Genes And Obesity

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The Genetics of Obesity

Author : Claude Bouchard
Publisher : CRC Press
Page : 262 pages
File Size : 50,6 Mb
Release : 2020-08-11
Category : Medical
ISBN : 9781000141603

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The Genetics of Obesity by Claude Bouchard Pdf

This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.

Genes and Obesity

Author : Anonim
Publisher : Academic Press
Page : 416 pages
File Size : 55,6 Mb
Release : 2010-12-17
Category : Science
ISBN : 0080962033

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Genes and Obesity by Anonim Pdf

A number of genes have been identified that are associated with an increased body mass index (BMI), the standard measurement of obesity. By analyzing these genes, researchers hope to gain a better understanding of what causes obesity and develop ways to tackle the problem. The study of genes and obesity could lead to new treatments. Genes and Obesity reviews the latest developments in the field. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

The Genetics of Obesity

Author : Stephanie Watson
Publisher : The Rosen Publishing Group, Inc
Page : 66 pages
File Size : 46,7 Mb
Release : 2008-08-15
Category : Juvenile Nonfiction
ISBN : 9781404217676

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The Genetics of Obesity by Stephanie Watson Pdf

Explains obesity and how genes can be linked to the condition.

The Genetics of Obesity

Author : Struan F.A. Grant
Publisher : Springer Science & Business Media
Page : 128 pages
File Size : 48,6 Mb
Release : 2013-11-09
Category : Medical
ISBN : 9781461486428

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The Genetics of Obesity by Struan F.A. Grant Pdf

In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first locus to be reported by this method to have a role in obesity but replication attempts have yielded inconsistent outcomes. The identification of the second locus, the fat mass- and obesity-associated gene (FTO), h has been more robustly observed by others. Studies from both FTO knock out and FTO overexpression mouse model support the fact that FTO is directly involved in the regulation of energy intake and metabolism in mice, where the lack of FTO expression leads to leanness while enhanced expression of FTO leads to obesity. Along with numerous other studies, a number of genetic variants have been established robustly in the context of obesity, giving us fresh insights into the pathogenesis of the disease. This book will give a comprehensive overview of efforts aimed at uncovering genetic variants associated with obesity, which have been particularly successful in the past 5 years with the advent of genome-wide association studies (GWAS). This book will cover this state of the art technology and its application to obesity in great detail. Topics covered will include genetics of childhood obesity, genetics of syndromic obesity, copy number variants and extreme obesity, co-morbidities of obesity genetics, and functional follow-up of genetic variants.​

Weight Management

Author : Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research,Subcommittee on Military Weight Management
Publisher : National Academies Press
Page : 277 pages
File Size : 49,7 Mb
Release : 2003-12-01
Category : Medical
ISBN : 9780309089968

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Weight Management by Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research,Subcommittee on Military Weight Management Pdf

The primary purpose of fitness and body composition standards in the U.S. Armed Forces has always been to select individuals best suited to the physical demands of military service, based on the assumption that proper body weight and composition supports good health, physical fitness, and appropriate military appearance. The current epidemic of overweight and obesity in the United States affects the military services. The pool of available recruits is reduced because of failure to meet body composition standards for entry into the services and a high percentage of individuals exceeding military weight-for-height standards at the time of entry into the service leave the military before completing their term of enlistment. To aid in developing strategies for prevention and remediation of overweight in military personnel, the U.S. Army Medical Research and Materiel Command requested the Committee on Military Nutrition Research to review the scientific evidence for: factors that influence body weight, optimal components of a weight loss and weight maintenance program, and the role of gender, age, and ethnicity in weight management.

Gene Eating

Author : Giles Yeo
Publisher : Simon and Schuster
Page : 352 pages
File Size : 55,6 Mb
Release : 2019-06-04
Category : Health & Fitness
ISBN : 9781643131696

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Gene Eating by Giles Yeo Pdf

In an age of misinformation and pseudo-science, the world is getting fatter and the diet makers are getting richer. So how do we break this cycle that’s literally killing us all?Drawing on the very latest science and his own genetic research at the University of Cambridge, Dr. Giles Yeo has written the seminal “anti-diet” diet book. Exploring the history of our food, debunking marketing nonsense, detoxifying diet advice, and confronting the advocates of clean eating, Giles translates his pioneering research into an engaging, must-read study of the human appetite.In a post-truth world, Gene Eating cuts straight to the data-driven facts. Only by understanding the physiology of our bodies, their hormonal functions, and their caloric needs can we overcome the mis- information of modern dieting trends, empower ourselves to make better decisions, and achieve healthy relationships with food, our bodies, and our weight.Inspiring and revelatory, filled with lively anecdotes and fascinating details, Gene Eating is an urgent and essential book that will change the way we eat.

Obesity and Cardiovascular Disease

Author : Malcolm K Robinson,Abraham Thomas
Publisher : CRC Press
Page : 480 pages
File Size : 49,7 Mb
Release : 2006-03-07
Category : Medical
ISBN : 9781420018905

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Obesity and Cardiovascular Disease by Malcolm K Robinson,Abraham Thomas Pdf

Although cardiovascular disease remains the leading proximate cause of death in the United States, it is now estimated that obesity may be equivalent to smoking as the leading cause of preventable death in America. In light of these statistics, this reference presents our current understanding of the epidemiology, pathology, and genetics of the obesity epidemic and its relationship to cardiovascular disease. It provides an evidence-based approach to the topic, as well as emphasizes a combined treatment strategy for patients suffering from both obesity and cardiovascular disease.

Principles of Nutrigenetics and Nutrigenomics

Author : Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier
Publisher : Academic Press
Page : 586 pages
File Size : 44,6 Mb
Release : 2019-09-22
Category : Medical
ISBN : 9780128045879

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Principles of Nutrigenetics and Nutrigenomics by Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier Pdf

Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

The Hungry Gene

Author : Ellen Ruppel Shell
Publisher : Grove Press
Page : 310 pages
File Size : 52,5 Mb
Release : 2003
Category : Health & Fitness
ISBN : 0802140335

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The Hungry Gene by Ellen Ruppel Shell Pdf

"The Hungry Gene" reveals the secret history and subtle politics behind the explosion of obesity in the United States and around the world.

Translational Cardiometabolic Genomic Medicine

Author : Annabelle Rodriguez-Oquendo
Publisher : Academic Press
Page : 354 pages
File Size : 44,8 Mb
Release : 2015-09-07
Category : Science
ISBN : 9780128004746

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Translational Cardiometabolic Genomic Medicine by Annabelle Rodriguez-Oquendo Pdf

Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome to the use of molecular diagnostic testing in predicting increased risk of cardiovascular diseases. Where applicable, this reference also includes chapters related to therapeutic options specifically aligned to molecular targets. Provides comprehensive research on translational genomic medicine Explains state-of-the-art genome editing for stem cells and mouse models with significant relevance to human cardiometabolic disease Includes discussions on the functional effects of single nucleotide polymorphisms and cardiometabolic diseases, stratified by sex and race Encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome

Obesity

Author : World Health Organization
Publisher : World Health Organization
Page : 267 pages
File Size : 46,9 Mb
Release : 2000
Category : Cooking
ISBN : 9789241208949

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Obesity by World Health Organization Pdf

This report issues a call for urgent action to combat the growing epidemic of obesity, which now affects developing and industrialized countries alike. Adopting a public health approach, the report responds to both the enormity of health problems associated with obesity and the notorious difficulty of treating this complex, multifactorial disease. With these problems in mind, the report aims to help policy-makers introduce strategies for prevention and management that have the greatest chance of success. The importance of prevention as the most sensible strategy in developing countries, where obesity coexists with undernutrition, is repeatedly emphasized. Recommended lines of action, which reflect the consensus reached by 25 leading authorities, are based on a critical review of current scientific knowledge about the causes of obesity in both individuals and populations. While all causes are considered, major attention is given to behavioural and societal changes that have increased the energy density of diets, overwhelmed sophisticated regulatory systems that control appetite and maintain energy balance, and reduced physical activity. Specific topics discussed range from the importance of fat content in the food supply as a cause of population-wide obesity, through misconceptions about obesity held by both the medical profession and the public, to strategies for dealing with the alarming prevalence of obesity in children. "... the volume is clearly written, and carries a wealth of summary information that is likely to be invaluable for anyone interested in the public health aspects of obesity and fatness, be they students, practitioner or researcher." - Journal of Biosocial Science

Why Calories Don't Count

Author : Giles Yeo
Publisher : Orion Spring
Page : 320 pages
File Size : 46,5 Mb
Release : 2021-06-17
Category : Health & Fitness
ISBN : 9781409199731

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Why Calories Don't Count by Giles Yeo Pdf

Calorie information is ubiquitous. On packaged food, restaurant menus and online recipes we see authoritative numbers that tell us the calorie count of what we're about to consume. And we treat these numbers as gospel; counting, cutting, intermittently consuming and, if you believe some 'experts' out there, magically making them disappear. We all know, and governments advise, that losing weight is just a matter of burning more calories than we consume. Here's the thing, however, that most people have no idea about. ALL of the calorie counts that you see everywhere today, are WRONG. In Why Calories Don't Count Dr Giles Yeo, obesity researcher at Cambridge University, challenges the conventional model and demonstrates that all calories are not created equal. He addresses why popular diets succeed, at least in the short term, and why they ultimately fail, and what your environment has to do with your bodyweight. Once you understand that calories don't count, you can begin to make different decisions about how you choose to eat, learning what you really need to be counting instead. Practical, science-based and full of illuminating anecdotes, this is the most entertaining dietary advice you'll ever read.

The Hungry Gene

Author : Ellen Ruppel Shell
Publisher : Unknown
Page : 294 pages
File Size : 50,5 Mb
Release : 2003-01
Category : Obesity
ISBN : 1843541416

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The Hungry Gene by Ellen Ruppel Shell Pdf

The Hungry Gene takes an unflinching look at the spread of obesity, the most vexing scientific mysteries of our time. Acclaimed science journalist Ellen Ruppel Shell reveals the existence of a gene that causes obesity and meets the scientists working to isolate it. She looks at how medicine is dealing with the fat crisis with radical surgical techniques and takes aim at the culture behind the crisis - suburban sedentary lifestyle and the fast-food market that preys on the jammed schedules of today's two-income families.Weaving cutting-edge science, history and personal stories, the narrative builds to a powerful conclusion that reveals how we can beat obesity before it flattens us. Gripping and provocative, The Hungry Gene is the unsettling account of how the western world got fat - and what we can do about it.

Nutrition in the Prevention and Treatment of Abdominal Obesity

Author : Ronald Ross Watson
Publisher : Elsevier
Page : 560 pages
File Size : 55,6 Mb
Release : 2014-02-26
Category : Medical
ISBN : 9780124079342

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Nutrition in the Prevention and Treatment of Abdominal Obesity by Ronald Ross Watson Pdf

Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases. Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal fat: cardiology, diabetes research, studies of lipids, endocrinology and metabolism, nutrition, obesity, and exercise physiology. They have contributed chapters that define a range of dietary approaches to reducing risk and associated chronic diseases. They begin by defining visceral obesity and its major outcomes; they also discuss the importance and the challenges of dietary approaches to reduce abdominal obesity, as compared to clinical approaches, with major costs and risks. Offers detailed, well-documented reviews outlining the various dietary approaches to visceral obesity with their benefits and failures Includes chapters on types of foods, exercise, and supplements in reducing obesity and its chronic clinical companions, especially diabetes and cardiovascular disease Helps nutritionists, dieticians, and healthcare providers approach patients in making decision about nutritional therapies and clinical treatments for abdominal obesity, from an evidence-based perspective

Genes, Behavior, and the Social Environment

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health
Publisher : National Academies Press
Page : 385 pages
File Size : 48,6 Mb
Release : 2006-12-07
Category : Social Science
ISBN : 9780309101967

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Genes, Behavior, and the Social Environment by Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health Pdf

Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.