages
File Size : 51,5 Mb
Release : 1999-10-27
Category : Science
ISBN : 9780080548722

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Biofilms by Anonim Pdf

Volume 310 of Methods in Enzymology is the first volume devoted solely to biofilm research methods. It provides a contemporary source book for virtually any kind of experimental approach involving biofilms. It includes bioengineering, molecular, genetic, microscopic, chemical, continuous culture, and physical methods. This volume will serve as a starting point for future developments.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Author : Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle
Publisher : Academic Press
Page : 394 pages
File Size : 49,8 Mb
Release : 2014-01-30
Category : Science
ISBN : 9780123977519

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Biofilms in Infection Prevention and Control by Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle Pdf

Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. Provides specific procedures for controlling and preventing infection Includes case studies of HCAI, and identifies appropriate treatments Presents national government standards for infection prevention and control Includes extensive references and links to websites for further information