The Genetics Of Obesity

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The Genetics of Obesity

Claude Bouchard
The Genetics of Obesity Book PDF

Author : Claude Bouchard
Publisher : CRC Press
Page : 262 pages
File Size : 41,8 Mb
Release : 2020-08-11
Category : Medical
ISBN : 9781000141603

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The Genetics of Obesity by Claude Bouchard Pdf

This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.

The Genetics of Obesity

Stephanie Watson
The Genetics of Obesity Book PDF

Author : Stephanie Watson
Publisher : The Rosen Publishing Group, Inc
Page : 66 pages
File Size : 52,9 Mb
Release : 2008-08-15
Category : Juvenile Nonfiction
ISBN : 9781404217676

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The Genetics of Obesity by Stephanie Watson Pdf

Explains obesity and how genes can be linked to the condition.

Genes and Obesity

Anonim
Genes and Obesity Book PDF

Author : Anonim
Publisher : Academic Press
Page : 416 pages
File Size : 51,7 Mb
Release : 2010-12-17
Category : Science
ISBN : 0080962033

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Genes and Obesity by Anonim Pdf

A number of genes have been identified that are associated with an increased body mass index (BMI), the standard measurement of obesity. By analyzing these genes, researchers hope to gain a better understanding of what causes obesity and develop ways to tackle the problem. The study of genes and obesity could lead to new treatments. Genes and Obesity reviews the latest developments in the field. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

Genetics of Obesity Syndromes

Philip R. Beales,I. Sadaf Farooqi,Stephen O'Rahilly
Genetics of Obesity Syndromes Book PDF

Author : Philip R. Beales,I. Sadaf Farooqi,Stephen O'Rahilly
Publisher : Oxford University Press
Page : 300 pages
File Size : 42,9 Mb
Release : 2008-08-29
Category : Medical
ISBN : 9780199719860

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Genetics of Obesity Syndromes by Philip R. Beales,I. Sadaf Farooqi,Stephen O'Rahilly Pdf

Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes in which obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of the obesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much a reference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.

The Genetics of Obesity

Struan F.A. Grant
The Genetics of Obesity Book PDF

Author : Struan F.A. Grant
Publisher : Springer Science & Business Media
Page : 128 pages
File Size : 43,5 Mb
Release : 2013-11-09
Category : Medical
ISBN : 9781461486428

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The Genetics of Obesity by Struan F.A. Grant Pdf

In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first locus to be reported by this method to have a role in obesity but replication attempts have yielded inconsistent outcomes. The identification of the second locus, the fat mass- and obesity-associated gene (FTO), h has been more robustly observed by others. Studies from both FTO knock out and FTO overexpression mouse model support the fact that FTO is directly involved in the regulation of energy intake and metabolism in mice, where the lack of FTO expression leads to leanness while enhanced expression of FTO leads to obesity. Along with numerous other studies, a number of genetic variants have been established robustly in the context of obesity, giving us fresh insights into the pathogenesis of the disease. This book will give a comprehensive overview of efforts aimed at uncovering genetic variants associated with obesity, which have been particularly successful in the past 5 years with the advent of genome-wide association studies (GWAS). This book will cover this state of the art technology and its application to obesity in great detail. Topics covered will include genetics of childhood obesity, genetics of syndromic obesity, copy number variants and extreme obesity, co-morbidities of obesity genetics, and functional follow-up of genetic variants.​

Translational Cardiometabolic Genomic Medicine

Annabelle Rodriguez-Oquendo
Translational Cardiometabolic Genomic Medicine Book PDF

Author : Annabelle Rodriguez-Oquendo
Publisher : Academic Press
Page : 354 pages
File Size : 47,9 Mb
Release : 2015-09-07
Category : Science
ISBN : 9780128004746

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Translational Cardiometabolic Genomic Medicine by Annabelle Rodriguez-Oquendo Pdf

Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome to the use of molecular diagnostic testing in predicting increased risk of cardiovascular diseases. Where applicable, this reference also includes chapters related to therapeutic options specifically aligned to molecular targets. Provides comprehensive research on translational genomic medicine Explains state-of-the-art genome editing for stem cells and mouse models with significant relevance to human cardiometabolic disease Includes discussions on the functional effects of single nucleotide polymorphisms and cardiometabolic diseases, stratified by sex and race Encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome

Gene Eating

Giles Yeo
Gene Eating Book PDF

Author : Giles Yeo
Publisher : Simon and Schuster
Page : 352 pages
File Size : 49,9 Mb
Release : 2019-06-04
Category : Health & Fitness
ISBN : 9781643131696

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Gene Eating by Giles Yeo Pdf

In an age of misinformation and pseudo-science, the world is getting fatter and the diet makers are getting richer. So how do we break this cycle that’s literally killing us all?Drawing on the very latest science and his own genetic research at the University of Cambridge, Dr. Giles Yeo has written the seminal “anti-diet” diet book. Exploring the history of our food, debunking marketing nonsense, detoxifying diet advice, and confronting the advocates of clean eating, Giles translates his pioneering research into an engaging, must-read study of the human appetite.In a post-truth world, Gene Eating cuts straight to the data-driven facts. Only by understanding the physiology of our bodies, their hormonal functions, and their caloric needs can we overcome the mis- information of modern dieting trends, empower ourselves to make better decisions, and achieve healthy relationships with food, our bodies, and our weight.Inspiring and revelatory, filled with lively anecdotes and fascinating details, Gene Eating is an urgent and essential book that will change the way we eat.

Obesity and Cardiovascular Disease

Malcolm K Robinson,Abraham Thomas
Obesity and Cardiovascular Disease Book PDF

Author : Malcolm K Robinson,Abraham Thomas
Publisher : CRC Press
Page : 480 pages
File Size : 46,6 Mb
Release : 2006-03-07
Category : Medical
ISBN : 9781420018905

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Obesity and Cardiovascular Disease by Malcolm K Robinson,Abraham Thomas Pdf

Although cardiovascular disease remains the leading proximate cause of death in the United States, it is now estimated that obesity may be equivalent to smoking as the leading cause of preventable death in America. In light of these statistics, this reference presents our current understanding of the epidemiology, pathology, and genetics of the obesity epidemic and its relationship to cardiovascular disease. It provides an evidence-based approach to the topic, as well as emphasizes a combined treatment strategy for patients suffering from both obesity and cardiovascular disease.

Weight Management

Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research,Subcommittee on Military Weight Management
Weight Management Book PDF

Author : Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research,Subcommittee on Military Weight Management
Publisher : National Academies Press
Page : 277 pages
File Size : 46,6 Mb
Release : 2003-12-01
Category : Medical
ISBN : 9780309089968

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Weight Management by Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research,Subcommittee on Military Weight Management Pdf

The primary purpose of fitness and body composition standards in the U.S. Armed Forces has always been to select individuals best suited to the physical demands of military service, based on the assumption that proper body weight and composition supports good health, physical fitness, and appropriate military appearance. The current epidemic of overweight and obesity in the United States affects the military services. The pool of available recruits is reduced because of failure to meet body composition standards for entry into the services and a high percentage of individuals exceeding military weight-for-height standards at the time of entry into the service leave the military before completing their term of enlistment. To aid in developing strategies for prevention and remediation of overweight in military personnel, the U.S. Army Medical Research and Materiel Command requested the Committee on Military Nutrition Research to review the scientific evidence for: factors that influence body weight, optimal components of a weight loss and weight maintenance program, and the role of gender, age, and ethnicity in weight management.

Why Calories Don't Count

Giles Yeo
Why Calories Don t Count Book PDF

Author : Giles Yeo
Publisher : Orion Spring
Page : 320 pages
File Size : 54,6 Mb
Release : 2021-06-17
Category : Health & Fitness
ISBN : 9781409199731

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Why Calories Don't Count by Giles Yeo Pdf

Calorie information is ubiquitous. On packaged food, restaurant menus and online recipes we see authoritative numbers that tell us the calorie count of what we're about to consume. And we treat these numbers as gospel; counting, cutting, intermittently consuming and, if you believe some 'experts' out there, magically making them disappear. We all know, and governments advise, that losing weight is just a matter of burning more calories than we consume. Here's the thing, however, that most people have no idea about. ALL of the calorie counts that you see everywhere today, are WRONG. In Why Calories Don't Count Dr Giles Yeo, obesity researcher at Cambridge University, challenges the conventional model and demonstrates that all calories are not created equal. He addresses why popular diets succeed, at least in the short term, and why they ultimately fail, and what your environment has to do with your bodyweight. Once you understand that calories don't count, you can begin to make different decisions about how you choose to eat, learning what you really need to be counting instead. Practical, science-based and full of illuminating anecdotes, this is the most entertaining dietary advice you'll ever read.

Obesity and Metabolism

Márta Korbonits
Obesity and Metabolism Book PDF

Author : Márta Korbonits
Publisher : Karger Medical and Scientific Publishers
Page : 305 pages
File Size : 49,6 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9783805584296

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Obesity and Metabolism by Márta Korbonits Pdf

It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.

Genes, Behavior, and the Social Environment

Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health
Genes Behavior and the Social Environment Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health
Publisher : National Academies Press
Page : 385 pages
File Size : 41,7 Mb
Release : 2006-12-07
Category : Social Science
ISBN : 9780309101967

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Genes, Behavior, and the Social Environment by Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health Pdf

Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.

Principles of Nutrigenetics and Nutrigenomics

Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier
Principles of Nutrigenetics and Nutrigenomics Book PDF

Author : Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier
Publisher : Academic Press
Page : 586 pages
File Size : 53,6 Mb
Release : 2019-09-22
Category : Medical
ISBN : 9780128045879

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Principles of Nutrigenetics and Nutrigenomics by Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier Pdf

Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Genetics of Endocrine Diseases and Syndromes

Peter Igaz,Attila Patócs
Genetics of Endocrine Diseases and Syndromes Book PDF

Author : Peter Igaz,Attila Patócs
Publisher : Springer Nature
Page : 476 pages
File Size : 52,8 Mb
Release : 2019-10-06
Category : Science
ISBN : 9783030259051

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Genetics of Endocrine Diseases and Syndromes by Peter Igaz,Attila Patócs Pdf

This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. It covers both the molecular and clinical consequences of these genetic defects, as well as the relevance for clinical care, highlighting issues of genetic counseling. Several endocrine diseases have a genetic background, and contemporary research in the field plays a crucial role in the clinical care of endocrine diseases. In recent years, there have been major developments in our understanding of the genetic basis of endocrine diseases. Several novel genes and mutations predisposing individuals to monogenic endocrine diseases have been discovered, and with the advent of next generation sequencing, a huge amount of new data has become available. Further, novel molecular mechanisms, such as genomic imprinting, have been implicated in the pathogenesis of endocrine diseases. A better understanding of the genetic background of these diseases is relevant not only from the research perspective, but also in terms of clinical care. As such, this book is an essential read for both researchers and clinicians working in the field.

The Evolution of Obesity

Michael L. Power,Jay Schulkin
The Evolution of Obesity Book PDF

Author : Michael L. Power,Jay Schulkin
Publisher : JHU Press
Page : 406 pages
File Size : 44,9 Mb
Release : 2013-02
Category : Medical
ISBN : 9781421409603

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The Evolution of Obesity by Michael L. Power,Jay Schulkin Pdf

Draws on popular examples and sound science to explain our expanding waistlines and to discuss the consequences of being overweight for different demographic groups. Reviews the various studies of human and animal fat use and storage, including those that examine fat deposition and metabolism in men and women; chronicle cultural differences in food procurement, preparation, and consumption; and consider the influence of sedentary occupations and lifestyles.