Peptide Receptors

Author : Dietmar Richter
Publisher : Springer Science & Business Media
Page : 370 pages
File Size : 51,7 Mb
Release : 2013-06-05
Category : Science
ISBN : 9783540494218

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Regulatory Peptides and Cognate Receptors by Dietmar Richter Pdf

In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro." Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a family of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g. CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.

Author : A. Bjorklund,T. Hokfelt,P. Quinton
Publisher : Elsevier
Page : 441 pages
File Size : 43,7 Mb
Release : 2002-12-13
Category : Medical
ISBN : 9780080538570

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Peptide Receptors, Part II by A. Bjorklund,T. Hokfelt,P. Quinton Pdf

Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.

Author : Remi Quirion,Anders Björklund,Tomas Hökfelt
Publisher : Gulf Professional Publishing
Page : 442 pages
File Size : 49,8 Mb
Release : 2000
Category : Neuropeptides
ISBN : 9780444505408

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Peptide Receptors by Remi Quirion,Anders Björklund,Tomas Hökfelt Pdf

Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.

Author : A. Bjorklund,T. Hokfelt,P. Quinton
Publisher : Elsevier
Page : 462 pages
File Size : 47,5 Mb
Release : 2000-06-08
Category : Science
ISBN : 0080538584

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Peptide Receptors by A. Bjorklund,T. Hokfelt,P. Quinton Pdf

During the last few years, the pace of research in the field of neuropeptide receptors has increased steadily: new neuropeptides were discovered, and the classification of receptor subtypes has been refined. It thus appeared essential to update the information. Peptide Receptors Part I summarizes current knowledge on ten distinct peptide families. This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry, and immunocytochemistry images. Application of these classical techniques and of new approaches such as transgenic and knock-out animals has revealed a distinct species and tissue specific variation in receptor subtypes expression and pharmacology in the mammalian central nervous system. The functional role of neuropeptides and their receptors in the CNS has been investigated thanks to the development of potent and selective receptor antagonists and agonists. The development of specific neuropeptide-related molecules will help to get a better understanding of receptor subtype physiology and neuronal distribution and may lead to innovative treatments in a variety of brain disorders.

Author : Richard E. Brown
Publisher : Cambridge University Press
Page : 434 pages
File Size : 40,7 Mb
Release : 1994-01-27
Category : Science
ISBN : 0521426650

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An Introduction to Neuroendocrinology by Richard E. Brown Pdf

This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

Author : Remi Quirion,Anders Björklund,Tomas Hökfelt
Publisher : Unknown
Page : 128 pages
File Size : 47,8 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:1281846791

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Peptide Receptors. Part II by Remi Quirion,Anders Björklund,Tomas Hökfelt Pdf

Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.

Author : Anonim
Publisher : ScholarlyEditions
Page : 225 pages
File Size : 52,6 Mb
Release : 2013-06-21
Category : Science
ISBN : 9781481678865

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Peptide Receptors—Advances in Research and Application: 2013 Edition by Anonim Pdf

Peptide Receptors—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Formyl Peptide Receptors. The editors have built Peptide Receptors—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Formyl Peptide Receptors in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Peptide Receptors—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : M. Y. Kalimi,J. R. Hubbard
Publisher : Walter de Gruyter GmbH & Co KG
Page : 732 pages
File Size : 47,6 Mb
Release : 2019-07-22
Category : Science
ISBN : 9783110850246

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Peptide Hormone Receptors by M. Y. Kalimi,J. R. Hubbard Pdf

No detailed description available for "Peptide Hormone Receptors".

Author : Lloyd D. Fricker
Publisher : Morgan & Claypool Publishers
Page : 123 pages
File Size : 52,8 Mb
Release : 2012
Category : Medical
ISBN : 9781615045068

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Neuropeptides and Other Bioactive Peptides by Lloyd D. Fricker Pdf

Neuropeptides and peptide hormones represent the largest class of chemical messengers that transmit information from one cell to another. In this review, several decades of research on peptides in cell-cell signaling are summarized, with a focus on neuropeptide discovery, biosynthesis, and function. In addition to covering the well-studied aspects of neuropeptides, emerging concepts are discussed, including classical versus non-classical neuropeptides and direct versus indirect neuropeptides. Other potential functions for peptides in intercellular and intracellular signaling are also discussed. Table of Contents: Overview of Neuropeptides / Neuropeptide Discovery / Neuropeptide Biosynthesis / Neuropeptides After Secretion: Receptors and Peptidases / Representative Neuropeptides / Concluding Remarks and Future Directions / References / Author Biography

Author : Stephen J. Peroutka
Publisher : CRC Press
Page : 372 pages
File Size : 41,6 Mb
Release : 1993-10-20
Category : Medical
ISBN : 0849383218

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Handbook of Receptors and Channels by Stephen J. Peroutka Pdf

The cloning, sequencing, and expression of a variety of membrane receptors and channels indicate the existence of at least four "superfamilies" of molecular structures that mediate signal transduction. Presently, more than 400 receptors have been cloned and sequenced. The Handbook of Receptors and Channels is the first handbook series to present the enormous amount of new molecular biological receptor data in a practical and useful format. Each volume in this remarkable series will focus on a specific molecular superfamily of receptors. Complete amino acid sequence information on all cloned receptors, as well as relevant pharmacological information, will be included. Furthermore, the format for each of the volumes will be consistent to allow for easy comparisons of different molecular subtypes for a given transmitter. G Protein-Coupled Receptors is the first volume in this new handbook series. Topics covered in future volumes include:

Author : David Raeburn,Mark A. Giembycz
Publisher : Springer
Page : 425 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783034873628

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Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction by David Raeburn,Mark A. Giembycz Pdf

Author : Michael B. Sporn,Anita B. Roberts
Publisher : Springer Science & Business Media
Page : 842 pages
File Size : 48,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461232100

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Peptide Growth Factors and Their Receptors I by Michael B. Sporn,Anita B. Roberts Pdf

This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, and numerous publications of reviews dealing with selected subsets of growth factors, the entire field has never been covered in a single treatise. It is essential to do this at the present time, as the number of journal articles on peptide growth factors now makes it almost impossible for anyone person to stay informed on this subject by reading the primary literature. At the same time it is becoming increasingly apparent that these of universal importance in biology and medicine and that the substances are original classification of these molecules, based on the laboratory setting of their discovery, as "growth factors," "lymphokines," "cytokines," or "colony stimulating factors," was quite artifactual; they are in fact the basis of a com mon language for intercellular communication. As a set they affect essentially every cell in the body, and in this regard they provide the basis to develop a unified science of cell biology, germane to all of biomedical research. This treatise is divided into four main sections. After three introductory chapters, its principal focus is the detailed description of each of the major peptide growth factors in 26 individual chapters.

Author : Anonim
Publisher : ScholarlyEditions
Page : 270 pages
File Size : 53,7 Mb
Release : 2012-12-26
Category : Science
ISBN : 9781464996368

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Peptide Receptors—Advances in Research and Application: 2012 Edition by Anonim Pdf

Peptide Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Peptide Receptors. The editors have built Peptide Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peptide Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Peptide Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 183 pages
File Size : 46,8 Mb
Release : 2012-01-09
Category : Science
ISBN : 9781464925856

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Peptide Receptors: Advances in Research and Application: 2011 Edition by Anonim Pdf

Peptide Receptors: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Peptide Receptors. The editors have built Peptide Receptors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peptide Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Peptide Receptors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : Unknown
Page : 423 pages
File Size : 46,8 Mb
Release : 2003
Category : Neuropeptides
ISBN : 0444903402

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Peptide Receptors by Anonim Pdf