Galanin

Author : Tomas Hökfelt
Publisher : Springer Science & Business Media
Page : 286 pages
File Size : 46,8 Mb
Release : 2010-08-18
Category : Science
ISBN : 3034602286

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Galanin by Tomas Hökfelt Pdf

Galanin is a neuropeptide found both in the central and peripheral nervous system. The 29-amino acid peptide (named after its N-terminal glycine and C-terminal alanine) was identified in 1983 by its C-terminal amidation. This 'reverse' approach, that is to discover a substance through a distinct chemical feature, and only subsequently to characterize its biological activity, was novel and has been successful in the identification of several other peptides. After the structure of galanin was determined in 1983, functional studies were performed with material purified from natural sources until the synthetic form of the peptide became available. Galanin can act as transmitter, modulator and trophic factor, and is involved in a number of physiological processes such as hormone secretion, cardiovascular mechanisms, feeding and cognition. This peptide may also be of significance for a number of pathological processes/disorders including pain, depression, Alzheimer's disease, epilepsy, addiction and cancer. This wide diversity of actions is mediated by three galanin receptor subtypes. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.

Author : Nicholas Galanin
Publisher : Unknown
Page : 48 pages
File Size : 46,5 Mb
Release : 2021-06
Category : Electronic
ISBN : 1735642312

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Never Forget by Nicholas Galanin Pdf

Nicholas Galanin's forthcoming artist's book is dedicated to a single work, Never Forget-. This piece, beyond the visual component, is a call to action regarding the Land Back movement to acquire legal title to Indigenous homelands for tribal communities in the United States.

Author : Nicholas Galanin
Publisher : Unknown
Page : 144 pages
File Size : 49,6 Mb
Release : 2018-05-04
Category : Electronic
ISBN : 1732124108

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Nicholas Galanin by Nicholas Galanin Pdf

This publication spans the multiple generations and forms of media that inform Nicholas Galanin¿s ¿vessels of knowledge, culture and technology¿inherently political, generous, unflinching, and poetic.¿ He creates and speaks through multiple visual, audible, and tactile languages, a practice succinctly articulated through the introduction by artist Merritt Johnson, and further explored in conversation and critical analysis through scholars Negarra A. Kudumu and Erin Joyce. Galanin¿s practice includes numerous collaborations, including with his brother and fellow artist Jerrod Galanin under the moniker Leonard Getinthecar, through his participation in two artist collectives, Black Constellation, and Winter Count, and with the recently-announced group Indian Agent, along with Otis Calvin III, and Zak Dylan Wass¿their first album, Meditations in the Key of Red, was released in 2017.Through two- and three-dimensional works and time-based media, Galanin encourages reflection on cultural amnesia that actively obscures collective memory and acquisition of knowledge. Galanin¿s work has been exhibited extensively nationally and internationally. This is his first monograph.

Author : Remi Quirion,Anders Björklund,Tomas Hökfelt
Publisher : Gulf Professional Publishing
Page : 442 pages
File Size : 52,5 Mb
Release : 2000
Category : Neuropeptides
ISBN : 9780444505408

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Peptide Receptors by Remi Quirion,Anders Björklund,Tomas Hökfelt Pdf

Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.

Author : William D. Willis Jr.,Richard E. Coggeshall
Publisher : Springer Science & Business Media
Page : 604 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461500377

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Sensory Mechanisms of the Spinal Cord by William D. Willis Jr.,Richard E. Coggeshall Pdf

The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.

Author : Gernot Riedel,Bettina Platt
Publisher : Springer Science & Business Media
Page : 646 pages
File Size : 51,9 Mb
Release : 2004-11-03
Category : Medical
ISBN : 0306478625

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From Messengers to Molecules by Gernot Riedel,Bettina Platt Pdf

The decade of the brain has brought us a few steps closer to some of the key questions in neuroscience. The complexity of memory is seen on the systems and cellular level, and different types of memory are implemented in several cellular changes that can interact, or work independently. From Messengers to Molecules: Memories are Made of These, follows the arguments from different research teams for their particular area of expertise. All chapters are written to stand-alone and provide an up-to-date introduction to the topic for both specialists and novices alike. As a result, a comprehensive compendium covering cellular mechanisms contributing to memory formation in an unusual breadth has emerged. This books will be of interest to researchers working on the pharmacology, physiology and genetics of memory formation, clinicians memory disorders, industry and students in advanced courses in Neuroscience or Pharmacology.

Author : Tony M. Plant,Anthony J. Zeleznik
Publisher : Academic Press
Page : 2684 pages
File Size : 44,6 Mb
Release : 2014-11-15
Category : Science
ISBN : 9780123977694

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Knobil and Neill's Physiology of Reproduction by Tony M. Plant,Anthony J. Zeleznik Pdf

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context. The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field. Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction. Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.

Author : Dietmar Richter
Publisher : Springer Science & Business Media
Page : 370 pages
File Size : 54,8 Mb
Release : 2013-06-05
Category : Science
ISBN : 9783540494218

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Regulatory Peptides and Cognate Receptors by Dietmar Richter Pdf

In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro." Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a family of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g. CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.

Author : P. Michael Conn
Publisher : Academic Press
Page : 588 pages
File Size : 47,9 Mb
Release : 2013-10-22
Category : Nature
ISBN : 9781483268132

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Neuropeptide Technology by P. Michael Conn Pdf

Methods in Neurosciences, Volume 5: Neuropeptide Technology: Gene Expression and Neuropeptide Receptors discusses procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into two sections—neuropeptide gene expression and neuropeptide receptors. In these sections, this book specifically discusses the assays for peptide products of somatostatin gene expression; molecular assays for rat thyrotropin-releasing hormone gene; and structure, expression, and chromosomal localization of human gene. The gastrin-releasing peptide or mammalian bombesin; semiquantitative analysis of cellular somatostatin mRNA Levels; and atrial natriuretic factor receptor assays are also elaborated. This text likewise covers the receptors for opioid peptides in brain and autoradiography of somatostatin receptors in rat cerebellum. This publication is beneficial to neuroscientists and students intending to acquire knowledge of gene expression and neuropeptide receptors.

Author : T. W. Stone
Publisher : Taylor & Francis
Page : 418 pages
File Size : 46,7 Mb
Release : 1991
Category : Medical
ISBN : 085066828X

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Aspects of Synaptic Transmission by T. W. Stone Pdf

A collection of reviews on selected areas of synaptic transmission from neuroscientists in a number of areas of work in the nervous system and related disciplines. Five areas are covered - long-term potentiation, galanin, autonomic, opioids and 5-hydroxytryptamine.

Author : Anonim
Publisher : ScholarlyEditions
Page : 323 pages
File Size : 44,7 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481678063

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Neuropeptides—Advances in Research and Application: 2013 Edition by Anonim Pdf

Neuropeptides—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Urocortins. The editors have built Neuropeptides—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Urocortins in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neuropeptides—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : Unknown
Page : 1888 pages
File Size : 54,9 Mb
Release : 1998
Category : Medicine
ISBN : UIUC:30112041289510

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Cumulated Index Medicus by Anonim Pdf

Author : Terry W. Moody
Publisher : Springer Science & Business Media
Page : 454 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461528463

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Growth Factors, Peptides, and Receptors by Terry W. Moody Pdf

The Twelfth Annual Washington Spring Symposium on Health Sciences attracted over 300 scientists from 20 countries. It was held at the Lisner Auditorium of the George Washington University in Washington, D.C. during June 1-5, 1992. The theme of the meeting was "Growth Factors, Peptides, and Receptors," and speakers emphasized both basic and clinical research in these areas. The seven plenary sessions emphasized Peptides, Growth Factors, Peptide Receptors, Growth Factor Receptors, Second Messengers, Proliferation, and Clinical Correlations. The chapters in this volume are derived from each of these scientific sessions plus the poster and special sessions. The Abraham White Distinguished Scientist Award was presented to Dr. Solomon H. Snyder for his numerous contributions to the field of neurochemistry. He presented the keynote address "Nitric Oxide: A Novel Neuronal Messenger." Dr. Snyder discussed the pathway of nitric oxide (NO) synthesis by the enzyme NO synthase. Released NO may be responsible for the neuronal toxicity associated with NMDA, an excitatory amino acid analogue. Dr. Snyder noted that NO may be the first of a new class of transmitters, with carbon monoxide being another candidate. The Distinguished Public Service Award was presented to Senator Fritz Hollings in of his leadership and outstanding achievements in the United States Senate recognition and for his legislative support for biomedical research and education. In the symposium banquet address, Senator Hollings stressed the need for continued support of research to combat serious diseases such as cancer.

Author : Edwin E. Daniel
Publisher : CRC Press
Page : 563 pages
File Size : 44,6 Mb
Release : 2019-08-15
Category : Science
ISBN : 9781000696981

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Neuropeptide Function in the Gastrointestinal Tract by Edwin E. Daniel Pdf

First published in 1991: This book assimilates and evaluates the rapidly accumulating information regarding neuropeptides in the gut, their chemistry; genetic control; processing in enteric nerves; the projections of their nerves; their actions at the tissue, cell, and molecular levels; and their roles in controlling gut motility in health and disease. Neuropeptide Function in the Gastrointestinal Tract is directed to scientists in all disciplines who work with neuropeptides, as well as physiologists interested in the neural and smooth muscle actions of neuropeptides.

Author : Charles D. Barnes,Craig Johnston
Publisher : CRC Press
Page : 306 pages
File Size : 55,8 Mb
Release : 2020-07-24
Category : Medical
ISBN : 9781000159738

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Brain-gut Peptides and Reproductive Function by Charles D. Barnes,Craig Johnston Pdf

This book elucidates the role of brain-gut peptides in neuroendocrine regulation for understanding how these peptides interact with the reproductive neuroendocrine axis and for developing novel therapeutic agents for fertility or contraceptive therapies.