Folic Acid Metabolism In Health And Disease

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Folic Acid Metabolism in Health and Disease

Mary Frances Picciano,E. L. Robert Stokstad,Jesse F. Gregory
Folic Acid Metabolism in Health and Disease Book PDF

Author : Mary Frances Picciano,E. L. Robert Stokstad,Jesse F. Gregory
Publisher : Unknown
Page : 320 pages
File Size : 44,8 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015018508088

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Folic Acid Metabolism in Health and Disease by Mary Frances Picciano,E. L. Robert Stokstad,Jesse F. Gregory Pdf

Abstract: This publication provides a background on the biochemistry and physiology of folic acid and discusses recent developments in analytical methodology and the clinical aspects of folic acid nutrition. Topics include: an historical account of the advances in the biochemistry and function of folic acid; the regulation of folic acid metabolism and the use of antagonists to study folate metabolism and transport by cells; the intestinal absorption of dietary folates; microbiological growth techniques; ani mal bioassays for measuring bioavailability of food folates; clinical aspects of dietary, physiological, and deficiency concerns; and the evaluation of folate nutritional status in infants, adolescents, adults, and other population groups.

Folate in Health and Disease

Lynn B. Bailey
Folate in Health and Disease Book PDF

Author : Lynn B. Bailey
Publisher : CRC Press
Page : 602 pages
File Size : 52,5 Mb
Release : 2009-11-24
Category : Medical
ISBN : 9781420071252

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Folate in Health and Disease by Lynn B. Bailey Pdf

During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease. The second edition of the book uniquely bridges the gap between basic science and public health/clinical medicine.Presents Groundbreaking

Folate and Human Development

Edward J. Massaro,John M. Rogers
Folate and Human Development Book PDF

Author : Edward J. Massaro,John M. Rogers
Publisher : Springer Science & Business Media
Page : 365 pages
File Size : 42,7 Mb
Release : 2002-03-10
Category : Medical
ISBN : 9781592591640

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Folate and Human Development by Edward J. Massaro,John M. Rogers Pdf

Folic acid not only helps to prevent a variety of serious neural-tube birth defects-among them anencephaly and spina bifida-but is also an important factor in general human health. In Folate and Human Development, an authoritative panel of basic and clinical researchers critically reviews the latest findings on the role of folate in human development, health, and disease. Specific areas addressed include folate metabolism in zinc or copper deficiencies, choline and folate in development, animal models of folate-related birth defects, developmental toxicants potentially acting via folate perturbation, and folate's role in vascular disease in women. There are also cutting-edge discussions of genes and neural tube development, folate receptor polymorphism and the risk for neural defects, abnormal DNA synthesis and methylation with folate/methyl insufficiency, and folic acid and homocysteine as risk factors for neural-tube defects. Comprehensive and up-to-date, Folate and Human Development critically evaluates our current understanding of the role of folates in human health and disease, offering biomedical and clinical researchers a deeper understanding of the folate and nutrient basis of neural-tube defects.

Folic Acid

Stephen M. Lee
Folic Acid Book PDF

Author : Stephen M. Lee
Publisher : Unknown
Page : 180 pages
File Size : 53,9 Mb
Release : 2017
Category : Medical
ISBN : 1536118354

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Folic Acid by Stephen M. Lee Pdf

This book reviews and discusses the most relevant epidemiological aspects of OFCs and its prevention. It evaluates the role of folate and other factors in preventing OFC by analysing the health and socio-demographic data collected from a population sample. Individuals that are deficient in folates are suggested to have increase vulnerability to disease, including neurological conditions. Folates are involved in the metabolism of homocysteine which is a sulfur containing non-protein amino acid. This book will also highlight the recent advances made in understanding the effect of dietary folic acid over supplementation on neurological function. Patients with low levels of folic acid and other B vitamins, metabolism disorders, and renal failure have frequently high homocysteine levels that have been especially associated with cardiovascular and bone disease. This book reviews and analyzes the most important results about the effects of folic acid supplementation on clinical targets and it focuses on the effects of folic acid therapy on clinical outcomes of chronic renal failure patients with high homocysteine levels.

Functional Food

María Chávarri Hueda
Functional Food Book PDF

Author : María Chávarri Hueda
Publisher : BoD – Books on Demand
Page : 320 pages
File Size : 49,7 Mb
Release : 2017-08-02
Category : Science
ISBN : 9789535134398

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Functional Food by María Chávarri Hueda Pdf

In recent years, the concern of society about how food influences the health status of people has increased. Consumers are increasingly aware that food can prevent the development of certain diseases, so in recent years, the food industry is developing new, healthier products taking into account aspects such as trans fats, lower caloric intake, less salt, etc. However, there are bioactive compounds that can improve the beneficial effect of these foods and go beyond the nutritional value. This book provides information on impact of bioactive ingredients (vitamins, antioxidants, compounds of the pulses, etc.) on nutrition through food, how functional foods can prevent disease, and tools to evaluate the effects of bioactive ingredients, functional foods, and diet.

Folic Acid

William L. Bruneau
Folic Acid Book PDF

Author : William L. Bruneau
Publisher : WB Publisher
Page : 128 pages
File Size : 45,7 Mb
Release : 2006-01-01
Category : Electronic
ISBN : 0974879916

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Folic Acid by William L. Bruneau Pdf

Folic Acid is clearly written in language that is easily understood by the average reader. While solidly based on peer-reviewed research, this book is a very readable, basic primer for anyone who wants the benefits of improved health and longevity. It is our humble opinion that even health professionals could benefit greatly from referring to this absolutely up-to-date summation of all relevant published research through November, 2006. Folic acid is the popular synthetic form, the term folate referes to all members of this vitamin family. Folates are best known for theirimportance in avoiding birth defects, but research in the last few years has established that they are absolutely essential for everyone's health and well-being. They are now known to be crucial for the proper functioning of your cells and your genes.Various scientific studies claim that anywhere from 10% to 67% of us (men, women, and children) are deficient in folate and at risk for many deficiency diseases. Young women of child-bearing age have the greatest need and paradoxically tend to have low levels of folate - even after food fortification!Folic Acid (the book) contains everything you need to know about this crucial vitamin. Fully up-to-date, it is based on the latest scientific research. This book describes what folates are, what they do to your body, and how and why they are crucial for your health and longevity. This book describes folate's many health benefits, and an impressive list of diseases and conditions caused by a folate deficiency in your body. How much to take for optimum health is described. Current research questions the adequacy of the current Recommended Daily Allowances. A central theme of this book is to help determine what is adequate - which varies significantly and is probably different for any given reader. Homocysteine is also explained in this book - what it is and why abnormal levels have become such a concern to health professionals. While folic acid is the largest single determinant of your homocysteine level, this book clearly describes the other known factors that affect your level of homocysteine. The relevance of recently discovered mutations in crucial genes that govern the folate metabolism are also covered.Throughout this book are "scorecards" that visually summarize the known evidence for such topics as "Who is Deficient?" or "What is Average?"

Inborn Errors of Metabolism

Brendan Lee,Fernando Scaglia
Inborn Errors of Metabolism Book PDF

Author : Brendan Lee,Fernando Scaglia
Publisher : Oxford Monographs on Medical G
Page : 393 pages
File Size : 49,9 Mb
Release : 2014-10-13
Category : Medical
ISBN : 9780199797585

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Inborn Errors of Metabolism by Brendan Lee,Fernando Scaglia Pdf

This volume is an expansion on the known treatment model of IEMs, one that establishes an innovative pathway approach and provides a new authority on this family of disease. Alongside the standard cadre of molecular and clinical underpinnings, this book includes coverage of newborn screening and an overarching treatment of IEMs as complex diseases.

Nutrient Metabolism

Martin Kohlmeier
Nutrient Metabolism Book PDF

Author : Martin Kohlmeier
Publisher : Elsevier
Page : 841 pages
File Size : 40,5 Mb
Release : 2003-10-01
Category : Medical
ISBN : 9780080537894

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Nutrient Metabolism by Martin Kohlmeier Pdf

Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

Medical Biochemistry

Miriam D. Rosenthal,Robert H. Glew
Medical Biochemistry Book PDF

Author : Miriam D. Rosenthal,Robert H. Glew
Publisher : John Wiley & Sons
Page : 455 pages
File Size : 46,8 Mb
Release : 2011-09-20
Category : Science
ISBN : 9781118210291

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Medical Biochemistry by Miriam D. Rosenthal,Robert H. Glew Pdf

Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.

Homocysteine in Health and Disease

Ralph Carmel,Donald W. Jacobsen
Homocysteine in Health and Disease Book PDF

Author : Ralph Carmel,Donald W. Jacobsen
Publisher : Cambridge University Press
Page : 558 pages
File Size : 45,8 Mb
Release : 2001-07-19
Category : Medical
ISBN : 0521653193

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Homocysteine in Health and Disease by Ralph Carmel,Donald W. Jacobsen Pdf

This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.

Interrelations between Essential Metal Ions and Human Diseases

Astrid Sigel,Helmut Sigel,Roland K.O. Sigel
Interrelations between Essential Metal Ions and Human Diseases Book PDF

Author : Astrid Sigel,Helmut Sigel,Roland K.O. Sigel
Publisher : Springer Science & Business Media
Page : 603 pages
File Size : 41,5 Mb
Release : 2014-01-27
Category : Science
ISBN : 9789400775008

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Interrelations between Essential Metal Ions and Human Diseases by Astrid Sigel,Helmut Sigel,Roland K.O. Sigel Pdf

MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.

Handbook of Drug-Nutrient Interactions

Joseph I. Boullata,Vincent T. Armenti
Handbook of Drug Nutrient Interactions Book PDF

Author : Joseph I. Boullata,Vincent T. Armenti
Publisher : Springer Science & Business Media
Page : 824 pages
File Size : 41,5 Mb
Release : 2010-03-17
Category : Science
ISBN : 9781603273626

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Handbook of Drug-Nutrient Interactions by Joseph I. Boullata,Vincent T. Armenti Pdf

Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.

Diet and Health

National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Diet and Health
Diet and Health Book PDF

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Diet and Health
Publisher : National Academies Press
Page : 765 pages
File Size : 54,5 Mb
Release : 1989-01-01
Category : Medical
ISBN : 9780309039949

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Diet and Health by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Diet and Health Pdf

Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Water Soluble Vitamins

Olaf Stanger
Water Soluble Vitamins Book PDF

Author : Olaf Stanger
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 42,5 Mb
Release : 2011-11-27
Category : Medical
ISBN : 9789400721999

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Water Soluble Vitamins by Olaf Stanger Pdf

The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, derived from “vital-amines”, indicates their elementary metabolic key functions in human metabolism. Vitamins are truly families of compounds, which include precursors and various free and bound forms, all with individual roles in metabolism and function. A more recent approach therefore searches for the components, the understanding of their roles in physiology and pathology as well as looking for novel pharmacological applications. When used properly, vitamins are, indeed, “magical” substances. Due to their efficacy, they should therefore be regarded as drugs with effects and side effects to be weighted against each other. Today, it is not the previously fatal deficiency-associated diseases that are in the focus of interest, but rather the relation of suboptimal vitamin bioavailability to chronic disease. This is complicated by genetic susceptibility, lifestyle, and the presence or absence of health-compromising habits, such as smoking. In turn, the development and application of new and more sensitive and specific assays further enable us to look more closely into the many functions of vitamins. Water soluble vitamins are complex molecular structures and even today, many areas in vitamin biochemistry are not yet fully understood. Novel effects and functions of vitamins remain and continue to be discovered. This book presents most recent research results and fascinating new knowledge on the role and effects of the water soluble vitamins in man. Some of the most distinguished chemists, biochemists, biologists and clinicians have contributed valuable chapters sharing unexpected novel insights into the biochemistry, (epi)genetics, metabolism, and function of water soluble vitamins, with their potential for clinical applications. Thus, physicians, clinicians, scientists, researchers, epidemiologists. nutritional specialists and health professionals alike will find stimulating and fascinating new insight in the many roles that water soluble vitamins play in human health and disease.

Nutritional Biochemistry of the Vitamins

David A. Bender
Nutritional Biochemistry of the Vitamins Book PDF

Author : David A. Bender
Publisher : Cambridge University Press
Page : 514 pages
File Size : 53,6 Mb
Release : 2003-09-18
Category : Science
ISBN : 9781139437738

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Nutritional Biochemistry of the Vitamins by David A. Bender Pdf

An authoritative and comprehensive review of our current knowledge of the vitamins, their metabolic functions and the scientific basis for setting recommended intakes for the prevention of deficiency and promotion of optimum health. This publication will be a valuable reference for students and specialists alike in the field of nutritional biochemistry.