Forensic Dna Typing

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DNA Technology in Forensic Science

National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on DNA Technology in Forensic Science
DNA Technology in Forensic Science Book PDF

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on DNA Technology in Forensic Science
Publisher : National Academies Press
Page : 199 pages
File Size : 44,7 Mb
Release : 1992-02-01
Category : Science
ISBN : 9780309045872

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DNA Technology in Forensic Science by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on DNA Technology in Forensic Science Pdf

Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.

Fundamentals of Forensic DNA Typing

John M. Butler
Fundamentals of Forensic DNA Typing Book PDF

Author : John M. Butler
Publisher : Academic Press
Page : 519 pages
File Size : 44,8 Mb
Release : 2009-09-30
Category : Law
ISBN : 9780080961767

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Fundamentals of Forensic DNA Typing by John M. Butler Pdf

Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Advanced Topics in Forensic DNA Typing: Interpretation

John M. Butler
Advanced Topics in Forensic DNA Typing Interpretation Book PDF

Author : John M. Butler
Publisher : Academic Press
Page : 608 pages
File Size : 49,9 Mb
Release : 2014-07-28
Category : Social Science
ISBN : 9780124058545

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Advanced Topics in Forensic DNA Typing: Interpretation by John M. Butler Pdf

Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence Worked mixture examples illustrate the impact of different statistical approaches for reporting results Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011

Forensic DNA Typing: Principles, Applications and Advancements

Pankaj Shrivastava,Hirak Ranjan Dash,Jose A. Lorente,Jahangir Imam
Forensic DNA Typing Principles Applications and Advancements Book PDF

Author : Pankaj Shrivastava,Hirak Ranjan Dash,Jose A. Lorente,Jahangir Imam
Publisher : Springer Nature
Page : 673 pages
File Size : 54,9 Mb
Release : 2020-12-11
Category : Science
ISBN : 9789811566554

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Forensic DNA Typing: Principles, Applications and Advancements by Pankaj Shrivastava,Hirak Ranjan Dash,Jose A. Lorente,Jahangir Imam Pdf

The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis. Module 3 emphasizes various technologies that are based on SNPs, STRs namely Y-STR, X-STR, mitochondrial DNA profiling in forensic science. Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping. Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level.

Forensic DNA Typing

John M. Butler
Forensic DNA Typing Book PDF

Author : John M. Butler
Publisher : Elsevier
Page : 688 pages
File Size : 40,5 Mb
Release : 2005-02-08
Category : Law
ISBN : 0080470610

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Forensic DNA Typing by John M. Butler Pdf

Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable. This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. *The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome *Chapters cover the topic from introductory level right up to "cutting edge" research *High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases *NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions

The Evaluation of Forensic DNA Evidence

National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on DNA Forensic Science: An Update
The Evaluation of Forensic DNA Evidence Book PDF

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on DNA Forensic Science: An Update
Publisher : National Academies Press
Page : 271 pages
File Size : 44,6 Mb
Release : 1997-01-12
Category : Science
ISBN : 9780309121941

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The Evaluation of Forensic DNA Evidence by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on DNA Forensic Science: An Update Pdf

In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

Nonhuman DNA Typing

Heather Miller Coyle
Nonhuman DNA Typing Book PDF

Author : Heather Miller Coyle
Publisher : CRC Press
Page : 193 pages
File Size : 45,9 Mb
Release : 2007-08-29
Category : Law
ISBN : 9781040079881

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Nonhuman DNA Typing by Heather Miller Coyle Pdf

The association of a suspect with the victim or crime scene through DNA evidence is one of the most powerful statements of complicity in a crime imaginable. No category of evidence has ever had the complete capacity to convict or exonerate an accused so absolutely in the eyes of the public. With the discriminatory powers of DNA and the variety of D

Forensic DNA Biology

Kelly M. Elkins
Forensic DNA Biology Book PDF

Author : Kelly M. Elkins
Publisher : Academic Press
Page : 226 pages
File Size : 40,6 Mb
Release : 2012-09-11
Category : Law
ISBN : 9780123945853

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Forensic DNA Biology by Kelly M. Elkins Pdf

A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.

Forensic Analysis of Biological Evidence

J. Thomas McClintock
Forensic Analysis of Biological Evidence Book PDF

Author : J. Thomas McClintock
Publisher : CRC Press
Page : 176 pages
File Size : 54,5 Mb
Release : 2017-08-02
Category : Law
ISBN : 9781466504585

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Forensic Analysis of Biological Evidence by J. Thomas McClintock Pdf

A powerful tool in the identification of individuals, DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories, Forensic Analysis of Biological Evidence: A Laboratory

Forensic DNA Typing Protocols

Angel Carracedo
Forensic DNA Typing Protocols Book PDF

Author : Angel Carracedo
Publisher : Springer Science & Business Media
Page : 282 pages
File Size : 47,5 Mb
Release : 2008-02-02
Category : Medical
ISBN : 9781592598670

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Forensic DNA Typing Protocols by Angel Carracedo Pdf

A state-of-the-art collection of readily reproducible laboratory methods for DNA identity analysis, including Y chromosome haplotyping, mtDNA, and SNP typing. The book offers well-tested protocols for DNA quantification using real-time PCR on forensic samples and for the determination of the number of amelogenine gene copies. For forensic geneticists, there are readily reproducible methods for species identification, ancient DNA, and pharmacogenetics. Additional chapters address new applications in the forensic genetics lab, such a species identification or typing of CYP polymorphisms for the analysis of adverse to drugs.

Forensic DNA Evidence Interpretation, Second Edition

John S. Buckleton,Jo-Anne Bright,Duncan Taylor
Forensic DNA Evidence Interpretation Second Edition Book PDF

Author : John S. Buckleton,Jo-Anne Bright,Duncan Taylor
Publisher : CRC Press
Page : 496 pages
File Size : 52,5 Mb
Release : 2016-04-21
Category : Law
ISBN : 9781482258929

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Forensic DNA Evidence Interpretation, Second Edition by John S. Buckleton,Jo-Anne Bright,Duncan Taylor Pdf

Now in its second edition, Forensic DNA Evidence Interpretation is the most comprehensive resource for DNA casework available today. Written by leaders in the fields of biology and statistics, including a contribution from Peter Gill, the father of DNA analysis, the book emphasizes the interpretation of test results and provides the necessary formulae in an easily accessible manner. This latest edition is fully updated and includes current and emerging techniques in this fast-moving field. The book begins by reviewing all pertinent biology, and then provides information on every aspect of DNA analysis. This includes modern interpretation methods and contemporary population genetic models available for estimating DNA frequencies or likelihood ratios. Following a chapter on procedures for validating databases, the text presents overviews and performance assessments of both modern sampling uncertainty methods and current paternity testing techniques, including new guidelines on paternity testing in alignment with the International Society for Forensic Genetics. Later chapters discuss the latest methods for mixture analysis, LCN (ultra trace) analysis and non-autosomal (mito, X, and Y) DNA analysis. The text concludes with an overview of procedures for disaster victim identification and information on DNA intelligence databases. Highlights of the second edition include: New information about PCR processes, heterozygote balance and back and forward stuttering New information on the interpretation of low template DNA, drop models and continuous models Additional coverage of lineage marker subpopulation effects, mixtures and combinations with autosomal markers This authoritative book provides a link among the biological, forensic, and interpretative domains of the DNA profiling field. It continues to serve as an invaluable resource that allows forensic scientists, technicians, molecular biologists and attorneys to use forensic DNA evidence to its greatest potential.

Wildlife DNA Analysis

Adrian Linacre,Shanan Tobe
Wildlife DNA Analysis Book PDF

Author : Adrian Linacre,Shanan Tobe
Publisher : John Wiley & Sons
Page : 360 pages
File Size : 41,9 Mb
Release : 2013-03-27
Category : Medical
ISBN : 9781118496527

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Wildlife DNA Analysis by Adrian Linacre,Shanan Tobe Pdf

Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements.

Forensic DNA Analysis

J. Thomas McClintock
Forensic DNA Analysis Book PDF

Author : J. Thomas McClintock
Publisher : CRC Press
Page : 178 pages
File Size : 49,6 Mb
Release : 2008-02-19
Category : Law
ISBN : 9781420063301

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Forensic DNA Analysis by J. Thomas McClintock Pdf

In its short but active history, the use of DNA typing has revolutionized criminal investigations. It is almost inconceivable to bring a case to trial without positive identification through what is now our most accurate means. Proficiency with the methodology, principles, and interpretation of DNA evidence is crucial for today‘s criminalist.

A Guide to Forensic DNA Profiling

Scott Bader
A Guide to Forensic DNA Profiling Book PDF

Author : Scott Bader
Publisher : John Wiley & Sons
Page : 453 pages
File Size : 48,5 Mb
Release : 2016-03-21
Category : Law
ISBN : 9781118751527

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A Guide to Forensic DNA Profiling by Scott Bader Pdf

The increasingly arcane world of DNA profiling demands that those needing to understand at least some of it must find a source of reliable and understandable information. Combining material from the successful Wiley Encyclopedia of Forensic Science with newly commissioned and updated material, the Editors have used their own extensive experience in criminal casework across the world to compile an informative guide that will provide knowledge and thought-provoking articles of interest to anyone involved or interested in the use of DNA in the forensic context. Following extensive introductory chapters covering forensic DNA profiling and forensic genetics, this comprehensive volume presents a substantial breadth of material covering: Fundamental material – including sources of DNA, validation, and accreditation Analysis and interpretation – including, extraction, quantification, amplification and interpretation of electropherograms (epgs) Evaluation – including mixtures, low template, and transfer Applications – databases, paternity and kinship, mitochondrial-DNA, wildlife DNA, single-nucleotide polymorphism, phenotyping and familial searching Court - report writing, discovery, cross examination, and current controversies With contributions from leading experts across the whole gamut of forensic science, this volume is intended to be authoritative but not authoritarian, informative but comprehensible, and comprehensive but concise. It will prove to be a valuable addition, and useful resource, for scientists, lawyers, teachers, criminologists, and judges.

Forensic DNA Applications

Dragan Primorac,Moses Schanfield
Forensic DNA Applications Book PDF

Author : Dragan Primorac,Moses Schanfield
Publisher : CRC Press
Page : 652 pages
File Size : 53,6 Mb
Release : 2014-01-29
Category : Law
ISBN : 9781466580220

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Forensic DNA Applications by Dragan Primorac,Moses Schanfield Pdf

Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.