General Principles For Performing Aggregate Exposure And Risk Assessments

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EPA 630/R

Author : Anonim
Publisher : Unknown
Page : 94 pages
File Size : 48,7 Mb
Release : 1998
Category : Health risk assessment
ISBN : UOM:39015043186363

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EPA 630/R by Anonim Pdf

Principles and Practice of Mixtures Toxicology

Author : Moiz Mumtaz
Publisher : John Wiley & Sons
Page : 625 pages
File Size : 54,7 Mb
Release : 2011-05-23
Category : Science
ISBN : 9783527632114

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Principles and Practice of Mixtures Toxicology by Moiz Mumtaz Pdf

This first comprehensive treatment of the subject for more than a decade includes the latest research on nanoparticle toxicology. The practical handbook addresses all areas where toxic mixtures are encountered, from environmental via occupational to medical settings, giving special consideration to air and water, and to the specific requirements for study design in mixture toxicology. While no extensive prior knowledge or toxicological experience is required, the practice-oriented case studies and examples in the second part make this the ideal companion for the professional toxicologist in industry or healthcare institutions with little time for academic study.

Hayes' Principles and Methods of Toxicology

Author : A. Wallace Hayes,Claire L. Kruger
Publisher : CRC Press
Page : 2184 pages
File Size : 44,7 Mb
Release : 2014-10-10
Category : Medical
ISBN : 9781842145371

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Hayes' Principles and Methods of Toxicology by A. Wallace Hayes,Claire L. Kruger Pdf

Hayes' Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chap

Human and Ecological Risk Assessment

Author : Dennis J. Paustenbach
Publisher : John Wiley & Sons
Page : 1319 pages
File Size : 45,8 Mb
Release : 2024-04-23
Category : Technology & Engineering
ISBN : 9781119551102

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Human and Ecological Risk Assessment by Dennis J. Paustenbach Pdf

Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.

Occupational and Residential Exposure Assessment for Pesticides

Author : Claire A. Franklin,John P. Worgan
Publisher : John Wiley & Sons
Page : 438 pages
File Size : 50,5 Mb
Release : 2005-04-08
Category : Technology & Engineering
ISBN : 9780470012208

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Occupational and Residential Exposure Assessment for Pesticides by Claire A. Franklin,John P. Worgan Pdf

This timely publication concentrates on the exposure to pesticides by agricultural workers and residential users of pesticides through inhalation and physical contact. The book discusses more recently discovered risks such as pesticides on indoor carpets and includes new trends in data interpretation. Occupational & Residential Exposure Assessment for Pesticides complements the other title on pesticide exposure in the series - Pesticide Residues in Drinking Water, by Hamilton/Crossley and is a must for all professionals in the Pesticide Industry as well as academics.

A Framework to Guide Selection of Chemical Alternatives

Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Board on Chemical Sciences and Technology,Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Government and Industry Decisions
Publisher : National Academies Press
Page : 280 pages
File Size : 51,7 Mb
Release : 2014-10-29
Category : Science
ISBN : 9780309310161

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A Framework to Guide Selection of Chemical Alternatives by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Board on Chemical Sciences and Technology,Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Government and Industry Decisions Pdf

Historically, regulations governing chemical use have often focused on widely used chemicals and acute human health effects of exposure to them, as well as their potential to cause cancer and other adverse health effects. As scientific knowledge has expanded there has been an increased awareness of the mechanisms through which chemicals may exert harmful effects on human health, as well as their effects on other species and ecosystems. Identification of high-priority chemicals and other chemicals of concern has prompted a growing number of state and local governments, as well as major companies, to take steps beyond existing hazardous chemical federal legislation. Interest in approaches and policies that ensure that any new substances substituted for chemicals of concern are assessed as carefully and thoroughly as possible has also burgeoned. The overarching goal of these approaches is to avoid regrettable substitutions, which occur when a toxic chemical is replaced by another chemical that later proved unsuitable because of persistence, bioaccumulation, toxicity, or other concerns. Chemical alternative assessments are tools designed to facilitate consideration of these factors to assist stakeholders in identifying chemicals that may have the greatest likelihood of harm to human and ecological health, and to provide guidance on how the industry may develop and adopt safer alternatives. A Framework to Guide Selection of Chemical Alternatives develops and demonstrates a decision framework for evaluating potentially safer substitute chemicals as primarily determined by human health and ecological risks. This new framework is informed by previous efforts by regulatory agencies, academic institutions, and others to develop alternative assessment frameworks that could be operationalized. In addition to hazard assessments, the framework incorporates steps for life-cycle thinking - which considers possible impacts of a chemical at all stages including production, use, and disposal - as well as steps for performance and economic assessments. The report also highlights how modern information sources such as computational modeling can supplement traditional toxicology data in the assessment process. This new framework allows the evaluation of the full range of benefits and shortcomings of substitutes, and examination of tradeoffs between these risks and factors such as product functionality, product efficacy, process safety, and resource use. Through case studies, this report demonstrates how different users in contrasting decision contexts with diverse priorities can apply the framework. This report will be an essential resource to the chemical industry, environmentalists, ecologists, and state and local governments.

Risk Assessment for Chemicals in Drinking Water

Author : Robert A. Howd,Anna M. Fan
Publisher : John Wiley & Sons
Page : 392 pages
File Size : 44,9 Mb
Release : 2007-11-09
Category : Science
ISBN : 9780470173374

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Risk Assessment for Chemicals in Drinking Water by Robert A. Howd,Anna M. Fan Pdf

A comprehensive reference on state-of-the-art risk assessment methodologies for drinking water Risk Assessment for Chemicals in Drinking Water discusses the major steps and goals in risk assessments and suggests ways to improve the methodologies and accuracy, while consolidating up-to-date information on the current principles and practices in one authoritative reference. After an enlightening overview of risk assessment practices and regulatory guidelines, it: Includes descriptions of the use of variability analysis, exposure analysis, physiologically based pharmacokinetics, and modeling for both cancer and non-cancer endpoints Describes the practices of major organizations, including the U.S. EPA, Health Canada, World Health Organization, and California Office of Environmental Health Hazard Assessment Includes complete chapters on risk assessment for essential nutrients, arsenic, chloroform, and perchlorate Explains how to address susceptible sub-populations, including the elderly and infants and children, in risk assessments Covers the potential of using genomic and proteomic screens Addresses recent advances, emerging issues, and future challenges With contributions and perspectives from leading scientists, this is the definitive resource for health and environmental scientists, toxicologists, risk assessors and managers, regulators, consultants, and other professionals responsible for the safety of drinking water.

Principles of Characterizing and Applying Human Exposure Models

Author : International Program on Chemical Safety,World Health Organization,International Labour Organisation,United Nations Environment Programme,Inter-Organization Programme for the Sound Management of Chemicals
Publisher : World Health Organization
Page : 77 pages
File Size : 41,5 Mb
Release : 2005
Category : Medical
ISBN : 9789241563116

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Principles of Characterizing and Applying Human Exposure Models by International Program on Chemical Safety,World Health Organization,International Labour Organisation,United Nations Environment Programme,Inter-Organization Programme for the Sound Management of Chemicals Pdf

The objective of this manual is to provide guidance to risk assessors on the use of quantitative toxicokinetic and toxicodynamic data to address interspecies and interindividual differences in dose and concentration-response assessment. Section 1 focuses on the relevance of this guidance in the context of the broader risk assessment paradigm and other initiatives of the International Program on Chemical Safety (IPCS) project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals. Technical background material is presented in section 2, followed by generic guidance for the development of chemical-specific adjustment factors in section 3 and accompanying summary figures. Illustrative case-studies are included in an Appendix, and a glossary of terms is also provided.--Publisher's description.

Review of the Army's Technical Guides on Assessing and Managing Chemical Hazards to Deployed Personnel

Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on the Toxicological Risks to Deployed Military Personnel
Publisher : National Academies Press
Page : 215 pages
File Size : 49,8 Mb
Release : 2004-09-03
Category : Technology & Engineering
ISBN : 9780309092210

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Review of the Army's Technical Guides on Assessing and Managing Chemical Hazards to Deployed Personnel by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on the Toxicological Risks to Deployed Military Personnel Pdf

To guide mission planning, military decision makers need information on the health risks of potential exposures to individual soldiers and their potential impact on mission operations. To help with the assessment of chemical hazards, the U.S. Army Center for Health Promotion and Preventive Medicine developed three technical guides for characterizing chemicals in terms of their risks to the mission and to the health of the force. The report reviews these guides for their scientific validity and conformance with current risk-assessment practices. The report finds that the military exposure guidelines are appropriate (with some modification) for providing force health protection, but that for assessing mission risk, a new set of exposure guidelines is needed that predict concentrations at which health effects would degrade the performance of enough soldiers to hinder mission accomplishment.

Waste

Author : Trevor M. Letcher,Daniel Vallero
Publisher : Academic Press
Page : 604 pages
File Size : 53,7 Mb
Release : 2011-01-20
Category : Technology & Engineering
ISBN : 0123814766

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Waste by Trevor M. Letcher,Daniel Vallero Pdf

Waste: A Handbook for Management gives the broadest, most complete coverage of waste in our society. The book examines a wide range of waste streams, including: Household waste (compostable material, paper, glass, textiles, household chemicals, plastic, water, and e-waste) Industrial waste (metals, building materials, tires, medical, batteries, hazardous mining, and nuclear) Societal waste (ocean, military, and space) The future of landfills and incinerators Covering all the issues related to waste in one volume helps lead to comparisons, synergistic solutions, and a more informed society. In addition, the book offers the best ways of managing waste problems through recycling, incineration, landfill and other processes. Co-author Daniel Vallero interviewed on NBC's Today show for a segment on recycling Scientific and non-biased overviews will assist scientists, technicians, engineers, and government leaders Covers all main types of waste, including household, industrial, and societal Strong focus on management and recycling provides solutions

Air Pollution Calculations

Author : Daniel A. Vallero
Publisher : Elsevier
Page : 571 pages
File Size : 50,7 Mb
Release : 2019-05-03
Category : Medical
ISBN : 9780128149355

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Air Pollution Calculations by Daniel A. Vallero Pdf

Air Pollution Calculations introduces the equations and formulae that are most important to air pollution, but goes a step further. Most texts lack examples of how these equations and formulae apply to the quantification of real-world scenarios and conditions. The ample example calculations apply to current air quality problems, including emission inventories, risk estimations, biogeochemical cycling assessments, and efficiencies in air pollution control technologies. In addition, the book explains thermodynamics and fluid dynamics in step-by-step and understandable calculations using air quality and multimedia modeling, reliability engineering and engineering economics using practical examples likely to be encountered by scientists, engineers, managers and decision makers. The book touches on the environmental variables, constraints and drivers that can influence pollutant mass, volume and concentrations, which in turn determine toxicity and adverse outcomes caused by air pollution. How the pollutants form, move, partition, transform and find their fate are explained using the entire range of atmospheric phenomena. The control, prevention and mitigation of air pollution are explained based on physical, chemical and biological principles which is crucial to science-based policy and decision-making. Users will find this to be a comprehensive, single resource that will help them understand air pollution, quantify existing data, and help those whose work is impacted by air pollution. Explains air pollution in a comprehensive manner, enabling readers to understand how to measure and assess risks to human populations and ecosystems actually or potentially exposed to air pollutants Covers air pollution from a multivariate, systems approach, bringing in atmospheric processes, health impacts, environmental impacts, controls and prevention Facilitates an understanding of broad factors, like climate and transport, that influence patterns and change in pollutant concentrations, both spatially and over time

Science and Decisions

Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Improving Risk Analysis Approaches Used by the U.S. EPA
Publisher : National Academies Press
Page : 422 pages
File Size : 48,8 Mb
Release : 2009-03-24
Category : Political Science
ISBN : 9780309120463

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Science and Decisions by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Improving Risk Analysis Approaches Used by the U.S. EPA Pdf

Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Environmental Biotechnology

Author : Daniel Vallero
Publisher : Academic Press
Page : 746 pages
File Size : 40,7 Mb
Release : 2015-09-11
Category : Science
ISBN : 9780124078970

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Environmental Biotechnology by Daniel Vallero Pdf

Environmental Biotechnology: A Biosystems Approach, Second Edition presents valuable information on how biotechnology has acted as a vital buffer among people, pollution, and the environment. It answers the most important questions on the topic, including how, and why, a knowledge and understanding of the physical, chemical, and biological principles of the environment must be achieved in order to develop biotechnology applications. Most texts address either the applications or the implications of biotechnology. This book addresses both. The applications include biological treatment and other environmental engineering processes. The risks posed by biotechnologies are evaluated from both evidence-based and precautionary perspectives. Using a systems biology approach, the book provides a context for researchers and practitioners in environmental science that complements guidebooks on the necessary specifications and criteria for a wide range of environmental designs and applications. Users will find crucial information on the topics scientific researchers must evaluate in order to develop further technologies. Provides a systems approach to biotechnologies which includes the physical, biological, and chemical processes in context Presents relevant case studies on cutting-edge technologies, such as nanobiotechnologies and green engineering Addresses both the applications and implications of biotechnologies by following the lifecycle of a variety of established and developing biotechnologies Includes crucial information on the topics scientific researchers must evaluate in order to develop further technologies