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Gastrointestinal Pharmacology by Beverley Greenwood-Van Meerveld Pdf
This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
Gastrointestinal Pharmacology and Therapeutics by Gerald Friedman,Eugene D. Jacobson,Richard W. McCallum Pdf
This instrumental guide concentrates on the pharmacologic treatment for specific gastrointestinal situations, including motility disorders, pregnancy and cirrhosis. Primary emphasis is placed on the mechanisms of drugs and their therapeutic benefit. The book is divided in 15 sections covering: fundamentals of GI pharmacology; acid-related disorders; motility disorders; functional GI disorders; pain management; GI water flux; infections of the gut; acute and chronic noninfectious inflammatory states; pharmacologic therapy for hepatic disorders; biliary pharmacolgy; pancreas; pharmacology of GI vasculature; special issues; and drug assessment.
Author : M. Michael Wolfe,Robert C. Lowe Publisher : John Wiley & Sons Page : 222 pages File Size : 52,8 Mb Release : 2014-01-02 Category : Medical ISBN : 9781118481554
Pocket Guide to GastrointestinaI Drugs by M. Michael Wolfe,Robert C. Lowe Pdf
Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the world's leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: Introduction of drug class Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations Dosing information for each GI condition and on- and off-label use Consistent use of both generic and trade names throughout Specific reference to drug use in pediatric patients and during pregnancy Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists.
Handbook of Methods in Gastrointestinal Pharmacology by Timothy S. Gaginella Pdf
Gastroenterology has advanced through the development and application of increasingly sophisticated methods to measure changes in gastrointestinal function. Handbook of Methods in Gastrointestinal Pharmacology brings together details on commonly employed approaches in investigative gastroenterology. The book provides comprehensive coverage of methods and techniques used to investigate the mechanism of action of drugs on the GI tract. An integral part of each chapter is the discussion of development of techniques based upon physiologic mechanisms and principles in pharmacology. In vivo and in situ techniques involving whole animals, isolated tissue methodology, the use of single cell systems, and molecular biology approaches are covered. Illustrations provide a clear understanding of methodologies discussed. Emphasis is placed on advantages and disadvantages of each technique in answering specific research questions. Chapters are written by experts experienced in the techniques they discuss; many pioneered one or more widely used methods. The wide variety of topics included make the Handbook of Methods in Gastrointestinal Pharmacology useful to established investigators, research fellows, and graduate students. Additionally, reviewers of grants and manuscripts can use it to clarify questions that arise regarding appropriate use of a technique in a particular setting.
Drug Therapy for Gastrointestinal Disease by Michael J.G. Farthing,Anne B Ballinger Pdf
First published in 2001. This book is an invaluable clinical reference for the therapeutic management of gastrointestinal and liver diseases which the gastroenterologist and trainee encounter in their practice. Various drugs and their interactions with their intended site and also with other drugs are discussed from a practical point of view. This book is not a treatise on gastrointestinal pharmacology but a practical guide to the therapeutic use of GI drugs.
Biochemical Pharmacology as an Approach to Gastrointestinal Disorders by Timothy S. Gaginella,K. D. Rainsford,Gyula Mózsik Pdf
The Gastrointestinal Section of the International Union of Pharmacology (IUPHAR) was established in 1994 in Montreal, Canada. The establishment of the GI Section recognizes the international progress of gastrointestinal pharmacology, including basic and human studies. The Gastrointestinal Section of IUPHAR organized the first symposium, Biochemical Pharmacology as an Approach to Gastrointestinal Diseases: from Basic Science to Clinical Perspectives, on 10-12 October, 1995, in Pécs, Hungary. The main topics were: Gastrointestinal secretory and excretory fuctions Gastrointestinal motility Biochemical-pharmacological mechanisms in neural and hormonal actions involved in GI functions Main normal and pathological biochemical mechanisms in GI functions GI mucosal injury and protection Molecular mechanisms of premalignant and malignant diseases in GI tract Use of isolated cells and cell cultures in bioochemical-pharmacological studies to approach GI diseases. The presented papers are published in this book.
Pocket Handbook of GI Pharmacotherapeutics by George Y. Wu,Achilles Pappano Pdf
Although there are many pharmacology texts, and electronic sources of drug information relating to GI disorders, they are frequently encyclopedic, and practical information can be difficult to find. In Pocket Handbook of GI Pharmacotherapeutics, George Wu and Achilles Pappano create a text that combines the current treatment protocols and practical pharmacological information of prominent GI disorders for the first time. Chapters are disease specific, and contain treatment algorithms and therapy guides that present all the essential information in a compact, easy to reference handbook. The text contains practical clinical information in a highly accessible format, including keys for relative costs and the FDA pregnancy rating system for drug safety. Informative and unique, Pocket Handbook of GI Pharmacotherapeutics is a must have reference for any internist, gastroenterologist or general practioner who endeavors to provide better treatment of their patients.
Current Clinical Topics in Gastrointestinal Pharmacology by James H. Lewis,A. DuBois Pdf
This is an inaugural volume in a regular series of books devoted to selected topics in the field of pharmacologic therapeutics for gastrointestinal disease. Composed of concise practical chapters integrating physiology, pharmacokinetics, and clinical application of the most recent generation of GI drugs, the book is designed to offer the busy gastroenterologist, internist, and others an accessible update in this dynamic field.
Drug Development by Timothy S. Gaginella,Antonio Guglietta Pdf
The application of molecular techniques to gastroenterology continues to yield important advances in the development of drugs to treat gastrointestinal disorders. Important new drugs have emerged through the collaborative and complementary efforts of basic scientists, clinicians, and clinical researchers in academia and the pharmaceutical industry. The challenge has been exciting, with a few surprises along the way. Consider peptic ulcer disease as an example. The discovery of H receptors and the availability of potent and 2 selective H-receptor antagonists signaled the beginning of a new era 2 in the treatment of gastric hypersecretory states and peptic ulcers. Introduction of proton pump inhibitors offered another therapeutic option. Though H-receptor antagonists and proton pump inhibitors 2 are important and useful drugs, the discovery of the link between H. pylori infection and peptic ulcer disease has led to even more effective pharmacotherapeutic regimens. Our intent in Drug Development: Molecular Targets for GI Diseases is to bring together hands-on experts to review promising areas of gastrointestinal pharmacology. The contemporary topics covered, from a mechanistic viewpoint, are relevant to gastrointestinal inflammation and motility disorders. Authoritative opinions are offered on both future research directions and potential applications for new therapies.
Mediators and Drugs in Gastrointestinal Motility I by Anonim Pdf
Since the exhaustive Handbook of Physiology (Alimentary Canal, Section 6, Motility) edited by CHARLES F. CODE in 1968, no complete survey of the morphological basis and the physiological control of intestinal motility has been published, in spite of the enormous amount of new data in the literature on this topic. The new techniques and methodologies, the use of electron microscopy, radioimmunoassay and binding techniques, as weIl as ever more sophisticated electrophysiological procedures have made possible areal flood of discoveries in this field. Moreover, the possibility ofnew studies ofthe endocrine cells in biopsies of human intestinal mucosa even during routine endoscopies, has opened new horizons for gastroenterologists and generated a number of important contribu tions to our knowledge of the morphology and physiopathology of the gut. As usual, new discoveries have also revealed both ignorance and many new problems. For tbis reason, although many of the data reported in this volume can be considered as firmly established, others still require confirmation, and the results of new research in this field are awaited with extreme interest. Since advances are occurring so rapidly, even experts in the specific topics need frequent comprehensive reviews. To avoid an excessively large volume, considera tions ofthe pancreas, liver, and biliary system were not included in this Handbook, which, nevertheless, has attempted to off er the reader the essence of more than 1,500 papers.
Toxicology of the Gastrointestinal Tract by Shayne Cox Gad,Shayne C. Gad Pdf
Toxicology of the Gastrointestinal Tract focuses on the specifics of the mechanisms and adverse effects of xenobiotic agents and pharmaceuticals on the structure and function of the GI tract. The book focuses on a number of specific areas of intestinal research. Beginning with the well-recognized and major functions of nutrient absorption and its r
Toxicology of the Gastrointestinal Tract, Second Edition by Shayne Cox Gad Pdf
Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs
10 Years of Gastrointestinal and Hepatic Pharmacology by Angelo A. Izzo Pdf
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Introduction to Basics of Pharmacology and Toxicology by Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj Pdf
This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Serotonin and Gastrointestinal Function by Timothy S. Gaginella,James J. Galligan Pdf
Serotonin and Gastrointestinal Function provides a comprehensive review of current research into the mechanisms by which serotonin acts on gastrointestinal tissues. This book covers neurochemistry, physiology, pharmacology, and clinical issues relevant to serotonin in the gastrointestinal tract. The editors have brought together the most relevant information from the molecular to the clinical level. Each chapter is written by investigators experienced in research on serotonin's actions in the gut. This book will be useful to basic scientists, clinical investigators, graduate and postgraduate students.