Current Clinical Topics In Gastrointestinal Pharmacology
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Current Clinical Topics in Gastrointestinal Pharmacology by James H. Lewis,A. DuBois Pdf
This is an inaugural volume in a regular series of books devoted to selected topics in the field of pharmacologic therapeutics for gastrointestinal disease. Composed of concise practical chapters integrating physiology, pharmacokinetics, and clinical application of the most recent generation of GI drugs, the book is designed to offer the busy gastroenterologist, internist, and others an accessible update in this dynamic field.
Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract by Ludmila P. Filaretova,Koji Takeuchi Pdf
Up-to-date reviews on the mechanisms of gastrointestinal injury and protection In recent years, there have been significant advances both in understanding the mechanisms involved in gastrointestinal mucosal injury and protection, as well as in the development of successful strategies for prevention and treatment of gastrointestinal injury. Nevertheless, many people worldwide still suffer from gastrointestinal damage. This book contains contributions by an international panel of researchers in the form of up-to-date reviews on the mechanisms of gastrointestinal injury and protection. These are complemented by papers discussing how these new findings about cell/tissue injury and cytoprotection/organoprotection can be applied to the prevention and treatment of tissue damage in the gastrointestinal tract. Moreover, the publication includes a special chapter on Andre Robert, who has discovered the phenomenon of gastric cytoprotection. This publication will be of great interest for both basic and clinical researchers in gastroenterology and pharmacology, reviewing the advances made so far and pointing towards future developments.
Synthesis of Best-Seller Drugs by Ruben Vardanyan,Victor Hruby Pdf
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Gastrointestinal Pharmacology by Beverley Greenwood-Van Meerveld Pdf
This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
Recent Advances in the Pathophysiology and Management of Inflammatory Bowel Diseases and Digestive Endocrine Tumors by Michel Mignon,J. F. Colombel Pdf
John Libbey Eurotext is continuing to publish the gastroenterology course organised in Europe by leading international experts. The July 1999 course will examine the latest progress in treating the inflammatory bowel disease and digestive endocrine tumours with which doctors are often confronted. The following aspects are discussed: Epidemiological and genetic aspects; The immunological basis of inflammatory bowel disease; Extra-intestinal symptoms; Types of treatment. Edited by Professor Galmiche, chairman of the EAGE, the book gathers together biological and clinical information in a synthetic form aimed especially at young practitioners throughout Europe.
Toxicology of the Gastrointestinal Tract, Second Edition by Shayne Cox Gad Pdf
Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs
Edmunds' Pharmacology for the Primary Care Provider - E-Book by Constance G Visovsky,Cheryl H. Zambroski,Rebecca M. Lutz Pdf
Approx.860 pages Approx.860 pages NEW! Thoroughly updated content reflects the latest drug information and current thinking on pharmacologic management. NEW macro- and chapter-level organization is based on body systems rather than drug classes, for better coverage of the medications prescribed for the health problems affecting specific body systems. NEW and UNIQUE! Chapter format begins with an overview of anatomy, physiology, and disease processes — as opposed to drug classes or drug types — and then follows the World Health Organization’s Process for Rational Prescribing, using a six-step approach to drug selection and discussing first-, second-, and third-line treatments for each specific problem. NEW! Practical learning aids include: Black Box Warning boxes that draw attention to critical drug safety precautions. Clinical Guidelines: Bookmark This features that identify websites where updated clinical guidelines can be found. Medication Dosages tables that include dose ranges, maintenance doses, and, where appropriate, plans for dose escalation and de-escalation (e.g., corticosteroids). Practice Pearls boxes that highlight good prescribing practices, safety measures, follow-up recommendations, serum blood level monitoring, referrals to specialty providers, and other key prescriber tips. NEW! Prescribing Considerations unit addresses issues of medication adherence, prescription writing, cost, and quality assurance. NEW! Updated coverage of pain management reflects the current realities of substance use and the opioid crisis.
Theranostics, Gallium-68, and Other Radionuclides by Richard P. Baum,Frank Rösch Pdf
This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics – the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and treatment of neuroendocrine tumors and other diseases. In addition, new PET radiopharmaceuticals are considered, and the latest ideas and concepts, presented. Theranostics embodies both molecular and personalized medicine. It is at the cutting edge of medicine, and the contents of this volume will be of interest to chemists, physicians, and investigators dealing with generators, PET radiochemistry, molecular imaging, and radionuclide therapy.
Gastrointestinal Malignancies Gastrointestinal (GI) cancers are common diseases worldwide. About 400,000 patients are diagnosed with esophageal cancer worldwide each year and nearly 330,000 die for this disease. Roughly 870,000 patients are newly diagnosed each year with gastric cancer and over 600,000 die from the disease each year. And 940,000 new cases of colorectal cancer are diagnosed annually and 490,000 patients die from this disease. Management options for patients with GI cancer have undergone dramatic changes in the past decade. New cytotoxic agents, novel targeted agents, surgical and ablative options, as well as a new array of supportative medications have shown substantial progress. With the increased number of therapeutic options from which to choose, the clinician is better placed to offer effective therapy. At the same time the clinician is challenged to keep abreast of the rapidly changing treatment landscape and the newly emerging data that is shaping the options for treatment today and in the future. Gastrointestinal Malignancies provides a comprehensive and in-depth review of this group of malignancies. This volume reviews the current literature, provides critical evaluations of the data, and offers evidence-based recommendations. The editors and authors are leaders in their fields. The chapters update the current screening tools for colon cancers, assessment of predictive markers such as k-Ras and BRAF in the management of colon cancer as well as the state-of-the-art for use of both cytotoxic chemotherapy and the incorporation of newer biological therapies. About the Series: Emerging Cancer Therapeutics is an invited review publication providing a through analysis of key clinical research related to cancer therapeutics, including a discussion and assessment of current evidence, current clinical best practice, and likely near future developments. There is an emphasis throughout on multidisciplinary approaches to the specialty, as well as on quality and outcomes analysis. Published three times a year Emerging Cancer Therapeutics provides authoritative, thorough assessments of advances in therapeutics in all major areas of oncology, both solid and hematologic malignancies, with a focus on advances in medical and biological therapies with emerging clinical impact and encompassing new technologies with implications for management such as molecular imaging. Features of the Emerging Cancer Therapeutics include: Editorial board of nationally recognized experts across the spectrum of Cancer Therapeutics In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Cancer Therapeutics Issues edited by an authority in specific subject area Focuses on major topics in Cancer Therapeutics with in-depth articles covering advancs in clinical and translational research developments as well as clinical applications and experience Emphasizes multidisciplinary approaches to research and practice
Intestinal Immune System by Soichiro Miura,Ryota Hokari,Shunsuke Komoto Pdf
These negative regulatory mechanisms of the intestinal immune system are disturbed in certain disease conditions, causing the immunocompetent cells to respond to food components and commensal bacteria by becoming activated and to overproduce inflammatory cytokines and chemokines. These disease conditions include food allergies, such as celiac disease, and the inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, although their exact etiological mechanisms remain to be revealed. --Book Jacket.
Author : J. Larry Jameson,Leslie J. De Groot Publisher : Elsevier Health Sciences Page : 3076 pages File Size : 45,5 Mb Release : 2010-05-18 Category : Medical ISBN : 9781455711260
Endocrinology - E-Book by J. Larry Jameson,Leslie J. De Groot Pdf
ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. This reference is optimally designed to help you succeed in your demanding practice and ensure the best possible outcomes for every patient. Overcome virtually any clinical challenge with detailed, expert coverage of every area of endocrinology, authored by hundreds of leading luminaries in the field. Provide state-of-the-art care with comprehensive updates on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors ... brand-new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis ... expanded coverage of sports performance, including testosterone, androgen research, and bone growth and deterioration ... and the newest discoveries in genetics and how they affect patient care. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information more quickly, while still getting the complete coverage you expect.
Oxford Handbook of Gastrointestinal Nursing by Christine Norton Pdf
"This practical guide to all aspects of gastrointestinal nursing covers the treatment of a wide range of patients - from those suffering from minor and acute disorders, through chronic conditions, to those requiring major surgery and treatment for malignant disease. It summarizes the current state of knowledge in gastrointestinal nursing and provides concise, user-friendly guidelines on the management and treatment of patients with gastrointestinal disorders." "Written by practising nurses and subject experts, and incorporating their years of experience, the Oxford Handbook of Gastrointestinal Nursing is a unique and invaluable companion for practising nurses, and for all health care professionals who are involved in the care of patients with gastrointestinal disorders."--BOOK JACKET.
Guccione's Geriatric Physical Therapy E-Book by Dale Avers,Rita Wong Pdf
Offering a comprehensive look at physical therapy science and practice, Guccione’s Geriatric Physical Therapy, 4th Edition is a perfect resource for both students and practitioners alike. Year after year, this text is recommended as the primary preparatory resource for the Geriatric Physical Therapy Specialization exam. And this new fourth edition only gets better. Content is thoroughly revised to keep you up to date on the latest geriatric physical therapy protocols and conditions. Five new chapters are added to this edition to help you learn how to better manage common orthopedic, cardiopulmonary, and neurologic conditions; become familiar with functional outcomes and assessments; and better understand the psychosocial aspects of aging. In all, you can rely on Guccione’s Geriatric Physical Therapy to help you effectively care for today’s aging patient population. Comprehensive coverage of geriatric physical therapy prepares students and clinicians to provide thoughtful, evidence-based care for aging patients. Combination of foundational knowledge and clinically relevant information provides a meaningful background in how to effectively manage geriatric disorders Updated information reflects the most recent and relevant information on the Geriatric Clinical Specialty Exam. Standard APTA terminology prepares students for terms they will hear in practice. Expert authorship ensures all information is authoritative, current, and clinically accurate. NEW! Thoroughly revised and updated content across all chapters keeps students up to date with the latest geriatric physical therapy protocols and conditions. NEW! References located at the end of each chapter point students toward credible external sources for further information. NEW! Treatment chapters guide students in managing common conditions in orthopedics, cardiopulmonary, and neurology. NEW! Chapter on functional outcomes and assessment lists relevant scores for the most frequently used tests. NEW! Chapter on psychosocial aspects of aging provides a well-rounded view of the social and mental conditions commonly affecting geriatric patients. NEW! Chapter on frailty covers a wide variety of interventions to optimize treatment. NEW! Enhanced eBook version is included with print purchase, allowing students to access all of the text, figures, and references from the book on a variety of devices.