Fundamentals Of Antimicrobial Pharmacokinetics And Pharmacodynamics

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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Alexander A. Vinks,Hartmut Derendorf,Johan W. Mouton
Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics Book PDF

Author : Alexander A. Vinks,Hartmut Derendorf,Johan W. Mouton
Publisher : Springer Science & Business Media
Page : 466 pages
File Size : 47,5 Mb
Release : 2013-11-23
Category : Medical
ISBN : 9780387756134

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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics by Alexander A. Vinks,Hartmut Derendorf,Johan W. Mouton Pdf

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Essentials of Antimicrobial Pharmacology

Paul H. Axelsen
Essentials of Antimicrobial Pharmacology Book PDF

Author : Paul H. Axelsen
Publisher : Springer Science & Business Media
Page : 127 pages
File Size : 55,9 Mb
Release : 2001-09-15
Category : Medical
ISBN : 9781592591220

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Essentials of Antimicrobial Pharmacology by Paul H. Axelsen Pdf

Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Charles H. Nightingale,Paul G. Ambrose,George L. Drusano,Takeo Murakawa
Antimicrobial Pharmacodynamics in Theory and Clinical Practice Book PDF

Author : Charles H. Nightingale,Paul G. Ambrose,George L. Drusano,Takeo Murakawa
Publisher : CRC Press
Page : 536 pages
File Size : 44,6 Mb
Release : 2007-06-15
Category : Medical
ISBN : 9781420017137

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Antimicrobial Pharmacodynamics in Theory and Clinical Practice by Charles H. Nightingale,Paul G. Ambrose,George L. Drusano,Takeo Murakawa Pdf

Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging

Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Nightingale,Mur
Antimicrobial Pharmacodynamics in Theory and Clinical Practice Book PDF

Author : Nightingale,Mur
Publisher : CRC Press
Page : 427 pages
File Size : 40,6 Mb
Release : 2001-09-25
Category : Medical
ISBN : 9780824741822

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Antimicrobial Pharmacodynamics in Theory and Clinical Practice by Nightingale,Mur Pdf

This up-to-the-minute reference explores the pharmacodynamics of antimicrobials as well as the absorption, distribution, metabolism, and elimination of the major classes of antimicrobials-covering new agents such as ketolide antibiotics and highlighting the pharmacodynamic relationship between drug concentration and antimicrobial activity, as well as the relationship of pharmacodynamics to bacterial resistance. Contains specific examples and practical applications for the design of effective dosing regimens! Written by recognized experts in the field, Antimicrobial Pharmacodynamics in Theory and Clinical Practice describes the pharmacodynamic properties of all major classes of antibiotics parameters for microbiological activity of antimicrobial agents such as minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) serum/tissue protein binding and penetration rates differences between in vivo and in vitro postantibiotic effects (PAE) and more! With nearly 1000 references, tables, drawings, and illustrations, Antimicrobial Pharmacodynamics in Theory and Clinical Practice is a state-of-the-art reference for infectious disease specialists, pulmonologists, pharmacists, pharmacologists, microbiologists, biological chemists, epidemiologists, internists, and students in these disciplines.

The Pharmacist's Guide to Antimicrobial Therapy and Stewardship

Sarah M. Wieczorkiewicz,Carrie A. Sincak
The Pharmacist s Guide to Antimicrobial Therapy and Stewardship Book PDF

Author : Sarah M. Wieczorkiewicz,Carrie A. Sincak
Publisher : Unknown
Page : 0 pages
File Size : 52,8 Mb
Release : 2016
Category : Anti-infective agents
ISBN : 1585285196

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The Pharmacist's Guide to Antimicrobial Therapy and Stewardship by Sarah M. Wieczorkiewicz,Carrie A. Sincak Pdf

When a patient comes in with a suspected infectious disease, knowledge is power. Now this knowledge is simplified, comprehensive and easy to find. The Pharmacist's Guide to Antimicrobial Therapy and Stewardship puts all the necessary information in one place, including: Evaluating potentially infected patients Identifying the infection's suspected source and related organisms Comparing the range of anti-infectives Knowing the factors that impact treatment Developing an antimicrobial stewardship program A step-wise approach walks logically from overall key concepts to disease- and drug-specific information. Disease states are summarized for easy reference. Tables make it easy to evaluate recommended treatment options. In infectious disease management, when answers are seldom black and white, this guide helps pharmacists make confident decisions.

Antibiotic Pharmacodynamics

John C. Rotschafer,David R. Andes,Keith A. Rodvold
Antibiotic Pharmacodynamics Book PDF

Author : John C. Rotschafer,David R. Andes,Keith A. Rodvold
Publisher : Humana
Page : 0 pages
File Size : 42,9 Mb
Release : 2016-03-30
Category : Medical
ISBN : 1493933213

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Antibiotic Pharmacodynamics by John C. Rotschafer,David R. Andes,Keith A. Rodvold Pdf

This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation. The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. As part of the Methods in Pharmacology and Toxicology series, chapters include detailed insight and practical information for the lab. Comprehensive and cutting-edge, Antibiotic Pharmacodynamics serves as an ideal reference for scientists investigating advances in antibiotic pharmacodynamics now finding their way into the antibiotic development process used for licensing new antibiotics.

Fundamentals of Anaesthesia

Colin Pinnock,Ted Lin,Robert Jones,Tim Smith
Fundamentals of Anaesthesia Book PDF

Author : Colin Pinnock,Ted Lin,Robert Jones,Tim Smith
Publisher : Cambridge University Press
Page : 990 pages
File Size : 42,8 Mb
Release : 2002-12
Category : Medical
ISBN : 052169079X

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Fundamentals of Anaesthesia by Colin Pinnock,Ted Lin,Robert Jones,Tim Smith Pdf

The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Oxford Textbook of Fundamentals of Surgery

William E. G. Thomas,William Ernest Ghinn Thomas,Malcolm W. R. Reed,Michael G. Wyatt
Oxford Textbook of Fundamentals of Surgery Book PDF

Author : William E. G. Thomas,William Ernest Ghinn Thomas,Malcolm W. R. Reed,Michael G. Wyatt
Publisher : Oxford University Press
Page : 849 pages
File Size : 46,5 Mb
Release : 2016-07-28
Category : Medical
ISBN : 9780199665549

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Oxford Textbook of Fundamentals of Surgery by William E. G. Thomas,William Ernest Ghinn Thomas,Malcolm W. R. Reed,Michael G. Wyatt Pdf

A definitive, accessible, and reliable resource which provides a solid foundation of the knowledge and basic science needed to hone all of the core surgical skills used in surgical settings. Presented in a clear and accessible way it addresses the cross-specialty aspects of surgery applicable to all trainees.

Kucers' The Use of Antibiotics

M. Lindsay Grayson,Sara E. Cosgrove,Suzanne Crowe,William Hope,James S. McCarthy,John Mills,Johan W. Mouton,David L. Paterson
Kucers The Use of Antibiotics Book PDF

Author : M. Lindsay Grayson,Sara E. Cosgrove,Suzanne Crowe,William Hope,James S. McCarthy,John Mills,Johan W. Mouton,David L. Paterson
Publisher : CRC Press
Page : 4894 pages
File Size : 40,7 Mb
Release : 2017-10-02
Category : Medical
ISBN : 9781498747967

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Kucers' The Use of Antibiotics by M. Lindsay Grayson,Sara E. Cosgrove,Suzanne Crowe,William Hope,James S. McCarthy,John Mills,Johan W. Mouton,David L. Paterson Pdf

Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

Fundamentals of Pharmacology for Children's Nurses

Ian Peate,Peter Dryden
Fundamentals of Pharmacology for Children s Nurses Book PDF

Author : Ian Peate,Peter Dryden
Publisher : John Wiley & Sons
Page : 452 pages
File Size : 49,5 Mb
Release : 2021-12-01
Category : Medical
ISBN : 9781119633235

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Fundamentals of Pharmacology for Children's Nurses by Ian Peate,Peter Dryden Pdf

Registered Nurses must have thorough knowledge of pharmacology, medicines administration, and the effects of medicines. Fundamentals of Pharmacology for Children's Nurses is written for nurses and allied health professionals involved in the care of children and young people (CYP) to focus exclusively on pharmacology. Filling a gap in current literature on the subject, this much-needed resource develops the competence and confidence required to prescribe, dispense, and administer medicines to children and young people. Emphasising the importance of patient-centered care to CYP, the text describes the role of the healthcare provider working with CYP and their families; explains how to use pharmaceutical and prescribing reference guides; discusses legal and ethical issues; examines pharmacodynamics and pharmacokinetics, and more. Helping readers respond appropriately and compassionately to the needs of those receiving care and their families, this textbook: Covers a wide range of medications used in diabetes, cancer, mental health, and other areas Features a wealth of full-colour images and numerous pedagogical tools including learning objectives, self-test questions, and reflective exercises to enable readers to contextualise and assess their knowledge Presents case studies to reinforce learning, and illustrate the application of theory to practice Provides authoritative and practical guidance on formulations, adverse drug reactions, analgesics, antibiotics, immunisations, and the medications most commonly used when providing care to CYP Includes access to a companion website with interactive MCQs, case studies, references, an image bank, and links to further reading and supplemental resources Fundamentals of Pharmacology for Children's Nurses is essential reading for undergraduate children's nursing students, trainee nursing associates, those undertaking healthcare programmes of study, as well as those seeking to better understand pharmacology.

Antibiotic Basics for Clinicians

Alan R. Hauser
Antibiotic Basics for Clinicians Book PDF

Author : Alan R. Hauser
Publisher : Wolters kluwer india Pvt Ltd
Page : 128 pages
File Size : 42,7 Mb
Release : 2020-04-01
Category : Medical
ISBN : 9789389702651

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Antibiotic Basics for Clinicians by Alan R. Hauser Pdf

Antibiotic Basics for Clinicians, South Asian Edition, simplifies the antibiotic selection process for the clinicians with up-to-date information on the latest and most clinically relevant antibacterial medications. This time-saving resource helps medical students master the rationale behind antibiotic selection for common

Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications

Hartmut Derendorf,Stephan Schmidt
Rowland and Tozer s Clinical Pharmacokinetics and Pharmacodynamics Concepts and Applications Book PDF

Author : Hartmut Derendorf,Stephan Schmidt
Publisher : Lippincott Williams & Wilkins
Page : 864 pages
File Size : 55,9 Mb
Release : 2019-07-11
Category : Medical
ISBN : 9781496385895

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Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications by Hartmut Derendorf,Stephan Schmidt Pdf

Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.

Fundamentals of Drug Delivery

Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Fundamentals of Drug Delivery Book PDF

Author : Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Publisher : John Wiley & Sons
Page : 580 pages
File Size : 47,6 Mb
Release : 2021-10-12
Category : Medical
ISBN : 9781119769606

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Fundamentals of Drug Delivery by Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang Pdf

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

The Ongoing Challenge of Antimicrobial Resistance, An Issue of Infectious Disease Clinics of North America, EBook

Richard R. Watkins,Robert A. Bonomo
The Ongoing Challenge of Antimicrobial Resistance An Issue of Infectious Disease Clinics of North America EBook Book PDF

Author : Richard R. Watkins,Robert A. Bonomo
Publisher : Elsevier Health Sciences
Page : 313 pages
File Size : 55,5 Mb
Release : 2020-11-11
Category : Medical
ISBN : 9780323759441

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The Ongoing Challenge of Antimicrobial Resistance, An Issue of Infectious Disease Clinics of North America, EBook by Richard R. Watkins,Robert A. Bonomo Pdf

Together with Consulting Editor Dr. Helen Boucher, Drs. Watkins and Bonomo have put together an issue of Infectious Disease Clinics of North America that provides the most current information on antibiotic resistance. Top experts have contributed clinical review articles that address the types of resistance based on drug class as well as emerging therapies and the future of telemedicine in the management of infections. The following topics are covered in this issue: The changing role of the clinical microbiology laboratory in defining resistance in gram-negatives; Extended-spectrum ß-lactamase-producing Enterobacteriaceae infections; Multidrug-resistant bacteria in the community; Resistance to polymyxins; Resistance in Vancomycin-resistant enterococci; Resistance to newer ß-lactamase inhibitors; Antibiotic-resistant infections in the immunocompromised host; Emerging therapies for MRSA infections; Drug-resistant tuberculosis; Aminoglycoside resistance; The role of antibiotic stewardship and telemedicine in the management of MDR infections; and Emerging issues in antifungal resistance. Readers will have the current information they need to better manage antibiotic-resistant infections in patients.

Basic Pharmacokinetics and Pharmacodynamics

Sara E. Rosenbaum
Basic Pharmacokinetics and Pharmacodynamics Book PDF

Author : Sara E. Rosenbaum
Publisher : John Wiley & Sons
Page : 576 pages
File Size : 49,5 Mb
Release : 2016-11-22
Category : Medical
ISBN : 9781119143161

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Basic Pharmacokinetics and Pharmacodynamics by Sara E. Rosenbaum Pdf

Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)